ライフサイエンスコーパス: cell-permeable

1 oxy)acetic acid (PEG) moiety that makes them cell permeable.

2 (KLAKLAK)(2) peptide that on its own was not cell permeable.

3 udies, from which we infer that the cycle is cell permeable.

4 ino-gamma-turn, from which we infer they are cell-permeable.

5 TAT-RasGAP317-326, a cell-permeable 10-amino acid-long peptide derived from t

6 A synthetic soluble, cell-permeable, 23-amino acid peptide termed kinesin-der

7 Introduction of either mutant IDH or cell-permeable 2HG was associated with repression of the

8 These compounds are cell permeable, able to decrease inflammatory activation

9 tance of actin remodelling was studied using cell-permeable actin polymerizing (jasplakinolide, 2 mic

10 ecifically detect apoptosis in vivo, a novel cell-permeable activatable caspase substrate, TcapQ647,

11 ET as well as a cell-permeable activator of PKA induce Notch target gene

12 ivation are still missing due to the lack of cell-permeable activators.

13 ut not by DN-MyD88, findings confirmed using cell-permeable, adapter-specific BB loop blocking peptid

14 A cell-permeable alpha7 helix peptide competitively inhibi

15 In vitro, supplementation with cell-permeable alphaKG directly supports ES-cell self-re

16 gh glutamine has many intracellular fates, a cell permeable analog of a tricarboxylic acid cycle (TCA

17 Indeed, selective activation of Epac by the cell-permeable analog 8-(4-chlorophenylthio)-2'-O-methyl

18 Selective activation of PKA by the cell-permeable analog N(6)-benzoyladenosine-3',5'-cyclic

19 8Br-cAMP, a cell-permeable analog of cAMP, had no effect on inhibiti

20 Exposure of BAECs to C(2)-ceramide, a cell-permeable analog of ceramide, mimicked the effects

21 ory effect of LY294002 was not reversed by a cell-permeable analog of cGMP.

22 imulated by forskolin, isoproterenol, or the cell-permeable analog, 8-bromo-cAMP.

23 endent transcription, we developed synthetic cell-permeable analogs of beta-catenin's helix C, which

24 Furthermore, dimeric aryl diketoacids are cell permeable and enhance insulin signaling in hepatoma

25 The resulting cyclic peptides are cell permeable and have improved proteolytic stability.

26 o compounds, RB-2-cb and RB-11-ca, which are cell permeable and highly selective covalent modifiers f

27 BI-9564 (2) is a cell permeable and noncytotoxic BRD9 inhibitor provided

28 The modularly assembled compounds are cell permeable and nontoxic as determined by flow cytome

29 ts, but our understanding of what makes them cell permeable and orally bioavailable is limited.

30 pplied to imaging acidic tissues, delivering cell-permeable and impermeable molecules to the cytoplas

31 In this work, we report a cell-permeable and metabolically stable nonphosphorylate

32 r that becomes fluorescent upon binding of a cell-permeable and non-toxic fluorophore.

33 ists of four steps: (i) loading cells with a cell-permeable and photo-activatable fluorophore, NPE-HC

34 peptide produces bicyclic peptides that are cell-permeable and retain the ability to recognize speci

35 enzyme activity requires that substrates are cell-permeable and that the generated products are easil

36 and PVS are resistant to solvolysis and are cell-permeable and thus hold promise for in vivo applica

37 These molecules proved to be soluble, cell-permeable, and active in a disease relevant functio

38 s new probe is water-soluble, non-cytotoxic, cell-permeable, and useful for mitochondrial imaging.

39 this report, we describe the use of a novel, cell-permeable antagonist of the interaction between HOX

40 SS31 is a cell-permeable antioxidant peptide that reduces intracel

41 in RA, was then analyzed by knockdown using cell-permeable antisense oligonucleotides.

42 display a highly increased response to a new cell-permeable APC/C inhibitor, apcin, but not to the sp

43 Herein, we report the first cell-permeable ATP analogue, ATP-polyamine-biotin (APB).

44 s Plk4 can be specifically inhibited using a cell-permeable ATP analogue.

45 foundation for the development of additional cell-permeable ATP analogues for cell-signaling research

46 ere we report the first predictive model for cell permeable background-free probe development through

47 ABT-737, a small molecule cell-permeable Bcl-2 antagonist that acts by mimicking B

48 In this work we report the development of cell-permeable beta1i and beta5i selective inhibitors th

49 This strategy was applied to generate a cell-permeable bicyclic peptidyl inhibitor against the N

50 iopharmaceuticals and for the development of cell-permeable biomolecules.

51 Pretreatment of wild-type cells with the cell-permeable biotinylated general caspase inhibitor b-

52 By pretreating the cells with a cell-permeable, biotinylated pan-caspase inhibitor that

53 By pretreating the cells with a cell-permeable, biotinylated pan-caspase inhibitor, we i

54 nd a basis for the design and development of cell-permeable, bivalent Smac mimetics.

55 hesis, and characterization of a nonpeptide, cell-permeable, bivalent small-molecule (SM-164) which m

56 The cell-permeable Ca(2+) buffer BAPTA-AM, the IP(3) recepto

57 In the present study, pretreatment with a cell-permeable Ca2+-chelating compound (BAPTA-AM) signif

58 The cell-permeable calcium chelator 1,2-bis(2-aminophenoxy)e

59 We introduce a selective and cell-permeable calcium sensor for photoacoustics (CaSPA)

60 We show that addition of different cell permeable CaM antagonists to cultured cells or load

61 studied in isolated rat hepatocytes using a cell-permeable cAMP analog, CPT-cAMP.

62 specific agonist, butaprost, or 8-Br-cAMP, a cell-permeable cAMP analog, promoted parasite survival.

63 osphorylation are rescued by the addition of cell-permeable cAMP analogs, suggesting that cAMP metabo

64 with stumpy characteristics when exposed to cell-permeable cAMP and AMP analogues.

65 oying active caveolin-1 fragments coupled to cell-permeable carrier peptides may represent a novel ap

66 We have synthesized a highly cell-permeable caspase-3 substrate, DEVD-NucView488, by

67 sion of exogenous H2O2 scavengers, including cell permeable catalase and N-acetyl-L-cysteine, inhibit

68 storation of functional CAV1 domains using a cell-permeable CAV1 scaffolding domain peptide.

69 ther hand, increasing cellular ceramide with cell-permeable ceramide treatment resulted in attenuatio

70 Our results revealed that treatment with cell permeable cGMP derivatives, or the cGMP phosphodies

71 first reported low-nanomolar, selective and cell permeable chemical probe for ATAD2.

72 poxic angiogenesis during adipogenesis using cell-permeable chemical conjugates composed of antisense

73 copy with newly developed, freely diffusing, cell-permeable chemical probes with targeted affinity fo

74 ts rapid timescale of action and the lack of cell-permeable, chemical modulators.

75 ch was partially reversed by the addition of cell-permeable cholesterol.

76 Here, we show that a cell-permeable competing peptide (P6) functions as a spe

77 s a direct sensor for guest binding and as a cell-permeable compound for imaging applications.

78 ortunities for the rational design of future cell-permeable compounds and for the optimization of del

79 Cell-permeable compounds that bind effectively and selec

80 -binding peptides into more serum-stable and cell-permeable compounds.

81 A potent, cell-permeable, conformationally constrained second mito

82 Cell-permeable, constitutively active Stat6 is effective

83 Here we synthesized a cell permeable curcumin probe (Cur-P) with an alkyne moi

84 Treatment of BeWo cells with the cell permeable cyclic AMP analogue dibutyryl cyclic AMP

85 These cell-permeable cyclic peptides inhibit Ras signaling by

86 A cell-permeable decoy peptide corresponding to the same p

87 the utility of this chemistry in creating a cell-permeable derivative of a high-affinity HIV Rev pro

88 Preincubation with a cell-permeable derivative of C3 transferase that blocks

89 Calcein AM, the cell-permeable derivative of calcein, shows significant

90 nd subsequently culturing these cells with a cell-permeable, diazirine-modified form of GlcNAc-1-phos

91 1 (10),3,5,7-friedelatetraen-29-oic acid), a cell-permeable dienonephenolic triterpene compound, reve

92 ewly designed and structurally characterized cell permeable diformyl-p-cresol based receptor (HL) sel

93 -imidazole (Py-Im) polyamides are a class of cell-permeable DNA-binding small molecules that can disr

94 y manipulating actin dynamics are limited to cell-permeable drugs that preclude single-cell perturbat

95 Using SYTO62, a biocompatible and cell-permeable dye, we demonstrate photoconversion in a

96 Compound 3 is cell-permeable, effectively activates caspases in whole

97 Importantly, SKI-1 inhibition by the cell-permeable enzyme inhibitor decanoyl-RRLL-chlorometh

98 A cell-permeable ester of alpha-ketoglutarate reversed the

99 ased during hyperammonaemia, and providing a cell-permeable ester of alphaKG reversed the lower TCA c

100 Addition of HNE or the cell-permeable esters of glutathionyl-4-hydroxynonenal (

101 e-specific agonists were measured by using a cell-permeable fluorescent Ca(2+) indicator dye.

102 ments have historically been performed using cell-permeable fluorescent dyes, although the use of the

103 lar labeling using these techniques requires cell-permeable fluorescent ligands, however, limiting ut

104 4,5-diaminofluorescein diacetate, a cell-permeable fluorescent molecule, was used to detect

105 Cell-permeable fluorescent tracers are used in a competi

106 we report the synthesis and application of a cell permeable, fluorescent small molecule (SR101-F-araN

107 work, we designed and synthesized a new live-cell-permeable, fluorescent light-up probe for real-time

108 n this study, we have used a newly developed cell-permeable fluorogenic GzB substrate to measure this

109 These cell-permeable fluorophores are exceptionally bright, wi

110 reported a general method to improve small, cell-permeable fluorophores which resulted in the azetid

111 Moreover, treatment with a cell-permeable form of 2-HG sensitized wild-type IDH1 AM

112 ophagy response to ammonia is abrogated by a cell-permeable form of pyruvate resulting from the scave

113 hat systemic or transdermal application of a cell-permeable form of the cytoplasmic domain of CTLA-4

114 addition of several arginines resulted in a cell-permeable FRET substrate SM-P124 (Ac-GRRRK(Dabcyl)-

115 of fumarate hydratase-proficient cells with cell-permeable fumarate.

116 vator of transcription peptide (TAT)-GILZ, a cell-permeable GILZ fusion protein, shortened resolution

117 Here we developed cell-permeable GIV-CT peptides by fusing a TAT-peptide t

118 eased markedly during apoptosis induced by a cell permeable glyoxalase 1 inhibitor.

119 ity was largely prevented by incubation with cell-permeable GSH monoethylester but not malate.

120 rein we report the antisense activities of a cell-permeable, guanidine-based peptide nucleic acid (PN

121 anic carbon pool contains more of the highly cell-permeable H2CO3, necessitating a substantial expend

122 llular studies confirm that this molecule is cell permeable, has low cytotoxicity and localizes prima

123 The design scheme starts with a cell-permeable heterocyclic cation that binds to AT base

124 contrast, protein kinase A inhibition with a cell-permeable highly selective peptide blocker did not

125 beta-peptides are usually not cell-permeable, however, and this feature limits their u

126 relevance of phosphorylated BAD BH3 by using cell-permeable, hydrocarbon-stapled BAD BH3 helices that

127 e Notch transactivation complex by using the cell-permeable, hydrocarbon-stapled synthetic peptide st

128 uman primary CD4(+) T cells, exposure to the cell-permeable IKKbeta inhibitor PS-1145 or genetic abla

129 wild-type active caspase-3 for detection and cell permeable inhibition is a valuable proof-of-concept

130 microtubule dynamics, we identified Pyr1, a cell permeable inhibitor of LIM kinase, which is the enz

131 CatS inhibition by a cell-permeable inhibitor abrogated the release of the he

132 By establishing 5-nitroisatin as a cell-permeable inhibitor for Torsin processing, we provi

133 h was repressed by Rp-8-pCPT-cGMPS, a potent cell-permeable inhibitor of cGKs.

134 of the ubiquitin-activating enzyme (E1), no cell permeable inhibitors of E1 have been identified.

135 Importantly, through treatment with cell-permeable inhibitors (4,5,6,7-tetrabromo-1H-benzotr

136 enylation as judged in experiments employing cell-permeable inhibitors of protein farnesyl transferas

137 lead structure for the design of potent and cell-permeable inhibitors of the menin-MLL1 interaction.

138 ene expression, yet there are few selective, cell-permeable inhibitors or suitable tool compounds for

139 5 years ago, their selective perturbation by cell-permeable inhibitors remains a fundamental challeng

140 eptides as potent, metabolically stable, and cell-permeable inhibitors to target the beta-catenin and

141 evel and applied it to the identification of cell-permeable inhibitors.

142 isoform-specific small interfering RNAs and cell-permeable inhibitory peptides.

143 knock-in mouse lacking the PDZ motif, and a cell-permeable interfering peptide, we found that this m

144 thyl ester)phenylphosphine borane complex, a cell-permeable intracellular disulfide-reducing drug, sl

145 ER Ca2+ release in permeabilized cells, and cell-permeable IP3 ester-induced Ca2+ elevation in intac

146 n of some yggX gshA mutant phenotypes by the cell-permeable iron chelator deferoxamine allowed the co

147 neuronal injury could be ameliorated with a cell-permeable iron chelator.

148 ckage of IRS-2/PI3K complex formation with a cell permeable IRS-2-derived tyrosine phosphopeptide inh

149 this work, we have successfully developed a cell-permeable kinase probe (DA-2) capable of proteome-w

150 Sirtinol, a cell-permeable lactone ring derived from naphthol, is a

151 ity is rescued by binding to a high affinity cell-permeable ligand.

152 Understanding how to design cell permeable ligands for intracellular targets that ha

153 Thus, cell permeable ligands that bind repetitive RNAs have be

154 hingosine (C(6)-ceramide), an anti-mitogenic cell-permeable lipid metabolite, limited vascular smooth

155 -34 motor neuron-like cells indicated that a cell-permeable LK-ester, LKE, was nontoxic and protectiv

156 S-adenosyl-L-methionine (SAM) analogues from cell-permeable methionine analogues by engineered SAM sy

157 We have developed the first cell-permeable, mitochondrially targeted modulators of t

158 In contrast, the cell-permeable, mitochondrially targeted PKCdelta-dF(1)F

159 orted protection against hypoxic injury by a cell-permeable, mitochondrially-targeted deltaPKC-d subu

160 8) and corresponding 5,7-dione (7) as potent cell-permeable MLK1/3 family-selective leads with in vit

161 to stabilize these mutants and found that a cell-permeable molecule called Shield-1 is the most effe

162 pound for a more soluble equivalent led to a cell-permeable molecule that selectively and efficiently

163 ent of a photocleavable analog of AP20187, a cell-permeable molecule used to dimerize FK506-binding p

164 late the function of specific proteins using cell-permeable molecules can be a powerful method for in

165 , control of gene expression with synthetic, cell-permeable molecules is within reach.

166 can also be efficiently inhibited by small, cell-permeable molecules.

167 ation of tagged proteins and, when used with cell-permeable multiuse affinity probes (MAPs), offers i

168 A water-soluble, cell-permeable naphthalene-based tetrazole was identifie

169 attenuated by pretreatment with tat-VIVIT, a cell-permeable NFAT inhibitory peptide.

170 ction byproduct; and we synthesized a novel, cell permeable nitrone, 2-2-3,4-dihydro-2H-pyrrole 1-oxi

171 s show that the differential bioreduction of cell-permeable nitroxides in tumor and normal tissue is

172 ction rate was investigated by MRI using two cell-permeable nitroxides, 4-hydroxy-2,2,6,6,-tetramethy

173 d atherosclerosis development and identifies cell-permeable NLS peptide as a potential anti-atheroscl

174 To inhibit the protein function, cell-permeable, non-helical constrained proteomimetics t

175 framework for designing the next generation cell-permeable nucleic acid mimics for regulating gene e

176 transporter loss or supplementation with the cell-permeable nutrient, methyl pyruvate, reversed ceram

177 rmal fibroblasts (HDFs) with combinations of cell-permeable OCT4, SOX2, KLF4, CMYC and either NANOG o

178 Cell-permeable orthosteric ligands can assist folding of

179 are increased by increasing GSH adducts with cell-permeable oxidized GSH (GSSG-ethyl ester) or 2-acet

180 In addition, cell permeable pentapeptides designed from Ku70, termed

181 nistered blocking anti-PAR2 antibodies, or a cell permeable peptide inhibitor of PAR2 signalling, pep

182 Syk substrate preference motifs linked to a cell permeable peptide, resulting in a biosensor that is

183 biological function in prostate cancer using cell-permeable peptide (CPP) as a delivery system.

184 Strikingly, a cell-permeable peptide (CPP) containing the C-terminal s

185 tion of the protein/protein interaction by a cell-permeable peptide (CTTN-I peptide) attenuated actin

186 ely, preventing D1R/GluN1 association with a cell-permeable peptide (TAT-GluN1C1) left individual D1R

187 e RSK1/PKARIalpha interactions with a small, cell-permeable peptide activates RSK1 and recapitulates

188 A cell-permeable peptide aminofluorocoumarin substrate det

189 olin bioavailability employing penetratin, a cell-permeable peptide carrier for a bioactive caveolin-

190 A cell-permeable peptide conjugated to the Akt-binding dom

191 nsitive to amino acid deprivation, whereas a cell-permeable peptide containing the GDI motif inhibits

192 flammatory and atheroprotective effects of a cell-permeable peptide containing the NF-kappaB nuclear

193 enzymatic inhibitor of LSD1, or TAT-SNAG, a cell-permeable peptide corresponding to the SNAG domain

194 A cell-permeable peptide corresponding to this region disr

195 A myristylated cell-permeable peptide derived from residues 395-407 of

196 , treating BMECs with cavtratin, a synthetic cell-permeable peptide encoding the caveolin-1 scaffoldi

197 Cell-permeable peptide inhibitor and siRNA against caspa

198 A cell-permeable peptide inhibitor of GSK-3beta, and lithi

199 This information was used to develop a cell-permeable peptide inhibitor that selectively inhibi

200 Dapk1, that is blocked by a neuroprotective cell-permeable peptide mimetic of the region.

201 This study examined whether a cell-permeable peptide mimicking the kinase-inhibitory r

202 To do this, we utilized a cell-permeable peptide of the outer mitochondrial membra

203 filing and leads for developing enhanced and cell-permeable peptide or small-molecule inhibitors.

204 This strategy was applied to generate a cell-permeable peptide substrate for real-time detection

205 incubation of IKKbeta-deficient MEFs with a cell-permeable peptide that blocks the interaction of NE

206 We designed a cell-permeable peptide that competes for the unique PDZ

207 d to convert a cell-impermeable peptide to a cell-permeable peptide that displays activity in cell-ba

208 rent results showed that administration of a cell-permeable peptide that disrupts GluR2 trafficking (

209 Here, we utilized a polyarginine-rich, cell-permeable peptide that represents the portion of th

210 teraction between JNK and Sab, we utilized a cell-permeable peptide to demonstrate that ischemia/repe

211 Short-term administration of a Cav-based cell-permeable peptide to MCT rats prevents the developm

212 We have shown that a cell-permeable peptide, a hormone (melanocyte stimulatin

213 Here we identify a cell-permeable peptide, dNP2, which efficiently delivers

214 Activation of Akt1 with a cell-permeable peptide, TAT-TCL1, blocks the amino-Nogo

215 ng of PKA on cardiac function, we designed a cell-permeable peptide, which we termed trans-activator

216 storation of functional CAV1 domains using a cell-permeable peptide.

217 Both the cell-permeable peptides reduced L. major infection in BA

218 RACK1, depleting Src or RACK1 and utilizing cell-permeable peptides that perturb RACK1's interaction

219 Exposure of VSMCs to cell-permeable peptides, which contained polyproline seq

220 tetraspanin-targeted reagents by the use of cell-permeable peptides.

221 nd synthesis of a novel series of potent and cell permeable peptidomimetic inhibitors of the human be

222 Hsp90 targeting using a cell-permeable peptidomimetic agent resulted in marked a

223 n-regulation of CaMKII by KN-62, a selective cell-permeable pharmacological inhibitor or a dominant n

224 with subcellular spatial resolution using a cell-permeable, photoactivatable chemical inducer of dim

225 Moreover, we found that a cell-permeable PIER abrogated HSP90 function and caused

226 Finally, a second generation of cell permeable Pin1 inhibitors was designed by replacing

227 Importantly, cell-permeable Pin1-FOXM1-blocking peptides repressed th

228 by the higher-order polyamine spermine or by cell-permeable PIP2, but these interventions had no effe

229 A cell-permeable PKCzeta pseudosubstrate peptide inhibitor

230 Here we show that a cell-permeable PKMz inhibitor, injected in the rat hippo

231 We demonstrate that PFI-3 is a potent, cell-permeable probe capable of displacing ectopically e

232 ve led to the characterization of a powerful cell-permeable probe to selectively image static, long-l

233 A set of phosphatase-stable, cell-permeable prodrug analogues inhibited cytokine-stim

234 This is a cell-permeable prodrug form of alpha-ketoglutarate, an i

235 ut-2-enyl diphosphate (HMBPP) or a synthetic cell-permeable prodrug, bis (pivaloyloxymethyl) (E)-4-hy

236 ed target biological analytes through use of cell-permeable profluorogenic probes is dependent on the

237 PR39, a naturally occurring and cell-permeable proline- and arginine-rich peptide, block

238 by chronic administration of MG132, a potent cell permeable proteasome inhibitor.

239 d their performance by screening against 160 cell-permeable protein kinase inhibitors.

240 TcpB is a cell-permeable protein with multiple functions, and its

241 agents, recombinant proteins, and artificial cell-permeable proteins have been developed to manipulat

242 y of acquiring potent, yet highly selective, cell permeable PTP inhibitory agents.

243 We report the development of a cell permeable, quenched squarine probe (CytoCy5S), whic

244 this study, the inhibitory mechanisms of the cell-permeable recombinant protein Hph-1-ctCTLA-4 on T c

245 s system that utilizes a light-programmable, cell-permeable reporter deliverable simultaneously to ma

246 Here, we used a cell-permeable, reversible inhibitor of the telomerase e

247 Toward this end, we have developed cell-permeable RF proteins (CP-RFs) incorporating newly

248 vitro treatment with the low molecular mass cell-permeable S-nitrosothiol S-nitrosocysteine ethyl es

249 dies demonstrate that potent, selective, and cell permeable S6K1 inhibitors can be prepared and provi

250 ll, our results demonstrate that many novel, cell permeable scaffolds exist beyond those found in ext

251 potential for development of small molecule cell-permeable serine hydrolase inhibitors that block MC

252 of human and rat NK-LGL leukemia cells with cell-permeable, short-chain C-ceramide (C) in nanoliposo

253 ive inhibition of hypothalamic SIRT1 using a cell-permeable SIRT1 inhibitor or SIRT1-shRNA negated th

254 he derivation of novel, selective, druglike, cell permeable SMAC mimics with cellular activity.

255 e discovery of a number of highly potent and cell-permeable Smac mimetics and yielded important new i

256 sing lead compound for the design of potent, cell-permeable Smac mimetics for cancer treatment.

257 Cell permeable small molecules that can be programmed to

258 Here we report a cell-permeable small molecule (JQ1) that binds competiti

259 PTP, confer upon TCPTP the ability to bind a cell-permeable small molecule (the biarsenical fluoresce

260 Instability is reversed when a cell-permeable small molecule binds this domain.

261 study, we investigated a novel non-peptide, cell-permeable small molecule, named LY5, to target STAT

262 ngineered destabilizing protein domain and a cell-permeable small molecule.

263 Chemical inducers of dimerization (CIDs) are cell-permeable small molecules capable of dimerizing two

264 Cell-permeable small molecules that enhance the stabilit

265 Development of cell-permeable small molecules that target enzymes invol

266 een hampered by the absence of PTP-specific, cell-permeable small-molecule agents.

267 These findings demonstrate that a synthetic, cell-permeable small-molecule can be developed as a SP-b

268 he development of DI-591 as a high-affinity, cell-permeable small-molecule inhibitor of the DCN1-UBC1

269 There is currently no highly specific, cell-permeable, small molecule inhibitor for ZAP-70; the

270 -dimethylxanthenone-4-acetic acid (DMXAA), a cell-permeable, small molecule that has anti-tumor activ

271 Here we report the design of synthetic, cell-permeable, stabilized alpha-helical peptides that t

272 Moellering et al. recently reported that a cell-permeable "stapled" synthetic peptide of the Notch

273 -3 regulation of PBEF was determined using a cell-permeable STAT-3 inhibitor peptide.

274 Application of a cell-permeable STEP-derived peptide that is resistant to

275 Using a cell-permeable substrate for caspase-3, the presence of

276 directly supports ES-cell self-renewal while cell-permeable succinate promotes differentiation.

277 In contrast, cell permeable superoxide dismutase, which metabolizes s

278 Treatment of fibres with the cell-permeable superoxide scavenger 4,5-dihydroxy-1,3-be

279 sibility of systemic tumor treatment using a cell-permeable Survivin antagonist.

280 regulation of AKAP79/150 by microinjecting a cell-permeable synthetic AKAP (A-kinase anchor protein)

281 tem disease, using successive application of cell-permeable, synthetic CRISPR RNAs to activate and th

282 f specific proteins in mammalian cells using cell-permeable, synthetic molecules.

283 We have designed a cell-permeable T-sensitive fluorescence lifetime-based n

284 ery of ZFN proteins, which are intrinsically cell-permeable; TALEN proteins, which can be internalize

285 plication of Smad7 protein conjugated with a cell-permeable Tat tag to oral mucosa showed prophylacti

286 We generated cell-permeable TAT-dominant-negative (dn)NFATc1 fusion p

287 involved the treatment of E. coli cells with cell-permeable tetrazoles followed by a brief photo irra

288 Because c-di-GMP is not cell permeable, the c-di-GMP hydrophobic analog 2'-O-di(

289 Also, the cell-permeable thiol N-acetyl l-cysteine, reverses DMF i

290 ulfide bond formation, we have synthesized a cell-permeable thiol-reactive affinity probe (TRAP) cons

291 ereby the intrinsic pore dilates, making the cell permeable to large organic cations, which eventuall

292 r studies show that the designed ligands are cell permeable to mouse myoblasts.

293 y cationic beta(3)-peptides are sufficiently cell permeable to upregulate p53-dependent genes in live

294 lso showed that alstotides are antiviral and cell-permeable to inhibit the early phase of infectious

295 ression, or preincubation of HMVEC-Ls with a cell-permeable TRAF6 decoy peptide decreased both LPS-in

296 y as a monosaccharide sensor, functions as a cell-permeable, turn-on fluorescent sensor for tetraseri

297 In the future, cell-permeable variants of XY-69 represent promising can

298 onfocal microscopy confirmed that the 2AI is cell permeable, while pull-down assays identified BfmR,

299 To enhance NPC migration, we generated a cell-permeable wild-type p38 protein (PTD-p38WT) in whic

300 desirable labelling probes should be highly cell permeable without nonspecific interactions with oth