ライフサイエンスコーパス: cell-autonomous

1 ression, indicating that glial pathology was cell autonomous.

2 roximal neurons, most E46K aSyn toxicity was cell autonomous.

3 muscular or vascular structures is entirely cell autonomous.

4 t caused by premature differentiation and is cell-autonomous.

5 lude that hypoglycemia in SCHAD-CHI is islet cell-autonomous.

6 riants in D. melanogaster nephrocytes caused cell-autonomous accumulation of the endocytic tracer atr

7 this process involves the interplay between cell-autonomous actin-generated pushing forces in the em

8 of the first demonstrations of postsynaptic, cell-autonomous actions of endocannabinoids in the mamma

9 in target pacemakers with long durations by cell-autonomous actions.

10 cells in a paracrine manner, in part by non-cell autonomous activation of the GLI transcription fact

11 We report that loss of HVEM leads to cell-autonomous activation of B cell proliferation and d

12 Tumor-specific and cell-autonomous activation of the tumorigenic JNK stress

13 re, we report the consequences of prolonged, cell-autonomous activation of the UPR(MT) in C. elegans

14 ational image analysis distinguishes between cell-autonomous (active) displacements and convection ca

15 varied roles of Notch in cancer, focusing on cell autonomous activities that may be either oncogenic

16 MPK) alpha1-catalytic subunit, which governs cell-autonomous adaptations during metabolic stress.

17 Here we demonstrate the acute and specific cell-autonomous addiction of KRAS-mutant non-small-cell

18 H2AX knockout mice showed cell-autonomous anaemia and erythroid dysplasia, mimicki

19 We show that BDNF acts cell autonomous and autocrine, as wildtype neurons are n

20 Evidence for Y4-mediated carcinoma cell autonomous and immune-dependent cytotoxicity is pre

21 ectal cancer development and progression via cell autonomous and microenvironmental effects.

22 These findings suggest that there are both cell autonomous and non-cell-autonomous defects in SMA m

23 ased IMQ-induced keratinocyte death via both cell autonomous and noncell autonomous mechanisms.

24 Induction of cell death was cell autonomous and required RNA synthesis but not viral

25 nus leads to neuronal degeneration both in a cell-autonomous and a non-cell-autonomous manner.

26 RA acts upstream of the WNT pathway via non-cell-autonomous and cell-autonomous mechanisms to ensure

27 ulator of brain vascular development via non-cell-autonomous and cell-autonomous regulation of endoth

28 How cell-autonomous and circuit-level mechanisms interact in

29 rk toward its limits and, by doing so, probe cell-autonomous and emergent, circuit-level properties.

30 in Drosophila elucidate the contribution of cell-autonomous and endocrine mechanisms to the establis

31 s in reduced wound and tumor angiogenesis by cell-autonomous and extrinsic mechanisms.

32 ude the choice of immunoglobulin class, both cell-autonomous and extrinsic metabolic programming have

33 s well as preclinical evidence of both tumor cell-autonomous and immune-mediated effects.

34 sfunction in macrophages in a manner that is cell-autonomous and independent of infectious triggers.

35 or suppressor loss in Schwann cells triggers cell-autonomous and intercellular changes, resulting in

36 The Fng tKO phenotype was cell-autonomous and largely rescued in mice expressing o

37 ctional diversity that is initiated early by cell-autonomous and local environmental factors found wi

38 reveals acute, protein-specific induction of cell-autonomous and network-level circadian rhythmicity

39 ve 2-methoxyestradiol (2-ME2) disrupted both cell-autonomous and non-cell-autonomous pathways.

40 alian stress response, and functions in both cell-autonomous and non-cell-autonomous ways to promote

41 y manipulation in a tumor cell can have both cell-autonomous and nonautonomous effects and suggest th

42 ing that NSML-associated mutations have both cell-autonomous and nonautonomous functions in cardiac d

43 RTN neurons encode arterial PCO2 /pH via cell-autonomous and paracrine mechanisms, and via input

44 tions to accelerate leukaemogenesis, through cell-autonomous and possibly non-cell-autonomous mechani

45 nces in optic glioma phenotypes reflect both cell-autonomous and stromal effects of the germline Nf1

46 norhabditis elegans to mammals have revealed cell-autonomous and systemic DDR mechanisms that orchest

47 on in multicellular organisms relies on both cell-autonomous and systemic immunity.

48 vation showed a distinct profile between the cell-autonomous and the medium-transfer experiments.

49 type of Smo inhibition is haploinsufficient, cell autonomous, and correlates with the accumulation of

50 Cell-autonomous antagonism between these pathways enable

51 ew studies indicate that, in addition to its cell-autonomous anti-tumorigenic functions, autophagy in

52 We show that Rab32 represents a general cell-autonomous, antimicrobial defense that is counterac

53 mall interfering RNAs are at the vanguard of cell-autonomous antiviral immunity.

54 Although STING is redundant for cell-autonomous antiviral resistance in astrocytes and n

55 ositive thymocytes, they underwent increased cell-autonomous apoptosis in vitro and displayed a short

56 cytes, we demonstrated intracellular and non-cell-autonomous apoptotic growth inhibition of tumor cel

57 , we systematically investigated the role of cell-autonomous AR in different prostate epithelial cell

58 e regressed prostate only in the presence of cell-autonomous AR, supporting a facultative model for C

59 sults strongly suggest that hSef-b acts in a cell autonomous as well as non-cell autonomous manner.

60 iferation of Grb14-deficient hepatocytes was cell-autonomous as it was also observed in primary cell

61 nt is lethal in Drosophila This lethality is cell-autonomous, as directed expression of the mutant Fi

62 Cell-autonomous asymmetry is not explained by current mo

63 elanogaster malignant tumour model, that non-cell-autonomous autophagy is induced both in the tumour

64 Cell-autonomous B-cell receptor (BcR)-mediated signallin

65 The cell-autonomous beneficial component of NR treatment was

66 The circadian clock, an endogenous and cell-autonomous biological timekeeper that produces rhyt

67 remodeling of the stromal ECM to promote non-cell autonomous breast tumor progression.

68 These results suggest that cell autonomous changes in both neurons and glia may con

69 ntegration may result from LTP but also from cell-autonomous changes in membrane excitability.

70 could be accounted for, at least in part, by cell-autonomous changes in the functional development of

71 bone marrow microenvironment, demonstrating cell-autonomous changes in the MPP compartment with agin

72 on, metabolism is also tightly controlled by cell-autonomous circadian clock.

73 Cell-autonomous circadian clocks interact with daily lig

74 em (SAM) that translates perception of a non-cell-autonomous CLAVATA3 (CLV3) peptide signal into alte

75 here that this mechanism is mediated not via cell-autonomous clock properties, but rather through alt

76 These cell-autonomous clocks are composed of a transcription-t

77 This work shows that cell-autonomous co-ordination of cell growth and cell di

78 Although we identified a minor non-cell-autonomous component spatially restricted to proxim

79 neurodegeneration caused by Munc18-1 loss is cell autonomous, consistent with apparently normal expre

80 he mechanisms underlying these roles involve cell-autonomous control of signaling and gene expression

81 re was no effect of IL-1R2 deficiency on the cell-autonomous cytokine response to IL-1beta in the tes

82 This confers not only cell-autonomous cytoprotection but also paracrine establ

83 In this study, the classic non-cell-autonomous cytotoxicity of IFN was augmented by cel

84 Cell-autonomous cytotoxicity of type I interferon respon

85 lar concentration of DNMT3B are critical for cell-autonomous de novo DNA methylation in somatic cells

86 photoreceptors leads secondarily to the non-cell autonomous death of cone photoreceptors.

87 ic cascade in vitro and in vivo and causes a cell autonomous defect in invadopodial matrix degradatio

88 We report that CLYBL loss leads to a cell-autonomous defect in the mitochondrial B12 metaboli

89 that there are both cell autonomous and non-cell-autonomous defects in SMA motoneurons and astrocyte

90 ar process of autophagy, which is an ancient cell autonomous defense pathway that utilizes ER-derived

91 Thus, the cell autonomous defense system can mobilize and coalesce

92 Cell-autonomous defense mechanisms are potent strategies

93 innate branches of the immune system operate cell-autonomous defenses as key effector mechanisms that

94 Consistent with cell-autonomous degeneration, we demonstrate defects in

95 These results revealed that a non-cell-autonomous developmental input regulates intestinal

96 While cell-autonomous dynamics are well described, understandi

97 icroRNAs, but no intact EBV-DNA, linking non-cell-autonomous EBER1 presence with skin inflammation in

98 etween ATP/AMP efflux pathways and different cell-autonomous ectonucleotidases.

99 lar permeability in the tumors or a possible cell autonomous effect of DEP-1.

100 Adipocytes in culture showed a cell-autonomous effect in response to added TGF-beta1 or

101 pe of Ctnnb1(f/f);CtsKCre animals combines a cell-autonomous effect in the mature osteoclast with ind

102 rotection was due to a placental trophoblast cell-autonomous effect of autophagic activity, not to al

103 This reveals a cell-autonomous effect of Wnt/betacatenin signaling in c

104 beta receptor 2 (TgfbetaR2) mutation to show cell autonomous effects of TgfbetaR2 loss on ISC clonal

105 e that EMT contributes to metastasis via non-cell autonomous effects that activate the Hh pathway.

106 tion and to determine if they can induce non-cell-autonomous effects in neighboring neurons.

107 In a medium-transfer experiment in which the cell-autonomous effects of 5-aza was dissociated, CHOP a

108 ion present in Ts65Dn mice is in part due to cell-autonomous effects of trisomy on oligodendrocyte di

109 factors that are linked to the observed non-cell-autonomous effects on angiogenesis.

110 phagy in Ras(V12) clones also results in non-cell-autonomous effects with autophagy, cell proliferati

111 limited role for DNA damage as a mediator of cell-autonomous epigenetic dysfunction.

112 Additional Trp53 inactivation activates a cell-autonomous epithelial-to-mesenchymal transition pro

113 Our data suggest a non-cell-autonomous erythrocyte defect secondary to the sphi

114 s that until recently was mostly viewed as a cell-autonomous event.

115 ctivation of this pathway also reduced tumor cell-autonomous expression of target genes for the trans

116 ns of aging, selective vulnerability and non-cell-autonomous factors such as alpha-synuclein cell-to-

117 his analysis reveals that in the presence of cell-autonomous factors, networks can form a pattern wit

118 that PD pathology is governed by regional or cell-autonomous factors.

119 injury repair and skeletal regeneration in a cell autonomous fashion.

120 signaling promotes B lymphopoiesis in a non-cell-autonomous fashion in vitro, and depletion of the H

121 glia negatively influences neurons in a non-cell-autonomous fashion, and that in Mecp2-null mice, re

122 at knocking out D2Rs eliminates the ADP in a cell-autonomous fashion, confirming that this ADP depend

123 expanding HSC-derived hematopoiesis in a non-cell-autonomous fashion.

124 Our data describe a cell-autonomous feature of principal neurons, where tape

125 scence-associated stemness is an unexpected, cell-autonomous feature that exerts its detrimental, hig

126 We provide genetic evidence of a non-cell-autonomous feedback pathway regulating Fgf9, Fgf18

127 signaling while simultaneously inducing the cell-autonomous Fgf signaling inhibitor Dusp4 within the

128 These effects are shown to be primarily cell autonomous, from loss of alpha3(V) chains normally

129 (Rdh10 mutants) points to an important, non-cell-autonomous function for RA in the development of th

130 gions suggested that RA may have a separate, cell-autonomous function in brain endothelial cells to i

131 s of nod-1 sectors suggests that NOD plays a cell-autonomous function in the leaf.

132 human cancer, most knowledge focuses on its cell-autonomous functions in epithelial malignancies.

133 Here, we identify cooperative non-cell-autonomous functions of a single gene that together

134 ced cortical and trabecular bone, suggesting cell-autonomous functions of FGF signaling during postna

135 wild type for p53, allowing for the study of cell-autonomous functions.

136 This cell-autonomous genetic insult attenuated neuronal spiki

137 e of glycans biosynthesized by the canonical cell-autonomous glycosylation pathway, but subjected to

138 lycans by a process other than the canonical cell-autonomous glycosylation that occurs within the int

139 llel, studies of key factors responsible for cell autonomous growth in MYC amplified medulloblastoma

140 morigenicity by activating PKCiota-dependent cell autonomous Hedgehog (Hh) signaling.

141 set out to revisit the role of Hif-1alpha in cell-autonomous HSC functions.

142 onstrated that Hif-2alpha is dispensable for cell-autonomous HSC maintenance, both under steady-state

143 roenvironment, Hif-1alpha is dispensable for cell-autonomous HSC maintenance.

144 ata suggest an essential role for endogenous cell-autonomous human skeletal muscle oscillators in reg

145 , together with paradoxically robust, rapid, cell-autonomous IL-2 and IFNgamma production, equip live

146 erved signaling hub at the interface between cell-autonomous immunity and innate immune sensing pathw

147 Interferon exposure boosts cell-autonomous immunity for more efficient pathogen con

148 Constitutive cell-autonomous immunity in metazoans predates interfero

149 Cell-autonomous immunity is essential for host organisms

150 Cell-autonomous immunity relies on the ubiquitin coat su

151 tophagy are evolutionarily conserved arms of cell-autonomous immunity that restrict replication of in

152 pecific responses and their consequences for cell-autonomous immunity to a wide variety of microbial

153 l propagation by counteracting GBP-dependent cell-autonomous immunity.

154 vital dynamic and molecular perceptions into cell-autonomous immunity.

155 on is directed toward specific isotypes by a cell-autonomous imprinted state.

156 In conclusion, we found that the cell autonomous increase in Fgf23 secretion in Hyp osteo

157 nerate retinoic acid from retinol leading to cell-autonomous induction of the barrier-related ATP-bin

158 Cell-autonomous induction of type I interferon must be s

159 er cells through metabolic reprogramming and cell-autonomous inflammation.

160 ysis provides strong evidence supporting the cell-autonomous influence of mGluR5 signaling on the fun

161 sized the importance of gonadal hormones and cell-autonomous influences in mammals versus strictly ce

162 To examine the cell-autonomous influences of mGluR5 signaling in the mo

163 r was targeted, cells displayed elevated non-cell autonomous inhibition.

164 e-associated molecular patterns, can deliver cell-autonomous innate immune responses that may result

165 Here, we show that cell autonomous insulin signaling within the Drosophila

166 ple combinations, allowing us to measure non-cell autonomous interactions between cells with differin

167 AX2 1-LIKE3 (SMXL3), SMXL4, and SMXL5 act as cell-autonomous key regulators of phloem formation in Ar

168 ome and total proteome that is distinct from cell-autonomous KRAS(G12D) alone.

169 the number of regulated signaling nodes from cell-autonomous KRAS(G12D).

170 endent metabolite labeling, confirming tumor-cell-autonomous lactate uptake.

171 ing their synthetic lethal relationship at a cell autonomous level.

172 or embryonic cortical neurogenesis and novel cell-autonomous Lgl1 functions controlling RGP-mediated

173 In contrast, these cell-autonomous manipulations had no impact on inhibitor

174 euroblast are very precisely controlled in a cell autonomous manner, after quiescence extrinsic facto

175 of Nodal ligands Squint and Cyclops in a non-cell autonomous manner.

176 he adaptor molecule TRIF, and proceeded in a cell autonomous manner.

177 f-b acts in a cell autonomous as well as non-cell autonomous manner.

178 can directly tune neuronal excitability in a cell-autonomous manner by modulating IA.

179 n of adult neural stem/progenitor cells in a cell-autonomous manner in vitro and migration of their p

180 We show that NC Fn1 signals in an NC cell-autonomous manner through integrin alpha5beta1 expr

181 arly in disease but eventually acts in a non-cell-autonomous manner to promote disease progression.

182 gc1a(f/+)Alb-cre(+/0) mice of each sex, in a cell-autonomous manner, but was greater in livers from t

183 functions to regulate NSC proliferation in a cell-autonomous manner.

184 ugmented M2 polarization of macrophages in a cell-autonomous manner.

185 suggesting alphaBc might be acting in a non-cell-autonomous manner.

186 intake or are able to persist in vitro in a cell-autonomous manner.

187 s) control root system architecture in a non-cell-autonomous manner.

188 expression of synaptic vesicle proteins in a cell-autonomous manner.

189 fetal muscle progenitors via NOTCH in a non-cell-autonomous manner.

190 in-1 affects photoreceptor function in a non-cell-autonomous manner.

191 OMC expression via the JAK/STAT pathway in a cell-autonomous manner.

192 ot driven by miR-27 in effector T cells in a cell-autonomous manner.

193 s, indicating that neuroligins function in a cell-autonomous manner.

194 neration both in a cell-autonomous and a non-cell-autonomous manner.

195 Here we propose a cell-autonomous mechanism for adiposity as a result of p

196 dx-1 triggers proliferation largely by a non-cell-autonomous mechanism mediated by soluble factors.

197 These results define a non-cell-autonomous mechanism modulating Kras(G12D)-driven A

198 Molecular analysis reveals a non-cell-autonomous mechanism that causes widespread cell de

199 reduced PD-associated protein toxicity by a cell-autonomous mechanism that was time-dependent.

200 nflammation, thereby preventing HCC by a non-cell-autonomous mechanism.

201 ity and directional cell migration through a cell-autonomous mechanism.

202 endrocyte precursors suggested an underlying cell-autonomous mechanism.

203 In recent years, non-cell autonomous mechanisms of aggregate formation have c

204 This severe pathology occurred through cell autonomous mechanisms that triggered Purkinje cell

205 mmune response in postnatal NSCs through non-cell autonomous mechanisms.

206 cuit reorganization are determined by neuron-cell-autonomous mechanisms and by interactions among neu

207 on cardiomyopathy suggest that cardiomyocyte cell-autonomous mechanisms contribute to the compaction

208 nomous influences in mammals versus strictly cell-autonomous mechanisms in Drosophila melanogaster.

209 Moreover, post-transplantation non-cell-autonomous mechanisms restore the numbers of inters

210 ons in Ptpn11 induce a JMML-like MPN through cell-autonomous mechanisms that are dependent on Shp2 ca

211 hat besides the classic paracrine mechanism, cell-autonomous mechanisms that involve induction of ER

212 onomous cytotoxicity of IFN was augmented by cell-autonomous mechanisms that operated independently o

213 circuit stability is controlled both through cell-autonomous mechanisms that regulate some aspects of

214 the WNT pathway via non-cell-autonomous and cell-autonomous mechanisms to ensure the formation of an

215 is, through cell-autonomous and possibly non-cell-autonomous mechanisms, in a manner that was reverse

216 ective dysfunction of vulnerable neurons via cell-autonomous mechanisms.

217 Collectively, our findings highlight a cell-autonomous metabolic mechanism by which CR-CSCs exp

218 amino acid metabolism, but also affects non-cell-autonomous metabolic regulation by induced expressi

219 ction, and implicate a role for IL-34 in non-cell-autonomous, microglial-dependent neurodegeneration

220 Our results identify SPPL3 as a cell-autonomous molecular determinant of NK cell maturat

221 a heterogeneous network of neurons, in which cell-autonomous molecular feedback loops determine the p

222 Cell-autonomous molecular mechanisms that control the ba

223 ntermediates, and demonstrates the intrinsic cell-autonomous nature of these progenitors to different

224 cyte cocultures to investigate potential non-cell autonomous neuroprotective factors influencing Abet

225 retion in the HD brains, contributing to non-cell-autonomous neurotoxicity in HD.SIGNIFICANCE STATEME

226 cRs, we found that DcRs do not only act in a cell-autonomous or cis-regulatory manner, but also exert

227 This demonstrates a non-cell autonomous origin of this disease that is unexpecte

228 Some data implicate a cell-autonomous oscillation in gene expression, while ot

229 ially induce oscillations of auxin response: cell-autonomous oscillations, Turing-type patterning, an

230 Accumulation of non-cell autonomous Otx2 homeoprotein in postnatal mouse vis

231 fers neuroprotection through a potential non-cell-autonomous pathway that modulates mhtt aggregation

232 bolism, which is driven by oncogene-mediated cell-autonomous pathways, the unique physiology of the t

233 -ME2) disrupted both cell-autonomous and non-cell-autonomous pathways.

234 Additionally, cell-autonomous PDF signaling reversed the circadian beh

235 heterocellular process and that our existing cell-autonomous perspective underrepresents the extent o

236 In zebrafish, cell autonomous PKA inhibition also increased and sustai

237 in theta frequency bursts to understand how cell autonomous, postsynaptic activity leads to synapse

238 n Munc18-1 mutants and demonstrate that this cell-autonomous process does not appear to be a result o

239 erative diseases is hypothesized to be a non-cell-autonomous process that may be mediated by the prod

240 Non-cell autonomous processes involving astrocytes have been

241 blished literature has focused on neoplastic cell-autonomous processes for these adaptations.

242 nd lengthens lifespan has largely focused on cell-autonomous processes.

243 FGF19 triggers a previously unsuspected, non-cell-autonomous program to activate STAT3 signalling in

244 t mutant RAS has been shown to stimulate non-cell autonomous proliferation in malignancy and suggests

245 eIF2alpha phosphorylation regulates not only cell-autonomous proteostasis and amino acid metabolism,

246 These results demonstrate that a cell-autonomous, Rab32-dependent host defense pathway pl

247 at shock response is a universal homeostatic cell autonomous reaction of organisms to cope with adver

248 fer therapeutic cells that tightly integrate cell-autonomous recognition and user control.

249 Numerous studies have shown that non-cell-autonomous regulation of cancer cells is an importa

250 ular development via non-cell-autonomous and cell-autonomous regulation of endothelial WNT signaling.

251 resent evidence that the Arp2/3 complex is a cell-autonomous regulator of neuronal migration.

252 n of a Cre-expression construct identified a cell-autonomous requirement for paxillin in migrating ne

253 The CNS myelination defect results from a cell-autonomous requirement for THAP1 in the OL lineage

254 Our studies reveal a novel, cell-autonomous requirement of CBL and CBL-B in epitheli

255 CreERT2, to demonstrate a mammary epithelial cell-autonomous requirement of CBL and CBL-B in the main

256 autonomous roles in cell flattening from non-cell-autonomous requirements for MTs in regulating proli

257 Activation by IFN-gamma induced a cell-autonomous response in hLECs via autophagy and NO p

258 dings identify stress-mediated ER-phagy as a cell-autonomous response mobilized by STING-dependent se

259 gnals controlling deployment of constitutive cell-autonomous responses during infection have remained

260 The results also suggest a non-cell autonomous role for BDNF in the DRN in mediating an

261 toxic to motor neurons (MNs) and play a non-cell autonomous role in disease pathogenesis.

262 In this study, we identify an unexpected non-cell autonomous role of epidermal polarity proteins, mol

263 These data demonstrate the cell autonomous role of the glycolytic pathway in outer

264 These findings reveal a key cell-autonomous role for BSCL2 in controlling BAT mass/a

265 These findings demonstrate a direct and cell-autonomous role for E2F activators in human cancer.

266 developing mesothelium reveals a mesothelial cell-autonomous role for Ezh2 in repression of the smoot

267 se findings are the first demonstration of a cell-autonomous role for hepcidin in iron homeostasis.

268 esults in the same deficiencies, revealing a cell-autonomous role for SPPL3 in these processes.

269 and live imaging, we show that KIF20B has a cell-autonomous role in cytokinesis.

270 Hoxa5 does not play a cell-autonomous role in lung epithelium, consistent with

271 Thus, ANG plays a non-cell-autonomous role in regulation of hematopoiesis by s

272 iated knockdown, we showed that Fmr1 plays a cell-autonomous role in the phagocytosis of bacteria.

273 Here we report a cell-autonomous role of MyD88 in the regulation of myobl

274 To study the cell-autonomous role of p53 in thymic epithelium functio

275 neuronal dysfunction, our findings reveal a cell-autonomous role of pejvakin in maintaining stereoci

276 e we conducted mosaic analysis to reveal the cell-autonomous role of the metabotropic glutamate recep

277 a reveal a previously unappreciated critical cell-autonomous role of TNF on monocytes for their survi

278 Astrocytes perform critical non-cell autonomous roles following CNS injury that involve

279 We uncoupled cell-autonomous roles in cell flattening from non-cell-a

280 Bone marrow chimera experiments revealed a T cell-autonomous selective disadvantage of CD6(-/-) T cel

281 ation, they gradually returned to a precise, cell-autonomous set point during periods of active wake,

282 underlie this model, but the contribution of cell-autonomous signaling components is largely unknown.

283 In this study, we describe a cell-autonomous signaling mechanism explaining how tenas

284 ing evidence suggests Notch also directs non-cell-autonomous signalling in adult tissues.

285 versity of homotypic BcR contacts leading to cell-autonomous signalling reconciles the existence of a

286 o distant tissues, where they may act as non-cell-autonomous signals.

287 tive transgenes, and discover conditions for cell-autonomous silencing in animals with tissue-specifi

288 rictly in the same cell or also mediates non-cell-autonomous Smo inhibition, we generated genetically

289 med cell death (PCD) is usually considered a cell-autonomous suicide program, synonymous with apoptos

290 impair the synthesis of Ecdysone and produce cell-autonomous survival defects, but the mechanisms by

291 of magnesium ions, [Mg(2+)]i, which act as a cell-autonomous timekeeping component to determine key c

292 Circadian clocks are cell-autonomous timing mechanisms that organize cell fun

293 a stage preceding aggregation, detecting non-cell-autonomous toxicity and evaluating how some of the

294 in physiology, metabolism, and behavior via cell-autonomous transcriptional feedback loops.

295 SCN timekeeping is sustained by a cell-autonomous transcriptional-translational feedback l

296 lates E/I synapse density predominantly as a cell-autonomous, transcriptional repressor.

297 l death, but rather of upregulation of tumor-cell-autonomous type I interferon (IFN) signaling and a

298 cial for axonal pruning and contributes in a cell autonomous way.

299 nd functions in both cell-autonomous and non-cell-autonomous ways to promote tissue adaptation to inj

300 XCI is thought to be cell autonomous, with all factors required being produce