ライフサイエンスコーパス: cell-to-cell

1 DNA replication origins, which differs from cell to cell.

2 ed domains and loops vary substantially from cell to cell.

3 eted by cells that transmit information from cell to cell.

4 ies might recruit normal tau by passage from cell to cell.

5 gen escapes results in bacterial spread from cell to cell.

6 ute for possible propagation of signals from cell to cell.

7 11, also known as OB cadherin or CDH11) is a cell-to-cell adhesion molecule implicated in many biolog

8 In addition, it regulates cell-to-cell adhesion, AMPK signaling, autophagy and apo

9 biomechanics of cell walls and in mediating cell-to-cell adhesion.

10 smosomes, multiprotein complexes involved in cell-to-cell adhesion.

11 CMV also spreads cell to cell and can induce syncytia.

12 vealed that misfolded tau can propagate from cell to cell and from region to region in the brain thro

13 all RNAs (sRNAs) that can move within plants cell to cell and long distance.

14 ins such as claudin-7 and occludin and other cell-to-cell and cell-to-matrix adhesion molecules in hu

15 of epithelial markers and genes involved in cell-to-cell and cell-to-matrix adhesion was reduced in

16 local balance of competing physical forces; cell-to-cell and cell-to-substrate forces.

17 We conclude that cell-to-cell and consequent lineage-to-lineage variabili

18 Random cell-to-cell and inter-monolayer variation in both ionic

19 HIV is transmitted most efficiently from cell to cell, and productive infection occurs mainly in

20 that facilitate efficient viral spread from cell to cell as a potential mechanism to escape host ant

21 steps of cell infection, genome packing, and cell-to-cell as well as host-to-host transfer.

22 o determine the efficiency of infection on a cell-to-cell basis.

23 ates the technical parameters, which reflect cell-to-cell batch effects, into a hierarchical mixture

24 cells in vivo and their biological effect in cell to cell communication during the adaptive immune re

25 uenching (QQ) is the disruption of bacterial cell-to-cell communication (known as quorum sensing), wh

26 Additionally, exosomes may mediate specific cell-to-cell communication and activate signaling pathwa

27 e involved in synaptic processes that govern cell-to-cell communication and could both contribute in

28 llular vesicles (EVs) play a pivotal role in cell-to-cell communication and have been shown to take p

29 and osteoclast activities both directly via cell-to-cell communication and indirectly via secreted f

30 ssociated GJs are required for the efficient cell-to-cell communication and viral spread.

31 While chemical forms of cell-to-cell communication are well recognized to coordi

32 g of a nutrient sensing network to allow for cell-to-cell communication between mitochondria in respo

33 d alphavbeta3 integrin mediate bidirectional cell-to-cell communication between neurons and astrocyte

34 ch as miRNAs, likely play important roles in cell-to-cell communication both locally and systemically

35 Here we reveal that SRC functions in cell-to-cell communication by controlling the biogenesis

36 n of bacterial motility and population based cell-to-cell communication demonstrates the versatility

37 are well characterized channels that mediate cell-to-cell communication during neurotransmission in a

38 served throughout plant evolution to mediate cell-to-cell communication during sexual reproduction.

39 gnaling molecule, plays an important role in cell-to-cell communication during tissue development.

40 ering plants, fertilization requires complex cell-to-cell communication events between the pollen tub

41 en recently reported as crucial mediators in cell-to-cell communication in development and disease.

42 osomes, have emerged as important players in cell-to-cell communication in normal physiology and path

43 otic bodies) are emerging as a novel mean of cell-to-cell communication in physiology and pathology b

44 Fast cell-to-cell communication in the brain is achieved by a

45 arbon receptor, the data suggest a disturbed cell-to-cell communication in this disease.

46 Cell-to-cell communication is essen for the development

47 fore potentially allow the identification of cell-to-cell communication mechanisms and biomarkers.

48 the potential for a unique vesicle-mediated cell-to-cell communication network within the ovarian fo

49 ce its discovery 22 years ago, the bacterial cell-to-cell communication system, termed quorum sensing

50 ormation from both environmental signals and cell-to-cell communication to influence PqsR levels.

51 the microbiota and chemical signaling during cell-to-cell communication to regulate several cellular

52 and abiotic stress through well-coordinated cell-to-cell communication to survive as sedentary organ

53 ave shown that exosomes play a vital role in cell-to-cell communication, and pathogenesis of many age

54 found that a large fraction of them involve cell-to-cell communication, extracellular matrix and tra

55 to measure >600 plasma proteins involved in cell-to-cell communication, was used to measure plasma p

56 and division; while migration, adhesion and cell-to-cell communication, were downregulated.

57 lants coordinate physiological responses via cell-to-cell communication.

58 re now recognized to play a critical role in cell-to-cell communication.

59 nd organism-wide impacts of ex-sRNA-mediated cell-to-cell communication.

60 conduction, and the spatial organization of cell-to-cell conductance variation was found to not impa

61 lls within a larger culture, allowing native cell-to-cell contact and communication even during vigor

62 transfection with miR-142-3p mimic inhibited cell-to-cell contact and fusion, decreased protein kinas

63 function through IL-10 production as well as cell-to-cell contact involving CTLA-4.

64 Furthermore, cell-to-cell contact is an important component of succes

65 tors, growth factor receptors, adhesion, and cell-to-cell contact molecules.

66 This rapid spread is based on cell-to-cell contact rather than on particle release and

67 une cells to epithelial cells also occurs by cell-to-cell contact rather than through cell-free parti

68 ound IgE, substantiated by a requirement for cell-to-cell contact, aggregation, and FcepsilonRI-depen

69 ner, and PGE2 secretion is down-regulated by cell-to-cell contact, attenuating its immunomodulatory p

70 uring HIV infection resulted in aberrant TNT cell-to-cell contact, compromising HIV spread and replic

71 NK cells in social microwells, which allow cell-to-cell contact, exhibited significantly higher lev

72 sue, and the regulation of its production by cell-to-cell contact, followed by the determination of i

73 by which bacteria exchange toxins via direct cell-to-cell contact.

74 enin, a membrane-binding adaptor involved in cell-to-cell contact/communication, to capture the Bro1

75 Thus, both infected MDMs and DCs rely on cell-to-cell contacts and nectin-4 to efficiently delive

76 bulogenesis requires the formation of stable cell-to-cell contacts and the establishment of apicobasa

77 smata are shaped irregularly with punctuated cell-to-cell contacts, metabolically responsive to envir

78 narrow intercellular separation can modulate cell-to-cell coupling via extracellular electric fields

79 p junction formation and thereby impairs the cell-to-cell coupling, which is independent of Wnt/beta-

80 For example, the complex pattern of cell-to-cell current flow that is responsible for AP con

81 ly, this variability does not correlate with cell-to-cell differences in cartilage-like matrix produc

82 ike occurs heterogeneously and propagates to cell-to-cell differences in mature mRNA expression.

83 ffected by heterogeneous protein expression, cell-to-cell differences in phagosome formation, and num

84 tor cells, our analysis reveals considerable cell-to-cell differences in their probability to transit

85 /Ca(2+) exchanger current determine RA human cell-to-cell differences through intracellular and sarco

86 cal units in tissues by allowing the lateral cell-to-cell diffusion of ions, metabolites and second m

87 tion, one of the viral egress mechanisms for cell-to-cell dissemination, and revealed an absence of a

88 variability in cellular components generates cell-to-cell diversity in RNA and protein production dyn

89 we report the highly efficient detection of cell-to-cell DNA methylation variability in liver tissue

90 ows the concise, comprehensive assessment of cell-to-cell DNA methylation variability.

91 In silico inferences of cell-to-cell excitatory and inhibitory connectivity and

92 Paused genes also have lower cell-to-cell expression variability.

93 Cell-to-cell expression variation (CEV) is a prevalent f

94 and HAP1-DeltaDAG1 cells, despite efficient cell-to-cell fusion activity.

95 rface expression, and the ability to mediate cell-to-cell fusion after low-pH exposure.

96 iruses released from PI cells induced higher cell-to-cell fusion than the parental virus following in

97 ated the role of SIV layer 3 in viral entry, cell-to-cell fusion, and CD4 binding.

98 F protein cleavage efficiency, facilitating cell-to-cell fusion, while HN169R possesses a multifacet

99 ding and wild-type levels of infectivity and cell-to-cell fusion.

100 c defects and not, as previously thought, by cell-to-cell fusion.

101 c loss in infectivity and ability to mediate cell-to-cell fusion.

102 Cell-to-cell HER2 heterogeneity was extensive in a propo

103 ell geometry and adhesive spacing are fixed, cell-to-cell heterogeneities in SF dissipated elastic en

104 ) techniques can reveal valuable insights of cell-to-cell heterogeneities.

105 Finally, these data demonstrate marked cell-to-cell heterogeneity amongst both chondrocytes and

106 ch, we highlight genes undergoing changes in cell-to-cell heterogeneity but whose overall expression

107 This study identifies the first case of cell-to-cell heterogeneity controlled by Rac1/RhoA antag

108 Its involvement in the regulation of cell-to-cell heterogeneity during epidermal morphogenesi

109 m between the GTPases Rac1 and RhoA controls cell-to-cell heterogeneity in isogenic populations of ce

110 nd cell-cycle state differences and identify cell-to-cell heterogeneity in mammalian chromosomal conf

111 structure and provides a route to assessing cell-to-cell heterogeneity in response to external stimu

112 Cell-to-cell heterogeneity is a major driver of cancer e

113 Microbial cell-to-cell heterogeneity is proposed as a mechanism of

114 scMAB-seq captures the cell-to-cell heterogeneity of 5fC and 5caC and reveals t

115 e subcellular spatial information or discern cell-to-cell heterogeneity within the bacterial populati

116 d single-cell methylome sequencing to assess cell-to-cell heterogeneity.

117 of widespread MAE might be the generation of cell-to-cell heterogeneity; the increased genetic variat

118 ates cell aggregation, which is required for cell-to-cell HIV transmission.

119 pha-synuclein (alpha-SYN) can propagate from cell to cell in a prion-like manner.

120 ers released from neurons can propagate from cell-to-cell in a prion-like fashion exacerbating neurod

121 latory communities differ substantially from cell to cell, indicating that expression variability cou

122 r ability to neutralize HIV-1 T/F viruses in cell-to-cell infection assays.

123 ivities to a panel of bNAbs in cell-free and cell-to-cell infection assays.

124 lizing antibody classes are decreased during cell-to-cell infection in a context-dependent manner.

125 zation capacity or in vitro efficacy against cell-to-cell infection of HIV-1 with T/F Envs compared t

126 ions, which act as reservoirs for subsequent cell-to-cell infection when host populations are expande

127 from high concentrations of antibody through cell-to-cell infection while remaining sensitive to neut

128 mplete neutralization of these T/F clones in cell-to-cell infection.

129 rs cell proliferation, death, migration, and cell-to-cell interaction through contact inhibition.

130 e that arises from the head-tail symmetry of cell-to-cell interaction).

131 that ECs can directly activate basophils via cell-to-cell interaction.

132 hat their morphology is sculpted by specific cell to cell interactions with neurons and each other.

133 des present on adjacent cells, thus creating cell to cell interactions.

134 nd the tumor microenvironment is mediated by cell-to-cell interactions and soluble factors.

135 hich fail to recapitulate spatial aspects of cell-to-cell interactions as well as tissue gradients pr

136 d of the macroscopic patterns resulting from cell-to-cell interactions remains largely qualitative.

137 evidence that migratory DCs execute targeted cell-to-cell interactions with stationary MCs before lea

138 se to the theoretically calculated limit and cell-to-cell interactions.

139 tumor microenvironmental patterns, including cell-to-cell interactions.

140 It is a cell-to-cell junction cardiomyopathy, typically caused b

141 F attenuates the linkage of stress fibers to cell-to-cell junctions with concomitant decrease in inte

142 At the level of cell-to-cell junctions, HGF attenuates the linkage of st

143 ult from malformed vascular walls with leaky cell-to-cell junctions.

144 en target cells, allowing the toxins to move cell-to-cell like an infectious agent.

145 lease progeny virions in a membrane-mediated cell-to-cell manner.

146 HIV-1 infection from cell-to-cell may provide an efficient mode of viral spre

147 e entry mechanism, we developed a virus-free cell-to-cell membrane fusion assay to identify the minim

148 ral SCs appears linked to its acquisition of cell-to-cell mobility in Brachypodium Physiological anal

149 f Cu-microRNA functions that account for the cell-to-cell mobility should give novel insight into pla

150 , and MAP kinase signalling is important for cell-to-cell movement of invasive hyphae in M. oryzae.

151 expression, or enhanced virion stability and cell-to-cell movement.

152 ta size-exclusion limits and promoting virus cell-to-cell movement.

153 This issue is important as cell-to-cell phenotypic heterogeneity may initiate key s

154 synchronized Lsr QS activation, arising from cell-to-cell population heterogeneity, could lead to bim

155 STM is a mobile protein that traffics cell-to-cell, presumably through plasmodesmata.

156 l-autonomous factors such as alpha-synuclein cell-to-cell propagation and neuroinflammation.

157 sis of alpha-syn thus potentially increasing cell-to-cell propagation of synuclein.

158 se role of this channel and the mechanism of cell-to-cell propagation of the wave have remained large

159 The quantitative study and visualization of cell-to-cell propagation using tagged-proteins is challe

160 As a result, S motility requires close cell-to-cell proximity and isolated cells do not translo

161 ate the contribution of alphaSMA-tdTomato(+) cells to cells secreting reparative dentin.

162 in vivo behaviors over multispatial (single cell to cell sheets) and temporal (minutes to weeks) sca

163 tablished that bacterial populations utilize cell-to-cell signaling (quorum-sensing, QS) to control t

164 ealed two significant overlapping pathways, "cell-to-cell signaling and interaction" and "neurologica

165 EBV hijacks the exosomal pathway to modulate cell-to-cell signaling by secreting viral components suc

166 interplay between epigenetics, genetics, and cell-to-cell signaling in cancer, with particular emphas

167 Cell-to-cell signaling is key to many of these interacti

168 The Notch pathway is a cell-to-cell signaling mechanism that is essential for t

169 s a necessary component in the P. aeruginosa cell-to-cell signaling network.

170 and gatekeepers for the propagation of rapid cell-to-cell signaling remains a key open question.

171 providing an opportunity for bi-directional cell-to-cell signaling to control the emergence of the h

172 ll density and uses the secreted peptide for cell-to-cell signaling to induce population-wide speB ex

173 fication of gap junctions on an asymmetry of cell-to-cell signaling.

174 nities can coordinate their behavior through cell-to-cell signaling.

175 trol haematopoiesis through a combination of cell-to-cell signalling and cytokine secretion that elic

176 tochondria may represent a potential mode of cell-to-cell signalling in the central nervous system.

177 rve as nutrient sources, osmoprotectants and cell-to-cell signalling molecules.

178 ell genome, facilitating an understanding of cell-to-cell similarities and distinctions.

179 ore, both viruses were severely defective in cell-to-cell spread and produced fewer DNA-containing ca

180 indings suggest that the mechanism(s) of HCV cell-to-cell spread differs from that of cell-free infec

181 these studies show that UL21 is required for cell-to-cell spread even in the absence of syncytial mut

182 replication and spread in MDDCs alone and in cell-to-cell spread in MDDC-CD4(+) T cell cocultures.

183 la spp. and facilitating cellular egress and cell-to-cell spread in the case of Brucella spp.

184 GBPs inhibit actin-dependent motility and cell-to-cell spread of bacteria but are antagonized by I

185 The findings reported here (i) confirm that cell-to-cell spread of CMV is sensitive to antibody inhi

186 ynthesis and release of infectious HSV-1 and cell-to-cell spread of infection were all impaired in ch

187 Cholesterol was also critical for cell-to-cell spread of infection.

188 Yields of progeny virus and cell-to-cell spread of the DeltaM25 mutant in vitro were

189 articles most likely are responsible for the cell-to-cell spread of the virus.

190 Efficient cell-to-cell spread of vaccinia virus and other orthopox

191 A36-driven super-repulsion in promoting the cell-to-cell spread of vaccinia.

192 ostattachment receptors in HCV infection and cell-to-cell spread remains controversial.

193 eminate through host tissues by a process of cell-to-cell spread that involves protrusion formation,

194 oprotein E was found to be important for HCV cell-to-cell spread, but very-low-density lipoprotein (V

195 ein E (apoE) is critically important for HCV cell-to-cell spread, unlike VLDL-containing mouse serum,

196 and SR-BI were found to modestly promote HCV cell-to-cell spread.

197 lation to resume actin-mediated motility and cell-to-cell spread.

198 aining mouse serum, which did not affect HCV cell-to-cell spread.

199 Cell-to-cell spreading of misfolded alpha-synuclein (alp

200 ed that simultaneous paracrine signaling and cell-to-cell surface contact regulate hepatocyte differe

201 ids, but organoid self-organization requires cell-to-cell surface contact.

202 To account for cell-to-cell technical differences, we propose a statist

203 Regardless of how signals move from cell to cell, they help prepare distant parts of the pla

204 These discoveries suggest that increased cell-to-cell transcriptional variability will be a hallm

205 We define the morphology of some HIV cell-to-cell transfer intermediates as true endocytic co

206 ell surface receptors may be involved in the cell-to-cell transfer, but proteoglycans are of interest

207 ighlight the role of astrocytes in alpha-SYN cell-to-cell transfer, identifying possible pathophysiol

208 ent phosphoramidate histidine-DNA adduct for cell-to-cell transfer.

209 e and can adapt to the environment, yielding cell-to-cell transmissibility, prion infectivity and tox

210 olved different strategies, including direct cell-to-cell transmission and cell-free transmission, to

211 studies showed that tau fibrils can undergo cell-to-cell transmission and seed aggregation of solubl

212 cell surface receptors in HCV cell-free and cell-to-cell transmission are poorly understood.

213 s (ALS), self-propagation of aggregation and cell-to-cell transmission have been demonstrated in vitr

214 HTLV-1 cell-to-cell transmission is dependent on the release of

215 The ability to fully inhibit cell-to-cell transmission may represent an important con

216 ed a novel model to test the hypothesis that cell-to-cell transmission of different tau strains occur

217 eading, it has little to no effect on direct cell-to-cell transmission of either vesicular stomatitis

218 is of Parkinson's disease (PD) may be due to cell-to-cell transmission of misfolded preformed fibrils

219 Direct cell-to-cell transmission of proteopathic alpha-synuclei

220 hed a cell culture model to characterize the cell-to-cell transmission of TAR DNA-binding protein and

221 l when a productively infected cell attempts cell-to-cell transmission of virus.

222 cells, we demonstrated the neurotoxicity and cell-to-cell transmission property of (GA)15 DPR.

223 of different receptors in HCV cell-free and cell-to-cell transmission remain elusive.

224 poietic tissues and cell monolayers involves cell-to-cell transmission that is resistant to tetherin

225 We observed resistance of cell-to-cell transmission to antibody neutralization tha

226 s of cell-free virion circulation and direct cell-to-cell transmission to retroviral dissemination an

227 TLV-1 spread, particularly in the context of cell-to-cell transmission, a critical step in HTLV-1 tra

228 L)-containing mouse serum did not affect HCV cell-to-cell transmission, although it inhibited cell-fr

229 on-randomness, both in the context of direct cell-to-cell transmission, and in the context of free vi

230 f US28-deficient HCMV, via culture medium or cell-to-cell transmission, was significantly impeded as

231 s are thought to spread primarily via direct cell-to-cell transmission, yet many have evolved to coun

232 LDLR greatly impaired both HCV cell-free and cell-to-cell transmission.

233 SDC-2, and TIM-1 also modestly decreased HCV cell-to-cell transmission.

234 tachment and postattachment receptors in HCV cell-to-cell transmission.

235 of individual receptors in HCV cell-free and cell-to-cell transmission.

236 exhibit a diminished ability to block HIV-1 cell-to-cell transmission.

237 N, and LDLR play more important roles in HCV cell-to-cell transmission.

238 ors are important for both HCV cell-free and cell-to-cell transmission.IMPORTANCE The importance and

239 table movement complexes that facilitate the cell-to-cell transport of SHR.

240 Cell-to-cell variability (noise) is an important feature

241 neficial mutations through synergism between cell-to-cell variability and genetic variation.

242 Due to large cell-to-cell variability and the lack of direct measurem

243 ions lead to transcriptional alterations and cell-to-cell variability can help unraveling genotype-ph

244 New tools that facilitate the study of cell-to-cell variability could help uncover novel cellul

245 enous EGFR in a cell line and shows a strong cell-to-cell variability even within the same cell line.

246 ging as a promising technology for profiling cell-to-cell variability in cell populations.

247 Cell-to-cell variability in cellular components generate

248 Understanding cell-to-cell variability in cytosine methylation is esse

249 wer ON/OFF switching, resulting in increased cell-to-cell variability in mRNA levels.

250 r any type of cellular control, showing that cell-to-cell variability in mtDNA and mutant load inevit

251 ew avenue in studying the functional role of cell-to-cell variability in physiological processes.

252 strate that heterozygous sequences can lower cell-to-cell variability in proportion to selection stre

253 nd frequency dependence may be determined by cell-to-cell variability in protein expression, which is

254 However, lin-22 mutants exhibit cell-to-cell variability in Wnt pathway activation, whic

255 Functional and molecular cell-to-cell variability is pivotal at the cellular, tis

256 We quantify cell-to-cell variability of adaptation, ligand response,

257 o the challenging problem of quantifying the cell-to-cell variability of plasmid copy number in bacte

258 es is inherently stochastic and manifests as cell-to-cell variability or noise in protein copy number

259 sses may change transcript levels and affect cell-to-cell variability or noise.

260 ns of cytokines were a source of non-genetic cell-to-cell variability that is often overlooked in sin

261 rter-mediated mechanisms fail to account for cell-to-cell variability within a population or adequate

262 Its cell-to-cell variability, a key player associated with c

263 unravel the interplay of aging dynamics and cell-to-cell variability.

264 tivation program, coupled with a decrease in cell-to-cell variability.

265 to be lower than in vitro, with significant cell-to-cell variability.

266 y, the presence of multiple gene copies, and cell-to-cell variability.

267 gical populations of cells show considerable cell-to-cell variability.

268 sity for calcium oscillations, despite large cell-to-cell variability.

269 -120 mum, which resulted in a high degree of cell-to-cell variance in cytokine exposure.

270 The method is used to measure the cell-to-cell variance of lactate release in K562 leukemi

271 Because of cell to cell variation, it is difficult to obtain statis

272 er devices and electric vehicles, making the cell-to-cell variation (CtCV) a key factor to consider i

273 the consequences of such errors in terms of cell-to-cell variation have never been demonstrated by e

274 suggesting cell cycle-independent origin of cell-to-cell variation in Ccnb1 promoter activation.

275 to greater samples is revealing substantial cell-to-cell variation in expression levels and propagat

276 repressive complex-active genes have greater cell-to-cell variation in expression than active genes,

277 ribed genes with Polycomb marks have greater cell-to-cell variation in expression.

278 Cell-to-cell variation in gene expression levels (noise)

279 rameters or assume that there is significant cell-to-cell variation in key parameters like cell-cell

280 tern blotting on individual cells to measure cell-to-cell variation in protein expression levels and

281 we show collective chemotaxis is limited by cell-to-cell variation in signaling.

282 There is wide cell-to-cell variation in the expressions of these recep

283 d that the precision is remarkably high: the cell-to-cell variation in the transverse position of the

284 um polymer model that can accurately predict cell-to-cell variation of chromosome conformation within

285 Here we report that CTCF decreases cell-to-cell variation of expression by stabilizing enha

286 promoter structure critically influences the cell-to-cell variation of gene expression in bacteria an

287 TCF plays important roles in controlling the cell-to-cell variation of gene expression in mammalian c

288 of a CTCF binding site results in increased cell-to-cell variation of gene expression, indicating th

289 onitor tumor heterogeneity, but estimates of cell-to-cell variation typically fail to account for the

290 : We derive a link between cluster accuracy, cell-to-cell variation, and the cluster rheology.

291 owerful method to investigate transcriptomic cell-to-cell variation, thereby revealing new cell types

292 ploits the additional information present in cell-to-cell variation, without requiring model paramete

293 tional contributions to noise by determining cell-to-cell variations in the abundance of mRNA and rep

294 We found significant cell-to-cell variations in the molecular profiles of org

295 marked by emergence of slow kinetics, large cell-to-cell variations of copy numbers, temporally corr

296 transfer of a "selfish" genetic element from cell to cell via membrane fusion.

297 t virological synapses, thereby facilitating cell-to-cell viral transmission.

298 the extracellular milieu but may not inhibit cell-to-cell virus transmission.

299 on of alpha4beta7(high) T cells and promotes cell-to-cell virus transmission.

300 To both enter host cells and spread from cell to cell within infected hosts, the vast majority of