ライフサイエンスコーパス: cellular immune response

1 echnique did, however, provoke a significant cellular immune response.

2 -HDM induced an antibody response, besides a cellular immune response.

3 d tumor death induces a long-term anti-tumor cellular immune response.

4 emic infection and that this depended on the cellular immune response.

5 primary infection, thereby compromising the cellular immune response.

6 ificant effects of ISG15 modification on the cellular immune response.

7 cium burst is required for activation of the cellular immune response.

8 TBE high responders in terms of humoral and cellular immune response.

9 adaptive immune cells, while modulating the cellular immune response.

10 ule that is used to study both facets of the cellular immune response.

11 nt had any effect on an antitumor humoral or cellular immune response.

12 cell receptors (TcRs) play a central role in cellular immune response.

13 erapy show signs of a particularly efficient cellular immune response.

14 antioxidants and offspring that had reduced cellular immune response.

15 C is critical for the effective induction of cellular immune responses.

16 agglutinin antibody responses, but different cellular immune responses.

17 mmunological synapse formation, and numerous cellular immune responses.

18 a-tumor heterogeneity and dissecting complex cellular immune responses.

19 ion of additional genes that are involved in cellular immune responses.

20 MGN1703 dosing, suggesting an enhancement of cellular immune responses.

21 ed the induction of SIV-specific humoral and cellular immune responses.

22 ylceramide adjuvant, though adjuvant reduced cellular immune responses.

23 ut rather is due to compromised local innate cellular immune responses.

24 in the T4 head elicited robust antibody and cellular immune responses.

25 as the detection of Ag-specific humoral and cellular immune responses.

26 ncluding downregulation of cytokine-mediated cellular immune responses.

27 ellular pathogens requires the generation of cellular immune responses.

28 he magnitude and duration of both innate and cellular immune responses.

29 accine candidates targeting both humoral and cellular immune responses.

30 l transmission may require IgA antibodies or cellular immune responses.

31 purified, and used for the human humoral and cellular immune responses.

32 essential for the development of humoral and cellular immune responses.

33 is a strong adjuvant capable of stimulating cellular immune responses.

34 ion representing the extremes of humoral and cellular immune responses.

35 HHV-6 and provide a basis for tracking HHV-6 cellular immune responses.

36 ducing strong transgene-specific humoral and cellular immune responses.

37 catarrhalis strains by eliciting humoral and cellular immune responses.

38 ed AGMs also displayed robust virus-specific cellular immune responses.

39 nal design of new vaccines that aim to prime cellular immune responses.

40 e activation of both intrahepatic innate and cellular immune responses.

41 y dendritic cells (DC) in vitro that inhibit cellular immune responses.

42 l habitats by environmental chemistry and by cellular immune responses.

43 velopment of the protective Mtb-specific Th1 cellular immune responses.

44 tes because they can elicit both humoral and cellular immune responses.

45 g broadly reactive neutralizing antibody and cellular immune responses.

46 T effector function and the perpetuation of cellular immune responses.

47 in minimal to no effect on vaccine-elicited cellular immune responses.

48 IV-1-infected rodents develop virus-specific cellular immune responses.

49 ession enhanced the induction of Ag-specific cellular immune responses.

50 le safety profile and stimulated humoral and cellular immune responses.

51 y of the decidua to mount appropriate innate cellular immune responses.

52 mice results in strong antiviral humoral and cellular immune responses.

53 NA vaccination influences the quality of the cellular immune responses.

54 t subset of pDCs specialized in coordinating cellular immune responses.

55 ct type III IFN signaling and virus-specific cellular immune responses.

56 ed and elicited antigen-specific humoral and cellular immune responses.

57 the complexity of the mechanisms regulating cellular immune responses.

58 +) T cells mediate antigen-specific adaptive cellular immune responses.

59 vel type of vaccine elicits both humoral and cellular immune responses.

60 has been associated with quicker recovery of cellular immune responses after ART initiation and early

61 pression, and enhanced primary and secondary cellular immune responses after mCMV infection than did

62 particularly gammadelta T cells) in the host cellular immune response against AIM and CAEBV.

63 a1-15 or Abeta1-40/42 peptides, indicating a cellular immune response against DT while avoiding an Ab

64 ys were concordant and demonstrated that the cellular immune response against JCV is associated with

65 h p24-SIgA elicits both a strong humoral and cellular immune response against p24 at the systemic and

66 ells that sense DV infection and amplify the cellular immune response against this virus in an IL-18-

67 and FIX concentrate use, without detectable cellular immune responses against capsids.

68 of arthritis were recorded, and humoral and cellular immune responses against CII were analyzed.

69 In addition, humoral and cellular immune responses against EBOV glycoprotein were

70 Here, we investigated whether cellular immune responses against HIV-1 include such T m

71 Mice generated both humoral and cellular immune responses against JCV.

72 with chronic inflammation and a lack of the cellular immune responses against Leishmania.

73 Cellular immune responses against NS5 were also elicited

74 ctivate the innate immune system and improve cellular immune responses against rAd5-expressed Ags, in

75 liminating HIV-1-infected cells by targeting cellular immune responses against stable human endogenou

76 Creating immunogens that can elicit cellular immune responses against the genetically varied

77 accination with ENO1 DNA elicits humoral and cellular immune responses against tumors, delays tumor p

78 of truncated variants in the major target of cellular immune responses all parallel what are seen wit

79 cant enrichment of nervous system signaling, cellular immune response and cytokine signaling pathways

80 proteins responsible for the aforementioned cellular immune response and IFN-gamma production.

81 there may be considerable differences in the cellular immune response and regulatory mechanisms induc

82 HVEM regulates cellular immune responses and can also increase cell sur

83 ng vaccination largely reflects Gag-specific cellular immune responses and correlates with in vivo vi

84 ally and systemically via stimulation of CD8 cellular immune responses and highlight a conserved role

85 of HIV-specific T-cell immunity and identify cellular immune responses and individual cytokines as po

86 lly with coated spores developed humoral and cellular immune responses and multifunctional T cells an

87 noregulatory capacity through suppression of cellular immune responses and production of anti-inflamm

88 functions during liver damage that regulate cellular immune responses and promote hepatocyte death.

89 ty of our candidate dengue vaccine to elicit cellular immune responses and support the further evalua

90 We aimed to define anti-ADH cellular immune responses and their association with act

91 ace oligosaccharides are sufficient to alter cellular immune responses and thereby let a pathogen hid

92 clearance, subsequent emergence of a potent cellular immune response, and the effect of these on liv

93 Antibody, cellular immune responses, and epitope specificity in se

94 line by 2 weeks postinfection, no detectable cellular immune responses, and limited or no spread to p

95 the gastrointestinal tract, gastrointestinal cellular immune responses, and protection against a muco

96 acid sequences that are the major targets of cellular immune responses, and the emergence in vivo of

97 cination induced potent innate, humoral, and cellular immune responses, and the mutant could protect

98 4 elicited significantly greater humoral and cellular immune responses, and the RASV chi11021 strain

99 mistry and sexual hormone levels and reduced cellular immune response, antioxidant levels, and carote

100 Innate cellular immune responses are a critical first-line defe

101 racellular pathogens, where both humoral and cellular immune responses are desired.

102 ely aspect of this failure is that antiviral cellular immune responses are either absent or present a

103 We conclude that local cellular immune responses are important for protection a

104 e, suggesting that the age-associated skewed cellular immune responses are reversible.

105 Humoral and cellular immune responses are seen in both models after

106 Broadly targeted cellular immune responses are thought to be important fo

107 While humoral and cellular immune responses are well described in peripher

108 We hypothesized that innate cellular immune responses at the site of infection would

109 not appear to be required to counteract the cellular immune response but are needed for the coloniza

110 facilitates lytic infection, modulating the cellular immune response by interacting with viral and c

111 we show that bacterial infection induces the cellular immune response by modulating occluding-junctio

112 the HSV-1 LAT locus interferes with the host cellular immune response by shaping a broader repertoire

113 e Varroa mite, adversely affects humoral and cellular immune responses by interfering with NF-kappaB

114 signaling requirements for the generation of cellular immune responses by intramuscular immunization

115 es an ability to potently induce humoral and cellular immune responses by use of highly attenuated an

116 In addition, all groups generated a cellular immune response characterized by antigen-specif

117 ted in induction of both innate and adaptive cellular immune responses characterized by a predominanc

118 potent functional neutralizing antibody and cellular immune responses, characterized by HA-specific

119 cination with VC2-EHV-1-gD stimulated strong cellular immune responses, characterized by the upregula

120 r intradermally (i.d.) developed humoral and cellular immune responses comparable to those of mice im

121 tantially increased magnitude and breadth of cellular immune responses compared with conserved-region

122 atitis C virus (HCV) kinetics indicated that cellular immune responses contribute to interferon (IFN)

123 It is unknown to what extent cellular immune responses contribute to liver disease an

124 Thus, insufficient innate cytokine and cellular immune responses contribute to the unique susce

125 s in unvaccinated individuals, when a strong cellular immune response controls early infection.

126 The breadth of cellular immune responses correlated inversely with set

127 ture and, following infection, flies mount a cellular immune response culminating in the cellular enc

128 d coworkers report evidence that preexisting cellular immune responses directed toward Ad5 reduce the

129 ssessing the risk of CMV infection, although cellular immune responses driven by CMV-specific CD4 and

130 to explore the coevolution of virus and the cellular immune response during primary infection.

131 esenting a unique opportunity to examine the cellular immune responses during acute Ebola virus infec

132 Understanding the initiation of cellular immune responses during blood-stage malaria inf

133 This study demonstrates that cattle mount cellular immune responses during colonization with EHEC

134 To characterize cellular immune responses during recovery, we analyzed t

135 aracterize in greater detail the humoral and cellular immune responses elicited by Ad26.ENVA.01 in hu

136 The humoral and cellular immune responses elicited by the trivalent live

137 Therefore, the cellular immune response evolves during MeV clearance to

138 CD8(+) T cells and are essential for optimal cellular immune responses following immunization with pl

139 We now characterize the cellular immune response from 20 donors against 5 major

140 Similarly, cellular immune responses from a subset of subjects and

141 ition of the heterogeneity and complexity of cellular immune responses generated by different vaccine

142 igens are used as a surrogate for endogenous cellular immune responses generated during infection.

143 the success and failure of the HIV-specific cellular immune response has implications that extend no

144 an adenovirus-based approach to induce only cellular immune responses, has been replaced by cautious

145 spp., where protection is likely mediated by cellular immune responses, has proven elusive.

146 n and vaccination, efforts to understand the cellular immune response have been severely hampered by

147 l trials have shown that both antibodies and cellular immune responses have been correlated with prot

148 Cellular immune responses have been repeatedly associate

149 10 and their overall influence on innate and cellular immune responses have not been well characteriz

150 Cellular immune responses have the potential to elicit d

151 the MNP boost showed significantly enhanced cellular immune responses, hemagglutination-inhibition (

152 depletion of DCs significantly dampened the cellular immune response (IFN-gamma(+)CD8(+) T cells) ag

153 gest that this property influences antiviral cellular immune responses.IMPORTANCE Primate lentiviruse

154 The induction of a potent humoral and cellular immune response in mucosal tissue is important

155 apies and vaccines for HIV-1 but also to the cellular immune response in other disease states.

156 To assess the viral targets of the cellular immune response in STLV-1-infected animals, we

157 No data are available on the cellular immune response in the acute phase of human ZIK

158 Detailed analysis of the cellular immune response in tumours has the potential to

159 type humoral immune responses in 40%-50% and cellular immune responses in 50%-75% of follicular lymph

160 There is little information on cellular immune responses in asymptomatic parasite carri

161 Here we describe cellular immune responses in baboons against a closely r

162 The induction of potent and durable cellular immune responses in both peripheral and mucosal

163 via lymph is critical for the generation of cellular immune responses in draining lymph nodes (LNs).

164 crobial pathogens involves the activation of cellular immune responses in eukaryotes, and this cellul

165 monstrate here the induction of SIV-specific cellular immune responses in foreskin by adenovirus sero

166 ygosity and protective antigen (PA)-specific cellular immune responses in healthy subjects following

167 ed breadth and magnitude of MHC-B-restricted cellular immune responses in HIV-infected individuals.

168 the RSV-specific human innate, humoral, and cellular immune responses in humanized mice (mice with a

169 01 elicited a broad diversity of humoral and cellular immune responses in humans.

170 etry enables highly multiplexed profiling of cellular immune responses in limited-volume samples, adv

171 le vaccination generated robust antibody and cellular immune responses in mice that provided complete

172 This vaccine stimulated strong humoral and cellular immune responses in mice, suggesting that it co

173 Nonlive vaccine platforms that induce potent cellular immune responses in mucosal tissue would have b

174 All regimens elicited humoral and cellular immune responses in nearly all participants.

175 n regarding the role of chemokines and early cellular immune responses in protective immunity to pulm

176 ay of birth elicited detectable Gag-specific cellular immune responses in rhesus monkeys, but these r

177 A trend to more durable cellular immune responses in T5 was observed at 1 year (

178 ic role of CD39 in the kinetic regulation of cellular immune responses in the evolution of disease.

179 Also, there were enhanced cellular immune responses in the group received adjuvant

180 rowth transforming ability, induces multiple cellular immune responses in the infected host.

181 o generate a safe replicative body to escape cellular immune responses in the insect gut.

182 ystemic and mucosal Env-specific humoral and cellular immune responses in the majority of subjects.

183 study, we compared antiparasite humoral and cellular immune responses in two cohorts of malaria-naiv

184 in the magnitude and breadth of SIV-specific cellular immune responses in virologically suppressed, S

185 y suitable for non-invasive field studies of cellular immune responses in wild large mammals.

186 ary coccidioidomycosis demonstrated specific cellular immune responses, including expression of IL-17

187 this study were: 1) to quantify the in vivo cellular immune response induced by AS01 in an outbred o

188 Here, we analyzed human cellular immune responses induced by a single dose of th

189 ere we describe new findings on the range of cellular immune responses induced by EBV infection, on v

190 Env-specific cellular immune responses induced by the vaccine include

191 The cellular immune responses induced by the vaccine were ge

192 tages in a vaccine setting, eliciting strong cellular immune responses involving both CD8(+) and CD4(

193 It is known that vigorous and multispecific cellular immune responses, involving both helper CD4(+)

194 preservation or restoration of HIV-specific cellular immune response is a major goal of AIDS treatme

195 the development of a fetal-specific adaptive cellular immune response is a normal consequence of huma

196 Although the host cellular immune response is critical to the control of t

197 ppling the immune system before an effective cellular immune response is developed and active.

198 Although the cellular immune response is essential for controlling SI

199 JCV-specific cellular immune response is highly prevalent in all JCV-

200 ne that would stimulate both the humoral and cellular immune responses leading to long-lived memory.

201 findings show that the induction of a strong cellular immune response may limit antibody responses in

202 Thus, the factors defining protective cellular immune responses may be more complex than simpl

203 tanding the coordination between humoral and cellular immune responses may be the key to developing p

204 which are not sufficient for augmenting the cellular immune response, notably, HVRs I, II, and V.

205 The cellular immune responses observed in the lower airways

206 ls (Tregs) are an essential component of the cellular immune response, occupying a key role in mainta

207 We then characterized the cellular immune response of 59 cases of POT and 4 cases

208 m future vaccine development, we studied the cellular immune responses of cattle during EHEC O157:H7

209 d HIV-1 sequences that are aimed at focusing cellular immune responses on these potentially critical

210 modeling, arrhythmogenicity, activation of a cellular immune response, or off-target organ damage by

211 thelial cells and has the potential to alter cellular immune responses, platelet activation, and endo

212 The cellular immune response plays a critical role in contro

213 We first show that the cellular immune response plays an important role in regu

214 sion of NASH by stimulating both humoral and cellular immune responses, pointing to the possible role

215 nd examined recipients' CMV antigen-specific cellular immune responses primed directly by donor cells

216 notype, and polyfunctional pathogen-specific cellular immune responses prior to and 4 weeks after ART

217 Mucosal and cellular immune responses remain poorly understood, with

218 a biochemistry, carotenoid-based coloration, cellular immune response, steroid hormone levels, and re

219 he most likely reasons that the HIV-specific cellular immune response succeeds in a small number of p

220 mulated a significantly stronger humoral and cellular immune response than baculovirus-expressed VLP

221 l loads and earlier and stronger humoral and cellular immune responses than controls.

222 ion, WT mice mounted more robust humoral and cellular immune responses than HLA-DR4 mice.

223 geneic glioma models involves a multifaceted cellular immune response that can be overcome with cyclo

224 theless, all animals generated a humoral and cellular immune response that conferred partial cross-pr

225 loped a comprehensive computational model of cellular immune response that elucidates its mechanism a

226 that model further, we uncovered an altered cellular immune response that promotes the recruitment o

227 cross-reactive ELISA antibodies and a robust cellular immune response that was also associated with c

228 oach is to design a vaccine that will elicit cellular immune responses that are focused on highly con

229 wever, the role that hBDs have in initiating cellular immune responses that contribute to antigen-spe

230 cal screening are targets of multifunctional cellular immune responses that correlate with protection

231 The cellular immune responses that protect against tuberculo

232 Cellular immune responses that protect against tumors ty

233 atural strains of HIV are designed to induce cellular immune responses that recognize genetically div

234 iators provides a link between metabolic and cellular immune responses that result in the Th1-mediate

235 LC16m8 produced robust cellular immune responses that trended higher than Dryva

236 The HIV SAM vaccine induced potent cellular immune responses that were greater in magnitude

237 ral gene product that is the major target of cellular immune responses, the persistence of viral amin

238 pply of peptides recognized by the antiviral cellular immune response, thereby facilitating immunosur

239 bacteria, and protozoan parasites, suppress cellular immune responses through activation of type I I

240 cgammaRs) play critical roles in humoral and cellular immune responses through interactions with the

241 We now characterize the cellular immune response to all 7 PIV3-encoded antigens

242 amma (IFNgamma) ELISpot assays to assess the cellular immune response to blood-stage and pre-erythroc

243 deficient mice exhibit an intact humoral and cellular immune response to collagen and yet have a redu

244 We report an analysis of cellular immune response to component Ags of RTS,S-hepat

245 erstanding of the targets and outcome of the cellular immune response to HHV-6 makes it difficult to

246 The cellular immune response to HIV-1 has now been studied i

247 ls represent a long-lasting component of the cellular immune response to HIV-1 that persists in an an

248 Tissue damage is attributed to the cellular immune response to HTLV-1-infected lymphocytes.

249 Consistent with this observation, the cellular immune response to infection was characterized

250 sensing of viral DNA is an essential step of cellular immune response to infections with DNA viruses.

251 g IFN-gamma and IL-17A production during the cellular immune response to M. tuberculosis.

252 A-heterozygous individuals generate stronger cellular immune response to other virulence factors (Bac

253 n of Ag-specific memory Tregs that shape the cellular immune response to secondary influenza virus ch

254 nd virus mutations that lead to emergence of cellular immune response to the mutant virus.

255 Thus, we characterized the cellular immune response to the virus and identified F,

256 cellular immunity, we wanted to compare the cellular immune response to this challenge strain to the

257 Understanding the cellular immune response to this infection is important

258 or hemophilia B (HB) showed that the risk of cellular immune response to vector capsid is clearly dos

259 duce stronger effector memory T cell-biased, cellular immune responses to a coexpressed Ag despite pr

260 was required for early innate and subsequent cellular immune responses to a model IMX vaccine.

261 Cellular immune responses to all particle-based vaccine

262 and, CD70, has been implicated in regulating cellular immune responses to cancer.

263 o generated robust neutralizing antibody and cellular immune responses to CHIKV in mice after a singl

264 significantly enhances adaptive antibody and cellular immune responses to codelivered antigens.

265 The humoral and cellular immune responses to DBs were compared to the im

266 Cellular immune responses to envelope protein EnvA pepti

267 Cellular immune responses to gD-2 did not correlate with

268 he rAd5-EAT-2 vaccine can also induce potent cellular immune responses to HIV-1 Ags despite the prese

269 though we now have a detailed picture of the cellular immune responses to HIV-1, important questions

270 Secondary outcomes were humoral and cellular immune responses to immunization, as assessed b

271 Robust cellular immune responses to influenza during pregnancy

272 ization of several aspects of the innate and cellular immune responses to Lassa virus.

273 ial cells, and (vi) GT-DB and TFF-DB induced cellular immune responses to multiple HCMV peptides.

274 both ferrets and mice generated humoral and cellular immune responses to MuV-IA infection, no obviou

275 ecipients and among subjects with or without cellular immune responses to mycobacterial antigens.

276 ytokine that is able to suppress or activate cellular immune responses to protect the host from invad

277 7 in the generation of robust, high-affinity cellular immune responses to subunit immunization.

278 es containing such adaptations may undermine cellular immune responses to the incoming virus in futur

279 To explore host mechanisms involved in cellular immune responses to the MRKAd5 human immunodefi

280 lutinin 222G viral mutation, and humoral and cellular immune responses to the virus, assessed in hema

281 ion of 3M-052 enhanced antibody and TH1-type cellular immune responses to vaccine antigens for tuberc

282 atory responses and control the magnitude of cellular immune responses to viral infections.

283 ronic HCV infection is characterized by weak cellular immune responses to viral proteins.

284 The cellular immune response toward scaffolds was evaluated

285 olymorphisms and adaptations associated with cellular immune responses, underscoring the complex mole

286 its biological function in the generation of cellular immune responses using cellular prion protein g

287 roups, a positive correlation of humoral and cellular immune response was seen as high/low TBE titers

288 Past the peak of the cellular immune response, we report a gradient of FOXO1

289 100 genes involved in the cellular immune response were sequenced and a missense m

290 Similarly, although potent cellular immune responses were detected against determin

291 Impressive anti-SIV cellular immune responses were elicited on the basis of

292 n strategies eliciting unmatched humoral and cellular immune responses were identified.

293 Cellular immune responses were measured by intracellular

294 roparticles could trigger humoral as well as cellular immune response when administered transdermally

295 k the ability to significantly stimulate the cellular immune response, which is required to prevent t

296 HIV-1 infection leads to the attenuation of cellular immune responses, which has been correlated wit

297 IDS vaccine should elicit strong humoral and cellular immune responses while maintaining low levels o

298 IV Vaccine Trials Network 083 tested whether cellular immune responses with these features are induce

299 oincided with an intense innate and adaptive cellular immune response, with infiltrating leukocytes a

300 uced SIV-specific IgA and IgG antibodies and cellular immune responses within weeks of life.