ライフサイエンスコーパス: cell-cycle regulatory protein

1 ments that contribute to inactivation of the cell cycle regulatory protein.

2 promoting ubiquitination and degradation of cell cycle regulatory proteins.

3 cations of detecting alterations in critical cell cycle regulatory proteins.

4 probably results from altered degradation of cell cycle regulatory proteins.

5 em for the identification and examination of cell cycle regulatory proteins.

6 controlled at the level of the cell cycle by cell cycle regulatory proteins.

7 d proteolysis controls the abundance of many cell cycle regulatory proteins.

8 lexes containing DNA replication, repair and cell cycle regulatory proteins.

9 lation of proteasome-mediated degradation of cell cycle regulatory proteins.

10 eration was mediated, in part, by effects on cell cycle regulatory proteins.

11 e complexes modulate the accumulation of key cell cycle regulatory proteins.

12 cogene, Tre2, as well as mammalian and yeast cell cycle regulatory proteins.

13 riptional activation by Tax is influenced by cell cycle regulatory proteins.

14 45 induced G2/M arrest and downregulation of cell cycle regulatory proteins.

15 kinase pathway and subsequent expression of cell cycle regulatory proteins.

16 mitosis by catalyzing ubiquitination of key cell cycle regulatory proteins.

17 n in UV-mediated increases in these critical cell cycle regulatory proteins.

18 proteins including RNA binding proteins and cell cycle regulatory proteins.

19 ivation and phosphorylation of apoptotic and cell cycle regulatory proteins.

20 sis and can phosphorylate many apoptotic and cell cycle regulatory proteins.

21 itously expressed transcription factors, and cell cycle regulatory proteins.

22 to altered proteasomal degradation of these cell cycle regulatory proteins.

23 ent junctures by the targeted destruction of cell cycle regulatory proteins.

24 ated, at least in part, by downregulation of cell cycle regulatory proteins.

25 These results suggest that Wolbachia target cell cycle regulatory proteins.

26 y regulating the activities of these crucial cell cycle-regulatory proteins.

27 infection leads to dysregulation of multiple cell cycle-regulatory proteins.

28 and subcellular compartmentalization of key cell-cycle regulatory proteins.

29 ed NF-kappaB activation and up-regulation of cell-cycle regulatory proteins.

30 NA transcripts, including those encoding key cell-cycle regulatory proteins.

31 modulating the expression of aforementioned cell-cycle regulatory proteins.

32 ine AN3CA, MIS affects the expression of key cell-cycle regulatory proteins.

33 thase and ubiquitin-dependent proteolysis of cell-cycle regulatory proteins.

34 D 98059 mimicked the effects of CWF on these cell-cycle-regulatory proteins.

35 In addition to regulating the expression of cell cycle-regulatory proteins, 7,3',4'-THIF bound to CD

36 th arrest and DNA damage 45 (GADD45alpha), a cell cycle regulatory protein activated by genotoxic str

37 on studies have shown that overexpression of cell cycle regulatory proteins affects the transcription

38 Of particular interest, transcripts encoding cell cycle-regulatory proteins, alpha- and beta-tubulins

39 inoblastoma family member RB2/p130 encodes a cell cycle regulatory protein and has been found mutated

40 al EBV latent antigen's directly targeting a cell cycle regulatory protein and suggests a novel mecha

41 is thought to control mitosis by binding to cell cycle regulatory proteins and altering their activi

42 To determine the possible association of cell cycle regulatory proteins and apoptotic cell death

43 s transient alterations in the expression of cell cycle regulatory proteins and by decreased telomera

44 Expression of critical cell cycle regulatory proteins and cell division require

45 d associated downstream events and modulates cell cycle regulatory proteins and progression, leading

46 rresponding changes in the expression of key cell cycle regulatory proteins and prolonged activation

47 nvolves a genetic interaction between BMP10, cell cycle regulatory proteins and several major cardiac

48 r protein required for the ubiquitination of cell cycle regulatory proteins and transcriptional facto

49 effect blocks the transcription of important cell-cycle regulatory proteins and results in cell-cycle

50 toma (Rb) phosphorylation, the expression of cell cycle regulatory proteins, and CDK activity.

51 l in quiescence, governing the expression of cell cycle regulatory proteins, and completing of absorp

52 igation blocked IL-2 activation of genes and cell cycle regulatory proteins, and suppressed cell prol

53 was no effect on MyoD-induced activation of cell cycle regulatory proteins, and thus, cells arrested

54 ted DNA damage, up-regulated c-Myc and other cell-cycle regulatory proteins, and induced proliferatio

55 A number of cell cycle regulatory proteins are known to be degraded

56 biquitination and proteasomal degradation of cell cycle regulatory proteins are known to play a pivot

57 the effects of N1,N11-diethylnorspermine on cell cycle regulatory proteins associated with G1 arrest

58 ds to diverse perturbations in signaling and cell cycle-regulatory proteins, associated with a marked

59 been found to functionally interact with the cell cycle regulatory proteins ATM and BRCA1; however, t

60 BTAs differentially express cell cycle-regulatory proteins based on tumor location a

61 ned telomeres, increased G2/M phase, altered cell-cycle regulatory proteins but nontumorigenic.

62 pha is known to downregulate cyclin A, a key cell cycle regulatory protein, but little else is known

63 The ubiquitination of cell cycle regulatory proteins by the anaphase-promoting

64 The ubiquitylation of cell-cycle regulatory proteins by the large multimeric a

65 d factor TAF(II)250, first identified as the cell cycle regulatory protein CCG1.

66 Besides ORC, MCM proteins, cell-cycle regulatory proteins, checkpoint proteins, 60S

67 These results support the notion that cell cycle regulatory proteins congress and interact in

68 pression and cytoplasmic localization of key cell cycle regulatory proteins control germline cyst pro

69 ted, at least in part, by an increase in the cell cycle regulatory protein cyclin A.

70 rbs cellular proliferation by regulating the cell cycle regulatory protein cyclin D1 and the ROS scav

71 e induction also leads to degradation of the cell cycle regulatory protein cyclin D1.

72 eported that human SAMHD1 interacts with the cell cycle regulatory proteins cyclin A, CDK1, and CDK2,

73 lot analyses revealed that the levels of the cell cycle regulatory proteins cyclin B1 and the cyclin-

74 modulation in the expression and function of cell cycle regulatory proteins cyclin-D1 and -D2, cdk-2,

75 mechanism governing Mphi proliferation, the cell cycle regulatory protein, cyclin E, was rapidly upr

76 NF-kappaB transactivates the cell-cycle regulatory protein, cyclin D1, which causes i

77 or induction of anti-apoptotic proteins plus cell cycle regulatory proteins during antigen receptor m

78 may be regulated by its interaction with the cell cycle regulatory protein, E2F-1.

79 known factors were identified, including the cell cycle regulatory proteins E2F1 and Rb.

80 ion, resulting in the down-regulation of the cell-cycle regulatory protein E2F3.

81 rmissive cells by altering expression of key cell cycle regulatory proteins either directly or indire

82 3, suggesting that mechanisms that alter the cell cycle regulatory proteins, either by interaction wi

83 Certain cell cycle regulatory protein expression and activities

84 t alter the AGN193198-dependent reduction in cell cycle regulatory protein expression and activity, s

85 athologic study characterizes differences in cell cycle-regulatory protein expression across the spec

86 50 was correlated with different profiles of cell cycle-regulatory protein expression.

87 subunit E3 ubiquitin ligase that targets key cell cycle regulatory proteins for degradation.

88 it E3 ubiquitin ligase that targets specific cell cycle regulatory proteins for ubiquitin-dependent d

89 estrates cell-cycle progression by targeting cell-cycle regulatory proteins for destruction via the u

90 nical mechanism termed multiple fission, the cell cycle regulatory proteins from Chlamydomonas are re

91 nscriptional regulators, signaling proteins, cell cycle regulatory proteins, growth factors, and cyto

92 Speedy (Spy1), a novel cell cycle regulatory protein, has been found to prematu

93 T-cell leukemia virus type 1 (HTLV-1) and a cell cycle regulatory protein have been examined.

94 (HCMV) immediate-early (IE) proteins and key cell cycle regulatory proteins have been suggested as a

95 esis of viral-induced tumors and the role of cell cycle regulatory proteins in brain tumor formation

96 engagement on the expression and activity of cell cycle regulatory proteins in CD34(+) cells under co

97 xpression/activity of multiple signaling and cell cycle regulatory proteins in PMA-treated leukemia c

98 governed by the concerted action of numerous cell cycle regulatory proteins in response to signals bo

99 MC with conditional inactivation of negative cell cycle regulatory proteins in the context of smooth

100 We also observed a decrease in all cell cycle regulatory proteins in the innermost spheroid

101 N2A locus on chromosome 9p21 and function as cell cycle regulatory proteins in the p53 and RB pathway

102 KCdeltaEC) to determine the role of specific cell cycle regulatory proteins in the PKCdelta-induced c

103 We have analysed several cell cycle regulatory proteins in these G1 arrested cell

104 DNA, DNA-PK will phosphorylate p53 and other cell cycle regulatory proteins in vitro, and DNA-PKcs sh

105 expression of surface activation markers and cell cycle-regulatory proteins in MV-infected human T ly

106 e, involves the activation of DNA repair and cell cycle regulatory proteins including the MRN (Mre11,

107 is and growth by physically interacting with cell cycle regulatory proteins including the retinoblast

108 In contrast, expression of G1 cell cycle regulatory proteins, including p27KIP1, cycli

109 ed in ubiquitin-dependent proteolysis of key cell cycle regulatory proteins, including the destructio

110 We have assessed the status of endogenous G1 cell cycle regulatory proteins, including the tumor supp

111 d in multiple perturbations in signaling and cell cycle-regulatory proteins, including down-regulatio

112 tors in kinases and phosphatases) in several cell cycle regulatory proteins indicate periodic oscilla

113 Analysis of cell cycle profile and cell cycle regulatory proteins indicated that arsenite a

114 Examination of cell cycle regulatory proteins indicated that p53 does n

115 Spy1 therefore represents a novel cell cycle regulatory protein, inducing maturation throu

116 rapeutic targets including cyclin D1 and the cell cycle regulatory proteins, inhibitors of mammalian

117 The gene encoding CtrA, a key cell cycle regulatory protein, is transcribed from two p

118 products interact with the Aspergillus NIMA cell cycle regulatory protein kinase, reveals that it en

119 Prohibitin (PHB) is a cell cycle regulatory protein, known to repress E2F1-med

120 Conversely, alterations in cell cycle regulatory proteins, leading to the loss of n

121 g that caspase activation and suppression of cell cycle regulatory protein levels are independent pro

122 cell cycle arrest and decrease expression of cell cycle regulatory proteins like cyclin E, cyclin D1

123 Mutations in cell cycle regulatory proteins occur frequently in tumor

124 A different pattern of changes in cell cycle regulatory proteins occurred, however, after

125 er, have revealed that Id binds to important cell cycle regulatory proteins other than bHLH proteins.

126 The INK4a/ARF locus encodes two cell cycle-regulatory proteins, p16INK4a andp14ARF, whic

127 with enhanced ATRA-mediated up-regulation of cell cycle regulatory proteins p21waf1 and p27kip1, reti

128 The kinase inhibitory domain of the cell cycle regulatory protein p27(Kip1) (p27) was nuclea

129 Here we describe the oxidation of a cell-cycle regulatory protein, p53, from a distance thro

130 Because of the importance that the cell cycle regulatory proteins play in tumorigenesis, cu

131 The key cell cycle regulatory protein, pRb, can be harnessed to

132 ic targets, including the cell signaling and cell cycle regulatory proteins, pro-apoptotic family mem

133 recently, proteasome-mediated degradation of cell cycle regulatory proteins, production and loading o

134 yme was developed that targets the mRNA of a cell cycle regulatory protein, proliferating cell nuclea

135 ypothesize that interactions between LRP and cell cycle regulatory proteins promote survival of postm

136 e proteins were categorized as proliferation/cell cycle regulatory proteins, proteins involved in spl

137 ntly affect Taxol-induced alterations in the cell cycle regulatory proteins Rb, p53, p21/Waf1 and Cdk

138 n SWI-SNF complex and cyclin E, an essential cell cycle regulatory protein required for G1/S transiti

139 oma PC12 cell-cycle arrest via regulation of cell-cycle regulatory proteins, resulting in differentia

140 are known to target and inactivate two main cell cycle regulatory proteins, retinoblastoma protein (

141 Analysis of CRC cell cycle regulatory proteins showed that reducing Id2

142 environment are probably known, as are most cell cycle regulatory proteins, signaling molecules and

143 h CksHs1, a human homolog of essential yeast cell cycle-regulatory proteins suc1 and Cks1, reveals th

144 lyzes the ubiquitin-dependent proteolysis of cell cycle regulatory proteins such as anaphase inhibito

145 ses (HPVs) binds to and alters the action of cell cycle regulatory proteins such as members of the re

146 ion signal and is highly homologous to other cell cycle regulatory proteins such as mitosin and centr

147 se processivity factor, PCNA, interacts with cell cycle regulatory proteins such as p21(WAF1/Cip1) an

148 Little is known about alterations in cell cycle regulatory proteins such as p53 and WAF1 in d

149 53 function and consequent reductions in the cell-cycle regulatory proteins such as p21.

150 ression and exit by enhancing degradation of cell cycle regulatory proteins, such as CYCB1;1, whose t

151 ut are unable to appropriately down-regulate cell cycle regulatory proteins, such as cyclin and cdc2

152 region and cell type-specific expression of cell cycle regulatory proteins, such as demonstrated for

153 Expression of cell cycle-regulatory proteins, such as cyclin-D1, cycli

154 involved in regulating the stability of key cell-cycle regulatory proteins, such as the cyclin-depen

155 CDK2 is a key cell cycle regulatory protein that controls the transiti

156 Mammalian Mip/LIN-9 is a cell cycle regulatory protein that is negatively regulat

157 Expression of a triad of cell cycle regulatory proteins that includes p73, p15, a

158 e subunit) proteins are essential eukaryotic cell cycle regulatory proteins that physically associate

159 Cyclin D1 (CCND1) is a key cell cycle regulatory protein, the overexpression of whi

160 ts cell growth by altering the expression of cell cycle regulatory proteins, thus causing a cell cycl

161 ffected the levels and activities of various cell cycle-regulatory proteins to induce normally quiesc

162 ion is associated with altered expression of cell cycle regulatory proteins, treatment results in ret

163 tionally for normal accumulation of the core cell cycle regulatory proteins Twine and CycB in mature

164 In previous studies we identified CDC37, a cell cycle regulatory protein, using a monoclonal antibo

165 Expression of cell cycle regulatory proteins was determined to evaluat

166 ion of IL-2, IL-2R-alpha, and the major G(1) cell cycle regulatory proteins was not altered in p18-nu

167 Subcellular localization of cell cycle-regulatory proteins was determined by immunof

168 ), known to modulate the expression of these cell-cycle-regulatory proteins, was examined.

169 the relationship between cyclin D1 and other cell cycle regulatory proteins, we established human gli

170 , F-boxes have been found within a number of cell cycle regulatory proteins, where they mediate ubiqu

171 on and hypertrophy are regulated by specific cell-cycle regulatory proteins, where the cyclin-depende

172 The identity of DNA replication proteins and cell cycle regulatory proteins which can be found in com

173 The cell cycle regulatory proteins, which include the cyclin