ライフサイエンスコーパス: cell surface

1 wo proteins if they bind in proximity on the cell surface.

2 AMPA glutamate receptors to the postsynaptic cell surface.

3 d by all three proprotein convertases at the cell surface.

4 ately determines the number of AMPARs on the cell surface.

5 aICP0 mutant virus, Nectin-1 remained on the cell surface.

6 e array of carbohydrate presentations on the cell surface.

7 proteins as periodic traveling waves on the cell surface.

8 2 nAChR was preferentially trafficked to the cell surface.

9 ds of the UL16 binding protein family on the cell surface.

10 ferent angles between the phage tail and the cell surface.

11 onversion of plasminogen into plasmin on the cell surface.

12 ly interact and form dimers expressed at the cell surface.

13 n and nuclear reprogramming by acting at the cell surface.

14 d that IFN-beta interacts with the bacterial cell surface.

15 by limiting the amount of Env present at the cell surface.

16 is facilitated by bacterial adhesins at the cell surface.

17 genome enters cells only after fusion at the cell surface.

18 ne (FAZ), which adheres the flagellum to the cell surface.

19 UNC5A from the endoplasmic reticulum to the cell surface.

20 nces their trafficking and expression on the cell surface.

21 signaling by removing Wnt receptors from the cell surface.

22 re elaborate structures that extend from the cell surface.

23 restoring filament formation at the infected-cell surface.

24 ated via the alternative pathway (AP) on the cell surface.

25 and a complementary enzyme expressed on the cell surface.

26 icantly inhibited toxin association with the cell surface.

27 tion of MHC class I-epitope complexes at the cell surface.

28 activity and increased exposure of PS on the cell surface.

29 cells, and it colocalizes with mCD22 on the cell surface.

30 y blocking the translocation of GLUT4 to the cell surface.

31 mic reticulum), whereas KCNE1 resides on the cell surface.

32 is bound in the extracellular matrix on the cell surface.

33 ulates NCAM functions of neural cells at the cell surface.

34 different settings through exposition at the cell-surface.

35 he quantities of binding of these viruses to cell surfaces.

36 ctural biology to render and analyze complex cell surfaces.

37 arin increased the amount of hIL-12 bound to cell surfaces.

38 lly bound to and entered EREC at basolateral cell surfaces.

39 latelets were used in vivo to remodel target cell surfaces.

40 stribution of adhesive properties on rolling cell surfaces.

41 than potential nucleation sites provided by cell-surfaces.

42 ubiquitination, which ultimately change the cell surface accumulation of Smo.

43 id pH-dependent proteases rather than on the cell surface acid pH-independent serine protease TMPRSS2

44 The up-regulation of cell surface adhesion molecules by BMP9/10 in the presen

45 egrin function and trafficking.Integrins are cell-surface adhesion receptors that are modulated by en

46 s, hexamer formation, and CDC after Ab binds cell-surface Ag.

47 ciple, invoke this tolerogenic mechanism for cell surface Ags.

48 ns (Env) are expressed and accumulate on the cell surface, allowing infected cells to be detected and

49 ose the intracellular protein content on the cell surface, allowing T cells to detect foreign or muta

50 dence from one strain has uncovered a unique cell surface 'amylosome' complex that organizes starch-d

51 of interactions in bio-molecular studies and cell-surface analysis without the need for labeling proc

52 plexed proteomics approach to quantify 1300 cell surface and 7200 whole cell proteins, we demonstra

53 ult in redistribution of phospholipid at the cell surface and actomyosin in the cortex.

54 nder basal conditions but can traffic to the cell surface and boost the IKs amplitude in response to

55 lves the use of chemokine receptors on the T-cell surface and chemokines that are present in infected

56 absence of Atthog, SMO was stabilized at the cell surface and concentrated in the ciliary membrane, b

57 Curli is assembled at the cell surface and consists of CsgA, the major subunit of

58 ization of a receptor tyrosine kinase at the cell surface and directly measure binding and dissociati

59 PLA2R co-localised with S100A10 at the cell surface and in extracellular vesicles.

60 docytic adaptor proteins bind cargoes at the cell surface and link them to the PM and clathrin coat.

61 that products of both genes are found at the cell surface and released into media.

62 microtubules (MTs) as a conduit to reach the cell surface and restricted MT-mediated Cx43 delivery to

63 target of multiple processing events on the cell surface and these were characterised using an N-ter

64 ce secreted, associates with the ECM and the cell surface and tightly controls the bidirectional flow

65 eir work reminds us of the fractal nature of cell surfaces and highlights how the unfolding of these

66 amer can also be used to distinguish between cell-surface and internalized EGFR on the basis of the a

67 An 'interactome' screen of all Drosophila cell-surface and secreted proteins containing immunoglob

68 ion of adhesion molecules on the endothelial cell surface, and decreased endothelial barrier integrit

69 evels of ZnT8 expression, its display on the cell surface, and glucose-stimulated insulin secretion (

70 human fibroblasts express vimentin on their cell surface, and MS analysis revealed a posttranslation

71 tibodies against one or more of the neuronal cell surface antibodies compared with four (4%) of 105 c

72 uced maturation protein-1 (BLIMP-1), and the cell surface antigens CD38 and CD138/Syndecan-1.

73 bodies that recognized senescence-associated cell-surface antigens by FACS analysis and a newly devel

74 accompanied by an apparent large increase in cell surface area, the nature of the membrane "reservoir

75 differences between the estimated and actual cell surface area.

76 is site but subsequently moves away from the cell surface as it stimulates Arp2/3 complex to assemble

77 spd, nga [spn], prtS [SpyCEP], and sse) and cell surface-associated factors of GAS (emm1, mur1.2, si

78 re the interplay between the AutoAbs against cell surface-associated GRP78, TF expression/activity, a

79 duced ectoderm, cortical tension of the free cell surfaces at gaps does not return to the high values

80 ed between adjacent cells, and curvatures of cell surfaces at gaps.

81 d the mechanisms regulating its activity and cell surface availability also remain enigmatic.

82 llular matrix (ECM) protein cochlin with the cell surface bound and stretch-activated channel TREK-1.

83 these low-affinity anti-IgE mAbs bind to the cell surface-bound IgE without triggering anaphylactic d

84 prevented the transport of CRF2betaR to the cell surface but had no effect on CRF1R.

85 equent insulin secretion exposes ZnT8 to the cell surface, but the humoral antigenicity of the surfac

86 Full-length uPAR is released from the cell surface, but the mechanism and significance of uPAR

87 action prevents the translocation of pMHC to cell surface by causing the accumulation of pMHC inside

88 8-10 amino acids long, are presented at the cell surface by major histocompatibility complex (MHC) c

89 ells by binding to peptides presented on the cell surface by MHC class I molecules.

90 othesis that CLCA1 stabilizes TMEM16A at the cell surface by preventing its internalization.

91 eport that FAF1 destabilizes TbetaRII on the cell surface by recruiting the VCP/E3 ligase complex, th

92 related ATPase that confines caveolae to the cell surface by restricting the scission and subsequent

93 on between miR-34a and gammaSI increased the cell surface calreticulin (CRT) expression, that is well

94 e here that disruption of FH function on the cell surface can also lead to disseminated complement-de

95 central to our understanding of the roles of cell-surface carbohydrates (the glycocalyx), fundamental

96 ver that is essential for recycling numerous cell-surface cargoes from endosomes and is structurally

97 1.0E(-6)) and with lower diagnostic leukemic cell surface CD33 intensity ( P < 1.0E(-6)).

98 itance) through (i) polarization of captured cell-surface charges, (ii) cells' internal bioactivity,

99 egradation of collagen film, suggesting that cell-surface collagen degradation by MT1-MMP involves DD

100 h of these phenotypes via CD55, an intrinsic cell surface complement inhibitor, which was identified

101 ins from the plasma membrane (PM) allows for cell-surface composition regulation, signaling of networ

102 Cell surface connexons dock between adjacent cells to al

103 ly identify a continuous F-actin ring at the cell surface constriction in mouse erythroblasts, nor at

104 organoid self-organization requires cell-to-cell surface contact.

105 The Staphylococcus aureus cell surface contains cell wall-anchored proteins such a

106 oreover, high FZD receptor expression at the cell surface contributes to overactive Wnt signaling in

107 GABAAR pentamers in hippocampal slices using cell-surface cross-linking, followed by Western blot and

108 Therefore, the abundance of Kv1.3 at the cell surface decreases, which is clearly compatible with

109 orylation signals may differentially control cell surface density of GPR15 through endocytosis.

110 a persistent pool of GPRC6A receptors at the cell surface despite chronic agonist exposure.

111 We use yeast cell surface display to engineer E6AP to exclusively tra

112 cytotoxicity (ADCC) assays revealed that the cell surface DPP4 preferentially sensitized senescent, b

113 ase (MT1-MMP) and EGF receptor (EGFR) to the cell surface during invadopodium formation.

114 agonist-mediated reduction of the density of cell surface endogenously expressed CB1Rs was clathrin a

115 Cell surface engineering is an expanding field and whils

116 The cell-surface engineering methodology can easily be adapt

117 antibodies have the potential to bind HIV-1 cell surface Env and promote elimination of infected CD4

118 otein CD230/PrP(C) and the immunosuppressive cell surface enzyme ecto-5'-nucleotidase CD73.

119 -coreceptor complexes triggers non-apoptotic cell surface exposure of the membrane lipid phosphatidyl

120 trate that these 'ecto-tagged' integrins are cell-surface expressed, localize to adhesions, exhibit n

121 f GABAB receptors (GABABRs) to control their cell surface expression and intracellular trafficking vi

122 5 gene as well as promoter region that alter cell surface expression have been associated with diseas

123 We observed preferential cell surface expression of CCR10 and CXCR3 by HSV-specif

124 ) T cells by creating conditions that induce cell surface expression of CD39, an immunosuppressive mo

125 ling during development by the modulation of cell surface expression of Fz receptor.

126 Additionally, cell surface expression of the CML stem cell markers CD2

127 US18 and US20 work in concert to suppress cell surface expression of the critical NKp30 ligand B7-

128 ntaining a mutant gamma2 subunit had reduced cell surface expression with altered subunit stoichiomet

129 presses NF-kappaB activation and reduces CD4 cell surface expression.

130 rmore RAP alone produced a small increase in cell-surface expression of CaV2.2, alpha2delta-1 and the

131 ler (NK) cells as defined by accumulation of cell-surface expression of CD57 is associated with incre

132 Here, we demonstrate that cell-surface expression of endogenous Notch1 in HEK293T

133 Macrophage subpopulation cell-surface expression of immunological markers and pha

134 ular filtration rate but alter the total and cell-surface expression of major Na(+) transporters all

135 enes and showed that 1,25D treatment induces cell-surface expression of PD-L1 in epithelial and myelo

136 ER export is not sufficient to enable normal cell-surface expression of TREM2.

137 h TGFbeta or undergoing EMT upregulated CD73 cell-surface expression, confirming roles for these path

138 GPI anchoring of CaValpha2delta1 averts its cell-surface expression, its interaction with CaValpha1,

139 the Golgi complex and show markedly reduced cell-surface expression.

140 Autotransporter proteins are a class of cell-surface factor used by E. coli for adherence.

141 ants G1060I and G1061I nearly eliminated the cell-surface fluorescence of CaValpha2delta1, indicated

142 fficking of GluA2-containing AMPARs from the cell surface, followed by a delayed reduction in GluA2 m

143 r TarGH, which exports WTA precursors to the cell surface for attachment to peptidoglycan.

144 Palmitoylated Wnt ligands engage cell-surface frizzled (FZD) receptors and LRP5 and LRP6

145 Chemokines and their cell surface G protein-coupled receptors are critical fo

146 a membrane (PM), where they are activated by cell surface G protein-coupled receptors.

147 try of rhesus rotavirus, VP8* interacts with cell surface gangliosides, allowing engulfment into a me

148 ated gene-centered Y1H screens using a novel cell surface Gaussia luciferase reporter.

149 t 10% of the added particles attached to the cell surface, giving an overall ratio of added particles

150 While HIP1 was required for the coupling of cell surface GLP-1R activation with clathrin-dependent e

151 antibody that binds carbonic anhydrase IX, a cell surface glycoprotein ubiquitously expressed in clea

152 hanges in GNE activity can alter affinity of cell-surface glycoproteins for the galectin lattice.

153 corporated into O-GlcNAcylated proteins over cell-surface glycoproteins.

154 on of cell adhesion molecules and an altered cell surface glycoproteome.

155 molecular mechanism in which AutoAbs against cell-surface GRP78 drive TF-mediated tumor progression i

156 nstrate that these anti-GRP78 AutoAbs target cell-surface GRP78, activating the unfolded protein resp

157 addition of heparin or enzymatic removal of cell surface heparan sulfates.

158 inding data support a notion that changes in cell surface HS composition can modulate protein functio

159 e examined the role of syndecan-1, the major cell-surface HSPG of hepatocytes, in AILI.

160 s, perception of invading pathogens involves cell-surface immune receptor kinases.

161 t GABABR activation can regulate KCC2 at the cell surface in a manner that alters intracellular chlor

162 g a failure to express their products at the cell surface in association with the BCR H chain.

163 or (BCR) classes, which are organized on the cell surface in distinct protein islands.

164 echanisms to study the mechanobiology of the cell surface in other cell types, including animal cells

165 retained wild-type function localizes to the cell surface in response to low hemin concentrations, bu

166 ported to undergo biochemical changes at the cell surface in response to treatment with lysophosphati

167 of vascular endothelial (VE)-cadherin at the cell surface in these blood vessels.

168 C. lytica that the vesicles are budded from cell surfaces in a manner consistent with the production

169 ey become engulfed following attachment to a cell surface, in order to gain access to the cell interi

170 interacts with and anchors E-cadherin to the cell surface independent of NCX1 ion transport activity.

171 und proteoglycans increases with distance to cell surface, indicating reduced confinement by neighbor

172 iously we found that CD11d overexpression on cell surfaces inhibits in vitro cell migration due to ex

173 es of live yeast and mammalian cells through cell surface-initiated controlled radical polymerization

174 D33M, the CD33m isoform does not localize to cell surfaces; instead, it accumulates in peroxisomes.

175 nstrate that intracellular forces can orient cell surface integrins and support a molecular model of

176 ies, because of the constitution of specific cell-surface interactions.

177 We find that, in response to TGF-beta, cell surface-internalized FN is not degraded by the lyso

178 agm, and proper expression of nephrin on the cell surface is critical to ensure integrity of the bloo

179 te that the dominant form of TMPRSS13 on the cell surface is phosphorylated, whereas intracellular TM

180 Quantifying the glycan expression status on cell surfaces is of vital importance for insight into th

181 Cell-surface labeling experiments indicate that the domi

182 We also find that receptor cell surface levels increase following acute GSK3beta in

183 Compared with wild-type mice, the cell surface levels of Cav1.2 in the brain, as well as C

184 revealed that, within 15 min, NEM increased cell surface levels of KCC2 and modulated the phosphoryl

185 ncreased trans-cellular binding and elevated cell-surface levels due to reduced endocytosis.

186 ha4betagamma2 subtypes, as well as increased cell-surface levels of GABAAR alpha2 and gamma1 subunits

187 cancer cells and infected cells by engaging cell surface ligands that are induced preferentially or

188 hether exogenously added gangliosides (i.e., cell surface lipids with a potential to modulate signali

189 main restored proper protein trafficking and cell surface localization of multiple biosynthetic mutan

190 Loss-of-function mutations in SLC30A10, a cell-surface-localized manganese efflux transporter, cau

191 on to the UF membrane surface is mediated by cell-surface macromolecules (likely to be outer membrane

192 mour immunity is attributed to an absence of cell surface major histocompatibility complex (MHC)-I mo

193 olobus purpureas agglutinin (TPA) as a novel cell surface marker that allows for such delineation.

194 thelial cells expressed specific endothelial cell surface markers and also exhibited the capacity for

195 Existing cell surface markers for GSC are developed from embryoni

196 n is reliant on the presence of well-defined cell surface markers specific for diverse progenitor pop

197 ly carried out by quantification of multiple cell surface markers, transcription factors and cytokine

198 lliliter of blood and the fold expression of cell surface markers.

199 human fetal pancreatic differentiation using cell surface markers.

200 on and the number of channel proteins on the cell surface membrane.

201 Cell surface molecular adhesions govern many important p

202 The cell surface molecule, integrin alphavbeta3, is activate

203 ificity, with several ubiquitously expressed cell surface molecules playing a role in VSV attachment

204 However, it is unclear whether other cell surface molecules serve as coregulators of EMS1.

205 We reveal a combinatorial code of TFs, cell surface molecules, and determinants of neuronal mor

206 the mouse uterus and found that they express cell surface molecules, including the IL-33 receptor, ST

207 Transcription factors and cell-surface molecules are the most differentially expre

208 ipeline to discover differentially expressed cell-surface molecules in neuroblastoma that meet criter

209 in production of many different soluble and cell-surface molecules that signal to cells of the immun

210 mulation of lipid bodies, and alterations of cell-surface morphology.

211 GFR and increased the abundance of total and cell-surface NHE3, NKCC2, NCC, alpha-ENaC and cleaved ga

212 bserved increased endoglin expression on the cell surface of an HCV core-expressing hepatocellular ca

213 linTT1, p32 (or gC1qR), is expressed on the cell surface of peritoneal carcinoma cell lines of gastr

214 s, which are constitutively expressed on the cell surface of the allograft endothelium, autoantigens

215 into PrP(Sc) is thought to take place at the cell surface or in endolysosomal organelles.

216 related proteins expressed on the vegetative cell surface or spore coat of C. difficile These include

217 The WDR4/PML axis induces a set of cell-surface or secreted factors, including CD73, urokin

218 increases their biophysical association with cell surfaces over very short time periods under convect

219 The underlying mechanism requires a direct, cell surface, planar polarised cue, which we posit depen

220 y conserved protective antigens that include cell surface polysaccharides and cell-associated and cel

221 Shisa2, which inhibits the glycosylation and cell surface presentation of Frizzled3 in rodent commiss

222 ication involve the protrusion of actin-rich cell surface projections such as lamellipodia and filopo

223 rthermore, artificial polysialylation of the cell surface promotes oligodendrocyte differentiation.

224 including the interleukin-6 receptor (IL6R), cell surface protease inhibitor Spint-1, the collagen re

225 , a putative adhesion molecule, and HAI-2, a cell surface protease inhibitor.

226 ndicate that Reck and Gpr124 are part of the cell surface protein complex that transduces Wnt7a- and

227 Here, we demonstrate that the cell-surface protein CD276/B7-H3 is broadly overexpresse

228 g immunoglobulin-like lectin (Siglec)-8 is a cell-surface protein expressed selectively on human eosi

229 s not provide phenotypic information such as cell-surface protein levels.

230 he vertebrate clustered protocadherin (Pcdh) cell surface proteins are encoded by three closely linke

231 Two interacting pairs of cell surface proteins independently promote fasciculatio

232 Plasmodium vivax, rely on two distinct host cell surface proteins, CD81 and the Scavenger Receptor B

233 so collate a set of AS and DE genes encoding cell surface proteins, which present promising diagnosti

234 of IL-4 and analyzed for expression of >300 cell-surface proteins.

235 ey affect growth by enhancing the ability of cell surface proteoglycan glypican-1 to act as a co-rece

236 -NODAGA-PSMA-Mb retained the ability to bind cell surface PSMA, and both radiotracers exhibited selec

237 et al. (2017) identify neuropilin (NRP)-2 as cell surface receptor and the tetraspannin protein CD63

238 The cell surface receptor CD6 regulates T cell activation in

239 MDSCs were phenotyped for cell surface receptor expression and enriched by cell so

240 CTLA4 is a cell surface receptor on T cells that functions as an im

241 lutinin (HA) and neuraminidase (NA) with the cell surface receptor sialic acid.

242 nly cells that express the cognate chemokine cell surface receptor, migrate under the spot containing

243 ells that differentially produce the alphaDG cell surface receptor.

244 llular prion protein (PrP(C)) functions as a cell-surface receptor, which binds to Abeta oligomers an

245 (GPs) mainly engage alpha-dystroglycan as a cell-surface receptor, while New World arenaviruses hija

246 cules derived from microbes are perceived by cell surface receptors and upon signaling to the nucleus

247 ions between the Fc region and two principal cell surface receptors FcepsilonRI and CD23.

248 Not much is known about which cell surface receptors may be involved in the cell-to-ce

249 Several cell surface receptors that participate in B. burgdorfer

250 med after the secreted proteins that bind to cell surface receptors to activate the pathway, plays cr

251 Here we show that Sema7A utilizes different cell surface receptors to control the proliferation and

252 hether and how APP may regulate functions of cell surface receptors, including GPCRs, remains largely

253 Following attachment to cell surface receptors, reovirus is internalized by rece

254 sulting from the reliance of HCV on multiple cell surface receptors, suggesting that vaccine inductio

255 Cell surface receptors, transcription factors, and the t

256 ens stems from the broad diversity of immune cell surface receptors.

257 hat directly target neutrophils via specific cell surface receptors.

258 an be mobilized in response to activation of cell surface receptors.

259 and activation via signaling through various cell surface receptors.

260 ugh Rab5 GTPases that control endocytosis of cell-surface receptors and Abl nonreceptor tyrosine kina

261 Cell-surface receptors and their ligands have traditiona

262 no known host cell receptors for TcdA, three cell-surface receptors for TcdB have been identified: CS

263 -coupled receptors (GPCRs), a superfamily of cell-surface receptors involved in virtually all physiol

264 Stimulation of cell-surface receptors that couple to phospholipase C to

265 iew is that SRC acts primarily downstream of cell-surface receptors to control intracellular signalin

266 A diverse group of cell-surface receptors, including many G protein-coupled

267 es, indicating that eNAD(+) may be sensed by cell-surface receptors.

268 GNE activity might affect signaling through cell-surface receptors.

269 ellular membranes, may play a role in target-cell surface recognition or stabilization of the heptame

270 tin-3-binding molecule(s) on the endothelial cell surface responsible for the galectin-3-mediated cyt

271 he biorecognition of complementary motifs at cell surface resulting in receptor crosslinking and apop

272 Depletion of cell surface Sia by neuraminidase treatment inhibited ME

273 thogenic bacteria have evolved sophisticated cell surface signaling and transport systems to obtain h

274 ed deltaR from the Golgi and delivery to the cell surface, similar to treatment with nerve growth fac

275 deed, insertion of CD22 ligands into the RBC cell surface strongly inhibited B cell activation, cytok

276 DC-SIGN is a dendritic cell surface structure which participates in binding and

277 ed biosensor or a system that guarantees the cell surface targeting of the heterodimer only.

278 has a recycling route from endosomes to the cell surface that functions efficiently after inactivati

279 rient-rich organic particles for a non-stick cell surface that helps them evade predation by mucous f

280 oplasmic reticulum redox protein folding and cell-surface thiol-redox control of thrombosis and vascu

281 e potent vaccine adjuvants, interacting with cell surface TLR2 heterodimers.

282 e ranging from approximately 150 nm near the cell surface to approximately 400 nm near the cell edge.

283 ly one expects an AFM tip interacting with a cell surface to be repelled due to cell elastic distorti

284 ronic stress, KCNQ1 traffics from jSR to the cell surface to boost the IKs amplitude in a process dep

285 in-containing protein that traps EGFR at the cell surface to facilitate its activation by EGF.

286 contiguous dynamic membrane processes on the cell surface to function as a stable signaling apparatus

287 somal proteins, but traffic rapidly from the cell surface to lysosomes and have a half-life of less t

288 rapid hemin-induced internalization from the cell surface to the vacuolar membrane and that the trans

289 through O2 production, the capacity of their cell surfaces to sorb iron, and the interaction of secre

290 of each integrin conformational state on the cell surface, together with the length scales of conform

291 One proposal is that the wrinkled cell surface topography (which forms micro-ridges on the

292 is approach provides clear evidence that the cell surface topography changes dramatically during neut

293 Catabolic remodelling of the cell surface trehalose mycolates of M. tuberculosis spec

294 Thus, by restraining TNFR1 at the cell surface via sialylation, ST6Gal-I acts as a functio

295 3D-MTC, ferromagnetic beads are bound to the cell surface via surface receptors, followed by their ma

296 g HAdV5 to a baculovirus, which binds to the cell surface via the envelope glycoprotein Gp64.

297 TMEM16A protein levels on the cell surface were increased in HEK293T cells transfected

298 osits, we show that functionalization of the cell surface with LBT yielded several notable advantages

299 nsive research has been performed decorating cell surfaces with biomolecules, the engineering of cell

300 rfaces with biomolecules, the engineering of cell surfaces with particles has been a largely unexploi