ライフサイエンスコーパス: cerebellar nuclei

1 ible selection of signals for output to deep cerebellar nuclei.

2 All injections labeled the deep cerebellar nuclei.

3 in Purkinje cells, but increased in the deep cerebellar nuclei.

4 ls can drive synaptic plasticity in the deep cerebellar nuclei.

5 strengthening of excitatory synapses in the cerebellar nuclei.

6 thout directly affecting neurons in the deep cerebellar nuclei.

7 ia nigra pars reticulata, pallidum, and deep cerebellar nuclei.

8 ced hyperexcitability of neurons in the deep cerebellar nuclei.

9 in the olfactory bulb, red nucleus, and deep cerebellar nuclei.

10 the cerebellar cortex and in the lower deep cerebellar nuclei.

11 ds located medially and in some cells of the cerebellar nuclei.

12 luence on candidate coding strategies in the cerebellar nuclei.

13 ons vulnerable to weaver, including the deep cerebellar nuclei.

14 learning in the pcd mice is mediated by the cerebellar nuclei.

15 it is expressed in Purkinje neurons and deep cerebellar nuclei.

16 r nuclei, inferior olivary complex, and deep cerebellar nuclei.

17 in neurons of the hippocampal formation and cerebellar nuclei.

18 ellar ataxia type 3 is not restricted to the cerebellar nuclei.

19 the cerebellar cortex but also involved the cerebellar nuclei.

20 both Purkinje cells and neurons of the deep cerebellar nuclei.

21 terminals were found variably in all of the cerebellar nuclei.

22 t axonal growth and synapse formation in the cerebellar nuclei.

23 layer, granule cell layer, and region of the cerebellar nuclei.

24 ntrols excitatory synaptic plasticity in the cerebellar nuclei.

25 ibition of cerebellar output neurons in deep cerebellar nuclei.

26 nhibits output from connected regions of the cerebellar nuclei.

27 inhibition of the inferior olive by the deep cerebellar nuclei.

28 ate from distinct output channels within the cerebellar nuclei.

29 sion at synapses from Purkinje cells to deep cerebellar nuclei and at vestibular synapses in mice.

30 ar cortex retrogradely labeled somata in the cerebellar nuclei and boutons in the ventrolateral thala

31 discrete populations of neurons in the deep cerebellar nuclei and brainstem vestibular nuclei.

32 vity, concomitantly increased signals in the cerebellar nuclei and cortex are consistent with finding

33 mossy fibers uniformly collateralize to the cerebellar nuclei and cortex underlies classic models of

34 /40 pS'--openings) in some patches from deep cerebellar nuclei and dorsal horn neurones.

35 rgic premotor projection neurons in the deep cerebellar nuclei and GABAergic neurons that feed back t

36 i, and the rhombic lip, which generates deep cerebellar nuclei and granule cells.

37 observed retrogradely labeled somata in the cerebellar nuclei and mossy fiber terminals in the cereb

38 Cerebellar nuclei and neighboring white matter displayed

39 rom layers four and five of the cortex, deep cerebellar nuclei and other localized brain regions.

40 ivity are abolished following lesions of the cerebellar nuclei and since hippocampal lesions prevent

41 hypothalamus, midbrain, pons, medulla, deep cerebellar nuclei and spinal cord, with tau-immunoreacti

42 The specific role of deep cerebellar nuclei and the cerebellar cortex in eyeblink

43 lized to specific areas within both the deep cerebellar nuclei and the cerebellar cortex.

44 In the vestibular and cerebellar nuclei and the dorsal medial superior tempora

45 ect to the corticonuclear projections to the cerebellar nuclei and the functional connections of the

46 cerebellar Purkinje cells and neurons in the cerebellar nuclei and vestibular nuclei of the Long-Evan

47 anscription factors define precursors of the cerebellar nuclei, and both Purkinje cells and granule n

48 thymic epithelium, pontine nuclei, fastigial cerebellar nuclei, and cerebral cortex.

49 Neurons in the cerebellar cortex, cerebellar nuclei, and inferior olive (IO) form a trisyn

50 onents simulating cerebellar cortex and deep cerebellar nuclei, and it received input from a middle t

51 ion was detected in the superior colliculus, cerebellar nuclei, and subpopulations of the medulla obl

52 iosis and vacuolation of neurons in the deep cerebellar nuclei, and the severe vacuolation of the cel

53 forebrain, the vestibular complex, the deep cerebellar nuclei, and the trapezoid body, a pattern tha

54 r nuclei, to the dorsolateral regions of the cerebellar nuclei, and to lateral regions of the superio

55 roups; the intermediate, medial, and lateral cerebellar nuclei; and the nodulus, the uvula, and the p

56 The projection neurons of the deep cerebellar nuclei are especially altered.

57 tor recovery, and lesions affecting the deep cerebellar nuclei are not fully compensated at any devel

58 Data on cerebellar nuclei are sparse.

59 Together, these data indicate that the cerebellar nuclei are under afferent control independent

60 ied to the thalamus from both vestibular and cerebellar nuclei, are positioned for distribution to wi

61 es motor disease phenotypes and identify the cerebellar nuclei as a therapeutic target for surgical i

62 tomy, ruling out both the cerebellum and the cerebellar nuclei as afferent sources.

63 immunolabeled axons terminated in all of the cerebellar nuclei as well as in the lateral and superior

64 uronal soma degeneration in the thalamus and cerebellar nuclei as well as striatum.

65 n a little-studied feedback pathway from the cerebellar nuclei back to the cerebellar cortex.

66 o a Purkinje cell or onto a cell in the deep cerebellar nuclei become eligible for plasticity only af

67 Fibers traversed the medial and intermediate cerebellar nuclei, but terminals appeared only occasiona

68 segment of the globus pallidus (GPi) and the cerebellar nuclei (Cb) to the thalamus in the monkey, we

69 KEY POINTS: Large premotor neurons of the cerebellar nuclei (CbN cells) integrate synaptic inhibit

70 ABSTRACT: Large projection neurons of the cerebellar nuclei (CbN cells), whose activity generates

71 ectly to large premotor neurons of the mouse cerebellar nuclei (CbN cells).

72 Neurons of the cerebellar nuclei (CbN) transmit cerebellar signals to p

73 hese climbing fibres send collaterals to the cerebellar nuclei (CbN).

74 Transduction was evident in the deep cerebellar nuclei, cerebellar Purkinje cells, the brains

75 t inhibitory GABA-glycinergic neurons of the cerebellar nuclei (CN) project profusely into the cerebe

76 The principal neurons of the cerebellar nuclei (CN), the sole output of the olivo-cer

77 what extent modulation of neuronal firing in cerebellar nuclei (CN), which are anatomically in an adv

78 g the factors that shape the activity of the cerebellar nuclei (CN).

79 Results suggest that lateral deep cerebellar nuclei contribute to visuospatial processing

80 Neurons of the cerebellar nuclei convey the final output of the cerebel

81 ibition of the cerebellar cortex on the deep cerebellar nuclei could treat oculopalatal tremor.

82 buted among many unlabeled cells in the deep cerebellar nuclei (DCbN).

83 nes of evidence have indicated that the deep cerebellar nuclei (DCN) are a site of memory storage for

84 Neurons of deep cerebellar nuclei (DCN) are spontaneously active, and di

85 The deep cerebellar nuclei (DCN) are the main output centers of t

86 The deep cerebellar nuclei (DCN) are the major output of the cere

87 n addition, we evaluated the use of the deep cerebellar nuclei (DCN) as a site for injection to facil

88 erebellum, PNNs are found around large, deep cerebellar nuclei (DCN) neurons and Golgi neurons and ar

89 components of the neuropil in the four deep cerebellar nuclei (DCN) of the rat's brain.

90 Inhibitory projection neurons in the deep cerebellar nuclei (DCN) provide GABAergic input to neuro

91 ay be initiated by hyperexcitability of deep cerebellar nuclei (DCN) secondary to loss of inhibitory

92 hin the mature fastigial pathway of the deep cerebellar nuclei (DCN), a region critical for balance a

93 Purkinje neurons and the neurons of the deep cerebellar nuclei (DCN), a site that has been implicated

94 ive to several brain regions, including deep cerebellar nuclei (DCN), globus pallidus, and thalamus.

95 ncy bursting activity in neurons of the deep cerebellar nuclei (DCN), which comprise the bulk of cere

96 ion is rebound firing in neurons of the deep cerebellar nuclei (DCN).

97 terior parietal cortex (area 5) and the deep cerebellar nuclei (DCN).

98 cluding in our study the neurons of the deep cerebellar nuclei (DCN).

99 on was examined with an emphasis on the deep cerebellar nuclei (DCN).

100 Tetrode recordings in the cerebellar nuclei demonstrate that focal stimulations of

101 f learning, and that there is a shift to the cerebellar nuclei during later stages.

102 hrony may shape the output of neurons in the cerebellar nuclei either via powerful inhibition by Purk

103 us, contralateral cerebellar cortex and deep cerebellar nuclei (FDR q < 0.05).

104 Neurons in the cerebellar nuclei fire at accelerated rates for prolonge

105 Neurons of the cerebellar nuclei fire spontaneous action potentials bot

106 and their postsynaptic target neurons in the cerebellar nuclei, fire action potentials at high, susta

107 uclei or by the combined action of inputs to cerebellar nuclei from mossy fiber collaterals and incom

108 We conclude that the deep cerebellar nuclei have a bilateral movement representati

109 Neurons of the cerebellar nuclei have basal firing rates of 10-20 Hz, d

110 Reversible inactivations of the cerebellar nuclei have directly implicated the cerebellu

111 Whereas cerebellar nuclei have long been thought to be preserved

112 For example, in the deep cerebellar nuclei, Hebbian patterns of coincident synapt

113 d between the cerebellar cortex and the deep cerebellar nuclei; (ii) the cerebellar cortex plays a sp

114 rtance of the cerebellar cortex and the deep cerebellar nuclei in eyeblink conditioning is unclear an

115 imaging allowed depiction of atrophy of the cerebellar nuclei in patients with Friedreich's ataxia a

116 ed imaging was used to assess atrophy of the cerebellar nuclei in patients with spinocerebellar ataxi

117 According to one concept, SLRs originate in cerebellar nuclei in response to direct inputs from coll

118 gically inhibiting the erratic output of the cerebellar nuclei in the mutant mice improved movement.

119 ve rise to both cerebellar neurons and extra-cerebellar nuclei in ventral hindbrain.

120 suggest that prolonged rebound firing in the cerebellar nuclei in vivo is most likely to occur when G

121 he parabrachial, lateral lemniscal, and deep cerebellar nuclei, in addition to cerebellar granule neu

122 prising the inferior olive, vermis, and deep cerebellar nuclei including the dentate nucleus during a

123 Purkinje cells inhibit diverse cells in the cerebellar nuclei, including small GABAergic nucleo-oliv

124 ut strikingly similar to neurons in the deep cerebellar nuclei, indicating a common role for intrinsi

125 ralis (VPLo) and nucleus X (X) following the cerebellar nuclei injections.

126 the output structures of the cerebellum, the cerebellar nuclei, integrate their inputs and influence

127 tentiation (LTP) of mossy fiber EPSCs in the cerebellar nuclei is controlled by synaptic inhibition f

128 ssy fiber varicosities in these parts of the cerebellar nuclei is positively correlated with the ampl

129 The muscimol infusions inactivated the cerebellar nuclei, lateral anterior lobe, crus I, rostra

130 In neurons of the cerebellar nuclei, long-term potentiation of EPSCs is in

131 ng microelectrode penetrations into the deep cerebellar nuclei (mainly nucleus interpositus) of monke

132 tibular signals from the vestibular and deep cerebellar nuclei may be important components of further

133 that can be achieved in this way in the deep cerebellar nuclei may be particularly important to allow

134 with relative increases in perfusion in deep cerebellar nuclei (medial, interposed, lateral), thalamu

135 rgely to the olfactory bulbs, midbrain, deep cerebellar nuclei, medulla, and spinal cord.

136 At synapses from Purkinje cells to deep cerebellar nuclei neurons (PC-->DCN), light- and electri

137 receptor-mediated monosynaptic IPSPs in deep cerebellar nuclei neurons by stimulation of Purkinje cel

138 caudal cerebellar vermis Purkinje cells and cerebellar nuclei neurons selective for actual linear ac

139 Unlike vestibular and deep cerebellar nuclei neurons, where a mixture of responses

140 represented by changes in the firing rate of cerebellar nuclei neurons.

141 kinje cells (which possess NR1 and 2D), deep cerebellar nuclei (NR1, 2A, 2B and 2D) and spinal cord d

142 unoreactivity in both the vestibular and the cerebellar nuclei of pigeons (Columba livia) and humming

143 immunoreactive fibers were found in all four cerebellar nuclei of the opossum.

144 t are excited by increased tonic activity in cerebellar nuclei or by the combined action of inputs to

145 onjugated to horseradish peroxidase into the cerebellar nuclei or internal segment of the globus pall

146 Within the cerebellar nuclei, PKC-delta-immunolabeled axons termina

147 ubstantia nigra and the lateral and internal cerebellar nuclei (present results).

148 The cerebellar nuclei primarily projected to posterior (VLp)

149 ing bilateral lesions targeting lateral deep cerebellar nuclei, rats were subjected to a bridge test

150 Neurons of the cerebellar nuclei receive GABAergic input from Purkinje

151 Neurons of the cerebellar nuclei receive synaptic excitation from cereb

152 brain stimulation directed to the interposed cerebellar nuclei reduced dystonia-like postures in thes

153 Within the cerebellar nuclei, reductions were significant when comp

154 e mice, which express Cre selectively in the cerebellar nuclei, retrogradely labeled somata in the in

155 rdings from the contralateral vestibular and cerebellar nuclei revealed elevated neuronal discriminat

156 MRI) of the cerebellar cortex and interposed cerebellar nuclei simultaneously during delay eyeblink c

157 cell layer, and loss of neurons in the deep cerebellar nuclei; spheroids and loss of myelinated axon

158 ies of these two projection neurons from the cerebellar nuclei tailor them for differential integrati

159 , enhanced connectivity was observed between cerebellar nuclei, thalamus, and basal ganglia, whereas

160 particularly observed in those parts of the cerebellar nuclei that have been implicated to be involv

161 d to pinpoint the exact location in the deep cerebellar nuclei that is necessary.

162 sions at atypical sites (e.g. thalamus, deep cerebellar nuclei) that are not typical for Lewy body-sp

163 messenger RNA levels were >/=30% in the deep cerebellar nuclei, the cerebellar cortex, inferior olive

164 itive neurons in the most medial of the deep cerebellar nuclei, the rostral fastigial nucleus, were c

165 In the deep cerebellar nuclei, the temporal increases in PBR paralle

166 ain, including, but not limited to, the deep cerebellar nuclei, the trapezoid body, the red nucleus,

167 racer injections into a distal target of the cerebellar nuclei, the ventrolateral thalamus, we observ

168 x spike firing revealed that feedback in the cerebellar nuclei to inferior olive to Purkinje cell loo

169 Here we verified that the pathway from the cerebellar nuclei to the cerebellar cortex in mice inclu

170 A feedback projection from the cerebellar nuclei to the medial auditory thalamus was id

171 g of information also allows neurons of deep cerebellar nuclei to use a simple averaging mechanism to

172 matergic neurons, namely neurons of the deep cerebellar nuclei, unipolar brush cells, and the late co

173 ilar to those recorded in the vestibular and cerebellar nuclei using identical testing paradigms, but

174 scent protein (rAAV1.miS1eGFP) into the deep cerebellar nuclei using magnetic resonance imaging guide

175 brainstem motor nuclei, inferior olive, deep cerebellar nuclei, vestibular nuclear complex, nucleus o

176 , oculomotor nucleus, substantia nigra, deep cerebellar nuclei, vestibular nucleus, and the thalamus.

177 Atrophy of the cerebellar nuclei was most pronounced in spinocerebellar

178 The volume of the cerebellar nuclei was reduced in the three patient group

179 ior to E12.5, with the exception of the deep cerebellar nuclei, we find that Math1 cells migrate out

180 ing and AT2 receptor mRNA levels in the deep cerebellar nuclei were also not affected by 3-acetylpyri

181 ed in the putamen, globus pallidus, and deep cerebellar nuclei, where the most dense areas of 8B3 imm

182 of Purkinje-cell axon terminals in the deep cerebellar nuclei, whereas the dendritic trees grew to n

183 ts were found in the interpositus and medial cerebellar nuclei wherein fluorodeoxyglucose uptake incr

184 Purkinje cells target the deep cerebellar nuclei, which are the output of the cerebellu

185 projection to most of the IO arises from the cerebellar nuclei, which are themselves subject to stron

186 P appears to match somatotopic maps of these cerebellar nuclei with the somatotopic map of projection

187 nce predict that their target neurons in the cerebellar nuclei would be largely inhibited unless Purk