ライフサイエンスコーパス: cell-mediated immunity

1 both neutralizing antibodies and protective cell mediated immunity.

2 d to provide convincing evidence of improved cell mediated immunity.

3 are generally focused on the enhancement of cell-mediated immunity.

4 oup of heritable deficiencies of humoral and cell-mediated immunity.

5 melanocytes in feathers appears to be due to cell-mediated immunity.

6 toma tumor were substantially dependent on T cell-mediated immunity.

7 articular focus on molecules associated with cell-mediated immunity.

8 nderlying conditions or diseases that impair cell-mediated immunity.

9 h Ft.LVS::Deltawzy elicited both humoral and cell-mediated immunity.

10 ol of pathogens or tumors usually requires T-cell-mediated immunity.

11 mechanism by which monocytic AML cells evade cell-mediated immunity.

12 optimize vaccines aimed at generating robust cell-mediated immunity.

13 ggests that neurotransmitters can modulate T cell-mediated immunity.

14 ecent studies show that cAMP also promotes T cell-mediated immunity.

15 were independent of hemodynamics and B and T cell-mediated immunity.

16 inflammatory response and efficiently induce cell-mediated immunity.

17 T cells is vital for sustaining long-lived T cell-mediated immunity.

18 d AIDS, at least in part, through effects on cell-mediated immunity.

19 tic anti-hDectin-1 mAb could elicit CD8(+) T cell-mediated immunity.

20 s played by TRAF3 in T cell activation and T cell-mediated immunity.

21 the in vivo functions of CRAC channels for T cell-mediated immunity.

22 important role in initiating or sustaining T cell-mediated immunity.

23 offers new opportunities to regulate CD8+ T cell-mediated immunity.

24 se chimeric vaccines induce both humoral and cell-mediated immunity.

25 auses disease in individuals with suppressed cell-mediated immunity.

26 eneration of T-helper type 1 cells, favoring cell-mediated immunity.

27 t are known to stimulate protective CD8(+)-T-cell-mediated immunity.

28 des, and elicit antigen-specific humoral and cell-mediated immunity.

29 and identifies a novel correlate of CD8(+) T cell-mediated immunity.

30 designing DENV-specific vaccines that induce cell-mediated immunity.

31 ation of B memory cells, and strong Th1-type cell-mediated immunity.

32 cis-UCA suppresses cell-mediated immunity.

33 or prevent the priming of robust protective cell-mediated immunity.

34 n of targets associated with activation of T cell-mediated immunity.

35 rrelated with classical measures of CD8(+)-T-cell-mediated immunity.

36 stems, of Ag-presentation for stimulation of cell-mediated immunity.

37 cines and therapeutics designed to support T-cell-mediated immunity.

38 rologous protection, indicating a role for T cell-mediated immunity.

39 ty skin test responses, an in vivo marker of cell-mediated immunity.

40 evolutionized our current understanding of T cell-mediated immunity.

41 pathogen containment and in shaping acquired cell-mediated immunity.

42 ion, disease and death can be prevented by T cell-mediated immunity.

43 CD40-CD154 interaction is pivotal for cell-mediated immunity.

44 n of tolerance and foreign Ags to initiate T cell-mediated immunity.

45 well-characterized model for studying CD8+ T cell-mediated immunity.

46 terleukin-17A, indicating that PNAG promoted cell-mediated immunity.

47 crine function and metabolism, but also on T cell-mediated immunity.

48 hat has been implicated as an inhibitor of T cell-mediated immunity.

49 cytosis rates, which leads to suppression of cell-mediated immunity.

50 g to the Ig superfamily and is essential for cell-mediated immunity.

51 ts capable of promoting balanced humoral and cell-mediated immunity.

52 ffectively induces antitumor and antiviral T cell-mediated immunity.

53 ency in the induction of protective CD8(+) T cell-mediated immunity.

54 ction and to evade the direct induction of T cell-mediated immunity.

55 is a co-inhibitory molecule that modulates T cell-mediated immunity.

56 development of vaccines designed to generate cell-mediated immunity.

57 strategies are needed for the elicitation of cell-mediated immunity.

58 d in the chemoattraction of monocytes and in cell-mediated immunity.

59 the effects of modeled microgravity (MMG) on cell-mediated immunity.

60 presumably acquiring the capacity to promote cell-mediated immunity.

61 igen-presenting cell function and defects in cell-mediated immunity.

62 emonstrated in those with strong humoral and cell-mediated immunity.

63 long been assumed to be solely dependent on cell-mediated immunity.

64 ngus Cryptococcus neoformans is dependent on cell-mediated immunity.

65 little as 150 PFU of ML29 induced protective cell-mediated immunity.

66 hysiology), donor-specific antibodies, and T cell-mediated immunity.

67 rus neutralizing antibodies, as well as weak cell-mediated immunity.

68 programming have emerged as modulators of T-cell-mediated immunity.

69 r suppression of humoral alloimmunity as for cell-mediated immunity.

70 key role in generation of HLA peptides for T cell-mediated immunity.

71 gylus brasiliensis is orchestrated by type 2 cell-mediated immunity.

72 ase-modifying treatments in MS that affect T-cell-mediated immunity.

73 eonate is attributed in part to defects in T cell-mediated immunity.

74 e-MHC (pMHC) on cells is a key parameter for cell-mediated immunity.

75 ntranasal route and induced both humoral and cell-mediated immunity.

76 r contributing to the observed loss in CD8 T cell-mediated immunity.

77 nt B cell responses, humoral antibodies, and cell-mediated immunity.

78 akes the link between TLS and a protective B cell-mediated immunity.

79 g protein tyrosine phosphatases to enhance T cell-mediated immunity.

80 ng cytokines such as TGF-beta1 that regulate cell-mediated immunity.

81 n and binding is crucial for understanding B cell-mediated immunity.

82 infection in the host against the control of cell-mediated immunity.

83 tion with cps1-1 elicits long-lasting CD8+ T cell- mediated immunity.

84 nvolved in modifying tumour interaction with cell-mediated immunity; 2p22.3; 7p21.1 AHR, the dioxin r

85 U treatment in optimally activating a CD4+ T cell-mediated immunity against actinic keratoses and, po

86 The results indicate that cell-mediated immunity against blood-stage malarial para

87 these have the purpose to promote adaptive T cell-mediated immunity against cancer.

88 ittle is known about the cross-reactivity of cell-mediated immunity against drifted strains in childr

89 s in suppressing autologous and allogeneic T cell-mediated immunity against hematologic malignancies.

90 ast cancer (BC) and whether both humoral and cell-mediated immunity against HERV-K can be found in BC

91 which pathways are required for memory CD8 T cell-mediated immunity against liver stage Plasmodium in

92 ytolytic pathways that underlie memory CD8 T cell-mediated immunity against liver stage Plasmodium in

93 ex (MHC) class I proteins initiates CD8(+) T cell-mediated immunity against pathogens and cancers.

94 s an extrinsic factor counteracting CD4(+) T-cell-mediated immunity against tumour in old age.

95 mmunity, to evaluate the relationships among cell-mediated immunity, AIDS, and polymorphisms in CCR5,

96 een HIV-1 and HIV-2 is that more efficient T cell-mediated immunity allows for immune-mediated contro

97 We studied the relationship between VZV cell-mediated immunity and age after varicella or VZV va

98 Effective B cell-mediated immunity and antibody responses often requ

99 nts or of micronutrients alone on indexes of cell-mediated immunity and antiinflammatory plasma prote

100 tudy, we examined the role of T cell CD98 in cell-mediated immunity and autoimmune disease pathogenes

101 turn-off stage, leading to suppression of T-cell-mediated immunity and autoimmunity.

102 dritic cells (DCs), enables antigen-specific cell-mediated immunity and extended antigen presentation

103 e first demonstration of a role for R-Ras in cell-mediated immunity and further expand on the complex

104 RP12 as an intrinsic negative regulator of T-cell-mediated immunity and identify altered NF-kappaB re

105 In this study, the cell-mediated immunity and immunoglobulin avidity were e

106 tworks is a significant barrier to effective cell-mediated immunity and immunotherapy.

107 Human CMV infection is controlled by T cell-mediated immunity and in immunosuppressed transplan

108 y results in dysfunction of both humoral and cell-mediated immunity and increases the susceptibility

109 oreign antigens to induce strong humoral and cell-mediated immunity and is ideal for a prime-and-boos

110 Cell-mediated immunity and neutralizing antibodies contr

111 a complex bidirectional interaction between cell-mediated immunity and platelets exists during exper

112 Cell-mediated immunity and production of type 1 cytokine

113 We conclude that both innate and CD4+ T-cell-mediated immunity and proinflammatory bacterial fac

114 mplicates NK cells as negative regulators of cell-mediated immunity and suggest that NK cells, like C

115 f pro-TGF-beta1 in vivo, but FURIN's role in cell-mediated immunity and Th polarization has remained

116 pressed FURIN is also a central regulator of cell-mediated immunity and Th1/2 cell balance.

117 ific T cells, contribute to the anatomy of T cell-mediated immunity and tolerance.

118 ll differentiation and the balance between T cell-mediated immunity and tolerance.

119 nimals with paucibacillary disease have high cell-mediated immunity and variable levels of antibody.

120 mmunity, TLR9(-/-) mice showed low levels of cell-mediated immunity and were slightly more resistant

121 Malnutrition dampened cell-mediated immunity and would interfere with diagnost

122 opment of antigen-specific T cell receptors (cell-mediated immunity) and immunoglobulins (humoral imm

123 SRBC-induced cytokines, reduction in humoral/cell-mediated immunity, and antibody titer was observed.

124 T(FH) cells) are responsible for effective B cell-mediated immunity, and Bcl-6 is a central factor fo

125 Dysfunctional cell-mediated immunity appears to be important in the pa

126 Since both humoral immunity and cell-mediated immunity are essential in providing the ho

127 T helper 1 cell responses involved in cell-mediated immunity are key immune parameters that de

128 This finding points to cell-mediated immunity as a relevant pathogenetic mechan

129 nosurveillance, and the induction of T and B cell-mediated immunity, as previously demonstrated using

130 llular and molecular understanding of type-2-cell-mediated immunity, as well as new areas such as the

131 ects of the innate vs. adaptive (humoral and cell-mediated) immunity associated with the bacterial vi

132 ent of Treg cells specialized to control Th1 cell-mediated immunity at local sites of inflammation.

133 ocated in areas likely to have a key role in cell-mediated immunity at mucosal surfaces, the ways in

134 demonstrated to induce enhanced mucosal and cell-mediated immunity better than inactivated vaccines

135 not associated with alterations in CD4(+) T cell-mediated immunity but was preceded by enhanced neut

136 IL-12 initiates T1 cell development and cell-mediated immunity, but it is unclear whether IL-12

137 medroxyprogesterone acetate (MPA) can impair cell-mediated immunity, but mechanisms responsible for t

138 candidate adjuvant capable of driving potent cell-mediated immunity, but the mechanism by which it ac

139 glucocorticoids, which can suppress CD8(+) T cell-mediated immunity, but the mechanisms are incomplet

140 CD4(+) T cells promote effective CD8(+) T cell-mediated immunity, but the timing and mechanistic d

141 While cell-mediated immunity by CD4+ Th1-type cells is protect

142 Boosting T cell-mediated immunity by live attenuated vaccine Mycoba

143 elationship between these factors in shaping cell-mediated immunity by using intravital imaging of CD

144 Thus, cell-mediated immunity can function normally despite con

145 It is important to determine whether cell-mediated immunity can trigger macrophage antimicrob

146 sal ganglia and can reactivate due to waning cell-mediated immunity, causing HZ.

147 was tested for VZV antibody and VZV-specific cell-mediated immunity (CMI) at baseline, 8 weeks after

148 ngal pathogen that requires the induction of cell-mediated immunity (CMI) for host survival.

149 Cell-mediated immunity (CMI) is critically important for

150 d mononuclear cells (PBMCs), suggesting that cell-mediated immunity (CMI) may play a role in viral cl

151 s the effect on UVR suppression of cutaneous cell-mediated immunity (CMI) reflected by nickel contact

152 ella-zoster virus (VZV)-specific humoral and cell-mediated immunity (CMI) to herpes zoster (HZ) and p

153 (VZV) vaccine (zoster vaccine), which boosts cell-mediated immunity (CMI) to VZV and decreases the in

154 Cell-mediated immunity (CMI) was measured shortly after

155 tage of CD4 T cells, spontaneous recovery of cell-mediated immunity (CMI) was not seen for TT.

156 (MeV) neutralizing antibody concentrations, cell-mediated immunity (CMI), and immunoglobulin G (IgG)

157 odeficiency virus 1 (HIV-1) relies mainly on cell-mediated immunity (CMI), the determinants of CMI in

158 pressed by antibody-mediated immunity and/or cell-mediated immunity (CMI).

159 together with IL28B.rs12979860 genotypes and cell-mediated immunity (CMI).

160 interleukin 2 (IL-2; markers of VZV-specific cell-mediated immunity [CMI], measured by means of ELISP

161 and transiently malnourished had compromised cell-mediated immunity comparable to that of the rabbits

162 of serotype-specific capsular polysaccharide cell-mediated immunity contributes to the clearance of G

163 T-cell-mediated immunity contributes to the pathogenesis o

164 s required in many instances for effective T cell-mediated immunity, controlling proliferation, and s

165 Although cell-mediated immunity controls intracellular infection,

166 NK cell-mediated immunity correlated with the ordered migra

167 Monitoring of CMV- and VZV-specific cell-mediated immunity could inform immunocompetence and

168 Further, local cell-mediated immunity could not be demonstrated by tetr

169 Cell-mediated immunity critically depends on the localiz

170 Effector-T-cell-mediated immunity depends on the efficient localiza

171 competent memory cells and sustains CD8(+) T-cell-mediated immunity during persistent virus infection

172 It is possible that diminished cell-mediated immunity during pregnancy could increase v

173 nd will help further define the decline in T cell-mediated immunity during the sepsis-induced phase o

174 induction of antimicrobial activity and/or T-cell-mediated immunity during Toxoplasma infection.

175 igen 4 (CTLA-4) is important in regulating T cell-mediated immunity, encompassing the first line of r

176 herefore play a nonredundant role in T and B cell-mediated immunity, especially for protection agains

177 us cell carcinoma (SCC VII/SF) we studied NK cell-mediated immunity following vaccination with a reco

178 The importance of T cell-mediated immunity for resistance to the disease (cr

179 On the contrary, cell-mediated immunity generated by primary influenza in

180 Suppression of cell-mediated immunity has been proposed as a mechanism

181 The role of T-cell-mediated immunity in AIDP remains unclear and there

182 genicity assessed with laboratory markers of cell-mediated immunity in blood and bronchoalveolar lava

183 ignificant SIV-specific mucosal and systemic cell-mediated immunity in both groups, whereas SIV-speci

184 guinea pigs and marmosets and virus-specific cell-mediated immunity in both simian immunodeficiency v

185 mportance for understanding the evolution of cell-mediated immunity in gnathosomes.

186 olar UV radiation (UVR) suppresses cutaneous cell-mediated immunity in humans.

187 recombinant vaccines for eliciting CD8(+) T cell-mediated immunity in humans; however, prior exposur

188 IV type 1 gag was shown to induce protective cell-mediated immunity in mice against viruses that expr

189 Ctsb(-/-) mice, consistent with a defect in cell-mediated immunity in mice lacking cathepsin L or S.

190 at IL PV-10 therapy induces tumor-specific T cell-mediated immunity in multiple histologic subtypes a

191 nflammatory diseases, the observed role of T-cell-mediated immunity in periodontitis did not readily

192 ed how Gads deficiency would impact CD8(+) T cell-mediated immunity in the context of infection with

193 Consequently, the protective role of cell-mediated immunity in the control of dengue infectio

194 mental model for further dissecting CD4(+) T-cell-mediated immunity in the lung.

195 ocyte hyperplasia, vascular hyperplasia, and cell-mediated immunity in the skin are closely interrela

196 a murine model of immunotherapy to optimize cell-mediated immunity in the skin.

197 1 could play an important role in augmenting cell-mediated immunity in these patients.

198 ignaling improves antilisterial defenses and cell-mediated immunity, in general.

199 DS virus infections are rarely controlled by cell-mediated immunity, in part due to viral immune evas

200 immunity to fungal pathogens requires intact cell-mediated immunity initiated by DCs, we asked whethe

201 Adaptive, cell-mediated immunity involves the presentation of anti

202 alphabetaT-cell mediated immunity is traditionally characterised by

203 in SCID mice supports the hypothesis that T cell-mediated immunity is critical for host defense agai

204 Varicella-zoster virus (VZV)-specific cell-mediated immunity is important for protection again

205 Cell-mediated immunity is required for the control of th

206 ay a major role in the improvement, and that cell-mediated immunity is the key to understanding E. co

207 Central to CD8(+) T cell-mediated immunity is the recognition of peptide-maj

208 A central paradigm in alphabeta T cell-mediated immunity is the simultaneous co-recognitio

209 Fitness of cell-mediated immunity is thought to depend on TCR diver

210 nses, which can accompany attempts to induce cell-mediated immunity, it is crucial to know which isot

211 Given that cell-mediated immunity may also contribute to parasite c

212 CMV-specific cell-mediated immunity may be able to predict which pati

213 cognized by T lymphocytes, suggesting that T-cell-mediated immunity may be harnessed for the immunoth

214 Exposed birds had significantly lower cell-mediated immunity (measured using phytohaemagglutin

215 IN-H and pMSINH-FdU elicited strong Th1 type cell-mediated immunity, measured by T cell proliferation

216 Due to functionally distinct cell-mediated immunity, newborns and infants are highly

217 tionally focused on producing humoral and/or cell-mediated immunity, often against the viral surface

218 eceptors, less is known about the effects of cell-mediated immunity on Beclin 1 and ULK1, key regulat

219 use of morbidity in patients with defects in cell-mediated immunity or saliva production.

220 e response and no effect on other markers of cell-mediated immunity or systemic and gut inflammation.

221 microMT mice as recipients, we found that T-cell-mediated immunity plays a secondary but still signi

222 Cell-mediated immunity plays an important role in immuni

223 disease occurs in the context of suppressed cell-mediated immunity post-transplantation, humoral imm

224 riggers immunomodulating events that enhance cell-mediated immunity, raising the possibility that lig

225 versus 2D (M0,12); neutralizing antibodies; cell-mediated immunity; reactogenicity; and safety.

226 n contrast to their role in limiting chronic cell-mediated immunity, regulatory T cells may play no s

227 cing lifelong protective B-cell responses, T-cell-mediated immunity remains challenging.

228 However, how DRD3 signaling affects T cell-mediated immunity remains unknown.

229 CMV-specific cell-mediated immunity represents a relevant marker in a

230 We now report that IL-12, a signature of cell-mediated immunity, represses Eomes while positively

231 Protective CD8(+) T cell-mediated immunity requires a massive expansion in c

232 T cell-mediated immunity requires T cell receptor (TCR) cr

233 act sensitivity (CS), a classic example of T cell-mediated immunity, requires Ag-specific IgM Abs to

234 virus (HCV) infection decreases humoral and cell-mediated immunity responses to hepatitis B vaccinat

235 mmunospot and antigen-specific proliferative cell-mediated immunity responses.

236 Purine analogues and alemtuzumab alter cell-mediated immunity, resulting in opportunistic viral

237 play an important role in the suppression of cell-mediated immunity seen in HIV infection.

238 e major new information involves the role of cell-mediated immunity, specifically T-helper 17 cells a

239 Cell-mediated immunity stems from the proliferation of n

240 Defects in cell-mediated immunity, such as thymic atrophy, impaired

241 CD4 T cells are crucial for enhancing B cell-mediated immunity, supporting the induction of high

242 that can coordinately induce multi-epitope T cell-mediated immunity, T helper functions, and immunolo

243 hat destruction of transduced hepatocytes by cell-mediated immunity targeting antigens of the AAV cap

244 s is an emerging approach to elicit CD8(+) T cell-mediated immunity targeting pathogens and tumor Ags

245 vs. periodontal microbial infections; (ii) T-cell-mediated immunity, Th-cytokines, and osteoclastogen

246 s with similar or even higher PRN titers and cell-mediated immunity than adult mice.

247 ccination strategy induced specific CD8(+) T cell-mediated immunity that eradicated spontaneous and e

248 sign because of the physiological changes in cell-mediated immunity that occur throughout life.

249 , pleiomorphic cells capable of modulating T cell-mediated immunity, that heretofore have been studie

250 Thus, during transition to adaptive T cell-mediated immunity, the ILC2 and T cell crosstalk co

251 Thus, cell-mediated immunity through CD40 stimulation can rero

252 ith WISP1 as a paracrine inhibitor of type 1 cell-mediated immunity through inhibiting IL12 signaling

253 (TNFR) superfamily, has a pivotal role in B-cell-mediated immunity through various effector pathways

254 ncludes a combination of innate, humoral and cell-mediated immunity) through mucosal vaccination migh

255 s, whereas MyD88(-/-) mice completely lacked cell-mediated immunity, TLR9(-/-) mice showed low levels

256 model to investigate the role of humoral and cell-mediated immunities to influenza and their effect o

257 The induction of cell-mediated immunity to C. albicans is of critical imp

258 The induction of cell-mediated immunity to C. albicans is one of the main

259 nd HSP70 play a key role in the induction of cell-mediated immunity to carcinogenic polyaromatic hydr

260 We tested the role of cell-mediated immunity to collagen type V [col(V)] in th

261 n of the immune system, allowing more potent cell-mediated immunity to develop in dangerous environme

262 T cell-mediated immunity to infection is due to the prolif

263 s to a T-dependent Ag, as well as impaired T cell-mediated immunity to infection with Listeria monocy

264 Thus, optimal NK cell-mediated immunity to MCMV depends on Ly49H signalin

265 T cell-mediated immunity to microbes and to cancer can be

266 onses has served as a paradigm to understand cell-mediated immunity to microbial pathogens.

267 estions remain regarding the significance of cell-mediated immunity to MSP1 in conferring protection

268 EAE is induced by stimulating T-cell-mediated immunity to myelin antigens.

269 eningitidis, there is an absence of adaptive cell-mediated immunity to N. lactamica during the peak a

270 was recently reported to be important in Th2 cell-mediated immunity to parasitic infection.

271 ese studies confirm the presence of adaptive cell-mediated immunity to preerythrocytic malaria antige

272 ytotoxic T cells and natural killer cells of cell-mediated immunity to provide tumor (B16-ova-Melanom

273 eserved the T-cell compartment and sustained cell-mediated immunity to SIV.

274 eloped with the goal of generating long-term cell-mediated immunity to the obligate intracellular par

275 ever, there is little information concerning cell-mediated immunity to this pathogen.

276 in association with a progressive decline in cell-mediated immunity to varicella-zoster virus (VZV).

277 function and is critical in vivo for optimal cell-mediated immunity to viral and alloantigens.

278 ity responses, a powerful in vivo measure of cell-mediated immunity, to evaluate the relationships am

279 e environment became further resistant to NK cell-mediated immunity upon cancer cell infiltration.

280 ated the potential function of galectin-3 in cell-mediated immunity using peripheral blood monocytes.

281 This cell-mediated immunity vaccine did not prevent HIV-1 inf

282 ep Study directly assessed the efficacy of a cell-mediated immunity vaccine to protect against HIV-1

283 lecularly concoct adjuvants to elicit potent cell-mediated immunity via activation of innate and adap

284 ears thereafter were tested for VZV-specific cell-mediated immunity (VZV-CMI) by gamma-interferon ELI

285 Varicella-zoster virus (VZV) T-cell-mediated immunity (VZV-CMI) in older persons preven

286 ine in varicella-zoster virus (VZV)-specific cell-mediated immunity (VZV-CMI).

287 With a decline in VZV-specific cell-mediated immunity, VZV reactivates from ganglia and

288 mechanisms by which C. gattii might subvert cell-mediated immunity, we found that C. gattii failed t

289 Cs) play a major role in the initiation of T-cell-mediated immunity, we studied the effects of TPT on

290 nd few studies have included measurements of cell-mediated immunity.We assessed the effects of diets

291 Robust systemic and mucosal antibody- and T cell-mediated immunities were induced against both prote

292 e-specific and cross-reactive antibodies and cell-mediated immunity were measured.

293 erent roles: T cells contribute to and drive cell-mediated immunity, whereas B cells secrete Abs.

294 role in mediating type 1 cytokine-dependent cell-mediated immunity, which could be beneficial for at

295 3 and K5 suppress both cytokine-mediated and cell-mediated immunity, which ensures efficient viral av

296 ased resistance of Mig-deficient tumors to T cell-mediated immunity, which promotes the accelerated g

297 irus after the normal decline in humoral and cell-mediated immunity with time.

298 hy systemic immunization routes induce local cell-mediated immunity within the intestine and indicate

299 lls to downregulate MHC class I, to escape T-cell-mediated immunity without inducing susceptibility t

300 ns shape the T-cell repertoire, as well as T-cell-mediated immunity; yet, the mechanisms that underli