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1 igh frequency of gene mutations in pediatric cerebrospinal AVFs, and show the predominance of RASA1 o
2 eta42, and tau proteins are established core cerebrospinal biomarkers; novel candidate biomarkers inc
3 nd a low white blood cell count on the first cerebrospinal examination (odds ratio, 9.83 for <5 vs. >
5 bic wounds (30%), blood (5.5%), urine (22%), cerebrospinal fluid (24%), ophthalmologic cultures (8%),
8 types of microorganisms spiked in artificial cerebrospinal fluid (ACSF) were directly detected simult
9 imal were pre-incubated in normal artificial cerebrospinal fluid (aCSF) while half were pre-incubated
12 plaques as evidenced by amyloid imaging and cerebrospinal fluid (CSF) Abeta1-42 (Abeta42) is an earl
13 mptoms (N=331) in the BioFINDER study, using cerebrospinal fluid (CSF) Abeta40 as a surrogate for amy
14 infected participants enrolled in a study of cerebrospinal fluid (CSF) abnormalities in syphilis unde
15 We studied whether continuous lower normal cerebrospinal fluid (CSF) amyloid beta1-42 (>/=640pg/ml)
16 tin C-Terminal Hydrolase L1 (UCHL1) in mouse cerebrospinal fluid (CSF) and Abeta in the mouse brains.
17 and neurofilament levels were determined in cerebrospinal fluid (CSF) and blood and analysed with re
18 iewing the literature to date on the role of cerebrospinal fluid (CSF) and blood biomarkers, we highl
19 peptide secondary structure distribution in cerebrospinal fluid (CSF) and blood plasma of 141 patien
20 p between SVD, multiple isoforms of Abeta in cerebrospinal fluid (CSF) and cortical Abeta in 831 subj
21 as a system that allows CNS perfusion by the cerebrospinal fluid (CSF) and interstitial fluid (ISF).
23 iral RNA was also detected in saliva, urine, cerebrospinal fluid (CSF) and semen, but transiently in
25 elin Basic Protein (MBP) and Tau proteins in cerebrospinal fluid (CSF) and serum, obtained from Multi
26 yloid precursor protein (APP) are present in cerebrospinal fluid (CSF) and their potential as biomark
28 mpal volume, normalized whole-brain volume), cerebrospinal fluid (CSF) biomarkers (amyloid-beta1-42,
29 ical disease, we sought to determine whether cerebrospinal fluid (CSF) biomarkers are intraindividual
30 bar punctures were performed and assayed for cerebrospinal fluid (CSF) biomarkers of AD pathology, in
32 The data show that LXR is a regulator of cerebrospinal fluid (CSF) both at the choroid plexus and
34 detection of human cytomegalovirus (hCMV) in cerebrospinal fluid (CSF) by polymerase chain reaction (
35 we showed that abnormal levels of Abeta42 in cerebrospinal fluid (CSF) can be detected before abnorma
36 min B6 (pyridoxal phosphate (PLP))) in human cerebrospinal fluid (CSF) can be used as indicators of t
38 he absence of markers of inflammation in the cerebrospinal fluid (CSF) commonly predicts the absence
43 quency and/or a delay in the positivity of a cerebrospinal fluid (CSF) culture or CSF antibody, parti
44 hile the concentration of Abeta(1-42) in the cerebrospinal fluid (CSF) decreases in APPswe, PS1M146V
45 central nervous system, resulting in either cerebrospinal fluid (CSF) discordance (viral load [VL] i
46 ts, perhaps owing to persistent HIV-1 RNA in cerebrospinal fluid (CSF) during antiretroviral therapy
47 nt diagnostic criteria involving analysis of cerebrospinal fluid (CSF) for parasites and/or pleocytos
48 study, we performed metabolomics analysis of cerebrospinal fluid (CSF) from cognitively intact elderl
49 undred twenty-two C57BL/6J mice infused with cerebrospinal fluid (CSF) from patients with anti-NMDAR
50 he apoE isoform amounts are not different in cerebrospinal fluid (CSF) from young normal controls, su
51 (>/= 55%), absent or low titers of serum and cerebrospinal fluid (CSF) immunoglobulin M, and occasion
52 We performed detailed neurological exams, cerebrospinal fluid (CSF) immunophenotyping and biomarke
53 her pyrimethamine lowered SOD1 levels in the cerebrospinal fluid (CSF) in patients carrying SOD1 muta
54 autism spectrum disorder (ASD) had increased cerebrospinal fluid (CSF) in the subarachnoid space (i.e
56 5, and inflammatory phenotype was defined by cerebrospinal fluid (CSF) leukocyte and cytokine concent
57 LTA4H promoter polymorphism, which predicted cerebrospinal fluid (CSF) leukocyte count and survival o
58 eak positive correlations between plasma and cerebrospinal fluid (CSF) levels for both Abeta42 and Ab
61 l protein that has demonstrated utility as a cerebrospinal fluid (CSF) marker of synaptic loss in AD.
63 he innate immune system, was associated with cerebrospinal fluid (CSF) markers of neuronal injury in
65 High levels of G6 dendrimers were found in cerebrospinal fluid (CSF) of injured animals with a CSF/
66 nt heavy chain (pNfH) levels are elevated in cerebrospinal fluid (CSF) of patients with amyotrophic l
67 in levels were significantly elevated in the cerebrospinal fluid (CSF) of Plxna4(-/-) mice and, in hu
69 e symptoms and measles antibody detection in cerebrospinal fluid (CSF) or medical record documentatio
70 disease-specific pathologic prion protein in cerebrospinal fluid (CSF) or olfactory mucosa (OM) sampl
73 SCS patients had constitutional symptoms, cerebrospinal fluid (CSF) pleocytosis, and hilar adenopa
74 orylated neurofilament heavy chain (pNFH) in cerebrospinal fluid (CSF) predict disease status and sur
75 sually self-limiting condition caused by low cerebrospinal fluid (CSF) pressure, usually due to CSF l
76 fied XCAT phantom with additional and edited cerebrospinal fluid (CSF) regions to produce voxel-level
79 ting Xpert MTB/RIF diagnostic performance on cerebrospinal fluid (CSF) samples are lacking in resourc
83 myloid1-42 (Abeta) levels were determined in cerebrospinal fluid (CSF) samples from all patients and
84 ing strategy to procure bone marrow (BM) and cerebrospinal fluid (CSF) samples from May 1, 2007, thro
85 al of 363 patients with HSV PCR results from cerebrospinal fluid (CSF) samples were included in this
89 and neonates with microcephaly and collected cerebrospinal fluid (CSF) specimens from 30 neonates.
91 strategy, defined as the absence of definite cerebrospinal fluid (CSF) sterilization or related morta
93 To test the hypotheses that (1) antemortem cerebrospinal fluid (CSF) tau levels correlate with post
94 ency virus (HIV) infection by evaluating the cerebrospinal fluid (CSF) to serum albumin quotient (QAl
95 tral distribution of macromolecules from the cerebrospinal fluid (CSF) to the brain and spinal cord r
96 asculature and the path of drainage from the cerebrospinal fluid (CSF) to the lymphatics remain poorl
98 lly was observed in animals with episodes of cerebrospinal fluid (CSF) viral rebound or sustained pla
99 pants with low or undetectable plasma VL and cerebrospinal fluid (CSF) VL prior to death who were enr
100 re unique to neuronal cells, are shed to the cerebrospinal fluid (CSF), and are detectable at low con
101 monocyte subpopulations in peripheral blood, cerebrospinal fluid (CSF), and brain biopsy material der
102 issues or prior probability maps (nlTPMs) of cerebrospinal fluid (CSF), gray matter (GM), and white m
103 ave been proposed for detection of prions in cerebrospinal fluid (CSF), most recently, the measuremen
104 which are diagnosed by detection of JCPyV in cerebrospinal fluid (CSF), often with the support of cer
105 The 102 included patients had: (1) serum, cerebrospinal fluid (CSF), or both that yielded a charac
106 ssion from MCI to AD were found for abnormal cerebrospinal fluid (CSF), phosphorylated tau (p-tau) (r
107 ngeal metastasis, or spread of cancer to the cerebrospinal fluid (CSF), which is a frequent and fatal
113 he ionic constituency of the bathing medium [cerebrospinal fluid (CSF)], or by electrical stimulation
115 ls (PBMCs; n = 72), seminal plasma (n = 20), cerebrospinal fluid (CSF; n = 36), dried blood spots (DB
117 om pyramidal cells, in the presence of human cerebrospinal fluid (hCSF), using a matched artificial c
119 s and the frequencies of immune cells in the cerebrospinal fluid (including B cells, T cells, and nat
122 levels of 38 mediators in serum (n = 78) and cerebrospinal fluid (n = 37) specimens from patients wit
127 osinor measures of each participant's serial cerebrospinal fluid Abeta concentrations and Abeta turno
128 the diurnal fluctuations in interstitial and cerebrospinal fluid Abeta levels observed in both the ro
129 ocial cognition and behavior, accumulates in cerebrospinal fluid after intranasal administration in m
130 lfonylurea receptor-1 is measurable in human cerebrospinal fluid after severe traumatic brain injury
131 the exchange of brain interstitial fluid and cerebrospinal fluid along a brain-wide network of periva
132 ll, players with PCS had significantly lower cerebrospinal fluid amyloid-beta levels compared with co
133 vement of the medial temporal lobe, abnormal cerebrospinal fluid amyloid-beta1-42 values, and proport
134 ls based on biomarkers of amyloid pathology (cerebrospinal fluid amyloid-beta42/amyloid-beta40 assay
136 mination, 4.1 [0.7] months), 7 who underwent cerebrospinal fluid analysis for ZIKV had positive findi
138 sonance imaging, electroencephalography, and cerebrospinal fluid analysis) and molecular data (prion
139 etagenomic next generation sequencing of his cerebrospinal fluid and brain biopsy tissue was performe
140 test further these small molecules in human cerebrospinal fluid and in a Caenorhabditis elegans mode
141 , cis P-tau is induced in cortical axons and cerebrospinal fluid and positively correlates with axona
143 ll subsets and immunoglobulin indices in the cerebrospinal fluid and whether retinal layer volumes al
146 11-labeled Pittsburgh Compound B (PiB), and cerebrospinal fluid assays of tau and phosphorylated tau
147 ividuals, elevated brain amyloid (defined by cerebrospinal fluid assays or positron emission tomograp
148 nds, Propionibacterium species in joints and cerebrospinal fluid associated with central nervous syst
150 ssed by endothelial cells of the mouse blood-cerebrospinal fluid barrier and of the blood-leptomening
151 ealthy CNS by endothelial cells of the blood-cerebrospinal fluid barrier and of the spinal cord menin
152 strate that leukemic cells transit the blood-cerebrospinal fluid barrier situated close to the dural
153 associated with brain injury as evaluated by cerebrospinal fluid biochemical markers for axonal damag
155 previously identified proSAAS as a potential cerebrospinal fluid biomarker in various neurodegenerati
156 out to have the least abnormal cognitive and cerebrospinal fluid biomarker profiles and the slowest c
157 heimer's disease neuroanatomical, cognitive, cerebrospinal fluid biomarkers and clinical profile, who
159 We relate these neuroimaging patterns to cerebrospinal fluid biomarkers, white matter hyperintens
163 evidence exists that differences in blood or cerebrospinal fluid chemokine concentration discriminate
164 ctivity disruption during polysomnogram, and cerebrospinal fluid collection the following morning for
166 96% (27 of 28) had cryptococcal meningitis (cerebrospinal fluid CRAG-positive) whereas 50% (7 of 14)
171 f meningeal LVs should allow manipulation of cerebrospinal fluid drainage and neuropathological proce
172 s or situations: cerebrospinal fluid shunts, cerebrospinal fluid drains, implantation of intrathecal
175 ther supportive information is obtained from cerebrospinal fluid examination and neurophysiological t
178 the formation of ependymal cells, disrupting cerebrospinal fluid flow and causing hydrocephalus.
179 lper T-cell subsets from peripheral blood or cerebrospinal fluid for cytokine production, gene expres
183 ve proteomics to identify protein changes in cerebrospinal fluid from children with Streptococcus pne
187 iagnosis, exercise-induced miRNA patterns in cerebrospinal fluid indicated distinct mechanisms for po
189 ons, vital signs, clinical laboratory tests, cerebrospinal fluid laboratory tests, and electrocardiog
190 We assessed for surgical complications (cerebrospinal fluid leakage and intracerebral haemorrhag
192 hetical preclinical AD groups using baseline cerebrospinal fluid levels of Abeta and tau or Abeta and
193 e lateral temporal lobe, and lower mean (SD) cerebrospinal fluid levels of tau (59.2 [32.8] vs 111.3
194 rmal expression of Keratin 9 in AD blood and cerebrospinal fluid may be a result of blood brain barri
195 tic end feet and defects in the synthesis of cerebrospinal fluid may be targeted by LXR agonists to f
196 adjusted for magnetic resonance imaging and cerebrospinal fluid measurements, sCD27 levels were asso
203 t here altered levels of gangliosides in the cerebrospinal fluid of amyotrophic lateral sclerosis pat
204 a markedly disturbed immune signature in the cerebrospinal fluid of cases that is consistent with imm
205 at shed PrP(c) (sPrP(c)) is increased in the cerebrospinal fluid of HIV-infected people with cognitiv
206 observed an increase in ACE2 activity in the cerebrospinal fluid of hypertensive patients, which was
207 ence essential for JCV neurovirulence and in cerebrospinal fluid of immunosuppressed patients with mu
208 f DN and CD21(low) B cells were found in the cerebrospinal fluid of MS patients compared with paired
209 influenza-infected mice and was elevated in cerebrospinal fluid of MS patients during relapse compar
210 even in the absence of inflammation; in the cerebrospinal fluid of MS patients they occur at a frequ
211 tion marker soluble CD27 (sCD27) measured in cerebrospinal fluid of patients at time of a first attac
215 in VH4-containing genes in B cells from the cerebrospinal fluid of patients with relapsing remitting
216 s from laboratory studies were notable for a cerebrospinal fluid opening pressure of 28 mm H2O and 8
217 xperience with the safety, tolerability, and cerebrospinal fluid penetration of the Src family kinase
218 ippocampal volume), neurofibrillary tangles (cerebrospinal fluid phosphorylated tau181 assay levels),
219 cteristics, including non-motor symptoms and cerebrospinal fluid phosphorylated-tau/total-tau ratio.
221 N/MCP, DN-to-pons, GP-to thalamus, and GP-to-cerebrospinal fluid ratios were measured and compared by
222 Dural cerebral veins (CV) are required for cerebrospinal fluid reabsorption and brain homeostasis,
223 underpinning mechanisms include the role of cerebrospinal fluid regulation as well as metabolic and
225 ologic and molecular testing using blood and cerebrospinal fluid samples can serve as a less expensiv
226 evel of tumor necrosis factor-alpha in those cerebrospinal fluid samples confirmed that ADAM17 was up
228 osorbent assay for ZIKV was performed on the cerebrospinal fluid samples of 7 of the 8 infants (88%),
229 Serum samples of cases and controls and cerebrospinal fluid samples of cases were tested for Zik
233 female (66.7%).Patients with CIS had higher cerebrospinal fluid sCD27 levels than control individual
234 er CRD (HR, 1.07; 95% CI, 1.03 to 1.11), and cerebrospinal fluid shunting (HR, 2.02; 95% CI, 1.07 to
235 fter the following procedures or situations: cerebrospinal fluid shunts, cerebrospinal fluid drains,
238 fonylurea receptor-1 is available, assessing cerebrospinal fluid sulfonylurea receptor-1 in larger st
241 f specific IgM antibodies in either blood or cerebrospinal fluid that appear in the second phase of t
242 post sacrifice and maintained in artificial cerebrospinal fluid to create near-physiological conditi
247 crease was associated with increase in total cerebrospinal fluid volume (r = 0.83, p < 0.001), and ch
249 e (r = 0.83, p < 0.001), and change in total cerebrospinal fluid volume was associated with ventricul
251 ing brain-predicted age with grey matter and cerebrospinal fluid volumes (themselves strong predictor
255 ension and the soluble CD14 concentration in cerebrospinal fluid were associated with lower fractiona
258 t contains a solution that closely resembles cerebrospinal fluid with the addition of extracellular m
259 s typically confined to the brain, eyes, and cerebrospinal fluid without evidence of systemic spread.
260 ce showed substantial levels of scFvs in the cerebrospinal fluid without significant effects on total
261 physiological fluids (blood, saliva, urine, cerebrospinal fluid) and brain tissue, it is unclear whe
262 cognitive, biomarker (structural imaging and cerebrospinal fluid) and other PD psychosis risk factor
263 Pittsburgh compound B and centrally analysed cerebrospinal fluid, a minority of subjects showed disco
264 nt mice, and IL-1beta is found in the blood, cerebrospinal fluid, and CNS lesions of MS patients.
265 cipation, decreased DA and DA metabolites in cerebrospinal fluid, and decreased availability, and rel
267 apeutic drug concentrations in the brain and cerebrospinal fluid, and that non-cross-resistant drugs
268 reatly to exosomal microRNAs (miRNAs) in the cerebrospinal fluid, and these exosomal miRNAs declined
269 be the effects of complex biofluids, such as cerebrospinal fluid, and thus has wide applicability.
271 -reaction (RT-PCR) assays for ZIKV in blood, cerebrospinal fluid, and urine, as well as antiflaviviru
272 eference for a novel face) robustly predicts cerebrospinal fluid, but not blood, oxytocin concentrati
273 lium (CPE) secretes higher volumes of fluid (cerebrospinal fluid, CSF) than any other epithelium and
274 (+) T cells pervade lymphatic organs and the cerebrospinal fluid, have a strong ability to produce di
275 des quantitative data on the dynamics of the cerebrospinal fluid, it can help test new therapies and
277 umes of whole brain, tissue compartments and cerebrospinal fluid, to test the hypothesis that HCA is
278 genic bacteria in positive culture of blood, cerebrospinal fluid, urine, or stool samples, including
281 rived measures of neurodegeneration/atrophy (cerebrospinal fluid-to-brain volume ratio, and hippocamp
299 .20%]) and intrathecal IgG synthesis (median cerebrospinal fluid/serum IgG index, 0.78 [IQR, 0.53-1.0
300 rmacokinetic findings of approximately 0.001 cerebrospinal fluid:plasma ratio further supported limit
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