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1 mic infection in a physiologically relevant, cellular context.
2 GRP78 and that both proteins interact in the cellular context.
3 ng of transcription factors (TFs) in a given cellular context.
4 nd anti-tumorigenic signaling depending upon cellular context.
5 nts also shows the same selectivity within a cellular context.
6 ligands that target G-quadruplexes within a cellular context.
7 that Rasip1 interacts with active Rap1 in a cellular context.
8 ng activities are likely to be relevant in a cellular context.
9 s and paths under specific environmental and cellular context.
10 or suppress signaling depending on the local cellular context.
11 f deleterious consequences, depending on the cellular context.
12 target one of the eleven human caspases in a cellular context.
13 cles act as landmarks and offer clarity in a cellular context.
14 d interpretation of nuclear transport in the cellular context.
15 alysis of the viral replication steps in the cellular context.
16 cer is complex and may vary depending on the cellular context.
17 ner strictly dependent by its expression and cellular context.
18 ctional role in macromolecular activity in a cellular context.
19 chaperones by altering the environment in a cellular context.
20 and requires just one receptor regardless of cellular context.
21 ficity of smAKAP for PKA-RIalpha/beta in the cellular context.
22 eins with respect to one another in a native cellular context.
23 l death or differentiation, depending on the cellular context.
24 hoid and myeloid progenitors autonomously of cellular context.
25 mechanisms driving membrane deformation in a cellular context.
26 mall ensembles or behave processively in the cellular context.
27 r Cyclin B in regulating replication in this cellular context.
28 bit tumourigenic processes, depending on the cellular context.
29 nd anti-metastatic function depending on the cellular context.
30 or suppressive or oncogenic depending on the cellular context.
31 e or inhibit tumorigenesis, depending on the cellular context.
32 strains of mice to be placed into a coherent cellular context.
33 ts or promotes angiogenesis depending on the cellular context.
34 icity of complex formation in vitro and in a cellular context.
35 ein molecules both in isolation and in their cellular context.
36 posing mechanisms of action depending on the cellular context.
37 mporal control of BMP signaling in the right cellular context.
38 ors of signalling pathways, depending on the cellular context.
39 nogenesis or neurodegeneration, depending on cellular context.
40 of protein function and its application in a cellular context.
41 uppressors, host susceptibility factors, and cellular context.
42 factor receptor-bound protein 2 (Grb2) in a cellular context.
43 otein-coupled receptor (GPCR) signaling in a cellular context.
44 sily detect different levels of editing in a cellular context.
45 crucial to describing their functions in the cellular context.
46 e arrest function of p21 is dependent on the cellular context.
47 ypes is usually restricted and is defined by cellular context.
48 osed complexes containing hAgo2 or their sub-cellular context.
49 modulators of TF activity within a specific cellular context.
50 vivo and suggest that its effects depend on cellular context.
51 unctionally interrelated pathways in a given cellular context.
52 components relate to one another within the cellular context.
53 nding transcription factors depending on the cellular context.
54 slational modulation of mammalian TFs in any cellular context.
55 tem to observe single-molecule motility in a cellular context.
56 nal activator or repressor, depending on the cellular context.
57 t, by RNAi-mediated knockdown of p53 in this cellular context.
58 nt and p53-independent manners, depending on cellular context.
59 aB1-crystallin promoter changes depending on cellular context.
60 ation of individual GPCR subtypes in defined cellular context.
61 ave and activate pro-MSP-1 in vitro and in a cellular context.
62 ed DNA damage in human cells are affected by cellular context.
63 erstanding of the function of a protein in a cellular context.
64 ocytosis in varying degrees depending on the cellular context.
65 ation is poorly defined, particularly in the cellular context.
66 nd growth, contingent upon the molecular and cellular context.
67 s in tumor progression that are dependent on cellular context.
68 profile numerous RNA species in their native cellular context.
69 to understand gene function in a particular cellular context.
70 ss or promote tumorigenesis depending on the cellular context.
71 his organelle and to probe its behavior in a cellular context.
72 ization and interaction networks in a native cellular context.
73 aling and neuronal glucose metabolism in the cellular context.
74 ponding full-length proteins in their native cellular context.
75 on both the brightness of the focus, and the cellular context.
76 ecome active enhancers given the appropriate cellular context.
77 ure to optimize metabolic processes within a cellular context.
78 ppressor or tumour promoter depending on the cellular context.
79 e clock fits within and influences a broader cellular context.
80 f what can constitute an active protein in a cellular context.
81 ulatory activity in a co-transcriptional and cellular context.
82 B isoforms and modulation of the target in a cellular context.
83 d what functional roles they play depends on cellular context.
84 ously appreciated and is highly dependent on cellular context.
85 hinery for contraction that acts in multiple cellular contexts.
86 and and outwit adaptation in a wide range of cellular contexts.
87 utant Puma on cell viability in a variety of cellular contexts.
88 tablishing excitable actin dynamics in other cellular contexts.
89 mine GATA1 function in biologically relevant cellular contexts.
90 cting partners of target proteins in diverse cellular contexts.
91 n cycles, pathways, and networks in multiple cellular contexts.
92 gulation of a target transcript in different cellular contexts.
93 ntify energy metabolism in a wide variety of cellular contexts.
94 he function of specific cells within complex cellular contexts.
95 s share signalling pathways across different cellular contexts.
96 of endogenous methyltransferases in diverse cellular contexts.
97 pact on stimulus-secretion coupling in wider cellular contexts.
98 e accurate and restricted to the appropriate cellular contexts.
99 ance of studying miRNA function in different cellular contexts.
100 displaces transcription ECs in a variety of cellular contexts.
101 by analyzing chromatin features in different cellular contexts.
102 such reiteratively used factors in different cellular contexts.
103 and critical component of the PQC in several cellular contexts.
104 ectivity of regulatory networks in different cellular contexts.
105 hysiological responses observed in different cellular contexts.
106 iated double-strand breaks (DSBs) in several cellular contexts.
107 bly may regulate the cytoskeleton in dynamic cellular contexts.
108 onal redundancy for PKD1 and PKD2 in various cellular contexts.
109 ositive factor for Notch activity in several cellular contexts.
110 protein levels and Wnt signaling in several cellular contexts.
111 ures expression of pUL138 under a variety of cellular contexts.
112 ent to activate the dopamine pathway in some cellular contexts.
113 cell polarity (Wnt/PCP) pathway, in certain cellular contexts.
114 lex to promote Notch signaling in particular cellular contexts.
115 mutations evaluated in both biochemical and cellular contexts.
116 e variants in their physiologically relevant cellular contexts.
117 r to native G(i/o) signaling pathways in all cellular contexts.
118 ion to elicit diverse responses in different cellular contexts.
119 Ks, producing distinct outcomes in different cellular contexts.
120 ing the specificity of outcomes in different cellular contexts.
121 enzyme and a signaling cofactor in different cellular contexts.
122 ic and anti-oncogenic phenotypes in specific cellular contexts.
123 ch TF to control gene expression in specific cellular contexts.
124 ionarily conserved genetic module in diverse cellular contexts.
125 network is precisely controlled in different cellular contexts.
126 ts precise gene expression levels in varying cellular contexts.
127 red following ligand engagement in different cellular contexts.
128 ys to monitor DUB activities in vitro and in cellular contexts.
129 s in cell-to-cell communication in different cellular contexts.
130 ell models, encompassing hepatic and mammary cellular contexts.
131 of protein-specific glycosylation in various cellular contexts.
132 umor suppressive functions acting in diverse cellular contexts.
133 hances the loss of miRNA function in diverse cellular contexts.
134 portant transcriptional regulator in diverse cellular contexts.
135 he engineering of BMCs for new functions and cellular contexts.
136 sensor of mechanical stimulation in diverse cellular contexts.
137 r capable of membrane remodeling in multiple cellular contexts.
138 transduction molecules that are modified by cellular context?
140 and signal processing of this pathway in the cellular context, a genetically encoded, fluorescent pro
142 mic elements, these results suggest that the cellular context also determines susceptibility to PyV m
143 tions of complex molecular machines in their cellular context and at atomic resolution is of prime im
146 chain precedes disulfide formation within a cellular context and highlights key differences between
147 ly, we discuss disulfide bond formation in a cellular context and identify important principles that
148 olution, and underline the importance of the cellular context and integrated approaches for understan
149 assumes opposite functions depending on the cellular context and its posttranslational modifications
150 ot potent tyrosine kinase activators in this cellular context and that a significant proportion of no
151 xical, effects on viability depending on the cellular context and that EphA2 mediates a delicate bala
154 iption in a manner that is dependent on both cellular context and the specific downstream target.
158 ole of space and spatial control in multiple cellular contexts and a basis for engineering spatial co
161 s two homologs, p63 and p73, that in various cellular contexts and stresses contribute to this proces
162 ters that are differentially used in various cellular contexts and tissue types add to the transcript
164 on of FGF2 mediated by Tec in vitro and in a cellular context, and (iii) unconventional secretion of
166 assay was used to validate the results in a cellular context, and peptide insertions were modeled us
167 this bias can vary depending on location and cellular context, and that DSB frequency is not the only
168 ponse threshold is determined by the rGC and cellular context, and that multiple domains contribute t
169 n of reiteratively used factors in different cellular contexts, and an important strategy for doing s
171 in p53-independent pathways under different cellular contexts, and its effects on transcriptional fa
172 xpressed, autophagy can occur in specialized cellular contexts, and mechanisms underlying cell-type-s
173 unctional adaptability of Smads in different cellular contexts, and their dependence on lineage-deter
174 biologic activity across a broad sampling of cellular contexts, as opposed to extrapolating from resu
175 eolytic activity; and that, depending on the cellular context, Atg7 represses the apoptotic capabilit
179 he Notch pathway on proliferation depends on cellular context, being growth promotion in some, includ
180 n of these interactions within their correct cellular context both at high resolution and in real tim
181 led that the dyes are functional in multiple cellular contexts, both on the cell surface and within t
182 upramolecular assemblies and organelles in a cellular context, but image degradation, caused by scatt
183 ic acid also induces differentiation in many cellular contexts, but its mechanism of action in relati
184 ains of SALS with actin must be tuned in the cellular context by other modules of the protein and/or
186 gested as an eat-me signal in dead and dying cellular contexts, can also promote phagocytic uptake of
188 acterization confirmed high dual efficacy in cellular context combined with low toxicity, and pilot i
191 ly on their local genomic environment and on cellular context, complicating experimental analysis of
192 RNA (hTR), not previously characterized in a cellular context, comprised of several guanosine tracts
194 ns of membrane-permeant small molecules in a cellular context could facilitate development of site-di
196 ted with human cancers and Tp53 deletion has cellular context dependent effects upon lymphocyte trans
199 Galectins are proteins involved in diverse cellular contexts due to their capacity to decipher and
201 inactivation of ARF and reveal an important cellular context for genetic and viral inactivation of T
203 at GR is required to establish the necessary cellular context for maintaining normal uterine biology
204 affect gene expression can vary in different cellular contexts, for example between different subtype
205 lipids in single extracts, lose the original cellular context from which these lipids are derived.
206 uncoupling cell size from a developmental or cellular context has proven experimentally challenging.
207 f the modulation of the pathway in different cellular contexts has revealed many layers of regulation
210 are elicited by Wnt stimulation in different cellular contexts; however, mechanisms that confer conte
212 t Src that was constitutively activated in a cellular context (IC(50) = 2.12 muM) compared with the i
214 development-with its resulting diversity of cellular contexts-impacts miRNA regulation is unclear.
216 er, our findings highlight the importance of cellular context in assigning growth properties to growt
219 demonstrate the importance of molecular and cellular context in oncogenic transformation and acquisi
222 uences of their signaling crosstalk in multi-cellular context in vivo remain largely unknown, especia
226 murine macrophages and also suggest that the cellular context in which P2X(7)R signaling occurs diffe
227 ologous genes is primarily determined by the cellular context in which the genes act, explaining why
228 al selectivity of Mur and Fur depends on the cellular context in which they function, not on intrinsi
230 ation, and thus provide a convenient in vivo cellular context in which to address this question.
231 ensitive to functional inhibition by SC66 in cellular contexts in which the PI3K inhibition has littl
232 eolysis in two entirely distinct protein and cellular contexts, in one case participating in bacterio
233 he establishment of cell polarity in various cellular contexts, including axis-pattern formation in t
234 ral to establishing cell polarity in various cellular contexts, including during messenger ribonuclei
235 rotein PAR-1 plays an essential role in many cellular contexts, including embryogenesis, asymmetric c
239 CC hyperplasia and GIST, suggesting that the cellular context is important for KIT to mediate oncogen
240 standing which promoter is employed in which cellular context is required to unravel gene regulatory
242 R and FOXA1 binding events in drug-resistant cellular contexts is supported by histological co-expres
245 m this study highlight the importance of the cellular context of different cancer cells for the funct
248 ons suggest that the duration, intensity and cellular context of FGFR signaling during growth plate c
253 sed the impact of epigenetic alterations and cellular context on functional and transcriptional repro
255 o adjust its lytic program to suit different cellular contexts or interpret signals from the outside.
256 recognition receptor signaling under certain cellular contexts, or in response to some viral and bact
257 observe may be dependent on experimental or cellular context, our results suggest that gene promoter
259 Depending on the differentiation factor and cellular context, pRb can either suppress or promote the
260 gnal strength, timing, spatial location, and cellular context promote specific cell-fate decisions re
261 ed antigens in their native conformation and cellular context, provide a rich source of novel antigen
262 Our results indicate that within the same cellular context, RAS can exert different, even antagoni
263 sults reveal a regulatory principle by which cellular context regulates Akt protein dynamics, which d
267 nes to certain target cells and differential cellular context-specific requirements for oncogenic tra
268 a damage-gated molecular switch that governs cellular-context-specific cell fate decisions in respons
269 at interpret an enhancer sequence in a given cellular context specified by transcription factor conce
270 ome of enhanced gene disruption depends upon cellular context, stimulating deletion of genomic sequen
271 principle experiments demonstrated that in a cellular context, SUBINs largely prevent heat shock-trig
272 he body; it has different roles in different cellular contexts, such as oncogenic and tumor-suppresso
274 ns are generally more specific to particular cellular contexts than are single agent activities.
275 ly modulating p53 activity, Oct-4 provides a cellular context that augments the proapoptotic activity
278 ause G(1) arrest in some cells, but in other cellular contexts, the downstream cyclin E protein can s
279 y osteolysis, but regardless of etiology and cellular contexts, the osteoclast is the bone-degrading
280 made in defining the role of APC in a normal cellular context, there are still significant gaps in ou
281 pecific regulatory factors in many different cellular contexts, thereby revealing the fundamental pri
282 ontaining ETS or AP1 motifs depending on the cellular context, thus indicating new approaches for mod
283 the application of stabilizing ligands in a cellular context to target G-quadruplexes and intervene
285 purified proteins, and was verified within a cellular context using induced overexpression and activa
287 fficiency to quantify protein copy number in cellular contexts using super-resolution microscopy.
288 ectrode surface, mimicking TLR-4's role in a cellular context, was essential in producing a responsiv
289 3D arrangement of prion assemblies in their cellular context, we examined yeast [PSI(+)] prions in t
290 reactive oxygen species (ROS) in its native cellular context, we now present a new method for monito
293 diverse biological effects depending on the cellular context where Notch receptors are activated.
294 of genetic regulation of gene expression by cellular context, which relates to cell-type-specific DN
296 lk, our work indicates that consideration of cellular context will likely be crucial for targeting si
298 a stable form that RNAP III can access in a cellular context with, in some cases, near promoter-like
299 nsights into how proteins are organized in a cellular context, with a spatial resolution approaching
300 oscopic images of specific proteins in their cellular context yield important insights into biologica
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