ライフサイエンスコーパス: cell stage

1 ess into the blastocoel at the 6th cycle (62-cell stage).

2 g the 16-cell and subsequently during the 20-cell stages).

3 and the nucleolus also appeared around the 8-cell stage.

4 ls were arrested at the B220(+)CD19(-) pro-B-cell stage.

5 rlier in human embryos at the four- to eight-cell stage.

6 t becomes depleted in the posterior by the 4-cell stage.

7 ker protein, arrest development at the pre-B-cell stage.

8 ells were first found at the double-positive cell stage.

9 t fail to progress beyond the transitional B cell stage.

10 mally upregulated TET3 was detected at the 4-cell stage.

11 ce of TET3 was high only at the zygote and 2-cell stage.

12 mocyte maturation up to and beyond the pro-T-cell stage.

13 support embryonic development beyond the two-cell stage.

14 ne segment-cleavage events at the immature B cell stage.

15 at the common lymphoid progenitor to preproB cell stage.

16 ent that in most cases was arrested at the 2-cell stage.

17 ment, and subsequent transition to the pre-B cell stage.

18 nificantly reduced from the 2-cell to the 48-cell stage.

19 L chain loci become accessible at the pre-B cell stage.

20 at the common lymphoid progenitor to preproB cell stage.

21 the common lymphoid progenitor (CLP) LY6D(+) cell stage.

22 l (mature) B cell value by the cycling pre-B cell stage.

23 ocus in zebrafish after injection at the one-cell stage.

24 nd the germ line are determined by the eight-cell stage.

25 in a severe developmental block at the pre-B cell stage.

26 d/or in the maintenance of a stem/progenitor cell stage.

27 (KO/KO) mutant embryos died before the 32-64-cell stage.

28 in peripheral B cell development at the T1 B cell stage.

29 es, with rapidly declining levels at the two-cell stage.

30 mbryo occurs in two distinct phases at the 8-cell stage.

31 as they transition from the RTE to the MN T cell stage.

32 performed ablation experiments at the eight-cell stage.

33 ing zygotic genome activation (ZGA) at the 2-cell stage.

34 ve splice form bias hierarchy, regardless of cell stage.

35 lumen or multiple-lumen phenotype at the two-cell stage.

36 blocks B cell specification at the prepro-B cell stage.

37 early embryonic lethality prior to the eight-cell stage.

38 cell-fate switch occurred at the pIIa-pIIb 2-cell stage.

39 tmentalization can be found as late as the 8-cell stage.

40 d domains (DMDs) of imprinted genes at the 8-cell stage.

41 rotein levels are heterogeneous at the eight-cell stage.

42 y during embryonic development before the 16-cell stage.

43 and that Padi6-/- embryos arrest at the two-cell stage.

44 es secondary rearrangement at the immature B-cell stage.

45 -) embryos failed to survive after the eight-cell stage.

46 2 is required for development beyond the two-cell stage.

47 to downregulate SKN-1 from the 12- to the 28-cell stage.

48 along the animal-vegetal axis prior to the 8-cell stage.

49 mental fate and potency as early as the four-cell stage.

50 h surprisingly continued to divide to the 16-cell stage.

51 he presumptive oral ectoderm at about the 30-cell stage.

52 of development and disappeared by the eight cell stage.

53 B-cell development to proceed from the pro-B-cell stage.

54 led their progression from the 2-cell to 4-8-cell stage.

55 50 is sharply up-regulated at the immature B cell stage.

56 in C. elegans embryos beginning near the 100-cell stage.

57 ve selection occur within the transitional B cell stage.

58 ic ABa/ABp blastomere identities at the four-cell stage.

59 nerated without passing through the effector cell stage.

60 iates floxed gene recombination at the pro-B-cell stage.

61 ell development was blocked at the pre-pro-B-cell stage.

62 established with a drastic increase at the 8-cell stage.

63 Oct4 contributes to the DHSs gained at the 8-cell stage.

64 ulthood by vegfaa mRNA injections at the one-cell stage.

65 wly formed B cells until the ultimate plasma cell stage.

66 e Caenorhabditis elegans embryo up to the 16-cell stage.

67 rease in 5-methylcytosine (5mC) at the eight-cell stage.

68 rs in the bone marrow beginning at the pro-B cell stage.

69 ferentiation is arrested at the guard mother cell stage.

70 gly is not asymmetrically localized at the 4-cell stage.

71 urther developed to the B220(+)CD19(+) pro-B-cell stage.

72 cell divisions, starting at the blastula 64-cell stage.

73 opment in the bone marrow at the small pre-B cell stage.

74 ween organisms, but is usually after the two-cell stage.

75 cell development between the pro-B and pre-B cell stages.

76 nd aPKC and cell compaction at the 8- and 16-cell stages.

77 oliferation at the CD34(+) and CD34(-) pro-B cell stages.

78 by conditionally deleting Mcl-1 at various T cell stages.

79 re, during the late 16-cell through early 24-cell stages.

80 3, TN4, and double positive (CD4(+), CD8(+)) cell stages.

81 mmetry of SKN-1 accumulation at the 2- and 4-cell stages.

82 ogonia, but principally to only the 4- and 8-cell stages.

83 the earliest into the most mature erythroid cell stages.

84 profile compared with lymphomas from other B-cell stages.

85 SI was also studied for embryos at different cell stages (1-, 2-, 4-, 8-, and 16-cell stage) to inves

86 Only 53% and 8% of mature eggs reached the 2-cell stage after IVF in animals receiving a 3 and 5 days

87 injected embryos with azidosugars at the one-cell stage, allowed the zebrafish to develop, and detect

88 val of the first quartet micromeres at the 8-cell stage also leads to the development of radialized l

89 I-I proteins are detected as early as at two-cell stage and exhibit distinct and dynamic expression p

90 tosis for nutrient acquisition at its single-cell stage and for antibacterial defense at its multicel

91 anscription factor GATA3 is induced at the 4-cell stage and is consistently present during pre-implan

92 ays the progression from the 2-cell to the 4-cell stage and produces blastocysts that fail to implant

93 In spite of a severe block at the pro-B cell stage and profound B cell lymphopenia, significant

94 that are expressed after the KIT+ progenitor cell stage and remain expressed through CD19+ and AICDA+

95 g, host HSCs arrested at the short-term stem cell stage and remained in the marrow in a quiescent cel

96 ks early B cell development at the pre-pro-B cell stage and renders B cell progenitors unresponsive t

97 differentiation events as early as the eight-cell stage and soon thereafter for proper division of th

98 genome activation and DHS formation at the 2-cell stage and that Oct4 contributes to the DHSs gained

99 p300 are partially limiting beyond the pro-B-cell stage and that other coactivators in B cells cannot

100 ocysts and TET1 protein was present at the 4-cell stage and the blastocysts.

101 hat cell polarity is established by the four-cell stage and then reiteratively lost during subsequent

102 polarisation of blastomeres at the 8- and 16-cell stage and then the maintenance of trophectoderm lin

103 or three cycles after the 5th cell cycle (32-cell stage) and ingress into the blastocoel at the 6th c

104 utoreactive cells at the emergent immature B cell stage, and a relaxed selection for peripheral toler

105 activated in mouse embryos as early as the 4-cell stage, and becomes spatially restricted by late bla

106 was detectable at differing levels by the 64 cell stage, and IP(3)-induced Ca(2+) transients could be

107 r Aurkb nor Aurkc is expressed after the one-cell stage, and that AURKC is more stable during maturat

108 BAFFR is already expressed at the immature B cell stage, and that the prosurvival protein Bcl-2 does

109 h1-/- embryos could not survive beyond the 2-cell stage, and underwent apoptotic death.

110 hese data further support the development of cell-, stage-, and/or receptor-specific anti-TNF-alpha t

111 vantage beginning at the late transitional B-cell stage; and (3) a similar in vivo selective advantag

112 ydrogenase, and aconitase, resulted in a one-cell stage arrest before entry into mitosis: pronuclear

113 ation mutation (DeltaN-Zfp36l2) leads to two-cell stage arrest of embryos derived from the homozygous

114 -1 remained inhibitory-phosphorylated in one-cell stage-arrested embryos, indicative of a G2-like arr

115 d between the T2 and the mature follicular B cell stage as a result of a partial defect in BCR signal

116 gnal transduction were up-regulated at the 8-cell stage as compared with 8-cell embryos treated with

117 B cell differentiation to the CD19(+) pro-B cell stage as well as survival of CD19(+) pro-B cells.

118 In C. elegans the 4-cell stage blastomere EMS is an endomesodermal precursor

119 al when confined to half of the embryo via 2-cell stage blastomere injections, the latter does not pr

120 The 8-cell stage blastomere MS is primarily a mesodermal precu

121 stent with a random distribution up to the 8-cell stage but not at later stages.

122 ivity are mostly deleted before the mature B cell stage, but are positively selected and expanded in

123 ial deletion at the transitional to mature B cell stage, but become Env(-) upon receptor editing.

124 regulatory checkpoint at the early preplasma cell stage by a self-Ag-dependent mechanism.

125 itis elegans embryo is elaborated at the one-cell stage by the polarization of the partitioning (PAR)

126 genes are established at the embryonic stem cell stage by two parallel, but distinct, repressor path

127 s repressed at the pro-B cell and immature B cell stages by the kinase Akt through its 'antagonism' o

128 The two-cell stage Caenorhabditis elegans embryo divides asynchr

129 assessment of polarity establishment in one-cell stage Caenorhabditis elegans embryos by combining t

130 rtical response to laser ablation in the one-cell-stage Caenorhabditis elegans embryo and in the gast

131 mbranes, and also between cells of different cell stage, cell and tissue types, and organisms.

132 rise to the D quadrant at the two- and four-cell stages (cells ultimately generating the 4d mesentob

133 ydrogenase is transiently nuclear at the 4/8-cell stage coincident with timing of human embryonic gen

134 zes to hermaphrodite X chromosomes at the 30-cell stage, coincident with a developmental transition f

135 ne in healthy embryos was initiated at the 2-cell stage, coincident with embryonic genome activation

136 ed beta-catenin which, by as early as the 32-cell stage, commits nuclei in prospective dorsal lineage

137 ith embryonic genome activation at the eight-cell stage, continuing through the emergence of epiblast

138 nome-wide demethylation is complete at the 2-cell stage, contrary to previous observations in mice.

139 ing and loss of activated STAT5 at the pre-B cell stage corresponds with Igkappa locus accessibility

140 By the early globular ( approximately 32-cell) stage, dcl1-null mutant embryos overexpress approx

141 nalysis of six consecutive neural progenitor cell stages derived from a HES5::eGFP reporter human emb

142 go through a Rag(hi) CD79(+)IgH-mu(+) pre-B cell stage, different from mammals.

143 d that blockade of Erk signalling from the 8-cell stage does not impede blastocyst formation but supp

144 petitive element silencing occurs by the two-cell stage, does not require Xist, and occurs several di

145 oxo1 caused a substantial block at the pro-B cell stage due to a failure to express interleukin 7 rec

146 o-B cells resulted in an arrest at the pre-B cell stage due to lower expression of the recombination-

147 uccessfully fertilized eggs die before the 2-cell stage due to persistence of secreted innate immune

148 tion in nuclear organization occurs at the 8-cell stage during C. elegans embryogenesis.

149 After development into the pro-B cell stage, Ebf1 and other genes switched compartments t

150 ection of DNA constructs into fertilized one-cell stage eggs, followed by a low dose of irradiation,

151 ation is asymmetrically regulated in the two-cell stage embryo and that the PAR-4 and PAR-1 polarity

152 on of polarised blastomeres in the 8- and 16-cell stage embryo determines the fate of daughter cells,

153 ories by analyzing the outwardly similar one-cell stage embryo of its close relative Caenorhabditis b

154 In the eight-cell stage embryo, H3K4me3 deposition is poor in the ger

155 overexpressed in single blastomeres of the 4-cell stage embryo, the progeny of this cell show reducti

156 uring the transition from oocyte to late one-cell stage embryo.

157 a specific cell cycle transition in the one-cell stage embryo.

158 y expressed in the apical membranes of the 8-cell-stage embryo just before morula compaction.

159 advantage of the long cell cycle of the two-cell-stage embryo of the leech Helobdella robusta, we sh

160 n mRNA or proteoglycan/protein core into one-cell stage embryos caused cyclopia.

161 11-33% of 1-cell stage embryos injected with TALEN mRNAs targeting r

162 One-cell stage embryos were injected with NOX4 RNA prior to

163 We discovered that injecting 2-cell stage embryos with a plasmid bearing a varphiC31 in

164 By co-injection of one-cell stage embryos with Cas9 mRNA and Npc1l1 sgRNA, we a

165 n4, whose expression is restricted to late 2-cell stage embryos.

166 ), matured oocytes (metaphase II eggs) and 2-cell stage embryos.

167 ng a guide RNA (gRNA) and Cas9 mRNA into one-cell stage embryos.

168 Blastomeres are removed from morula (eight-cell)-stage embryos and cultured until they form multice

169 either inbred or hybrid ES cells into eight cell-stage embryos efficiently yields F0 generation mice

170 In two-cell-stage embryos harboring abnormal monopolar spindles

171 ine development, matured oocytes (MII) and 8-cell-stage embryos, constituting the ultimate reservoir

172 Satb1 is differentially expressed within 16-cell-stage embryos, with higher expression levels in the

173 antic halibut (Hippoglossus hippoglossus): 2-cell stage (embryos), 1 day-old yolk sac larvae (trunk)

174 mbination with partial blockade at the pro-B cell stage, Emu deletion (core or full length) did not a

175 ced in any position at any time after the 32-cell stage exhibited randomized laterality.

176 ent protein) fusion proteins through the 350 cell stage followed by manual editing.

177 ost severely perturbed at the CD4(+)CD8(+) T-cell stage from which tumors initiate.

178 n encounter at the Rag-expressing immature B-cell stage helps shape pre-immune BCR repertoires.

179 duced and heterogeneously expressed in the 8-cell-stage human embryos during the major wave of embryo

180 logy analysis of genes activated at the four-cell stage identified categories related to RNA processi

181 Beginning at the four-cell stage, imprinted XCI (iXCI) exclusively silences th

182 ac is depleted from the X even before the 30-cell stage in a DCC-independent manner.

183 ry agents to breast cancer cells at a single-cell stage in a laminin-rich ECM (three-dimensional lrEC

184 repetitive elements are silenced at the two-cell stage in a parent-of-origin-specific manner.

185 before B-lineage commitment at the prepro-B cell stage in adult animals.

186 dT RNA is expressed exclusively at the pro-B cell stage in B6.56R.

187 a nearly continuous time scale up to the 350-cell stage in C. elegans embryos.

188 molecular criteria for defining the memory B cell stage in human B cells.

189 t B cell development is blocked at the pre-B cell stage in IFN regulatory factor (IRF)4 (pip) and IRF

190 t B-cell development is blocked at the pre-B-cell stage in mice deficient for Mef2c and Mef2d TFs and

191 B cell development past the pro-B cell stage in mice requires the Cul4-Roc1-DDB1 E3 ubiqui

192 genome activation (ZGA), begins during the 2-cell stage in mouse preimplantation development and mark

193 n is profoundly blocked beyond the pre-pro-B cell stage in Myb(f/f) Mb1-cre mice.

194 arks and germline transcription at the pro-B cell stage in Rag1-deficient mice.

195 ene expression analyses of the pollen mother cell stage in seven diploid sexual and seven diploid apo

196 r earlier in B-cell development at the pro-B-cell stage in the bone marrow.

197 ically at the transitional to naive mature B cell stage in WAS subjects.

198 ntiation, without the requirement of a pre-B cell stage in zebrafish.

199 y GPI, operated mainly at the transitional B cell stages in the spleen, preventing their final differ

200 tablished after the first cell division (two-cell stage) in Caco-2 three-dimensional cultures.

201 ed between multipotent progenitors and Pro-T cell stages included those encoding transcription factor

202 esponse to oxidative stress during red blood cell stages, indicative of a protective role seen in oth

203 rogeneous gene expression, as early as the 4-cell stage, initiates cell-fate decisions by modulating

204 vo polarisation of the mouse embryo at the 8-cell stage is directed by Phospholipase C and Protein ki

205 GL transcription is delayed to the mature B-cell stage is presently unknown.

206 mex-3 3'UTR nor protein degradation at the 4-cell stage is strictly required.

207 of the natural repertoire at the immature B cell stage is sufficient to promote editing.

208 o these two lineages during the 8-cell to 32-cell stages is accompanied by a significant amount of ce

209 Labeling of cells of intermediate, immature cell stages is elevated.

210 at the immature B and double-positive (DP) T cell stages is mediated through tonic (foreign antigen i

211 cell development, but its function at late B cell stages is unknown.

212 atory pattern is determined at the precursor cell stage level.

213 estered at the lamina, and only at the pre-B cell stage located to central nuclear domains.

214 shortly thereafter, at the approximately 300-cell stage, making XND-1 the earliest zygotically expres

215 evels of H3K9 acetylation at the 2-cell to 8-cell stages, meanwhile, significantly decreased the apop

216 sa protein accumulates selectively in the 16-cell stage micromeres, and then is restricted to the sma

217 Moreover, as early as the eight-cell stage, miR156-mediated repression of zygotic SPL tr

218 o investigate whether the blastomeres of two-cell-stage mouse embryos can reprogram more differentiat

219 s to whether individual blastomeres from two-cell-stage mouse embryos have identical developmental pr

220 a human embryo until the approximately eight-cell stage (n=85).

221 ent or -independent) subject to the target T-cell stage of activation and its tissue location.

222 coincides with induction of EBF at the Pro-B cell stage of B cell differentiation.

223 -)VpreB(+)CXCR4(+) Consistent with the pro-B-cell stage of B-cell development, microarray analysis re

224 and E (endoderm) sister cells, born at the 7-cell stage of C. elegans embryogenesis.

225 g globin in the liver occurs at a progenitor cell stage of development and is preceded by DNA replica

226 However, cells at the pre-B-cell stage of development did not initiate disease.

227 o a partial developmental block at the pre-B cell stage of development.

228 and is necessary for cleavage beyond the two-cell stage of development.

229 The C. elegans MS blastomere, born at the 7-cell stage of embryogenesis, generates primarily mesoder

230 paternal X chromosome (Xp) at about the four-cell stage of embryonic development.

231 ants of the progenitor MS, born at the seven-cell stage of embryonic development.

232 on of RNA Pol II at Ser2 observed at 2- or 4-cell stage of embryos under Padi1 knockdown or inhibitin

233 bryos, is symmetrically localized in the one-cell stage of Protorhabditis group species.

234 rosomes for all cell sizes down to the eight-cell stage of the Caenorhabditis elegans embryo, and it

235 and VEGF120 mice at E9.5, the primitive stem cell stage of the neuroepithelium.

236 against the asexually reproducing red blood cell stages of the parasite, which are responsible for t

237 scent Gata6 and Nanog protein from the eight-cell stage onward before it preferentially cosegregates

238 the CFU-E/proerythroblast (CD71(+) Ter119(-) cells) stage onward, erythroid progenitors exhibited exc

239 PK is not required in 3D later during the 24-cell stage or in the embryonic organizer, 4d, for its no

240 to affect zygotic gene activation at the two-cell stage or lineage gene transcription at the morula s

241 The highly correlated gene pairs at the 4-cell stage overlapped with those showing the same direct

242 es that proliferation during pro-B and pre-B cell stages plays an important role in the homeostasis o

243 embryos are preimplantation lethal by the 32-cell stage, precluding in vivo study of Geminin's role i

244 intact IL-7 signaling, GON4L-deficient pro-B cell stage precursors failed to undergo a characteristic

245 ell development is blocked at the immature B cell stage, produce diverse H chain-only antibodies in s

246 d to the future organizer region by the four-cell stage, providing the earliest evidence of embryonic

247 ary to expectations, outside cells at the 16-cell stage represent a heterogeneous population, with so

248 After the 4-cell stage, residual MEX-3 is degraded in somatic cells,

249 r 4 h to edit the lineage to the 194- or 350-cell stage, respectively.

250 rexpression and knockdown of Dvr1 at the one-cell stage resulted in defects at epiboly and C&E.

251 ete block in B cell development at the pre-B cell stage resulting from a deletion in the Fnip1 gene.

252 transporters are affected as early as the 8 cell stage, resulting in apical redistribution of auxin.

253 ells was impaired at the pre- and immature B cell stage, resulting in decreased numbers of follicular

254 Deletion of Cdc42 from proB/preB-cell stage significantly blocked B-cell development at T

255 ion and chromatin modification underlies the cell stage-specific mechanism of MOR gene expression.

256 be differentiated to hematopoietic precursor cells, stage-specific analysis of T cell maturation conf

257 ome of the polarization events at the late 8-cell stage such as compaction and apical localization of

258 cell stage, TET3 mRNA remained high at the 4-cell stage suggesting that degradation of TET3 is relate

259 GCB cell to the plasmablast--the transient B-cell stage targeted in ABC-DLBCL transformation--by anta

260 minor differences were detected in the pro-B cell stage tended to diminish with B cell maturation, su

261 cription or translation was blocked at the 2-cell stage, TET3 mRNA remained high at the 4-cell stage

262 opment is arrested at an IgD- transitional B cell stage that we term transitional type 0 (T0).

263 g been known that one blastomere at the four-cell stage, the D cell, and its direct descendants play

264 uses a reduction in SKN-1 asymmetry at the 2-cell stage, the function of eel-1 in both the spatial an

265 During its red blood cell stage, the malaria parasite Plasmodium falciparum c

266 al distribution was lost, such that by the 2-cell stage there was no evidence of PKA localisation.

267 also execute the chiral skew event at the 4-cell stage to establish the C. elegans LR body axis.

268 dynamics of mouse development from the eight-cell stage to postimplantation using lineage-specific RN

269 sis at the transition from the large pre-BII cell stage to the small pre-BII cell stage was exacerbat

270 ifferent cell stages (1-, 2-, 4-, 8-, and 16-cell stage) to investigate the localization changes of s

271 nscriptionally inactive, but at around eight-cell stage transcription is activated in the somatic lin

272 ur understanding of the parasite's red blood cell-stage transcriptome.

273 MAPK is activated in 3D just prior to the 24-cell stage, transiently in 4d and finally in a subset of

274 mbryo development was also arrested at the 4-cell stage upon depletion of PADI1 or inhibition of PADI

275 We find that at the 16-cell stage, very few inside cells are initially produced

276 arge pre-BII cell stage to the small pre-BII cell stage was exacerbated by abnormal cytokine signalin

277 To induce deletion of podoplanin at the 2-cell stage, we generated a podoplanin(fl/fl) mouse cross

278 iological pathways related to the three germ cell stages were constructed.

279 When blastomeres of 4- to 8-cell stages were dissociated, the polarized MOEP19 domai

280 Embryos (1-4 cell stage) were microinjected with either 1 or 10 ng ve

281 s asymmetry becomes more pronounced at the 4-cell stage, when SKN-1 is high in the posterior cell's d

282 have a developmental block at the pro/pre-B cell stage, whereas a B cell-specific Shp-1 deficiency p

283 to progress toward the transitional type 2 B cell stage, whereas cells that have passed this step gen

284 or developmental progression at the prepro-B cell stage, whereas E12 is dispensable for early B cell

285 observed in all euploid embryos to the four-cell stage, whereas only 30% of aneuploid embryos exhibi

286 n of monocytes and LCs at an early precursor cell stage, whereas progenitor cell expansion or granulo

287 the H chain locus is accessible at the pro-B cell stage, whereas the L chain loci become accessible a

288 4d is a predominant transcript at the late 2-cell stage, whereas Zscan4c is a predominant transcript

289 lamina to central domains only at the pro-B cell stage, whereas, Igkappa remained sequestered at the

290 negative) to CD4(+)CD8(+) (double positive) cell stages, whereas T cell activation and adhesion are

291 ent at a very early embryonic stage, the six-cell stage, which also establishes the L/R asymmetric pl

292 lei of the four vegetal-most cells at the 64-cell stage, which give rise to definitive larval and adu

293 and multiple progenitor (transit-amplifying) cell stages, which ultimately give rise to TD cells.

294 mbryos were arrested in metaphase at the two-cell stage with high levels of cyclin B1, indicating an

295 sulted in a developmental block at the pre-B cell stage, with a corresponding lack of peripheral B ce

296 mice results in embryonic arrest at the 1-2 cell stage, with arrested embryos failing to undergo the

297 gregation of chromosomes as early as the two-cell stage, with corresponding high levels of aneuploidy

298 BAergic and glutamatergic neurons for the 32-cell stage Xenopus embryo with the goal of determining w

299 progression of the nervous system for the 32-cell stage Xenopus embryo.

300 ection of mRNAs encoding these ZFNs into one-cell-stage zebrafish embryos led to mutagenic lesions at