ライフサイエンスコーパス: cell-penetrating peptide

1 f coupled together with Tat basic peptide, a cell-penetrating peptide.

2 riticale microspores with the help of a Tat2 cell-penetrating peptide.

3 cell culture was demonstrated by fusion to a cell-penetrating peptide.

4 nterfere with the delivery properties of the cell-penetrating peptide.

5 ide conjugates containing oligoarginine as a cell-penetrating peptide.

6 g antisense oligonucleotides conjugated to a cell-penetrating peptide.

7 ewed, followed by analyzing pros and cons of cell penetrating peptides.

8 ny formation relative to electroporation and cell-penetrating peptides.

9 or investigating the direct translocation of cell-penetrating peptides.

10 e-rich peptides are among the most effective cell-penetrating peptides.

11 lar uptake and intracellular distribution of cell-penetrating peptides.

12 localized to tumors by targeted activatable cell-penetrating peptides.

13 11)) and mPCI (Arg(1)-Ala(18)) functioned as cell-penetrating peptides.

14 structural features of cationic amphipathic cell-penetrating peptides.

15 , ion binding in solution, and activation of cell-penetrating peptides.

16 high-throughput screening of the efficacy of cell-penetrating peptides.

17 s of cargo inside mammalian cells similar to cell-penetrating peptides.

18 imeric nanoparticles coated with activatable cell penetrating peptides (ACPPs), labeled with Cy5, gad

19 We recently developed activatable cell-penetrating peptides (ACPPs) that target contrast a

20 lize tumors during surgery using activatable cell-penetrating peptides (ACPPs), in which the fluoresc

21 Unlike the cationic cell-penetrating peptides, alpha-helical antennapedia-li

22 The helix 5 peptide fused to a cell-penetrating peptide also activated endogenous lysos

23 eable protein toxin gelonin via the aid of a cell-penetrating peptide (also termed as protein transdu

24 he in vivo utility of technologies employing cell penetrating peptides and bioportides may be comprom

25 Selected peptide linkers were conjugated to cell penetrating peptides and d-peptide cargoes.

26 linear peptidyl ligands through fusion to a cell-penetrating peptide and cyclization of the fusion p

27 H2O2 through release of the highly adhesive cell-penetrating peptide and disruption of fluorescence

28 aining cleavable linker between polycationic cell-penetrating peptide and polyanionic fragments.

29 in labelled oligonucleotides with a range of cell-penetrating peptides and investigate their abilitie

30 Cell-penetrating peptides and proteins (CPPs) are import

31 HDMs has a predicted structural analogy with cell-penetrating peptides and that both the entire prote

32 t the DSS domain of DPP functions as a novel cell-penetrating peptide, and these findings demonstrate

33 protamine substitute as well as a non-toxic cell penetrating peptide applicable to achieve intracell

34 Cell-penetrating peptides are widely used to deliver car

35 lian nuclear localization sequences and many cell penetrating peptides as molecular sleds.

36 y is enhanced by the action of targeting and cell-penetrating peptides attached to the calcium silica

37 heptapeptide (MSP) fused to an arginine-rich cell-penetrating peptide (B-peptide) and conjugated to a

38 Our novel tumor cell-penetrating peptide-based probe (TPP) recognizes an

39 ompared to a PNA705 conjugate with a leading cell-penetrating peptide being developed for therapeutic

40 inib in the human CML cell line K562 using a cell-penetrating peptide biosensor and multiple reaction

41 ytic enzyme MMP-2, the probe, an activatable cell-penetrating peptide, Ceeee[Ahx]PLGLAGrrrrrK, labele

42 Hundreds of sequences now fall within the cell penetrating peptide classification and HIV-Tat, pen

43 Cell-penetrating peptides combined with a dominant negat

44 We designed cell-penetrating peptides comprised of the translocating

45 Recently, novel cell-penetrating peptide constructs such as HIV-1 TAT ba

46 nsitive nanocarriers, pre forming liposomes, cell penetrating peptide containing systems and virosome

47 Remarkably, a cell-penetrating peptide containing the N-terminal seque

48 Incubation of cultured SMCs with a cell-penetrating peptide containing the N-terminal seque

49 A cell-penetrating peptide containing this sequence compet

50 In this study, a cell penetrating peptide, containing the core HIV-1 Tat

51 ne linear bifunctional sequence containing a cell penetrating peptide (CPP) and a nuclear localizatio

52 We have investigated a range of cell penetrating peptide (CPP) conjugates of a 16mer pep

53 s into intact RBCs, which was meditated by a cell penetrating peptide (CPP) developed in our lab-low

54 Among these approaches, cell penetrating peptide (CPP) is promising and affords

55 g of antibodies linked with heparin, and the cell penetrating peptide (CPP) modified drug component.

56 Here, we report an activatable cell penetrating peptide (CPP) strategy ultimately aimed

57 es bearing one or two sequences containing a cell penetrating peptide (CPP), a nuclear localization s

58 ith low molecular weight protamine (LMWP), a cell penetrating peptide (CPP), insulin showed greatly i

59 Among those strategies, enzyme-triggered cell penetrating peptide (CPP)-mediated systems seem to

60 lf-peptide on DCs through linkage of it to a cell penetrating peptide (CPP).

61 Cell penetrating peptides (CPP) and cationic antibacteri

62 action and their ability to be conjugated to cell penetrating peptides (CPP) to overcome challenging

63 The hybrid peptide containing cell-penetrating peptide (CPP) and collagen (COLL) domai

64 In the current study, we have developed a cell-penetrating peptide (CPP) conjugate of the HIV TAT

65 hich the fluorescently labeled, polycationic cell-penetrating peptide (CPP) is coupled via a cleavabl

66 ical mediated oligomerization, IAPP acquires cell-penetrating peptide (CPP) properties, facilitating

67 in of HIV-1 TAT, TAT(48-60), is an efficient cell-penetrating peptide (CPP) that diffuses across the

68 ith low molecular weight protamine (LMWP), a cell-penetrating peptide (CPP) which was shown to effici

69 sidues in its structure, could function as a cell-penetrating peptide (CPP), also termed protein tran

70 ed using recombinant technology to contain a cell-penetrating peptide (CPP), i.e. Model Amphipathic P

71 Although it is a highly competitive cell-penetrating peptide (CPP), its relatively large siz

72 goarginine peptide R9C, a prototype cationic cell-penetrating peptide (CPP), with planar lipid membra

73 in, we report a simple yet effective system, cell-penetrating peptide (CPP)-assisted poly(lactic-co-g

74 A cell-penetrating peptide (CPP)-morpholino oligonucleotid

75 helical structure of CAI and convert it to a cell-penetrating peptide (CPP).

76 Peptide therapy using cell-penetrating peptides (CPP) as peptide carriers is p

77 ic behavior of molecular transporters of the cell-penetrating-peptide (CPP) type on a biological memb

78 Cell-based delivery of cell penetrating peptides (CPPs) could represent a new p

79 Cell penetrating peptides (CPPs) have attracted recent i

80 Cell penetrating peptides (CPPs) have been extensively s

81 NLCs was modified with six-histidine tagged cell penetrating peptides (CPPs) or YKA.

82 For cell penetrating peptides (CPPs) to fulfil their promise

83 weight:weight) ratio; and (iii) inclusion of cell penetrating peptides (CPPs).

84 the use of synthetically conjugated cationic cell penetrating peptides (CPPs).

85 some overlap in the biological activities of cell-penetrating peptides (CPPs) and antimicrobial pepti

86 emonstrated by polymerizing well-established cell-penetrating peptides (CPPs) and showing that the re

87 luence the delivery of cargoes into cells by cell-penetrating peptides (CPPs) and the bactericidal ac

88 Cationic cell-penetrating peptides (CPPs) are a promising vehicle

89 Although cationic cell-penetrating peptides (CPPs) are able to bind to cel

90 t siCPDs are nontoxic under conditions where cell-penetrating peptides (CPPs) are cytotoxic.

91 Cell-penetrating peptides (CPPs) are promising molecules

92 Arginine-rich cell-penetrating peptides (CPPs) are promising transport

93 Cell-penetrating peptides (CPPs) are short peptide seque

94 Cell-penetrating peptides (CPPs) are small cationic pept

95 Cell-penetrating peptides (CPPs) are well established as

96 Many cell-penetrating peptides (CPPs) fold at cell surfaces,

97 Hundreds of cationic antimicrobial and cell-penetrating peptides (CPPs) form amphipathic alpha-

98 of this peptide by incorporating a series of cell-penetrating peptides (CPPs) into the DGEA sequence.

99 Cellular association of polyarginine-based, cell-penetrating peptides (CPPs) is effectively blocked

100 coating of these blended particles with the cell-penetrating peptides (CPPs) mTAT, bPrPp and MPG via

101 Cell-penetrating peptides (CPPs) promote the uptake of d

102 Cell-penetrating peptides (CPPs) provide promising tools

103 In this study we have employed cell-penetrating peptides (CPPs) to deliver the ALS-asso

104 ein transduction domains (PTDs), also called cell-penetrating peptides (CPPs), can promote uptake of

105 airpin family of protegrin-1 (PG-1), and two cell-penetrating peptides (CPPs), HIV TAT and penetratin

106 Cell-penetrating peptides (CPPs), such as the HIV TAT pe

107 jugation of our reporter system to different cell-penetrating peptides (CPPs), we were able to achiev

108 3-1851) for short sequences that function as cell-penetrating peptides (CPPs).

109 al transcription factors (ATFs) are fused to cell-penetrating peptides (CPPs).

110 heroids to screen and identify BBB-penetrant cell-penetrating peptides (CPPs).

111 n two new concepts to activate arginine-rich cell-penetrating peptides (CPPs).

112 Conjugation of the cell-penetrating peptide derived from the human immunode

113 this cell line was resistant to uptake of a cell-penetrating peptide derived from the TAT protein.

114 Guanidinium-rich molecules, such as cell-penetrating peptides, efficiently enter living cell

115 Using an activatable cell-penetrating peptide engineered to detect thrombin a

116 Indeed, current methods (using cell-penetrating peptides for instance) provide very low

117 us TAT protein transduction domain (PTD), or cell-penetrating peptide, has previously been surmised t

118 Covalent attachment of a cell-penetrating peptide helps to improve cell delivery

119 We have developed an AAC-11-derived cell-penetrating peptide, herein named RT53, mimicking i

120 Cell penetrating peptides hold considerable potential fo

121 GFR-specific GE11 peptide), acid-activatable cell-penetrating peptides (i.e., TH peptide), and imagin

122 Our results showed that P12 acted like some cell-penetrating peptides in that it redirected ligand-b

123 -exchange studies in solution, activation of cell-penetrating peptides in vesicles, and computational

124 six different antimicrobial, cytolytic, and cell-penetrating peptides, including some of their varia

125 Antimicrobial, cytolytic, and cell-penetrating peptides induce pores or perturbations

126 Targeting MUC1-C with the cell-penetrating peptide inhibitor GO-203 disrupts MUC1-

127 M cells, and targeting MUC1-C with GO-203, a cell-penetrating peptide inhibitor of MUC1-C homodimeriz

128 ore and Rosbash discuss a new strategy using cell-penetrating peptide inhibitors for unraveling the r

129 Cell-penetrating peptide inhibitors of the MUC1-C subuni

130 ctivating transcriptional activator (TAT), a cell-penetrating peptide, is extensively used for facili

131 -activated protein kinase 2 (MK2)-inhibiting cell-penetrating peptide (KAFAK).

132 blems by mucoadhesive NPs (MNPs) loaded with cell penetrating peptide-linked insulin conjugates.

133 This proof-of-concept cell-penetrating peptide may aid validation of capsid as

134 Cell-penetrating peptide-mediated delivery of phosphorod

135 GFP protein either by electroporation or by cell-penetrating peptide-mediated import leads to format

136 dings relating to experimental protocols and cell penetrating peptide modifications or extensions tha

137 A cell-penetrating peptide-modified fusogenic liposomal me

138 ich can be internalized via conjugation with cell-penetrating peptide moieties; and Cas9 ribonucleopr

139 ed delivery, previous studies have relied on cell penetrating peptides, nanoparticles or specific bio

140 necessary for EN1 function and an N-terminal cell-penetrating peptide/nuclear localization sequence.

141 p28 is an anionic cell-penetrating peptide of 28 amino acids that activate

142 Here, we investigate the effect of cell-penetrating peptides on the biological activity of

143 The interaction between the cell-penetrating peptide, penetratin, and solid-supporte

144 The membrane-bound conformation of a cell-penetrating peptide, penetratin, is investigated us

145 Applying this method to a cell-penetrating peptide, penetratin, we found that at l

146 ion of scFvs, we investigated the utility of cell-penetrating peptides, penetratin and transactivator

147 eral tumor cells only when it was fused to a cell-penetrating peptide (pep5-cpp), suggesting its intr

148 Using a cell-penetrating peptide (pepducin) approach, we provide

149 Cell-penetrating peptide PepFect6 (PF6) has been shown t

150 These data may also explain variability in cell-penetrating peptide performance in different experi

151 This study demonstrates that the cell penetrating peptide-photosensitiser bioconjugation

152 iamidate morpholino oligomer with a designed cell-penetrating peptide (PPMO) targeting a mutated dyst

153 Fusion of cyclic peptides with a cyclic cell-penetrating peptide produces bicyclic peptides that

154 ral elements of ApoB-100 indicate it to have cell-penetrating peptide properties.

155 ed in real time with ratiometric activatable cell penetrating peptides (RACPPs).

156 We designed two new cell-penetrating peptides - RB1 and RB3 - that penetrate

157 Here we show that a cell-penetrating peptide, ReACp53, designed to inhibit p

158 tic proteins interaction and, if linked to a cell-penetrating peptide, reduces glutamate release in a

159 nctional filaggrin (FLG) monomer linked to a cell-penetrating peptide (RMR) and to test the ability o

160 study, we demonstrate that an arginine-rich cell-penetrating peptide, (RXRRBR)(2)XB, dramatically im

161 Htt(NT) derivatives with C-terminal cell-penetrating peptide segments also exhibit excellent

162 croparticles with a fluorophore as well as a cell-penetrating peptide sequence, which facilitated the

163 These attributes suggest that related, cell-penetrating peptides should effectively inhibit act

164 Tp10 is a 21-residue, amphipathic, cationic, cell-penetrating peptide similar to helical antimicrobia

165 nhibit miRNA function using vehicles such as cell penetrating peptides, spherical nucleic acids, defo

166 from that of the well-known, highly cationic cell penetrating peptides such as the tat peptide from H

167 behavior of the well-known, highly cationic cell-penetrating peptides, such as the HIV tat peptide,

168 ely delivered to tumors using an activatable cell-penetrating peptide targeting matrix metalloprotein

169 t nanoparticle surface modification with the cell penetrating peptide TAT facilitates brain-specific

170 njugates (NTD, d-NTD and q-NTD) in which the cell penetrating peptide Tat is covalently connected to

171 The cell-penetrating peptide Tat (GRKKRRQRRRPPQGYG) was also

172 ve HA2 fusion peptide from influenza and the cell-penetrating peptide TAT from HIV.

173 rface modification of nanoparticles with the cell-penetrating peptide TAT increases their biophysical

174 a tetramethylrhodamine-labeled dimer of the cell-penetrating peptide TAT, dfTAT, penetrates live cel

175 se 2 (MMP2)-sensitive peptide linker (pp), a cell penetrating peptide (TAT), and a model drug (doxoru

176 ) (PLGA) nanoparticles (NPs) conjugated to a cell-penetrating peptide, TAT, was used to increase intr

177 Here, we demonstrate the utility of novel cell-penetrating peptides, termed 'pepducins', that act

178 ating properties of a conserved human origin cell penetrating peptide that may be harnessed as a nove

179 We have developed a cell-penetrating peptide that disrupts homodimerization

180 combinant protein is fused with Z12, a novel cell-penetrating peptide that promotes efficient protein

181 Pep-1 is a cell-penetrating peptide that represents a powerful stra

182 ng fundamentally from the positively charged cell-penetrating peptides, the biocompatibility, stabili

183 oligohistidine affinity tags to function as cell-penetrating peptides, this metal-chelating cell sur

184 etics of the translocation of arginine-rich, cell-penetrating peptides through membranes are still un

185 Conjugating cell penetrating peptides to the compact ligand coated Q

186 the polymer-coated QDs have been coupled to cell-penetrating peptides to facilitate intracellular up

187 e efficiencies with which three families of "cell-penetrating peptides" traffic to the cytosol of mam

188 ed anti-gammaH2AX antibody conjugated to the cell-penetrating peptide transactivator of transcription

189 The mechanism of the interaction between the cell-penetrating peptide transportan 10 (tp10) and phosp

190 ic model that we previously proposed for the cell-penetrating peptide transportan 10 (tp10), but with

191 NAs transported into cortical neurons by the cell-penetrating peptide transportan 10.

192 osed for PCI by conjugating the chlorin to a cell penetrating peptide, using bioorthogonal ligation c

193 e antiviral activity, but when a Tat-derived cell-penetrating peptide was appended, the resulting mol

194 A hydrogen peroxide (H2O2)-activated cell-penetrating peptide was developed through incorpora

195 uction properties of two basic arginine-rich cell penetrating peptides, we demonstrate widespread sys

196 beta-arrestin signaling process with a novel cell-penetrating peptide, we were able to inhibit both t

197 membrane helices 5 and 6 of CB1R, fused to a cell-penetrating peptide, were able to disrupt receptor

198 membrane and, when conjugated to a cationic cell-penetrating peptide, were indiscriminately cytotoxi

199 rg9-TAMRA, a representative highly cationic, cell-penetrating peptide, which entered cells only when

200 rt a family of novel ratiometric activatable cell-penetrating peptides, which contain Cy5 as far red