ライフサイエンスコーパス: cell-mediated cytotoxicity

1 K cell activation through antibody-dependent cell-mediated cytotoxicity.

2 that lacks functionality for complement- and cell-mediated cytotoxicity.

3 ross-linked with antibodies it suppressed NK cell-mediated cytotoxicity.

4 ell activation, proliferation, and bystander cell-mediated cytotoxicity.

5 -RasV12 increased sensitivity of cells to NK cell-mediated cytotoxicity.

6 sera, reducing to near zero complement- and cell-mediated cytotoxicity.

7 ack NK cells and showed severely impaired NK cell-mediated cytotoxicity.

8 he exocytic events required for effective NK cell-mediated cytotoxicity.

9 S response also directly suppressed CD8(+) T-cell-mediated cytotoxicity.

10 nces rituximab-mediated, antibody-dependent, cell-mediated cytotoxicity.

11 ulation of these secretory events leading to cell-mediated cytotoxicity.

12 cells in vitro and caused their Ab-dependent cell-mediated cytotoxicity.

13 ptors, is implicated in the activation of NK cell-mediated cytotoxicity.

14 a 100-fold improvement in antibody-dependent cell-mediated cytotoxicity.

15 ituximab binding, and rituximab-dependent NK cell-mediated cytotoxicity.

16 d function of T regulatory cells may enhance cell-mediated cytotoxicity.

17 o bind FcgammaRIIIA and trigger Ab-dependent cell-mediated cytotoxicity.

18 nd defects in T-regulatory cells may enhance cell-mediated cytotoxicity.

19 L/TRAIL), three key mediators of immunologic cell-mediated cytotoxicity.

20 s downstream of CRACC/EAT-2 implicated in NK cell-mediated cytotoxicity.

21 -opsonized particles, and antibody-dependent cell-mediated cytotoxicity.

22 d decreases susceptibility to natural killer cell-mediated cytotoxicity.

23 lls with poly(I:C) significantly augments NK cell-mediated cytotoxicity.

24 scFv-Fc did not enhance antibody-dependent cell-mediated cytotoxicity.

25 ling of apoptosis, complement activation and cell-mediated cytotoxicity.

26 e xenograft rejection and antibody-dependent cell-mediated cytotoxicity.

27 mplement-dependent and/or antibody-dependent cell-mediated cytotoxicity.

28 by a reduction in susceptibility to human NK cell-mediated cytotoxicity.

29 tumor cell resistance to natural killer (NK) cell-mediated cytotoxicity.

30 t rejection, interferon-gamma production and cell-mediated cytotoxicity.

31 ally modified cells resist Ab-independent NK cell-mediated cytotoxicity.

32 d to play a role in tumor cell resistance to cell-mediated cytotoxicity.

33 susceptibility of porcine cells to human NK cell-mediated cytotoxicity.

34 protect xenogeneic endothelial cells from NK cell-mediated cytotoxicity.

35 re either protected or are susceptible to NK cell-mediated cytotoxicity.

36 lipid rafts and the subsequent generation of cell-mediated cytotoxicity.

37 le of death receptor-induced apoptosis in NK cell-mediated cytotoxicity.

38 ar IFN-gamma synthesis and markedly enhanced cell-mediated cytotoxicity.

39 be a positive regulatory role for 3BP2 in NK cell-mediated cytotoxicity.

40 P-1-mediated gene transcription and enhances cell-mediated cytotoxicity.

41 ators of opsonophagocytosis and Ab-dependent cell-mediated cytotoxicity.

42 ion critically influences the development of cell-mediated cytotoxicity.

43 1 resensitizes the K5-expressing cells to NK cell-mediated cytotoxicity.

44 uence, K5 expression drastically inhibits NK cell-mediated cytotoxicity.

45 They have no effect on NK cell-mediated cytotoxicity.

46 terferon-gamma production and enhancement of cell-mediated cytotoxicity.

47 in vitro and caused their antibody-dependent cell-mediated cytotoxicity.

48 assessed the roles of p38 and JNK MAPK in NK cell-mediated cytotoxicity.

49 ucers and did not inhibit antibody-dependent cell-mediated cytotoxicity.

50 complement-mediated, and antibody-dependent cell-mediated cytotoxicity.

51 aptor protein for the regulation of human NK cell-mediated cytotoxicity.

52 omplement as well as to mediate Ab-dependent cell-mediated cytotoxicity.

53 eptibility of CMV-infected fibroblasts to NK cell-mediated cytotoxicity.

54 omplex (MHC) class I peptides and inhibit NK-cell-mediated cytotoxicity.

55 eir protective effects required Ab-dependent cell-mediated cytotoxicity.

56 the other dependent upon CD95 (Fas), effect cell-mediated cytotoxicity.

57 te participants in the granzyme A pathway of cell-mediated cytotoxicity.

58 LRG1 expression; proliferation; and CD4(+) T cell-mediated cytotoxicity.

59 esumably NK cell-resistant tumor cells to NK cell-mediated cytotoxicity.

60 BB signaling can increase antibody-dependent cell-mediated cytotoxicity.

61 e the ability of myeloma cells to trigger NK cell-mediated cytotoxicity.

62 chanisms likely involving antibody-dependent cell-mediated cytotoxicity.

63 Arl8b), as a critical factor required for NK cell-mediated cytotoxicity.

64 nducing apoptosis through antibody-dependent cell-mediated cytotoxicity.

65 es RAE-1 expression and susceptibility to NK cell-mediated cytotoxicity.

66 ensed NK cells to mediate antibody-dependent cell-mediated cytotoxicity.

67 /HER3 enhanced the NKG2D-MICA/B-dependent NK cell-mediated cytotoxicity.

68 al forms, potent in vitro antibody-dependent cell-mediated cytotoxicity (0.1-0.3 mug/ml EC50), and hi

69 vitro, XmAb5574 enhanced antibody-dependent cell-mediated cytotoxicity 100-fold to 1,000-fold relati

70 Antibody-dependent cell-mediated cytotoxicity, a key effector function for

71 of cellular mechanisms such as Ab-dependent cell-mediated cytotoxicity, Ab-dependent cellular phagoc

72 not males were correlated with Ab-dependent cell-mediated cytotoxicity activity against gp120 target

73 n the cotton rat and that antibody-dependent cell-mediated cytotoxicity activity can significantly en

74 cell assay, and moderate antibody-dependent, cell-mediated cytotoxicity activity was demonstrated.

75 tryptophan at K326 debilitates Ab-dependent cell-mediated cytotoxicity activity.

76 which resulted in strong antibody-dependent cell-mediated cytotoxicity activity.

77 of antibodies with potent antibody-dependent cell-mediated cytotoxicity activity.

78 e switching for improved antibody-dependent, cell-mediated cytotoxicity activity.

79 d a means to modulate the antibody-dependent cell-mediated cytotoxicity (ADCC) activity of a humanize

80 g and function, including antibody-dependent cell-mediated cytotoxicity (ADCC) activity, at levels si

81 affinity by BIACORE, for antibody-dependent cell-mediated cytotoxicity (ADCC) and complement-mediate

82 valuated functionally by antibody-dependent, cell-mediated cytotoxicity (ADCC) and for neutralization

83 the relationship between antibody-dependent cell-mediated cytotoxicity (ADCC) and virus neutralizati

84 f virus-infected cells by antibody-dependent cell-mediated cytotoxicity (ADCC) are limited by the num

85 ency virus (HIV)-specific antibody-dependent cell-mediated cytotoxicity (ADCC) are present in the cer

86 ulticolor flow cytometry, antibody-dependent cell-mediated cytotoxicity (ADCC) assay, and immunohisto

87 transfer experiments and antibody-dependent cell-mediated cytotoxicity (ADCC) assays indicate that t

88 Moreover, antibody-dependent cell-mediated cytotoxicity (ADCC) assays revealed that t

89 umor cell killing such as antibody-dependent cell-mediated cytotoxicity (ADCC) by isolated monocytes,

90 Antibody-dependent cell-mediated cytotoxicity (ADCC) by NK cells contribute

91 Interestingly, Ab-dependent cell-mediated cytotoxicity (ADCC) by NK cells, monocytes

92 Antibody-dependent cell-mediated cytotoxicity (ADCC) by non-neutralizing an

93 or cell susceptibility to antibody-dependent cell-mediated cytotoxicity (ADCC) by selective desialyla

94 for cancer treatment via antibody-dependent cell-mediated cytotoxicity (ADCC) has been little studie

95 ouse bone marrow produced antibody-dependent cell-mediated cytotoxicity (ADCC) in cell cultures expre

96 immune serum, suggesting antibody-dependent cell-mediated cytotoxicity (ADCC) in F. novicida Deltafo

97 influence the outcome of antibody-dependent cell-mediated cytotoxicity (ADCC) in vitro and in animal

98 ecent studies demonstrate antibody-dependent cell-mediated cytotoxicity (ADCC) is one of the modes of

99 humoral immune response, antibody-dependent cell-mediated cytotoxicity (ADCC) may be a functioning m

100 how they achieve a higher antibody-dependent cell-mediated cytotoxicity (ADCC) potency than native im

101 uated the kinetics of the antibody-dependent cell-mediated cytotoxicity (ADCC) response during acute

102 able to mediate phagocytosis or Ab-dependent cell-mediated cytotoxicity (ADCC) through Fc gamma RI, F

103 XmAbCD40 increased antibody-dependent cell-mediated cytotoxicity (ADCC) up to 150-fold relativ

104 ER3, and mediate enhanced antibody-dependent cell-mediated cytotoxicity (ADCC) via glycoengineering o

105 complement-mediated killing and Ab-dependent cell-mediated cytotoxicity (ADCC) were compared between

106 ntaneous cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC) when triggered by ritu

107 of HIV-infected cells to antibody-dependent cell-mediated cytotoxicity (ADCC), and conversely that R

108 ully understood, although antibody-dependent cell-mediated cytotoxicity (ADCC), complement-dependent

109 of antibodies, including antibody-dependent cell-mediated cytotoxicity (ADCC), in prevention of huma

110 f virus-infected cells by antibody-dependent cell-mediated cytotoxicity (ADCC), we show that substitu

111 Antibody-dependent cell-mediated cytotoxicity (ADCC), which is largely medi

112 ed CML LSPCs by selective antibody-dependent cell-mediated cytotoxicity (ADCC)-facilitated lysis of C

113 ovirus neutralization and antibody-dependent cell-mediated cytotoxicity (ADCC).

114 by antibodies to mediate antibody-dependent cell-mediated cytotoxicity (ADCC).

115 rance of target cells via antibody dependent cell-mediated cytotoxicity (ADCC).

116 3 signaling and eliciting antibody-dependent cell-mediated cytotoxicity (ADCC).

117 tumor protection through antibody-dependent cell-mediated cytotoxicity (ADCC).

118 ls neuroblastoma cells by antibody-dependent cell-mediated cytotoxicity (ADCC).

119 ptotic effects as well as antibody-dependent cell-mediated cytotoxicity (ADCC).

120 on of cytokines enhancing antibody-dependent cell-mediated cytotoxicity (ADCC).

121 ication and resistance to antibody-dependent cell-mediated cytotoxicity (ADCC).

122 mediated cytotoxicity and antibody-dependent cell-mediated cytotoxicity (ADCC).

123 t cytotoxicity (CDC), and antibody-dependent cell-mediated cytotoxicity (ADCC).

124 cted women participate in antibody-dependent cell-mediated cytotoxicity (ADCC).

125 ing in part from enhanced antibody-dependent cell-mediated cytotoxicity (ADCC).

126 t either promote or block antibody-dependent cell-mediated cytotoxicity (ADCC).

127 e virus-infected cells by antibody-dependent cell-mediated cytotoxicity (ADCC).

128 ate immune system such as antibody-dependent cell-mediated cytotoxicity (ADCC).

129 phonuclear cells (PMN) to exert Ab-dependent cell-mediated cytotoxicity (ADCC).

130 referentially targeted by antibody-dependent cell-mediated cytotoxicity (ADCC).

131 nt cytotoxicity (CDC) and antibody-dependent cell-mediated cytotoxicity (ADCC).

132 ating receptor that facilitates Ab-dependent cell-mediated cytotoxicity (ADCC).

133 Cell-mediated cytotoxicity against chondrocytes was eval

134 as been shown to be sufficient to trigger NK cell-mediated cytotoxicity against Fc receptor-bearing c

135 Because superantigens can direct cell-mediated cytotoxicity against MHC II-positive cells

136 T cell-mediated cytotoxicity against Mycobacterium tubercu

137 n-like transcript 1 (LLT1) interaction in NK cell-mediated cytotoxicity against normal human articula

138 rmore, XmAb5574 conferred antibody-dependent cell-mediated cytotoxicity against patient-derived acute

139 ggest methods utilizing HLA-G to overcome NK cell-mediated cytotoxicity against porcine endothelial c

140 CD8+ T cell-mediated and natural killer (NK) cell-mediated cytotoxicity against renal tubular epithel

141 e of GJs in NK cell activation by DCs and NK cell-mediated cytotoxicity against tumor cells remains u

142 in NK cells leads to increased Ab-dependent cell-mediated cytotoxicity and "natural cytotoxicity," t

143 ity to lyse human tumor cells by both direct cell-mediated cytotoxicity and Ab-dependent cellular cyt

144 rat Crry expressed on tumor cells has on rat cell-mediated cytotoxicity and antibody-dependent cell-m

145 activation of NK cells, thereby enhancing NK cell-mediated cytotoxicity and antibody-dependent cellul

146 we examined the potential contribution of T-cell-mediated cytotoxicity and apoptosis to mucosal clea

147 The antibody-dependent cell-mediated cytotoxicity and apoptotic activity of J6M

148 nctions by regulatory T cells may facilitate cell-mediated cytotoxicity and autoreactivity.

149 ally capable of recruiting host Ab-dependent cell-mediated cytotoxicity and complement-dependent cyto

150 render the Fc unable to direct Ab-dependent cell-mediated cytotoxicity and complement-dependent cyto

151 fector functions, such as antibody-dependent cell-mediated cytotoxicity and complement-dependent cyto

152 in the IgG format induced antibody-dependent cell-mediated cytotoxicity and complement-dependent-cyto

153 ossibly SHP-2, resulting in inhibition of NK cell-mediated cytotoxicity and cytokine expression.

154 NK cells and LLT1 on target cells inhibit NK cell-mediated cytotoxicity and cytokine production and c

155 n, the mechanism by which DNAM-1 controls NK cell-mediated cytotoxicity and cytokine production was e

156 vation of NF-kappaB that lead to impaired NK cell-mediated cytotoxicity and cytokine production.

157 by in vitro assays measuring KIR3DS1-induced cell-mediated cytotoxicity and cytokine production.

158 function, we assessed the role of ICOS in NK cell-mediated cytotoxicity and cytokine production.

159 lting in inhibition of natural-killer- and T-cell-mediated cytotoxicity and cytokine secretion.

160 N-glycans and had better antibody-dependent cell-mediated cytotoxicity and effector cell receptor bi

161 antibodies weakly induced antibody-dependent cell-mediated cytotoxicity and enhanced induction in the

162 es not greatly influence NK-cell or CD8(+) T-cell-mediated cytotoxicity and has minimal impact on cyt

163 re, we analyzed the involvement of ERK in NK cell-mediated cytotoxicity and IFN-gamma expression indu

164 PGE(2) significantly suppressed NK cell-mediated cytotoxicity and IFN-gamma production at t

165 G2D receptors, and decreases NKG2D-dependent cell-mediated cytotoxicity and IFN-gamma production.

166 dase inhibition, in vitro antibody-dependent cell-mediated cytotoxicity and in vivo protection agains

167 on, generalized but reversible defects in NK cell-mediated cytotoxicity and mild CD8(+) T cell defect

168 In spite of T cell-mediated cytotoxicity and persistent, clonally expa

169 ctor function of CD8 T cells is mediated via cell-mediated cytotoxicity and production of cytokines l

170 adelta T lymphocytes in the regulation of NK cell-mediated cytotoxicity and provide rationale for the

171 fector cells of the immune system to enhance cell-mediated cytotoxicity and suggest investigation int

172 These data further confirm the importance of cell-mediated cytotoxicity and suggest that additional c

173 kinase to DAP10 could not by itself trigger cell-mediated cytotoxicity and that binding of an interm

174 nstrate an association between pretransplant cell-mediated cytotoxicity and the occurrence of chronic

175 th sequence homology for myosin, elicit both cell-mediated cytotoxicity and tumor necrosis factor-alp

176 suggest the importance of antibody-dependent cell-mediated cytotoxicity and/or apoptosis induction vi

177 ented anti-mouse mixed lymphocyte responses, cell-mediated cytotoxicity, and antibody production.

178 t-dependent cytotoxicity, antibody-dependent cell-mediated cytotoxicity, and antibody-dependent cellu

179 due to increased resistance to Ab-dependent cell-mediated cytotoxicity, and does not trigger cytopat

180 as been shown to downregulate proliferation, cell-mediated cytotoxicity, and IFN-gamma production, as

181 ects in counter-regulatory functions enhance cell-mediated cytotoxicity, and interventions that promi

182 noglobulin G1 binding and antibody-dependent cell-mediated cytotoxicity, and may therefore influence

183 to FcgammaRIIIa, enhanced antibody-dependent cell-mediated cytotoxicity, and more than doubled the me

184 ects in counter-regulatory functions enhance cell-mediated cytotoxicity, and pharmacological interven

185 related to T-cell activation, natural killer cell-mediated cytotoxicity, and programmed cell death.

186 intracellular signaling, antibody-dependent cell-mediated cytotoxicity, and rapid target internaliza

187 N-alpha and -beta) are potent inducers of NK cell-mediated cytotoxicity, and that NK cells are import

188 es in human T cell activation/proliferation, cell-mediated cytotoxicity, and volume regulation and is

189 CD4(+) T-cell-mediated apoptosis or CD8(+) T-cell-mediated cytotoxicity as being critical to the clea

190 their ability to support antibody-dependent cell-mediated cytotoxicity as demonstrated with an anti-

191 endent mechanisms leaves Fas/FasL-dependent, cell-mediated cytotoxicity as the major pathway for CTL-

192 mediated lysis assay, and antibody-dependent cell-mediated cytotoxicity assay.

193 so shown for both mAbs in antibody-dependent cell-mediated cytotoxicity assay.

194 Despite this, reverse antibody-dependent cell-mediated cytotoxicity assays showed potent degranul

195 ogous normal cells are not susceptible to NK cell-mediated cytotoxicity because they express inhibito

196 hways not only are the major mechanisms of T cell-mediated cytotoxicity but also are involved in home

197 The antibodies elicited cell-mediated cytotoxicity, but little neutralizing acti

198 0 in lipid rafts, affects antibody-dependent cell-mediated cytotoxicity, but not complement-dependent

199 There was dose-dependent inhibition of LAK cell-mediated cytotoxicity, but this effect was not seen

200 ic unresponsiveness developed as assessed by cell-mediated cytotoxicity by blood mononuclear cells in

201 -22 decreased epithelial susceptibility to T cell-mediated cytotoxicity by inhibiting the IFN-gamma-i

202 Therefore, 3BP2 regulates NK cell-mediated cytotoxicity by mobilizing key downstream

203 negative Rac1 inhibits the development of NK cell-mediated cytotoxicity by two mechanisms: (a) conjug

204 NK cell activation and NK cell-mediated cytotoxicity can be a direct barrier to th

205 cells that are comparatively resistant to NK cell-mediated cytotoxicity caused by the paucity of othe

206 therapeutic antibodies, complement-dependent cell-mediated cytotoxicity (CDCC) and complement-depende

207 eased cell killing by a complement-dependent cell-mediated cytotoxicity (CDCC) mechanism.

208 esting IgM functions by complement-dependent cell-mediated cytotoxicity (CDCC), a mechanism thought t

209 ion, resulting in greater antibody-dependent cell-mediated cytotoxicity compared with IL-21 and/or an

210 re for the enhancement of antibody-dependent cell-mediated cytotoxicity, complement-dependent cytotox

211 nulation pathway, but not antibody-dependent cell-mediated cytotoxicity, contribute to the superior c

212 Virtually all of the measurable cell-mediated cytotoxicity delivered by cytotoxic T lymp

213 ton, MA) from 1983 to 1995 to assess whether cell-mediated cytotoxicity, determined in vitro and meas

214 ated in an in vitro wound repair model and T cell-mediated cytotoxicity experiments.

215 killer and lymphokine-activated killer (LAK) cell-mediated cytotoxicity for G-CSF-mobilized effector

216 t depletes eosinophils by antibody-dependent cell-mediated cytotoxicity, for patients with severe, un

217 ressing cells were resistant to Ab-dependent cell-mediated cytotoxicity, formed no syncytia, and neit

218 Although CD4 T cell-mediated cytotoxicity has been reported in multiple

219 Natural cytotoxicity, Ab-dependent cell-mediated cytotoxicity, IFN-gamma production, and TN

220 to be capable of inducing antibody-dependent cell-mediated cytotoxicity in ABCB5+ MMIC, exerted tumou

221 me B (GzmB) is a serine protease involved in cell-mediated cytotoxicity in conjunction with the pore-

222 The role of NK cell-mediated cytotoxicity in controlling tumor growth w

223 data demonstrate a dominant role of CD4(+) T cell-mediated cytotoxicity in plasmid DNA vaccine antige

224 variants demonstrated no antibody-dependent cell-mediated cytotoxicity in vitro against Daudi cells

225 lular phagocytosis and/or antibody-dependent cell-mediated cytotoxicity in vitro Our antibodies, spec

226 r compound sensitized lymphomas to dendritic cell-mediated cytotoxicity in vitro.

227 ent to induce a substantial impairment of NK cell-mediated cytotoxicity in vitro.

228 but not rat CD59, on MCF7 cells inhibits rat cell-mediated cytotoxicity in vitro.

229 survival and the serum-mediated Ab-dependent cell-mediated cytotoxicity in vitro.

230 T cells as well as T cell and natural killer cell-mediated cytotoxicity in vitro.

231 f Ebola virus and mediate antibody-dependent cell-mediated cytotoxicity in vitro.

232 contributions of these effector molecules to cell-mediated cytotoxicity in vivo in a GvHD model.

233 IFN-gamma-deficient mice, we show that CD4 T cell-mediated cytotoxicity in vivo is not dependent on I

234 is a potent regulator of antibody-dependent cell-mediated cytotoxicity in vivo, modulating the activ

235 ammaRIIB showed much more antibody-dependent cell-mediated cytotoxicity; in contrast, mice deficient

236 Cell-mediated cytotoxicities increased against Daudi cel

237 cell clearance, NKG2D- or antibody-dependent cell-mediated cytotoxicity-induced tumor cell cytotoxici

238 2B4 activates NK cell mediated cytotoxicity, induces secretion of IFN-gam

239 signaling inhibition with antibody-dependent cell-mediated cytotoxicity induction and results in supe

240 regulate the magnitude of antibody-dependent cell-mediated cytotoxicity induction.

241 Stimulation of NK cell-mediated cytotoxicity involves the coupling of prox

242 One of the two primary mechanisms used in cell-mediated cytotoxicity is the Fas/FasLigand system.

243 Natural killer (NK) cell-mediated cytotoxicity is triggered by multiple acti

244 Nanowell Grids to analyze antibody-dependent cell-mediated cytotoxicity kinetics of thousands of indi

245 and that TRAIL deficiency decreases CD8(+) T cell-mediated cytotoxicity, leading to more severe influ

246 ed following a decline in antibody-depending cell-mediated cytotoxicity-like antibodies.

247 growth factor receptors, antibody-dependent cell-mediated cytotoxicity) limit efficacy.

248 ells is associated with extraarticular RA, T cell-mediated cytotoxicity may be particularly important

249 of self proteins, GrB-cleaved TAL-specific T cell-mediated cytotoxicity may contribute to the progres

250 ndent mechanisms, such as antibody-dependent cell-mediated cytotoxicity, may be involved in the in vi

251 y both complement-dependent and Ab-dependent cell-mediated cytotoxicity mechanisms; the CD8+ cells do

252 Cell-mediated cytotoxicity might be key to controlling i

253 Anti-MUC1 antibody-dependent cell-mediated cytotoxicity of Du145 by human peripheral

254 mplement-dependent cytolysis or Ab-dependent cell-mediated cytotoxicity of immortalized human hepatoc

255 Importantly, NK cell-mediated cytotoxicity of target cells could also in

256 ulations to determine the effects of donor T cell-mediated cytotoxicity on engraftment.

257 extent, IMC-NC7 initiated antibody-dependent cell-mediated cytotoxicity on FLT3-expressing cells.

258 and therefore does not mediate Ab-dependent cell-mediated cytotoxicity or modulation/loss of CD4 fro

259 neutralization activity, antibody-dependent cell-mediated cytotoxicity, or HIV-1 envelope-specific I

260 a by NK cells in the context of Ab-dependent cell-mediated cytotoxicity (p = 0.039) and increased deg

261 ng genes, including eight involved in the NK cell-mediated cytotoxicity pathway, impairs lymphokine-a

262 Cell-mediated cytotoxicity plays an important role in th

263 Antibody-dependent cell-mediated cytotoxicity plays an important role in th

264 In contrast, antibody-dependent cell-mediated cytotoxicity produced by natural killer ce

265 by downregulation of cellular ligands for NK cell-mediated cytotoxicity receptors.

266 es ICAM-1 and B7-2, which are ligands for NK cell-mediated cytotoxicity receptors.

267 ing molecules involved in the development of cell-mediated cytotoxicity remain poorly defined.

268 esponse was restored, whereas donor-specific cell-mediated cytotoxicity remained suppressed.

269 d IgG3 subclass mediating antibody-dependent cell-mediated cytotoxicity, seem to play a predominant r

270 gests Chok is a single locus that affects NK cell-mediated cytotoxicity similar to other NKC loci tha

271 Through antibody-dependent, cell-mediated cytotoxicity, such an antibody could still

272 BB-94; however, BB-94 has no effect on A-NK cell-mediated cytotoxicity, suggesting that matrix metal

273 iciency disorder characterized by defects in cell-mediated cytotoxicity that results in fever, hepato

274 receptor of the CD2 family that triggers NK cell-mediated cytotoxicity through an undefined signalin

275 ndergoing mAb therapy via antibody-dependent cell-mediated cytotoxicity, thus explaining the potent "

276 were capable of inducing antibody-dependent cell-mediated cytotoxicity to autologous and allogeneic

277 T-cell-mediated cytotoxicity toward ganglion cells may boo

278 hown to elicit a level of antibody-dependent cell-mediated cytotoxicity toward human neuroblastoma ce

279 n vitro analyses confirmed the presence of T cell-mediated cytotoxicity toward the breast cancer cell

280 s of kindlin-3 has a pronounced effect on NK cell-mediated cytotoxicity triggered by single activatin

281 nhibition of signaling pathways, but also by cell-mediated cytotoxicity triggered by the infused TA-t

282 tion of each of these exchange factors to NK cell-mediated cytotoxicity using mice lacking one, two,

283 In vitro effector-cell mediated cytotoxicity was observed at picomolar con

284 t of ERK in the regulation of Ca2+-dependent cell-mediated cytotoxicity was confirmed, using a geneti

285 NK cell-mediated Ab-dependent cell-mediated cytotoxicity was limited by viral Ag avail

286 However, only marginal T cell-mediated cytotoxicity was observed by these splenoc

287 The spontaneous NK-cell-mediated cytotoxicity was primarily perforin based,

288 In this study, LIR-1(+) NKL cell-mediated cytotoxicity was shown to be inhibited by

289 ther investigate the function of NKLAM in NK cell-mediated cytotoxicity, we generated, by gene target

290 thways, activation of apoptosis and effector-cell-mediated cytotoxicity, we show here that engagement

291 tokine-cytokine receptor interactions and NK cell-mediated cytotoxicity were down-regulated in cKO de

292 yeloid effector cells for antibody-dependent cell-mediated cytotoxicity, were similar between wild-ty

293 CD226 activates natural killer (NK) cell-mediated cytotoxicity, whereas TIGIT reportedly cou

294 on of IgG via CD16a and execute Ab-dependent cell-mediated cytotoxicity, which is critical for the ef

295 implications as an approach to overcoming NK cell-mediated cytotoxicity, which may be an obstacle to

296 ontrast, Cbl-b deficiency minimally affected cell-mediated cytotoxicity, which requires limited engag

297 nd blocked NMO-IgG-dependent complement- and cell-mediated cytotoxicity with IC(50) down to approxima

298 transplantation vasculopathy is initiated by cell-mediated cytotoxicity with its perpetuation facilit

299 m reduced by >95% CDC and antibody-dependent cell-mediated cytotoxicity, without impairment of NMO-Ig

300 latively competent for ITAM receptor-induced cell-mediated cytotoxicity, yet completely deficient for