ライフサイエンスコーパス: cell-mediated

1 This suggests that UAG is subject to target cell-mediated activation - a novel mechanism for manipul

2 , intranodal T cell migration, and dendritic cell-mediated activation of antiviral CD8+ T cells.

3 apoptosis was initiated by multiple myeloma cell-mediated activation of Notch signaling and was furt

4 enteric lymph nodes [mLNs] causing reduced T cell-mediated adaptive immune responses (in particular T

5 nfected cells, peak ADCC antibody titres, NK cell-mediated ADCC and antibody-mediated activation of M

6 l neovascularization increases the risk of T cell-mediated allograft rejection.

7 ed adhesion may provide a new insight into T cell-mediated alloresponses and may pave the way to the

8 ial of transplantation is often reduced by T cell-mediated alloresponses that cause graft rejection o

9 d HSV-2 virions to mucosal APCs, enhancing T cell-mediated and Ab-mediated responses to the infection

10 ticle, although wild-type C57BL/6 mice mount cell-mediated and humoral adaptive immune responses to Z

11 ed in dark nights, then tested as adults for cell-mediated and humoral immunity.

12 ll function and thereby stimulate adaptive T cell-mediated anti-cancer immunity.

13 However, its role in NK cell-mediated anti-microbial signaling remains unclear.

14 dence that HSP90 inhibition can potentiate T-cell-mediated anti-tumor immune responses, and rationale

15 MDSCs promote tumor growth by blocking T-cell-mediated anti-tumoral immune response through deple

16 ecific CD4(+) T-cell responses, as well as B-cell-mediated antibody production.

17 ction mice were found to have defective B1 B-cell-mediated antibody responses against the T-cell-inde

18 ular regulatory T cells, and inhibit the TFH cell-mediated antibody secretion.

19 CMV-T cell activity, anti-CMV IgG, and NK cell-mediated antibody-dependent cell cytotoxicity were

20 atural killer (NK)-cell degranulation and NK-cell-mediated antibody-dependent cellular cytotoxicity (

21 l antibody (mAb) directs natural killer (NK) cell-mediated antibody-dependent cellular cytotoxicity (

22 T regulatory cells (huTreg) suppress CD4+ T cell-mediated antipig xenogeneic responses in vitro and

23 enhancement of Th1-mediated and cytotoxic T-cell-mediated antitumor immunity.

24 ighten therapeutic benefits by augmenting NK cell-mediated antitumor immunity.Significance: Ablating

25 on of pancreatic tumors in mice activates NK cell-mediated antitumor responses and inhibits local rec

26 f GIT microbial dysbiosis on infant CD8(+) T cell-mediated antiviral immunity.

27 a directly interacting host protein as a new cell-mediated antiviral mechanism.

28 napse and potently induce antibody-dependent cell-mediated antiviral responses: (i) the interaction b

29 d cells for the development of TH2- and TH17-cell mediated asthma.

30 Myasthenia gravis (MG) is a prototypical B cell-mediated autoimmune disease affecting 20-50 people

31 Type 1 diabetes is a T cell-mediated autoimmune disease that is characterized b

32 een shown to contribute to the etiology of T-cell-mediated autoimmune diseases through the upregulati

33 ing to non-lymphoid organs, causing CD8(+) T-cell-mediated autoimmune diseases.

34 ctive against multiple sclerosis and other T-cell-mediated autoimmune diseases.

35 be exploited as a therapeutic approach to T cell-mediated autoimmune diseases.

36 apeutic approaches for the treatment of TH17-cell-mediated autoimmune diseases.

37 ndings highlight how HuR contributes to Th17 cell-mediated autoimmune neuroinflammation and support t

38 Celiac disease is a human T cell-mediated autoimmune-like disorder caused by exposur

39 l immune responses, and are protected from T cell-mediated autoimmunity and alloimmunity in models of

40 methylation in immune responses, including T cell-mediated autoimmunity and EAE.

41 t of treatments that selectively target TH17 cell-mediated autoimmunity but do not affect thymocyte d

42 ate immunity influences the development of T cell-mediated autoimmunity in multiple sclerosis and its

43 tors as potential targets for therapies of T cell-mediated autoimmunity.

44 ne protein UIS3 to avoid elimination by host-cell-mediated autophagy.

45 ) subset that suppresses follicular helper T cell-mediated B cell responses in the germinal center re

46 target biofilm specific components for host-cell mediated bacterial clearance.

47 transplanted osteogenic cells for effective cell-mediated bone repair.

48 he first report of Cam uptake into bacterial cells mediated by a specific transporter protein.

49 mechanism of regulated viral entry in animal cells mediated by host factor villin.

50 indicating intriguing turning behavior of T cells mediated by lamellipodia formation and MLCK activi

51 s revealed how interactions between adjacent cells mediated by Notch regulate development and physiol

52 a higher number and magnitude of NG2+ mural-cell mediated capillary constrictions in the hippocampus

53 Moreover, dendritic cell-mediated capture of particulate antigen in this for

54 RESULT: CD4 T cell-mediated cardiac graft rejection is inhibited using

55 Ultimately, these events promote cytotoxic T-cell-mediated clearance of tumour cells, which is furthe

56 m lethal WNV infection by promoting CD8(+) T cell-mediated clearance of WNV.

57 key regulator in driving autoimmune CD4(+) T cell-mediated CNS damage.

58 y found in the mesenteric lymph node after T cell-mediated colitis induction, and their appearance pr

59 stemic infection with Candida albicans and T cell-mediated colitis.

60 iew leading HIV cure strategies that harness cell-mediated control against HIV in stably suppressed a

61 s whereby HIV infection impedes successful T cell-mediated control of M. tuberculosis have not been w

62 PD-1, Lag-3, and TIGIT, thereby limiting NK cell-mediated control of pulmonary metastases.

63 mphocyte attraction, together with dendritic cell-mediated cross-priming, are the key elements.

64 e numbers in the CNS and attenuated Th1/Th17 cell-mediated cytokine production.

65 transfer experiments and antibody-dependent cell-mediated cytotoxicity (ADCC) assays indicate that t

66 Moreover, antibody-dependent cell-mediated cytotoxicity (ADCC) assays revealed that t

67 Antibody-dependent cell-mediated cytotoxicity (ADCC) by non-neutralizing an

68 or cell susceptibility to antibody-dependent cell-mediated cytotoxicity (ADCC) by selective desialyla

69 for cancer treatment via antibody-dependent cell-mediated cytotoxicity (ADCC) has been little studie

70 ication and resistance to antibody-dependent cell-mediated cytotoxicity (ADCC).

71 therapeutic antibodies, complement-dependent cell-mediated cytotoxicity (CDCC) and complement-depende

72 not males were correlated with Ab-dependent cell-mediated cytotoxicity activity against gp120 target

73 cell assay, and moderate antibody-dependent, cell-mediated cytotoxicity activity was demonstrated.

74 Cell-mediated cytotoxicity against chondrocytes was eval

75 n-like transcript 1 (LLT1) interaction in NK cell-mediated cytotoxicity against normal human articula

76 antibodies weakly induced antibody-dependent cell-mediated cytotoxicity and enhanced induction in the

77 G2D receptors, and decreases NKG2D-dependent cell-mediated cytotoxicity and IFN-gamma production.

78 dase inhibition, in vitro antibody-dependent cell-mediated cytotoxicity and in vivo protection agains

79 ion, resulting in greater antibody-dependent cell-mediated cytotoxicity compared with IL-21 and/or an

80 Although CD4 T cell-mediated cytotoxicity has been reported in multiple

81 me B (GzmB) is a serine protease involved in cell-mediated cytotoxicity in conjunction with the pore-

82 variants demonstrated no antibody-dependent cell-mediated cytotoxicity in vitro against Daudi cells

83 lular phagocytosis and/or antibody-dependent cell-mediated cytotoxicity in vitro Our antibodies, spec

84 regulate the magnitude of antibody-dependent cell-mediated cytotoxicity induction.

85 Cell-mediated cytotoxicity might be key to controlling i

86 mplement-dependent cytolysis or Ab-dependent cell-mediated cytotoxicity of immortalized human hepatoc

87 t-dependent cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and antibody-dependent cellu

88 t depletes eosinophils by antibody-dependent cell-mediated cytotoxicity, for patients with severe, un

89 yeloid effector cells for antibody-dependent cell-mediated cytotoxicity, were similar between wild-ty

90 on of IgG via CD16a and execute Ab-dependent cell-mediated cytotoxicity, which is critical for the ef

91 chanisms likely involving antibody-dependent cell-mediated cytotoxicity.

92 ell activation, proliferation, and bystander cell-mediated cytotoxicity.

93 S response also directly suppressed CD8(+) T-cell-mediated cytotoxicity.

94 ucers and did not inhibit antibody-dependent cell-mediated cytotoxicity.

95 BB signaling can increase antibody-dependent cell-mediated cytotoxicity.

96 l as Fc-gamma-dependent, antibody-dependent, cell-mediated cytotoxity in both murine IgG2a and human

97 ell functions is necessary to prevent immune cell-mediated damage to healthy tissues.

98 e and complimentary mechanisms in the immune cell-mediated death of cancer cells.

99 Armored CAR T cells mediated depletion of tumor associated macrophages

100 Type 1 diabetes (T1D) results from T cell-mediated destruction of insulin-producing beta-cell

101 Type 1 diabetes (T1D) results from a T cell-mediated destruction of pancreatic beta-cells follo

102 This could be linked to mast cell-mediated digestive inflammation among patients with

103 ll depleted mice, suggesting IFN-gamma and T cell mediated disease mechanisms.

104 hown that psoriasis represents a bona fide T cell-mediated disease primarily driven by pathogenic T c

105 mas has made CD22 a therapeutic target for B cell-mediated diseases.

106 ceutical drug development for treatment of T-cell-mediated disorders.

107 is important in the immunopathogenesis of T-cell mediated drug hypersensitivity syndromes.

108 ft-versus-leukemia (GVL) benefit through a T-cell-mediated effect, most likely due to ITK inhibition.

109 zed mouse model to evaluate in vivo human NK cell-mediated elimination of HIV-1-infected cells by ADC

110 Although anti-IL-13 reduced nTreg cell-mediated enhancement, it was ineffective in iTreg c

111 ted enhancement, it was ineffective in iTreg cell-mediated enhancement; conversely, anti-IL-17, but n

112 se findings support the importance of immune cell-mediated esophageal injury in esophagitis and confi

113 Here, we studied whether T cell-mediated ET-1 production system exists and operates

114 hough elimination of RORgammat prevents TH17 cell-mediated experimental autoimmune encephalomyelitis

115 as a common signaling node to transmit tumor cell-mediated extrinsic or intrinsic signals, respective

116 n-induced enterocolitis (FPIES) is a non-IgE cell- mediated food allergy that can be severe and lead

117 ng viral infection and are susceptible to NK cell-mediated fratricide in a perforin- and NKG2D-depend

118 431-439-specific CD8(+) cells without CD4(+) cells mediated glomerular injury when MPO was planted in

119 Treg cells efficiently suppressed effector T cell-mediated graft-versus-host disease after allogeneic

120 on target cells is crucial for promoting NK cell-mediated graft-versus-leukemia effects.

121 Prior work has shown that CD4+ T cell-mediated GVL against CP-CML and BC-CML required int

122 ssociated with susceptibility to severe iNKT cell-mediated hepatitis, thus demonstrating the importan

123 -based strategies will be a superior path to cell-mediated HIV control and eradication.

124 ese antibodies may provide the basis for a B cell-mediated HIV-1 vaccine.

125 g in embryonic development but also for stem cell-mediated homeostasis and cancer.

126 tor (ICOS)-ICOS ligand cell contact for Treg cell-mediated ILC2 suppression alongside the suppressive

127 IL-10 acts to inhibit potentially protective cell mediated immune responses against B. pseudomallei,

128 rated that white dLAN compromises innate and cell mediated immune responses in adult Siberian hamster

129 inst Ct should elicit protective humoral and cell-mediated immune (CMI) responses in the genital trac

130 cell recognition but allows for improved NK cell-mediated immune control of a human gamma-herpesviru

131 d human donor-reconstituted mice improved NK cell-mediated immune control of EBV infection, indicatin

132 Although a general reduction in cell-mediated immune cytokine and chemokine (gamma inter

133 Thus, brain ischemia compromises NK cell-mediated immune defenses through mechanisms that di

134 ptor 1 (PD-1)/PD-L1 interaction to enhance T cell-mediated immune function, yet the effectiveness of

135 ocation of escape mutations in response to T-cell-mediated immune pressure in a cohort of 17 persons

136 ated protein 4 (CTLA4), down-regulates the T-cell-mediated immune response (called immune checkpoints

137 djuvanted formulations at eliciting a robust cell-mediated immune response and blocking the establish

138 linical disease and induced cross-protective cell-mediated immune response in a pig model.

139 patients during the acute phase of IM and a cell-mediated immune response that is qualitatively simi

140 her iNKT cells can participate in the innate cell-mediated immune response to HIV-1.

141 l (>32 times of IgG1 levels vs alum) and the cell-mediated immune responses against the encapsulated

142 ssible source of immune cells to investigate cell-mediated immune responses against tularemia, whose

143 hibit T cell activation and, thus, control T cell-mediated immune responses in numerous inflammatory

144 receptors (TLRs) play an important role in B cell-mediated immune responses in periodontal disease.

145 we determined serum levels of cytokines and cell-mediated immune responses in pigs.

146 Type-2-cell-mediated immune responses play a critical role in m

147 ncy virus (HIV) infection, naturally induced cell-mediated immune responses rarely eradicate infectio

148 vide a basis for detailed investigation of T cell-mediated immune responses to PVM in a variety of ge

149 T cell-mediated immune responses to the grafted tissues ar

150 Thus, active suppression of cell-mediated immune responses under immunocompromised c

151 uences is necessary for developing effective cell-mediated immune responses using L. monocytogenes-ba

152 emonstrate that PD-L1 selectively enhances T cell-mediated immune responses, suggesting a context-dep

153 To reactivate latent virus and boost cell-mediated immune responses, we performed in vivo Tre

154 ccine induced virus-specific CD4 + and CD8 + cell-mediated immune responses.

155 t adjuvants, particularly adjuvants inducing cell-mediated immune responses.

156 yA infection elicited protective humoral and cell-mediated immune responses.

157 ection influences the generation of CD8(+) T-cell-mediated immune responses.

158 function, although the mechanism of myeloid cell-mediated immune surveillance remains unclear.

159 both neutralizing antibodies and protective cell mediated immunity.

160 d to provide convincing evidence of improved cell mediated immunity.

161 (MeV) neutralizing antibody concentrations, cell-mediated immunity (CMI), and immunoglobulin G (IgG)

162 Exposed birds had significantly lower cell-mediated immunity (measured using phytohaemagglutin

163 U treatment in optimally activating a CD4+ T cell-mediated immunity against actinic keratoses and, po

164 these have the purpose to promote adaptive T cell-mediated immunity against cancer.

165 ittle is known about the cross-reactivity of cell-mediated immunity against drifted strains in childr

166 ex (MHC) class I proteins initiates CD8(+) T cell-mediated immunity against pathogens and cancers.

167 nimals with paucibacillary disease have high cell-mediated immunity and variable levels of antibody.

168 This finding points to cell-mediated immunity as a relevant pathogenetic mechan

169 not associated with alterations in CD4(+) T cell-mediated immunity but was preceded by enhanced neut

170 It is possible that diminished cell-mediated immunity during pregnancy could increase v

171 Consequently, the protective role of cell-mediated immunity in the control of dengue infectio

172 ay a major role in the improvement, and that cell-mediated immunity is the key to understanding E. co

173 Central to CD8(+) T cell-mediated immunity is the recognition of peptide-maj

174 e response and no effect on other markers of cell-mediated immunity or systemic and gut inflammation.

175 virus (HCV) infection decreases humoral and cell-mediated immunity responses to hepatitis B vaccinat

176 s is an emerging approach to elicit CD8(+) T cell-mediated immunity targeting pathogens and tumor Ags

177 ytotoxic T cells and natural killer cells of cell-mediated immunity to provide tumor (B16-ova-Melanom

178 llular and molecular understanding of type-2-cell-mediated immunity, as well as new areas such as the

179 candidate adjuvant capable of driving potent cell-mediated immunity, but the mechanism by which it ac

180 herefore play a nonredundant role in T and B cell-mediated immunity, especially for protection agains

181 Due to functionally distinct cell-mediated immunity, newborns and infants are highly

182 mechanisms by which C. gattii might subvert cell-mediated immunity, we found that C. gattii failed t

183 T cells is vital for sustaining long-lived T cell-mediated immunity.

184 eneration of T-helper type 1 cells, favoring cell-mediated immunity.

185 n of targets associated with activation of T cell-mediated immunity.

186 rologous protection, indicating a role for T cell-mediated immunity.

187 n of tolerance and foreign Ags to initiate T cell-mediated immunity.

188 terleukin-17A, indicating that PNAG promoted cell-mediated immunity.

189 is a co-inhibitory molecule that modulates T cell-mediated immunity.

190 rus neutralizing antibodies, as well as weak cell-mediated immunity.

191 ntranasal route and induced both humoral and cell-mediated immunity.

192 nd few studies have included measurements of cell-mediated immunity.We assessed the effects of diets

193 35, and IL-10, contributes to apoptotic Treg-cell-mediated immunosuppression.

194 nd TGF-beta have also been associated with B cell-mediated immunosuppression.

195 ligand pairs and are thought to allow for NK cell-mediated immunosurveillance of stressed or infected

196 death-1 (PD-1) ligand 1 (PD-L1) to subvert T-cell-mediated immunosurveillance.

197 lockers are not only applicable to enhance T cell-mediated immunotherapy, but also to restore the tum

198 o best predict the presence of intrathecal T-cell mediated inflammation.

199 Immune cell-mediated inflammation is an essential process for m

200 athy, accumulation of activated T cells, and cell-mediated inflammation of the skin and lung.

201 lenges commonly triggers pathological type 2 cell-mediated inflammation.

202 tic potential that can be used to treat mast cell-mediated inflammation.

203 ergic contact dermatitis (ACD) is a common T-cell mediated inflammatory skin condition, characterized

204 rs may be a novel therapeutic approach for T cell-mediated inflammatory disease.

205 s required for TH17 differentiation and TH17 cell-mediated inflammatory diseases.

206 Ocular infection with HSV causes a chronic T cell-mediated inflammatory lesion in the cornea.

207 by which mast cells (MCs) are activated in T cell-mediated inflammatory processes remains elusive.

208 ding to their activation in the context of T cell-mediated inflammatory processes.

209 sential for suppressing overactive dendritic cell-mediated inflammatory responses, thereby controllin

210 m Ag-specific unresponsiveness in a memory T cell-mediated inflammatory skin model.

211 ic deficits potentially impact neurogliaform cell mediated inhibition within the hippocampus and our

212 ing in the glomerular layer, but not granule-cell-mediated inhibition, reduces MC spike latency at we

213 d primarily through L1 neuron- and L2/L3 VIP-cell-mediated inhibitory and disinhibitory circuits.

214 Pdcd1 (PD-1) disruption augmented CAR T cell mediated killing of tumor cells in vitro and enhanc

215 The circuits triggered selective T cell-mediated killing of cancer cells, but not of normal

216 pairs DR5 activation-induced apoptosis and T cell-mediated killing of cancer cells.

217 hibition of HSP90 with ganetespib enhances T-cell-mediated killing of patient-derived human melanoma

218 tivity of many different tumors to Vdelta2 T-cell-mediated killing, the conditions defined here for s

219 mation applied to cone signals is horizontal-cell-mediated lateral inhibition, which imparts a spatia

220 The novel prodrug also induced T cell mediated leukemia cell lysis.

221 Concanavalin A (ConA) causes immune cell-mediated liver damage, but the contribution of resi

222 argeting the V1V2 domain induce up to 60% NK cell mediated lysis of HIV-1 infected PBMCs in a physiol

223 , with NKG2D and DNAM-1 playing a role in NK cell-mediated lysis of infected cells.

224 cell surface which subsequently inhibits NK-cell-mediated lysis.

225 ta suggest a critical role for talin in Treg cell-mediated maintenance of immune homeostasis.

226 abscess formation via a WTA-dependent and T-cell-mediated mechanism than S. aureus strains with a WT

227 plications for the management of cancer stem cell-mediated melanoma progression.

228 mucosal immunity and systemic B cell- and T cell-mediated memory responses.

229 Con A hepatitis is regarded as a T cell-mediated model of acute liver injury.

230 the serial signaling events, we studied a T-cell-mediated model of EAE combining in vivo two-photon

231 CD4 T cell-mediated MVEC death involves in TNFalpha, FasL and

232 Alloreactive CD4 T cell-mediated MVEC death involves TNFalpha, Fas ligand (

233 suggests blood-brain barrier breakdown and T-cell-mediated neuropathology as potential underpinnings

234 notype and regeneration and promotes Schwann-cell-mediated neurotrophic support in models of peripher

235 tion was via endogenous cKit(+) cardiac stem cell-mediated new myocyte formation.

236 o biological role of m(6)A modification in T-cell-mediated pathogenesis and reveals a novel mechanism

237 could be exploited to prevent and/or treat T cell-mediated pathologies, including transplant rejectio

238 Antibody-dependent cell-mediated phagocytosis (ADCP) was rarely detected du

239 cytotoxicity (CDCC) and complement-dependent cell-mediated phagocytosis (CDCP) by immunological effec

240 RATIONALE: Aortic valve disease is a cell-mediated process without effective pharmacotherapy.

241 g commensal in mice that induces gammadeltaT cell-mediated protection from opportunistic infection.

242 tive senescence, decline in muscle satellite cell-mediated regeneration coincides with activation of

243 ontribution of epigenetic regulation in stem cell-mediated regeneration of adult tissues.

244 Our study highlights strategies for stem cell-mediated regeneration that may be conserved in othe

245 ntly higher in PVAN biopsies compared with T cell-mediated rejection (TCMR) (1.42 +/- 0.20 and 0.69 +

246 Although both polyomavirus infection and T cell-mediated rejection (TCMR) are characterized by tubu

247 hat segregated samples based on concurrent T cell-mediated rejection (TCMR) identified overlapping me

248 within the descriptions of chronic active T cell-mediated rejection (TCMR) or chronic ABMR.

249 cid-plasma samples of 64 patients (18 AMR, 8 cell-mediated rejection [CMR], 38 no rejection in desens

250 itis B virus, hepatitis C virus, and acute T cell-mediated rejection have redirected focus on long-te

251 was associated with an increased risk for T cell-mediated rejection or antibody-mediated rejection (

252 en biopsy specimens showing any rejection (T cell-mediated rejection or antibody-mediated rejection [

253 s did not show upregulation of T cell- and B cell-mediated rejection pathways.

254 type IA), and 0.3% in controls (P=0.05 for T cell-mediated rejection types >/=IB versus controls).

255 ing a critical role for IL-6 in mediation of cell-mediated rejection, antibody-mediated rejection, an

256 Functionally, this CD8(+) T cell-mediated reorganization of the local DC network all

257 functions are expressed that counteract the cell-mediated repression.

258 Its genetic blockade unleashes NK-cell-mediated resistance to hepatic carcinogenesis, haem

259 ells, and NK cells to provide help for CD8 T cell-mediated response to B cell-derived exosomes.

260 e of autoantigens, can lead to an adaptive T cell-mediated response.

261 l type of checkpoint inhibitor to enhance NK-cell-mediated responses against cancer and infection.

262 d Tfh cells is important to induce effective cell-mediated responses and provide optimal help for ant

263 ne induces high-level virus-specific Ab- and cell-mediated responses in neonates that result in incre

264 ts during the acute phase of IM, whereas the cell-mediated responses, even when they resembled those

265 ry cytokines with a concordant blockade of T cell-mediated responses.

266 These results indicate that AP4 integrates T-cell-mediated selection and sustained expansion of GC B

267 mportant applications for the treatment of T-cell-mediated skin inflammatory diseases.

268 full-dose treatment, a strong reduction in T-cell-mediated skin symptoms was observed which reappeare

269 on was observed in 22 (29.3%) patients (17 T cell-mediated subclinical rejection [sc-TCMR], 5 antibod

270 of the pathogenesis of autoantibody-induced, cell-mediated subepidermal blistering diseases and ident

271 The cytokine IL-21 was able to overcome TFR cell-mediated suppression and inhibited TFR cells and st

272 ssive loss of both protective immunity and T cell-mediated suppression, thereby conferring susceptibi

273 By determining mechanisms of TFR cell-mediated suppression, we have identified methods fo

274 comitantly enhance Th2 cells and limit T reg cell-mediated suppression.

275 ally challenged with PN, they exhibited mast-cell-mediated systemic anaphylaxis, as indicated by hypo

276 Additionally, CD4+ Th2 cells mediated the antitumor effects of TSLP, challengin

277 Unfortunately, application of CAR T cell-mediated therapy for solid tumors has so far been d

278 ogenesis in PIDs, and developments in immune cell-mediated therapy to treat disorders associated with

279 +) T cell depletions confirmed that CD8(+) T cells mediated this protection.

280 spase-independent apoptosis in neuroblastoma cells mediated through modulation of AIF, ATM, and gamma

281 CD4(+) T cell-mediated tissue damage and subsequent IL-33 release

282 homeostasis; however, a role for UTX in stem cell-mediated tissue regeneration is unknown.

283 uvants activate innate immune cells, promote cell-mediated transport of antigen to lymphoid tissues,

284 over a potent intracellular checkpoint in NK cell-mediated tumor immunity and suggest possibilities f

285 use this particular pathway to inhibit CD8 T-cell-mediated tumor immunity.

286 highlighting a cross-talk between IgE and T cell-mediated tumor immunosurveillance.

287 mouse model of MB results in potent CD4(+) T cell-mediated tumor rejection.

288 o-repressors, along with immune escape via T-cell-mediated tumor surveillance.

289 G mice previously engrafted with myeloma, SE cells mediated tumor rejection without inducing xenogene

290 % reflect the absence of active rejection (T cell-mediated type >/=IB or ABMR) and levels >1% indicat

291 1.2% (T cell-mediated types >/=IB), 0.2% (T cell-mediated type IA), and 0.3% in controls (P=0.05 for

292 Median dd-cfDNA was 2.9% (ABMR), 1.2% (T cell-mediated types >/=IB), 0.2% (T cell-mediated type I

293 ed PDA aggressiveness was dependent on tumor cell-mediated uptake of CAF-derived ANXA6+ EVs carrying

294 T cells will be critical to the success of a cell-mediated vaccine against liver-stage malaria.

295 yzed their potential in identifying severe T cell-mediated vascular rejection (TCMVR) (Banff 4-II/III

296 The pathogenetic immune mechanisms involved (cell-mediated versus humoral) remain incompletely known.

297 nfiltration of protective ASC occurs after T cell-mediated viral control and is preceded by accumulat

298 comparisons identified a set of Ab-dependent cell-mediated viral inhibition and phagocytosis assays t

299 t cellular cytotoxicity (ADCC), Ab-dependent cell-mediated viral inhibition, and Ab-dependent cellula

300 host huTreg to xenogeneic grafts to regulate cell-mediated xenograft rejection including NK cell resp