ライフサイエンスコーパス: cellular response

1 ing and signaling for the fine-tuning of the cellular response.

2 dinucleotide that initiates an inflammatory cellular response.

3 s of proteins acting in concert to shape the cellular response.

4 ignaling pathways resulting in a pleiotropic cellular response.

5 pendent gene regulation in a photoprotective cellular response.

6 cell membrane and simultaneously measure the cellular response.

7 lic dsRNA, and activation of an IFN-inducing cellular response.

8 biology of premalignancy and the surrounding cellular response.

9 ect of hormonal signaling or a difference in cellular response.

10 l for translating extracellular stimuli into cellular responses.

11 ules that convert environmental stimuli into cellular responses.

12 regulate a wide range of target proteins and cellular responses.

13 actors (HIFs) are central mediators of these cellular responses.

14 might be a critical element in establishing cellular responses.

15 plify weak, rare and local stimuli to induce cellular responses.

16 cular human embryonic carcinoma and examined cellular responses.

17 determine its role in controlling polarized cellular responses.

18 egulation and integration of IQGAP1-mediated cellular responses.

19 l initiation and integration for appropriate cellular responses.

20 erring IL-21 with a role in both humoral and cellular responses.

21 a proteins integrates downstream signals and cellular responses.

22 for considering how kindlins might regulate cellular responses.

23 system are master regulators of an array of cellular responses.

24 E4-like SUMO elongase to impact a variety of cellular responses.

25 chanisms by which inflammation impacts local cellular responses.

26 iptional networks to elicit a diverse set of cellular responses.

27 ng with cisplatin derivatives and associated cellular responses.

28 ul coordination between these interdependent cellular responses.

29 icitation of protective innate, humoral, and cellular responses.

30 aterial interactions and to find patterns in cellular responses.

31 d can induce or modulate a broad spectrum of cellular responses.

32 etween IP3Rs and the selective regulation of cellular responses.

33 r a thousand LINCS cell line cells and their cellular responses.

34 lent activity in blocking many TNF-dependent cellular responses.

35 Ligands can elicit full or subsets of cellular responses, a concept defined as ligand bias or

36 e used a linear decoder to determine whether cellular responses across each of the cortical and limbi

37 vidence that new genetic features regulating cellular response after DNA damage can be identified.

38 ox1(+/+) and Hmox1(-/-) animals and analyzed cellular response after muscle injury, focusing on muscl

39 Altogether, we conclude that FASN regulates cellular response against genotoxic insults by up-regula

40 he regulation of pivotal pathways related to cellular response and stability.

41 Pathogen invasion triggers a number of cellular responses and alters the host transcriptome.

42 ) kinase signaling cascades trigger specific cellular responses and are involved in multiple disease

43 2+) concentrations (80-120 muM) had opposite cellular responses and behaviors.

44 are highly attractive for eliciting desired cellular responses and for understanding biological proc

45 riety of stress stimuli and is implicated in cellular responses and gene regulation.

46 l pathogens, osmotic stress sensitivity, and cellular responses and total ion accumulation in the pla

47 surements, and O2 monitoring-to the study of cellular responses and use in rodent models.

48 accine candidate provided robust humoral and cellular responses, and afforded 100% protection against

49 sing and transduction of stress signals into cellular responses, and the mechanistic interfaces betwe

50 shes between (1) cytotoxic versus cytostatic cellular responses; and (2) changes in morphological fea

51 gic mechanical signals are transduced into a cellular response are not well understood.

52 Adaptive cellular responses are often required during wound repai

53 d, moreover, it is thought that PCP mediated cellular responses are tissue-specific.

54 are well described in peripheral blood, the cellular response at the intestinal mucosa has never bee

55 Fluctuating currents resulted in strong cellular responses at stimulation frequencies beyond the

56 wide transcriptional analysis to investigate cellular responses at these sublethal concentrations.

57 l zebrafish with the goal of identifying the cellular responses, brain regions, and brain-wide pathwa

58 Human regulatory B (Breg) cells modulate cellular responses, but their control of TFH cell-depend

59 In addition, these factors also control the cellular response by directing signaling toward G-protei

60 pro-resolving lipid mediators that regulate cellular response by orchestrating resolution networks i

61 Classically, hormones elicit specific cellular responses by activating dedicated receptors.

62 growth factor-betas regulate a wide range of cellular responses by activating Smad-dependent and Smad

63 These findings suggest that complex cellular responses can be effectively described using a

64 d epigenetic changes) results in a number of cellular responses (cellular senescence, deregulated nut

65 Senescence is a cellular response characterized by a stable growth arres

66 density of actin, which yields to a tunable cellular response, characterizes these dynamic structure

67 vides statistical descriptions of multiscale cellular response consistent with many datasets.

68 he presence of nicotine in e-vapor elicits a cellular response distinct from e-vapor alone including

69 significant homology, they regulate distinct cellular responses downstream of these receptors and pla

70 T as a downstream effector of the PDGFRalpha cellular response during CIL.

71 rphogenetic proteins (BMPs) regulate diverse cellular responses during embryogenesis and in adulthood

72 genomics revealed an alteration in viral and cellular responses during hyperfusion that was caused by

73 d out an unbiased analysis of the integrated cellular response elicited by two chemically and pharmac

74 for this reprogramming and for the sustained cellular responses elicited by LO, both in vitro and in

75 stimulus is simulated, predicting a reduced cellular response for cells that were first exposed to a

76 pending on their geometries, elicit distinct cellular responses for the same cytokine.

77 is resistance to p53 activation by switching cellular response from G1 arrest to apoptosis.

78 d initiation of interactions enables probing cellular responses from the very onset, permitting singl

79 dence linking their mechanical stability and cellular response has been lacking.

80 Harnessing humoral and innate cellular responses has become one focus of research to d

81 conjunction with clinical response are also cellular response hubs.

82 reds of genes to induce a robust anti-stress cellular response in fission yeast.

83 unction between the stimulus and the overall cellular response in the Laplace-transformed domain.

84 Induction of a type 2 cellular response in the white adipose tissue leads to w

85 e of AIT-induced blocking Ab separately from cellular responses in a chimeric human/mouse model of re

86 peutic modality for inactivating antioxidant cellular responses in a wide range of malignancies.

87 Using calcium imaging of cellular responses in awake mice, we find surprising asy

88 important signaling modules for a variety of cellular responses in eukaryotic cells.

89 ic, as two doses elicited potent humoral and cellular responses in mice that exceed the threshold cor

90 ated in this molecular exchange, as cues for cellular responses in symbiotic microbes.

91 Decreased cellular responses in WASp-deficient cells have been int

92 co-limited cell lines demonstrated a complex cellular response including increased growth rates, broa

93 o STAT3 phosphorylation, suggesting multiple cellular responses including metabolic adaptation.

94 ce p53 target genes are involved in multiple cellular responses, including cell cycle arrest, DNA rep

95 abilized under low oxygen tension to mediate cellular responses, including cell fate decisions.

96 obulin E-bound FcepsilonRI triggers multiple cellular responses, including degranulation and cytokine

97 M) domain adaptor protein, mediates numerous cellular responses, including integrin activation.

98 llenge the resident genome and must overcome cellular responses, including the DDR.

99 The cellular response increased following mucosal BCG-prime-

100 at substrate rigidity induces some universal cellular responses independently of the porosity or topo

101 ere we describe a previously uncharacterized cellular response induced by heme: the formation of p62/

102 ta unravel a poorly understood aspect of the cellular responses induced by heme that can be explored

103 e sequencing (RNA-seq) to identify viral and cellular responses induced when gBcyt regulation was dis

104 The subsequent energetic crisis induced two cellular responses involving cyclin-dependent kinases (C

105 ls/hydrogel culture construct is tedious and cellular response is difficult to be quantitatively anal

106 Cellular response is initiated through a signaling prote

107 l for transducing environmental signals into cellular responses, leading to metabolic and physiologic

108 ivation may alter the biological outcomes of cellular responses markedly, here, we investigated the e

109 sing chick embryos, we show that the hypoxic cellular response, mediated by hypoxia-inducible factor

110 f multiple genes, including wg, and restores cellular responses necessary for regeneration.

111 w ARF6 coordinates the activation of complex cellular responses needs to be further elucidated.

112 We investigate the cellular response of the bloom-forming coccolithophore E

113 show that pharmacological suppression of the cellular response of the innate immune system inhibits m

114 image processing algorithms to simulate the cellular response of tumours exposed to ionizing radiati

115 Cellular responses of Brachypodium were investigated thr

116 to the roles of circulatory shear stress in cellular responses of circulating tumor cells in a physi

117 ed this question by comparing behavioral and cellular responses of mice with the selective ablation o

118 We analyzed these cellular responses on fibronectin-coated polyacrylamide

119 ve a broad role in gene induction in diverse cellular responses, particularly throughout the immune s

120 lucidate how gradient characteristics govern cellular response patterns, we here introduce an in vitr

121 erogeneity in virulence factor injection and cellular responses play an important role in promoting a

122 of transcript abundance, protein levels, and cellular response profiles from matched, serial biospeci

123 ed receptors (GqPCRs) might induce divergent cellular responses, related to receptor-specific activat

124 genes encoding metabolites that elicit host cellular responses represents a possible small-molecule

125 CAN channels are involved in cellular responses such as neuronal bursting activity an

126 physiological signaling during extraordinary cellular responses, such as injury and wound healing, an

127 inefficient induction (58% response rate) of cellular responses targeting these CE.

128 al calcium uptake may constitute an adaptive cellular response that confers a survival advantage in r

129 thways may benefit from increased study into cellular responses that arise from long-term or ectopic

130 reover, DAMPs may incite distinct downstream cellular responses that could specifically contribute to

131 the specific matrix signals and the induced cellular responses that drive the fibrogenic phenotype r

132 s of this assembly machinery trigger complex cellular responses that prevent aggregation of unassembl

133 roenvironmental changes instruct a series of cellular responses that trigger cardiac fibroblasts-medi

134 r stimuli into the appropriate intracellular cellular response, they must use the 10 ITAMs found with

135 e receptors (S1P1-5) and evokes a variety of cellular responses through their stimulation.

136 The cellular response to 27OHC was hormetic, such that low,

137 Our results offer a direct visualization of cellular response to a noncanonical acrolein warhead.

138 RAGE binds and mediates the cellular response to a range of damage-associated molecu

139 es transportation of signaling molecules and cellular response to aid the design of future living mat

140 Lysosomes play key roles in the cellular response to amino acid availability.

141 P1 regulation playing a critical role in the cellular response to apoptotic pathway activation in the

142 This is a new previously unknown cellular response to CAP, which provides a new prospecti

143 trocytes represents an important maladaptive cellular response to cocaine and the mechanisms underlyi

144 Nilotinib treatment and LDR, to explain the cellular response to combination therapy.

145 itanium physicochemistry and thus compromise cellular response to decontaminated surfaces.

146 hat play key roles in sensing and regulating cellular response to diverse external signals.

147 l HPV-host interaction that functions in the cellular response to DNA damage and cell cycle control.

148 utated (ATM)- and Rad-3-related (ATR) in the cellular response to DNA damage during the replicative p

149 The eukaryotic cellular response to DNA damage is orchestrated by the D

150 uncovered a relationship between AXL and the cellular response to DNA damage whereby abrogation of AX

151 ICA, MICB and ULBP 1-6 are up-regulated as a cellular response to DNA damage, excessive proliferation

152 lts in attenuated p21 induction and impaired cellular response to DNA damage.

153 ew insights into the genetic basis of tumour cellular response to DNA damage.

154 and uncover a unique function of SOX9 in the cellular response to DNA damage.

155 ation of proteins plays pivotal roles in the cellular response to DNA damage.

156 The cellular response to DNA double-strand breaks (DSBs) is

157 cooperative modification with Ub, using the cellular response to DNA DSBs as the primary setting to

158 ation-deficient SLX4 mutants cause defective cellular response to DNA interstrand crosslinking agent

159 wed that this assay can detect heterogeneous cellular response to drug treatment and that the sum of

160 een the expression of key proteins and their cellular response to drug treatment.

161 egulates CtIP-mediated DNA end resection and cellular response to DSBs.

162 dels) at the target locus resulting from the cellular response to dsDNA breaks.

163 Using FISH, Xu et al. here analyze the cellular response to DVGs on a single cell level and sho

164 dicates a role of FOXC1 in the modulation of cellular response to endocrine treatment.

165 to as BiP or HSPA5) is part of the adaptive cellular response to endoplasmic reticulum (ER) stress.

166 erial two-component systems that mediate the cellular response to environmental changes.

167 Loss of LKB1 expression altered the cellular response to erlotinib treatment, resulting in i

168 of cycling, resting, and exiting shapes the cellular response to extrinsic stimuli, whereas prevalen

169 eatic cancer cell proliferation and enhanced cellular response to gemcitabine in a FKBP51-AKT-depende

170 s, suggesting that autophagy is a protective cellular response to gemcitabine treatment.

171 first time, the involvement of ZNF281 in the cellular response to genotoxic stress through the contro

172 nduced NOX2 activation, ruling it out in the cellular response to HG.

173 hreonine protein kinase known to inhibit the cellular response to hypoxia and tumorigenesis.

174 The cellular response to hypoxia is characterised by a switc

175 The cellular response to hypoxia is critical for cell surviv

176 Elevated cellular response to hypoxia, which contributes to cell

177 l processes, including cell differentiation, cellular response to hypoxic stress, and carcinogenesis.

178 rmerly unrecognized but integral part of the cellular response to impaired proteasome function and al

179 results demonstrate the diversity of tumour cellular response to ionizing radiation and establish mu

180 to gain insight into its function during the cellular response to LPS stimulation.

181 fic differentiation of hESCs by altering the cellular response to morphogens.

182 are central signal transducers mediating the cellular response to multiple stimuli in most eukaryotes

183 death may provide a detailed readout of the cellular response to novel therapies and prognostic info

184 e that women with PMDD might differ in their cellular response to ovarian steroids.

185 Because cellular response to oxidative challenge is accompanied

186 he transcription factor Foxo3 integrates the cellular response to oxidative stress and plays a role i

187 er genes.APE1 plays an important role in the cellular response to oxidative stress, and mutations are

188 ey transcription factor and regulator of the cellular response to oxidative stress.

189 alcium signalling, complement activation and cellular response to oxidative stress.

190 stigate whether there are any differences in cellular response to PARPi olaparib depending on the BRC

191 own about the role of the RNA exosome in the cellular response to pathogens.

192 this paper we present a mechanistic model of cellular response to radiation that incorporates the kin

193 and not by replication stress or a defect in cellular response to replication stress.

194 among several other proteins involved in the cellular response to replicative stress significantly ab

195 regulators and pathways that orchestrate the cellular response to ssUVR.

196 role in tissue homeostasis and regulate the cellular response to stress and inflammation, highlighti

197 Activated TFEB and TFE3 enhance cellular response to stress by inducing direct transcrip

198 and are critically involved in regulation of cellular response to stress conditions.

199 se data identify new mechanisms by which the cellular response to stress is differentially controlled

200 ences a broader role of TFEB and TFE3 in the cellular response to stress than previously anticipated

201 mitochondrial fission and, consequently, the cellular response to stress.

202 3 activity as a transcriptional regulator of cellular response to stress.

203 ceptibility to DNA damage, and influence the cellular response to such damage, caused by an environme

204 t not of D2S, strongly impairs the motor and cellular response to the drug, in a manner similar to th

205 a suggest the importance of p19(Arf) for the cellular response to the low-level DNA damage incurred i

206 se RNAs are also components of an integrated cellular response to the metabolic milieu.

207 r Mg(2+)-dependent enzymes then constitute a cellular response to the perturbation.

208 Investigations are underway to determine the cellular response to this interaction to understand how

209 ation-dependent mechanism that regulates the cellular response to TNF and may promote cancer cell sur

210 ogical functions, regardless of cell type or cellular response to TP53 activation.

211 uncover a new role for NONO in mediating the cellular response to UV-induced DNA damage.

212 ly, targets several pathways involved in the cellular response to viral infection.

213 ing hydrogel formation and then analyzed for cellular responses to 3D hypoxic gradients and to elucid

214 landscape that correlated with differential cellular responses to a panel of signaling and epigeneti

215 By measuring cellular responses to a spectrum of spatial, chemical, t

216 n provide efficient, dynamic, and reversible cellular responses to a wide range of environmental stim

217 Additionally, AIT modulates cellular responses to allergens, for example, by desensi

218 g pheromone pathway, which in turn abolishes cellular responses to alpha factor; and iv) blocks cell

219 nt growth kinetics and enables assessment of cellular responses to antibiotics and antimicrobial pept

220 s such as the Shh signal can pattern distant cellular responses to assure functional integrity during

221 econdary messenger involved in a plethora of cellular responses to biological agents involving activa

222 Overall cellular responses to biologically-relevant stimuli are

223 CN is the key mediator of cellular responses to Ca(2+) signals and its deregulatio

224 Several cellular responses to CAP treatment have been observed i

225 alcium-sensing receptor, CaSR, which enables cellular responses to changes in extracellular calcium,

226 entrations would expand the dynamic range of cellular responses to changes in ppGpp levels.

227 myelination and NMII has been implicated in cellular responses to changes in the elasticity of the E

228 ignals into regulatory pathways that control cellular responses to changing conditions.

229 ic factor that is mechanistically coupled to cellular responses to chloride stress.

230 e therefore examined the role of p19(Arf) in cellular responses to chronic, low-dose DNA-damaging age

231 aled that in vitro SLC16A5-silencing altered cellular responses to cisplatin treatment, supporting a

232 is concomitant with the local modulation of cellular responses to cytokinin and auxin, two key phyto

233 Aiming to understand cellular responses to different perturbations, the NIH C

234 hancers dictate distinct cell identities and cellular responses to diverse signals by instructing pre

235 ience, the effect of glutamine deficiency on cellular responses to DNA damage and chemotherapeutic tr

236 itin recognition and metabolism and promotes cellular responses to DNA damage.

237 Chromatin relaxation is one of the earliest cellular responses to DNA damage.

238 d transcription is an important mediator for cellular responses to DNA damage.

239 ribose) polymerase 1 (PARP1), is crucial for cellular responses to DNA damage.

240 BAG-1 can modulate cellular responses to E2 by regulating the establishment

241 imary cells without affecting other hallmark cellular responses to ECM stiffening including cell spre

242 scTDA can be applied to study asynchronous cellular responses to either developmental cues or envir

243 signed to selectively target RNAs and affect cellular responses to environmental conditions, resultin

244 of plant cells, and the extent of localized cellular responses to environmental inputs.

245 revealed that strain SN2 displayed specific cellular responses to environmental variables (tidal fla

246 e erythropoietin receptor (EPOR) mediate the cellular responses to erythropoietin (EPO) in different

247 Chemical modifications of RNA allow rapid cellular responses to external stimuli by modulating a w

248 tosis provide a critical level of control of cellular responses to guidance signals.

249 This study investigated the viral and cellular responses to hyperfusion, a condition where the

250 pression on macrophages, which rescued their cellular responses to IFN-gamma.

251 Temporal proteomics analysis of cellular responses to infection showed that the avian vi

252 RT inflammatory cytokine surge, likely limit cellular responses to infection.

253 odegenerative pathways share several altered cellular responses to insults such as oxidative stress,

254 s mir-200 expression is one of the important cellular responses to KRAS activation during tumor initi

255 1 and A2A receptors, play major roles in the cellular responses to l-DOPA in the striatum, these find

256 ach, providing a framework for prediction of cellular responses to new cytokine combinations and dose

257 of the expression of many genes involved in cellular responses to oxidative and other stresses.

258 nd serves as a central regulator of adaptive cellular responses to oxidative stress.

259 conditioning with phenolic sulfates improved cellular responses to oxidative, excitotoxicity and infl

260 penetrant phenotypes, but rather, influences cellular responses to physiologic and pathophysiologic s

261 NbGlk1 activates cellular responses to potato virus X, whereas Rx1 associ

262 interstrand crosslinks (ICLs) and regulates cellular responses to replication stress.

263 Down-regulation of PKM2 by shRNA blunts cellular responses to shikonin but enhances the response

264 Our data reveal a mechanism by which cellular responses to stalled replication forks can acti

265 Cellular responses to stimuli are rapid and continuous a

266 resting cells, leaving their role in dynamic cellular responses to stimuli largely unexplored.

267 ctions are known to be a useful parameter in cellular responses to stress.

268 ld anisotropy also made it possible to probe cellular responses to stretch as a function of fiber ang

269 roles of these signals are well studied, the cellular responses to the combined chemical and physical

270 Model-predicted cellular responses to the combined therapy provide good

271 We examined a role for immunoproteasomes in cellular responses to the endogenous and environmental c

272 sted ribosomal proteins, indicating distinct cellular responses to the inhibition of different steps

273 They also presented a lower frequency of cellular responses to the parasite (DTH).

274 s architecture or accurately predict in vivo cellular responses to therapeutics.

275 erwarfarins to biomembranes and suggest that cellular responses to these agents are regulated by chol

276 ticulate materials in human airways, shaping cellular responses to these materials, and improving our

277 tifunctional DNA repair factor that controls cellular responses to TOP2 damage.

278 In this article, we review the cellular responses to transcription-replication conflict

279 Cellular responses to type I IFN signaling are orchestra

280 ic skin may be caused by defects in multiple cellular responses to UVB-induced DNA damage, including

281 regulation of specific pathways involved in cellular responses to viral infection and cell survival.

282 and on IRF1, a transcriptional regulator of cellular responses to viral invasion and DNA damage.

283 Type I IFNs promote cellular responses to viruses, and IFN receptor (IFNAR)

284 e tight control of both biosynthesis of, and cellular responses to, PGE2 are critical for the precise

285 n of cortical myosin dynamics is part of the cellular response triggered by a "chromatid separation c

286 ncing, we performed a genomewide analysis of cellular responses triggered by VLVs and found that PRDM

287 The cellular response under this pathological retinal condit

288 ate environmental sensing with initiation of cellular responses underpins microbial survival and is c

289 -based NP formulations to re-program in vivo cellular responses using nanotechnology.

290 uction profiles and enables determination of cellular response variability to electron transfer chain

291 Cellular response was determined by measuring intracellu

292 The cellular response was more pronounced at higher frequenc

293 Shear stress-induced molecular and cellular responses were defined and verified using vario

294 These cellular responses were investigated further using flow-

295 Viral replication and cellular responses were measured using quantitative real

296 Cellular responses were monitored with postexposure incu

297 Cellular responses were observed in 57% of vaccine recip

298 However, similar data are lacking for the cellular response, which in gnathostomes is regulated by

299 tive provides a simplified representation of cellular response while reducing the dimensions in gene-

300 sKlotho elicits pleiotropic cellular responses with a poorly understood mechanism of