1 nt of a perfectly unique cell type remains a
central question.
2 ype productively infected by MCPyV remains a
central question.
3 ens involved in triggering this process is a
central question.
4 nization regulates gene expression remains a
central question.
5 eneficial and evolutionarily successful is a
central question.
6 new millennium poised to answer many of its
central questions.
7 te NMR spectroscopy is used to address these
central questions.
8 research in experimental philosophy on four
central questions.
9 principles, which collectively address four
central questions: (
a) What is a relationship?
10 Presently, the
central question about caspase-6 structure and function
11 A
central question about human brain aging is whether cogn
12 A
central question about the brain is how information is p
13 A
central question about the role of Abeta in disease conc
14 A
central question about the role of alphaS in the pathoge
15 A
central question about the Wnt pathway is the regulation
16 To address this
central question and to define the molecular and cellula
17 The origin of species remains a
central question,
and recent research focuses on the rol
18 Central questions are to determine which cells among pro
19 A
central question arising from these observations is whet
20 ggregates populate the meninges, raising the
central question as to whether these structures relate t
21 The
central questions asked in whole-genome association stud
22 best represented as dimensions or spectra, a
central question becomes how to implement dimensional di
23 ingle target grammar and one PLD source, the
central question being whether the target grammar can be
24 A
central question concerns the mechanism of microfibril s
25 A
central question concerns the morphology of the last com
26 ices are available for a given amino acid, a
central question concerns whether viral sequences have e
27 One
central question critical to device performance is how t
28 sh in this harsh environment by addressing a
central question:
did exposure to hypoxia drive adaptati
29 plasticity mechanisms in the brain raises a
central question:
does a neural circuit store all memori
30 One
central question for ACHRE was to determine what role, i
31 specific transcriptional programs remains a
central question for all eukaryotes.
32 A
central question for all LacI family proteins concerns t
33 on from multiple upstream regions has been a
central question for decades.
34 these different responses are regulated is a
central question for developmental biology.
35 Formation of the fusion pore is a
central question for regulated exocytosis by which secre
36 ous assembly of microscale compartments is a
central question for the origin of life, and has technol
37 The present work investigates this
central question for the prototype Ir(1,5-COD)Cl/gamma-A
38 Therefore, a
central question for the structural biology of IFs is wh
39 A
central question for the theory is to determine conditio
40 positioning of the centrosome are unknown, a
central question given the role of cilia in fluid propul
41 ddition to the scientific issues at stake, a
central question has been how scientists can maintain th
42 g examples of current studies that address a
central question:
How do neural stem cells (NSCs) divide
43 rchers led by John Gurdon interrogated three
central questions:
how are cell type-specific programs g
44 A
central question important to understanding DNA repair i
45 A
central question in Alzheimer's disease (AD) is the role
46 A
central question in Alzheimer's Disease (AD) is whether
47 A
central question in Alzheimer's disease (AD) research is
48 A
central question in Alzheimer's disease concerns the mec
49 A
central question in Alzheimer's disease research is what
50 A
central question in animal evolution is how multicellula
51 A
central question in biology is how genes control the exp
52 A
central question in biology is how spatial information i
53 Although it is a
central question in biology, how cell shape controls int
54 es the stabilization of such assemblies is a
central question in biology.
55 A
central question in both diseases is how the loss of cel
56 A
central question in cancer biology is whether malignancy
57 A
central question in cancer biology is why most tumor sus
58 with approximate phenotypic equivalency is a
central question in cancer biology.
59 petence to colonize distant organs remains a
central question in cancer biology.
60 A
central question in cancer immunology is whether recogni
61 A
central question in cancer therapy is how individual cel
62 A
central question in cell biology is how cells determine
63 A
central question in cell biology is how the identity of
64 igenetic marks and gene regulation remains a
central question in chromatin biology.
65 A
central question in cognitive neuroscience concerns the
66 A
central question in cognitive neuroscience is whether me
67 A
central question in cognitive neuroscience regards the m
68 A
central question in community ecology is the means by wh
69 egulatory landscape of the human genome is a
central question in complex trait genetics.
70 A
central question in development is to define how the equ
71 basis of morphological complexity remains a
central question in developmental and evolutionary biolo
72 nance and differentiation of stem cells is a
central question in developmental biology.
73 enetic divergence and genetic structure is a
central question in ecology and evolution.
74 A
central question in ecology with great importance for ma
75 sms that determine biological diversity is a
central question in ecology.
76 s by which new protein functions evolve is a
central question in evolutionary biology, biochemistry,
77 The emergence of cooperation is a
central question in evolutionary biology.
78 The evolutionary cost of gene loss is a
central question in genetics and has been investigated i
79 A
central question in glioblastoma multiforme (GBM) resear
80 A
central question in gustatory research is how informatio
81 A
central question in Hedgehog (Hh) signaling is how evolu
82 A
central question in hematopoiesis is how cell-cycling be
83 A
central question in histone code theory is how various c
84 Therefore, a
central question in immunology is how the naive T cell p
85 A
central question in immunology is the origin of long-liv
86 A
central question in insect chemoreception is whether sig
87 A
central question in iron-based superconductivity is the
88 etabolic cues from the environment remains a
central question in kidney research.
89 A
central question in lignin biosynthesis is how guaiacyl
90 ne repression to gene activation represent a
central question in mammalian development.
91 n gene activation and repression events is a
central question in mammalian organogenesis, as exemplif
92 to emergence of specific cell types remain a
central question in mammalian organogenesis.
93 he mechanism of Bax/Bak activation remains a
central question in mitochondria-dependent apoptotic sig
94 For over 30 years a
central question in molecular evolution has been whether
95 otein and regulatory sequence evolution is a
central question in molecular evolution.
96 d mode of protein evolution continue to be a
central question in molecular evolution.
97 sive stage occurs and how to prevent it is a
central question in MS.
98 A
central question in muscle biology is how costameres are
99 A
central question in myelin biology is the extent to whic
100 r state in metal nanoparticles constitutes a
central question in nanoscience research because of its
101 nanoparticles with increasing size remains a
central question in nanoscience.
102 preaders that maximize information flow is a
central question in network theory.
103 A
central question in neural development is how the broad
104 rons make specific synaptic connections is a
central question in neurobiology.
105 r the long distance to the channel remains a
central question in neurobiology.
106 A
central question in neuroscience is how interactions bet
107 A
central question in neuroscience is to understand how no
108 asites with wide host ranges can evolve is a
central question in parasite evolution.
109 tem cell perpetuation and organogenesis is a
central question in plant biology.
110 cytokinesis in the embryo and endosperm is a
central question in plant reproductive biology.
111 A
central question in population ecology is the role of 'e
112 A
central question in protein evolution is the extent to w
113 A
central question in protein-DNA recognition is the origi
114 A
central question in reverse engineering of genetic netwo
115 producible patterns with high precision is a
central question in science.
116 ated by their microenvironment or niche is a
central question in stem cell and regenerative biology.
117 A
central question in stem cell biology is whether organ h
118 nd differentiation of neural stem cells is a
central question in stem cell biology.
119 A
central question in stem cell research is how stem cells
120 s the organization of the transcriptome is a
central question in systems genetics.
121 A
central question in telomerase function is how transloca
122 A
central question in the area of signal transduction is w
123 A
central question in the field concerns the relationship
124 A
central question in the field is to understand how diffe
125 nd integrated with pre-existing tissues is a
central question in the field of regeneration.
126 orce gates mechanotransduction channels is a
central question in the field, for which there are two m
127 via the PDF receptor (PDFR) occurs is now a
central question in the field.
128 A
central question in the study of cell proliferation is,
129 A
central question in the study of vapour-deposited glasse
130 cause requirements for HAT complexes vary, a
central question in transcriptional regulation is how di
131 A
central question in understanding the mechanism of integ
132 A
central question in urban ecology is why some species ad
133 A
central question in vascular biology is the role of the
134 A
central question in visual neuroscience is what circuits
135 A
central question in Wnt signaling is the regulation of b
136 e scales for regulation of this response are
central questions in biochemistry.
137 e over the course of disease and therapy are
central questions in cancer biology.
138 The
central questions in common AD focus on whether cerebral
139 ific cells are selected to die is one of the
central questions in development.
140 One of the
central questions in developmental biology is that of ho
141 nism of protein sequence evolution have been
central questions in evolutionary biology since the 1960
142 such regions form and how they evolve remain
central questions in evolutionary genetics.
143 superconducting gap above T(c) is one of the
central questions in high-T(c) research.
144 One of the
central questions in neurobiology is how experience modi
145 One of the
central questions in neuroscience is how particular task
146 interventions, or genetic manipulations are
central questions in neuroscience.
147 lates of learning has constituted one of the
central questions in neuroscience.
148 selectivity during extinction events remain
central questions in palaeobiology.
149 logical selectivity at extinction events are
central questions in palaeobiology.
150 s and the nature of taxonomic radiations are
central questions in paleobiology.
151 Differences in gene expression underlie
central questions in plant biology extending from gene f
152 ore, and use this information to investigate
central questions in prion biology.
153 Two
central questions in signaling are the mechanism of acti
154 ir proliferation and differentiation are two
central questions in stem cell biology.
155 One of the
central questions in the biophysics of the mammalian coc
156 how these may affect population dynamics are
central questions in the field of animal migration [1] t
157 One of the
central questions in the field of Ras biology is how the
158 easure of insect cold tolerance used to test
central questions in thermal biology and predict the eff
159 A
central question is how EGFR transits vectorially from e
160 A
central question is how members of this microbiota sense
161 A
central question is how nuclear substrates gain access t
162 A
central question is how specificity in cellular response
163 4-bp Smad binding elements (SBEs) in DNA, a
central question is how specificity of TGF-beta-induced
164 A
central question is how the balance between these two op
165 A
central question is how the motor system adapts in respo
166 One
central question is how the TRAMP complex, especially th
167 A
central question is how the X chromosome is recognized.
168 A
central question is how various stages of neuronal devel
169 The
central question is not whether performance on cognitive
170 A
central question is the biochemical mechanisms that make
171 of both TRPC and Orai1 channels by STIM1, a
central question is the role of each of the channels in
172 A
central question is thus how Xer/dif recombination is tu
173 A
central question is to what degree these coreceptors fun
174 A
central question is what kind of information controls th
175 A
central question is whether Abeta plays a direct role in
176 A
central question is whether and how DNA translocation is
177 A
central question is whether and how these flanking regio
178 A
central question is whether aneuploid phenotypes are the
179 In all cases, a
central question is whether crystallization pressure wil
180 A
central question is whether mutualisms persist because h
181 The
central question is whether phenotype heterogeneity, suc
182 A
central question is whether PPARgamma binding in macroph
183 The
central question is whether the rhythm is generated by a
184 Another
central question is whether these proteins act as genera
185 A
central question is, how are signals emanating from mult
186 A
central question is: does TRF function in vivo to transd
187 A
central question is: Why would cells mate with themselve
188 ongoing behavior for performance errors is a
central question of cognitive neuroscience.
189 A
central question of dynamics, largely open in the quantu
190 ult weakening during accelerated slip, and a
central question of earthquake physics is identifying th
191 tions that undergo sexual recombination is a
central question of epidemiology with profound implicati
192 y without treatment for many years remains a
central question of HIV research.
193 However, the
central question of how iNKT cells are activated by micr
194 tionship between them and contributes to the
central question of how language evolves.
195 However, the
central question of how these sugars are perceived in th
196 A
central question of marine ecology is, how far do larvae
197 tive understanding of human behaviour into a
central question of modern science.
198 ing mechanical imbalances are generated is a
central question of morphogenesis, with existing paradig
199 erned cellular identities are generated is a
central question of organogenesis.
200 A
central question of paramount importance is how structur
201 gy) and function of biological networks is a
central question of systems biology.
202 To address the
central question of the sequential control of these two
203 s of direction selectivity for 60 years, the
central question of their underlying algorithm remains u
204 The
central question of this review is whether these 2D phas
205 ar receptors for a single antigen raised the
central question of where B lymphocytes encounter antige
206 Additionally, within the glomerulus, the
central question of whether the primary filtration barri
207 However, the
central question of why it took these populations approx
208 The
central questions of bacterial ecology and evolution req
209 Here we address the
central questions of how stable isotropic growth of a br
210 and explaining this diversity is one of the
central questions of human biology.
211 es and maintain diversity remains one of the
central questions of microbiology, requiring an understa
212 omic techniques has raised expectations that
central questions of mixture toxicology such as for mech
213 revented systematic reviewers from answering
central questions of the review may include insufficient
214 We have investigated the
central questions of the roles of cytoskeletal elements
215 ar activities has provided new insights into
central questions of virology and host cell biology.
216 A
central question regarding alpha4beta1 function is how i
217 A
central question regarding helicase activity is whether
218 Thus, our data answer a
central question regarding regulation of Ku in DSB repai
219 One of the
central questions regarding helicase activity is whether
220 hemistry, cell biology, and physiology, many
central questions regarding the polymers themselves are
221 A
central question relates to mechanochemical coupling in
222 aeological and linguistic research; however,
central questions remain unresolved.
223 out the clinical immunology of AIDS, and the
central question remains of how CD4 cell loss relates to
224 mechanisms could account for synergy, but a
central question remains of whether synergism requires t
225 However, despite this wealth of attention, a
central question remains unanswered: "What regulates flu
226 However, a
central question remains unresolved: what type of magnet
227 Among those, the position of Ruminantia is a
central question,
still to be solved.
228 Our results can be used to explore
central questions such as whether microorganisms form a
229 Therefore, a
central question that any candidate mechanism has to ans
230 A
central question that emerges is whether immune and infl
231 ithin the context of anthropogenic change, a
central question that remains is how important are direc
232 gression, and early chemoprevention, but the
central question that remains is whether radical treatme
233 One of the
central questions that has occupied those disciplines co
234 This review points to some
central questions that need to be addressed to better un
235 The
central question this Perspectives in Diabetes raises is
236 A
central question to biology is how pathogenic bacteria i
237 controlling nuclear hormone receptors are a
central question to mammalian developmental and disease
238 models facilitates the genetic analysis of a
central question under investigation.
239 This is the
central question we address.
240 To address this
central question,
we performed paired recordings in prim
241 Guided by six
central questions,
we propose an integrative bottom-up a
242 To shed light on these
central questions,
we used all-atom, long-time-scale mol
243 ng and habit learning interact and answers a
central question:
What are the relative contributions of
244 Evolutionary origin of muscle is a
central question when discussing mesoderm evolution.
245 ng health care teams requires attention to 2
central questions:
who is on the team and how do team me