ライフサイエンスコーパス: cellular immunity

1 ation whether it was evaluated by humoral or cellular immunity.

2 expression, including many genes involved in cellular immunity.

3 erized vector for inducing both antibody and cellular immunity.

4 ials, likely due to inefficient induction of cellular immunity.

5 ing cell 'spreading', an initiating event in cellular immunity.

6 ing CD40 failed to produce either humoral or cellular immunity.

7 elopment of vaccines that efficiently target cellular immunity.

8 tion of balanced Th-1 polarization and Th-17 cellular immunity.

9 hrough chromatinization as part of intrinsic cellular immunity.

10 vant dose for inducing potent and long-lived cellular immunity.

11 esponses but are more limited for generating cellular immunity.

12 conserved receptor that limits and redirects cellular immunity.

13 ensively explored concept aimed at improving cellular immunity.

14 ly therapeutic approach to enhance antiviral cellular immunity.

15 nt (allo-BMT) is controlled by donor-derived cellular immunity.

16 dow of time for the generation of protective cellular immunity.

17 on with heterologous vaccines elicits potent cellular immunity.

18 icity, cross-reactivity, and antigenicity in cellular immunity.

19 chanisms of these drugs and their effects on cellular immunity.

20 by the paucity of information on targets of cellular immunity.

21 spected to protect HIV-1-infected cells from cellular immunity.

22 calcium bursts as an important aspect of fly cellular immunity.

23 vor epigenetic reprogramming and escape from cellular immunity.

24 ox vaccine recipients with severely impaired cellular immunity.

25 valuate kidney damage, humoral immunity, and cellular immunity.

26 activation of Ab-induced innate or adaptive cellular immunity.

27 m which to identify correlates of protective cellular immunity.

28 nd adjuvant followed by NYVAC elicits potent cellular immunity.

29 be an effective vaccine formula in inducing cellular immunity.

30 oute in induction of systemic HIV-1-specific cellular immunity.

31 er therapeutic strategy via up-regulation of cellular immunity.

32 s with concomitant engagement of humoral and cellular immunity.

33 yield greater IL-27 production and sustained cellular immunity.

34 rAd)-based vectors can induce potent mucosal cellular immunity.

35 may benefit parasite escape from humoral and cellular immunity.

36 e overcome through the induction of enhanced cellular immunity.

37 d animals, suggesting an effect of rEV576 on cellular immunity.

38 up, activates NF-kappaB-mediated humoral and cellular immunity.

39 important link between humoral immunity and cellular immunity.

40 eptors (FcR) on APCs can enhance humoral and cellular immunity.

41 athways of innate immunity and induce strong cellular immunity.

42 cterial peritonitis, known to have defective cellular immunity.

43 resulting in enhanced and prolonged effector cellular immunity.

44 se interactions are important in humoral and cellular immunity.

45 icipatory role for this unique population in cellular immunity.

46 cant part of transferred immunity is passive cellular immunity.

47 tes with strong pretransplant donor-reactive cellular immunity.

48 , therefore providing a potential target for cellular immunity.

49 d cell surface to escape recognition by host cellular immunity.

50 as a means to induce Ag-specific humoral and cellular immunity.

51 e that favors development of skin-associated cellular immunity.

52 nstitute a powerful platform for stimulating cellular immunity.

53 PA axis, which modulate spleen shrinkage and cellular immunity.

54 ferentiation and maintenance, of humoral and cellular immunity.

55 ues will facilitate research into protective cellular immunity.

56 role in the regulation of various stages of cellular immunity.

57 ey regulators of measles vaccine humoral and cellular immunity.

58 iferation and plant growth at the expense of cellular immunity.

59 IV B clade fusion protein designed to induce cellular immunity.

60 e development will augment either humoral or cellular immunity.

61 nal immunity" to distinguish it from passive cellular immunity.

62 , who championed the role of phagocytosis in cellular immunity.

63 tibodies, but with no detectable GP-directed cellular immunity.

64 T cell dichotomy is essential for effective cellular immunity.

65 echanism for fine-tuning and optimization of cellular immunity.

66 be used to elicit human anti-RSV humoral and cellular immunity.

67 ovel function for nonhuman TRIM5 variants in cellular immunity.

68 nts a potent vaccine adjuvant of humoral and cellular immunity.

69 Toll-like receptor 9 agonist, which augments cellular immunity.

70 sign HIV-1 vaccines that stimulate effective cellular immunity.

71 s that contain important targets of anti-HIV cellular immunity.

72 comitantly to effector Th cells that support cellular immunity.

73 ent on DCs to stimulate long-term anti-tumor cellular immunity.

74 erving sufficient normal T cells to maintain cellular immunity.

75 responses, and 1V270 potently generates Th1 cellular immunity.

76 stemic corticosteroid therapy, which impairs cellular immunity.

77 e of priming may be a strategy for improving cellular immunity after vaccination.

78 ponses are valuable tools to shape and drive cellular immunity against cancer and intracellular infec

79 which elicited robust humoral, mucosal, and cellular immunity against diverse virus strains.

80 d the potential of pDCs to trigger antiviral cellular immunity against HBV.

81 esponses and suggest that enhancing adaptive cellular immunity against HEV might prevent persistent H

82 latform to induce strong mucosal humoral and cellular immunity against HIV.

83 ) reaction, and induction of serological and cellular immunity against HPV16/18 E7 and KLH were monit

84 ontribute to the induction and activation of cellular immunity against intracellular pathogens, such

85 The cellular immunity against Kaposi's sarcoma-associated he

86 , indicating that MV-NIS treatment triggered cellular immunity against the patients' tumor and sugges

87 magglutinin antigen induction of humoral and cellular immunity against viral challenges.

88 Cellular immunity against viral infection and tumour cel

89 ding cassette (ABC) transporter essential to cellular immunity against viral infection.

90 the unique potential to activate humoral and cellular immunity, an actual challenge is to increase pl

91 both a novel strategy of virus evasion from cellular immunity and a novel role for a cellular protei

92 es with the polyfunctionality and potency of cellular immunity and are a prime example of the potenti

93 dendritic cells (DCs) are key components of cellular immunity and are thought to originate and renew

94 red surprising molecular mechanisms in human cellular immunity and autoimmunity.

95 nfection enabled the development of adaptive cellular immunity and clearance of virus.

96 um suggested that POLR3A mutations triggered cellular immunity and cross-reactive humoral immune resp

97 The microbiome plays an important role in cellular immunity and energy metabolism and has been imp

98 tein boosting, elicited systemic and mucosal cellular immunity and exhibited equivalent, significant

99 e activation, in combination with suppressed cellular immunity and failed cytotoxic T cell anti-tumor

100 d interleukin-10, a cytokine that suppresses cellular immunity and favors viral replication.

101 a regulatory connectome of genes related to cellular immunity and fibrosis.

102 Mtb) results in the generation of protective cellular immunity and formation of granulomatous structu

103 by envelope protein boosting, elicits broad cellular immunity and functional, envelope-specific seru

104 de that MCP-1 plays a key role in regulating cellular immunity and IFN-gamma production following pne

105 n of the same HLA alleles in vaccine-induced cellular immunity and in natural immune control is of re

106 e association with progressive impairment of cellular immunity and increasing susceptibility to oppor

107 osteopontin (OPN), an important component of cellular immunity and inflammation, showed higher expres

108 he early stage of HIV infection, humoral and cellular immunity and innate immune functions in oral mu

109 ghts relationships between humoral immunity, cellular immunity and nonadherence.

110 of autologous transfer strategies to explore cellular immunity and potential therapeutic applications

111 (LdCen(-/-) and Ldp27(-/-)) induce a strong cellular immunity and provide protection against viscera

112 his may prove useful in monitoring patients' cellular immunity and recovery from active BKV infection

113 The recognition events that mediate adaptive cellular immunity and regulate antibody responses depend

114 M and Mycobacterium tuberculosis is based on cellular immunity and relies on the type-1 cytokine path

115 de evidence for transplacental regulation of cellular immunity and suggest that IL-10 may influence T

116 hat vaccine-induced MDSCs inhibit protective cellular immunity and suggest that preventing MDSC induc

117 boosting elicits enhanced intestinal mucosal cellular immunity and that oral or ileal vector delivery

118 animals provide a unique model for exploring cellular immunity and the control of SIV infection and f

119 a detailed characterization of SIV-specific cellular immunity and viral control in the first 6 mo fo

120 immunodominance is crucial to understanding cellular immunity and viral evasion mechanisms and will

121 an the other two strains in both humoral and cellular immunities, and their tumor growth was signific

122 orally coinciding with onset of SIV-specific cellular immunity, and elevated plasma Th1 cytokine and

123 for infectious agents boost humoral but not cellular immunity, and have poorly-understood mechanisms

124 e is characterized by inflammation, impaired cellular immunity, and immunosenescence.

125 genesis, preceding and outweighing antitumor cellular immunity, and likely contribute to disease prog

126 dy pTreg, the cross-talk between humoral and cellular immunity, and regulation of the inflammatory re

127 s suggest that the acute phase and activated cellular immunity are associated with increased cellular

128 Humoral and cellular immunity are both implicated, patients express

129 novel and dominant targets of KSHV-specific cellular immunity are identified and compared to T cells

130 supporting the notion that both humoral and cellular immunity are important for development of prote

131 munization, the roles of ICAM-1 in antiviral cellular immunity are less well understood.

132 range of autoantibodies, but the targets of cellular immunity are not well defined.

133 didate providing broad antiviral humoral and cellular immunity as a foundation for future development

134 He was the first to demonstrate cellular immunity as the immunopathological basis of per

135 lso exhibits adjuvant effects on humoral and cellular immunity as well as an enhancement of polyinosi

136 ill and vaccinated subjects retained strong cellular immunity, as indicated by high levels of mucosa

137 r of vitamin B-6 catabolism during activated cellular immunity, as predictors of mortality.

138 Here, we sought cellular immunity-based correlates of malaria protection

139 will inform the development of an effective cellular immunity-based human immunodeficiency virus vac

140 .p. infection with ORF31STOP elicited strong cellular immunity but a non-neutralizing Ab response.

141 ill have to appropriately stimulate not only cellular immunity, but also humoral immunity.

142 particle (VRP) boost, increasing humoral and cellular immunity by at least 1 order of magnitude compa

143 the evidence that triggering of TA-specific cellular immunity by TA-targeted mAb, in conjunction wit

144 macrophage death, as well as, activation of cellular immunity by the TA, causing increased T-cell ac

145 stinal nematodes is associated with impaired cellular immunity, characterized by reduced lymphocyte p

146 Cellular immunity, chiefly the CD8(+) T-cell response, p

147 could induce the durable, robust humoral and cellular immunity commonly seen in CMV seropositive subj

148 munodeficiency virus type 1 (HIV-1)-specific cellular immunity contributes to the control of HIV-1 re

149 IFN-gamma plays a central role in activating cellular immunity, controlling cell proliferation, and i

150 Vaccine-induced cellular immunity controls virus replication in simian i

151 While cellular immunity correlates with protection from clinic

152 Induction of cellular immunity could be optimized by targeted activat

153 s infection has been regarded as inferior to cellular immunity directed to the intracellular pathogen

154 rs as critical stromal factors in regulating cellular immunity during autoimmune hepatitis.

155 skin cells via the NK1R promotes humoral and cellular immunity during skin genetic immunizations.

156 The critical role of cellular immunity during tuberculosis (TB) has been exte

157 this prime-boost strategy can induce strong cellular immunity, especially in vaginal tissues, and mi

158 Because granulomas form when cellular immunity fails to clear antigenic stimuli, atte

159 contribution of FcgammaR in the induction of cellular immunity, FcgammaR single- and double-knockout

160 e show that PrfA*(G155S) enhanced functional cellular immunity following an intravenous or intramuscu

161 of innate immunity and HER2/neu humoral and cellular immunity following cryoablation with or without

162 tanding the relationship between humoral and cellular immunity following immunization with conjugate

163 to the development of protective humoral and cellular immunity following vaccination.

164 , and current efforts focus on understanding cellular immunity for targeted vaccine development.

165 hydrates while suppressing genes involved in cellular immunity (gamma interferon [IFN-gamma] and the

166 umab, PD-1-antibody, can enhance antimyeloma cellular immunity generated by pomalidomide, leading to

167 udy was initiated to evaluate the breadth of cellular immunity generated through immunization of rhes

168 Cellular immunity has an inherent high level of function

169 though the contribution of TRIM5 proteins to cellular immunity has not yet been studied, their intera

170 ibody affinity maturation, but their role in cellular immunity has remained unclear.

171 roperties of stem cells to maintain lifelong cellular immunity have been hypothesized for many years,

172 dies; however, vaccines exclusively inducing cellular immunity have not been studied to formally test

173 ected hosts despite CMV-specific humoral and cellular immunity; however, how it does so remains undef

174 oad occurrence of CD40L(+) CD8(+) T cells in cellular immunity implicates that helper functions are n

175 mechanism couples innate viral sensing with cellular immunity in a single protein and could be explo

176 Decline in cellular immunity in aging compromises protection agains

177 ly, whereas the kinetics of the SIV-specific cellular immunity in breast milk mirrored that of the bl

178 pamycin can also stimulate pathogen-specific cellular immunity in certain circumstances.

179 antigens in order to investigate defects in cellular immunity in cirrhosis.

180 Although earlier research implicated cellular immunity in dengue immunopathogenesis, a wealth

181 an elicit potentially important SIV-specific cellular immunity in foreskin.

182 blish the level of L. monocytogenes-specific cellular immunity in healthy adults, and, together with

183 Specific targets of cellular immunity in human premalignancy are largely unk

184 platform for the study of norovirus-induced cellular immunity in humans.

185 vant formulations fail to induce substantial cellular immunity in humans.

186 ut to investigate the role of humoral versus cellular immunity in rVSV vaccine-mediated protection ag

187 be a potential therapeutic target to restore cellular immunity in septic patients.

188 (MHC)-matched animals to assess the role of cellular immunity in SIVmac239Deltanef protection.

189 SNPs in cytokine/cytokine receptor genes and cellular immunity in subjects following primary smallpox

190 ctive comparison of M. tuberculosis-specific cellular immunity in subjects with active tuberculosis a

191 aerosol rAd immunization to generate potent cellular immunity in the lung suggests that using differ

192 emory T cell recruitment for the efficacy of cellular immunity in the lung.

193 rets, all vaccinated ferrets showed improved cellular immunity in the lungs and peripheral blood.

194 The relative importance of humoral and cellular immunity in the prevention or clearance of hepa

195 e required for optimal T cell activation and cellular immunity in this in vivo nonlymphoid tumor mode

196 y adults with Ty21a and assessed humoral and cellular immunity in vaccinated volunteers and controls

197 e, a differential requirement for humoral vs cellular immunity in vaccine-induced protection against

198 ultiple-route DNA vaccinations induce strong cellular immunity, in addition to potent and high-avidit

199 ders have revealed that states of suppressed cellular immunity, in combination with enhanced humoral

200 IVIG has a much broader ability to regulate cellular immunity including innate and adaptive componen

201 Lenalidomide significantly upregulates cellular immunity, including NK and LAK activity.

202 nical testing of vaccines designed to induce cellular immunity, including those against influenza vir

203 infectious challenge, research in pursuit of cellular immunity-inducing vaccine adjuvants should no l

204 ay was conducted to further confirm a robust cellular immunity invoked by STn-PS A1.

205 of CMV infection is largely accounted for by cellular immunity, involving various T-cell and B-cell s

206 ost of varicella zoster virus (VZV)-specific cellular immunity is a likely mechanism of action.

207 Our results demonstrate that cellular immunity is crucial to mediate cross-protection

208 cells (DC) to mediate CD4(+) T cell help for cellular immunity is guided by instructive signals recei

209 Adaptive cellular immunity is initiated by antigen-specific inter

210 In order to determine whether cellular immunity is involved in this vaccine-mediated p

211 variability and extent of cetuximab-mediated cellular immunity is not fully understood.

212 Cellular immunity is pivotal in HIV-1 pathogenesis but i

213 We aimed to define whether ADH-specific cellular immunity is present in alcoholic hepatitis.

214 ngle adjuvant that enhances both humoral and cellular immunity is rare and thus underlines the import

215 ong-standing notion that humoral rather than cellular immunity is sufficient to facilitate Lyme disea

216 Innate cellular immunity is the immediate host response against

217 form of TA from ovarian tumor that activates cellular immunity is unknown.

218 Passive cellular immunity is well accepted and has been demonstr

219 adjuvant for enhancing antiviral humoral and cellular immunity, leading to enhanced protection agains

220 lar immune responses in eukaryotes, and this cellular immunity likely involves changes in subcellular

221 tion induced both HA-specific antibodies and cellular immunity likely to provide heterotypic immunity

222 xperiment to determine whether crossreactive cellular immunity limits symptomatic illness in antibody

223 lar rAd5-Env boosting increased Env-specific cellular immunity markedly in mucosal as well as systemi

224 tective immunity, and there is evidence that cellular immunity may also be important in related arena

225 d suggest that crosstalk between the CNS and cellular immunity may be a general mechanism by which in

226 A vaccine that induces both humoral and cellular immunity may be required to prevent congenital

227 Given evidence suggesting that cellular immunity may play a role in viral suppression,

228 agglutination-inhibiting (HI) antibodies and cellular immunity measured by ex vivo leukocyte response

229 S) serotype-specific capsular polysaccharide cellular immunity, measured with enzyme-linked immunospo

230 CMV-specific cellular immunity might directly contribute to this proc

231 gens; however, the impact of vector-specific cellular immunity on subsequent insert-specific T cell r

232 -gamma, TNF-alpha, and NOS2, key elements of cellular immunity, perform critical protective functions

233 Because cellular immunity plays a key role in the control of the

234 of neutralizing antibodies, indicating that cellular immunity plays a primary role in viral clearanc

235 Finally, pretransplant assays of anti-CMV cellular immunity predicted post-transplant CMV replicat

236 sponses in the lungs explains why protective cellular immunity quickly declines following influenza v

237 ose of the control monkeys while MV-directed cellular immunity reached levels at least as high as in

238 Evidence of long-lasting cellular immunity, regardless of anti-HBs level, suggest

239 ancer, but the direct effect of androgens on cellular immunity remains largely uncharacterized.

240 pectives for differential shaping of desired cellular immunity required to fight the wide range of co

241 Adaptive cellular immunity requires accurate self- vs. nonself-di

242 , the preferential activation of humoral and cellular immunity, respectively.

243 to selection pressures from both humoral and cellular immunity, resulting in the continuous generatio

244 nation strategies designed to elicit durable cellular immunity should target the generation of TSCM c

245 This coordinated "double hit" to cellular immunity strongly implicates the role of exosom

246 ast Asia, especially for those with impaired cellular immunity such as human immunodeficiency virus-i

247 h emphasis on the tumor microenvironment and cellular immunity, taking into account novel nanotechnol

248 r induction of virus-specific antibodies and cellular immunity than would gD2t.

249 ork of Elie Metchnikoff and the discovery of cellular immunity, the phagocytic clearance of cellular

250 ral protection against pathogens and promote cellular immunity through diverse nonclassical effector

251 tibodies have important roles in controlling cellular immunity through interaction with activating or

252 Enhancement of cellular immunity through T-cell and NK-cell activation

253 Instead, IFITM3 promoted antiviral cellular immunity through the restriction of virus-induc

254 virus (EBV) provides a useful model to study cellular immunity to a genetically stable, persistent hu

255 Although cellular immunity to acute lymphocytic choriomeningitis

256 CD154 mediates key facets of humoral and cellular immunity to alloantigens, and is tolerogenic to

257 is overlapping, and preexisting humoral and cellular immunity to both are exhibited in human populat

258 cPLA(2) in the induction of cell autonomous cellular immunity to Chlamydia and highlight the many no

259 s a major barrier limiting the capability of cellular immunity to contain infection and the ability o

260 This study investigates the contribution of cellular immunity to cross-protection using mouse models

261 Further, expecting cellular immunity to enhance chronic viremia control, we

262 may be required toward mechanisms that boost cellular immunity to gH and gL within future subunit vac

263 ntigen (HBsAg) sometimes develop humoral and cellular immunity to HBV proteins such as core and polym

264 the effects of TIV and LAIV immunization on cellular immunity to live influenza A virus in children

265 The persistence of cellular immunity to mumps vaccine has not been defined.

266 difference in the development of humoral or cellular immunity to pneumococcal colonization between w

267 l much to learn about natural resistance and cellular immunity to pneumococcus.

268 vaccines should elicit effective humoral and cellular immunity to protect an individual from infectio

269 r data suggest that eosinophils promote host cellular immunity to reduce influenza virus replication

270 are thought to have a function in intrinsic cellular immunity to several viruses including human imm

271 Cellular immunity to SOX2 inhibits the clonogenic growth

272 Animals immunized with rat MAA developed cellular immunity to the antigen.

273 e products often mediate opposing effects on cellular immunity to tumor cells, pathogens, and autoant

274 sed adjuvant effects in boosting humoral and cellular immunity to vaccinia virus.

275 inants of the AAVrh32.33 capsid that augment cellular immunity to vector-encoded proteins or those of

276 esults indicate that after infection durable cellular immunity to WHV is essential for the long-term

277 s and altered long-term persistence of human cellular immunity to YF vaccination.

278 bination antiretroviral therapy, recovery of cellular immunity triggers inflammation to a preexisting

279 cus on humoral immunity, leaving the role of cellular immunity unclear.

280 a key autoantigen driving the Th17-dependent cellular immunity underlying another chronic inflammator

281 However, the ability to induce protective cellular immunity varies among rAds.

282 The ability to induce humoral and cellular immunity via antigen delivery through the unbro

283 rP18tri vector can induce strong humoral and cellular immunity via different immunization routes and

284 dherence to host cells, and modulating human cellular immunity via interactions with T cells and neut

285 rotection was mainly antibody dependent, but cellular immunity was also beneficial in protecting agai

286 Donor-specific HLA class II cellular immunity was analyzed using enzyme-linked immun

287 Adaptive antiviral cellular immunity was increased in mCMV-infected VIP-KO

288 elation between SIV viremia and SIV-specific cellular immunity was not detected.

289 Cellular immunity was reduced in parallel with depleted

290 ical anergy and other evidence of diminished cellular immunity, we hypothesized that decreased skin d

291 mechanisms underlying wasp virulence and fly cellular immunity, we used a joint transcriptomic/proteo

292 protection for DENV vaccines on the basis of cellular immunity, we wanted to compare the cellular imm

293 s in overcoming age-associated deficiency in cellular immunity were investigated.

294 Also, few adjuvants induce strong cellular immunity, which is important for protection aga

295 ate a multifaceted immune response including cellular immunity, which may provide protection against

296 Aging leads to reduced cellular immunity with consequent increased rates of inf

297 ntibodies and Th1-predominant donor-specific cellular immunity with high frequency of IFN-gamma and l

298 1 vaccine is devising a strategy to generate cellular immunity with sufficient breadth to deal with t

299 of the CD40-CD154 immune pathway in boosting cellular immunity within epithelia.

300 an emerging technology to induce therapeutic cellular immunity without the need for autologous antige