ライフサイエンスコーパス: chair conformation

1 w that the cyclohexasilane monomer prefers a chair conformation.

2 gen bonds force these molecules to adopt the chair conformation.

3 nked to Trp-276 in TSR1 has an unusual (1)C4 chair conformation.

4 uce a considerable stabilization of the boat-chair conformation.

5 ts a boat rather than the typically observed chair conformation.

6 gher than that of 4 constrained in the alpha-chair conformation.

7 from the chair to the boat-like or inverted chair conformation.

8 seven-membered ring of retCPr adopts a twist chair conformation.

9 hat exo-[6.6.6.6]metacyclophane 6a assumes a chair conformation.

10 operates via a phenyl equatorial piperidine chair conformation.

11 icyclo[3.3.1]nonane bicyclic unit in a chair-chair conformation.

12 gles of the glucopyranose ring toward a half-chair conformation.

13 2.73 A) suggesting a tension stabilizing the chair conformation.

14 in free energy than their respective (4)C(1)-chair conformations.

15 )SO-skew boat, and less frequently, in (4)C1-chair conformations.

16 ecause of stabilization of the single A-ring chair conformations.

17 g is forced to adopt a highly strained 'half-chair' conformation.

18 , in contrast to this earlier study, an "all-chair" conformation (3B) is found to be the most stable

19 chain might be in a boat rather than in the chair conformation, a result supported by molecular dyna

20 rt that pyranose ring into the reactive half-chair conformation and that a hydrogen bond is formed be

21 The former stabilizes the steroid A-ring chair conformation and the latter locks the A-ring in th

22 states relative to the ground states of the chair conformations and destabilize pathways that occur

23 iling a Michaelis (ES) complex in a (1)C(4) (chair) conformation and a covalent glycosyl-enzyme inter

24 ,7-dioxaspiro[5.5]undecane, both rings adopt chair conformations, and both oxygens are axially dispos

25 The pyranose rings retain their (4)C1 chair conformation, as shown by molecular modeling and N

26 For deuterium-labeled cyclohexanes held in a chair conformation at -80 degrees C or lower, all four p

27 nformational rigidity and ability to adopt a chair conformation correlate strongly with experimental

28 which adopts either a chair-chair or a boat-chair conformation depending on the substituents in the

29 confirmed that (a) IdoA (1)C(4)- and (4)C(1)-chair conformations exchange on the microsecond time sca

30 oducts are consistent with cyclization via a chair conformation, Figure 1.

31 and black phosphorus display the more common chair conformation for their six-rings.

32 demonstrate that this ring assumes the beta-chair conformation in all cases, and the 1alpha-hydroxyl

33 25% of the energy necessary to form the half-chair conformation in glucose.

34 n reveals some distortion of the cyclohexane chair conformation in the solid state.

35 The chair conformation of the cyclohexyl group is clearly re

36 doaxial alkoxy group in the most stable half-chair conformation of the enolates, as shown in Schemes

37 rocyclic ring system to stabilize the active chair conformation of the parent gamma-secretase inhibit

38 uatorial orientation, resulting in a perfect chair conformation of the protecting group.

39 roxylated WIN analogues possessing a boat or chair conformation of the tropane ring were prepared and

40 ctive, a fact that is attributed to the half-chair conformation of these substances which reduces the

41 from substrate inhibition by the most stable chair conformation of UDP-D-xylose.

42 tituents to occupy the axial position in the chair conformation of various heterocycles.

43 The crown (chair-chair) conformations of the transition state account for

44 elds UDP-xylose adopting the relaxed (4)C(1) chair conformation (step 3).

45 e comprised of Sn3As3 puckered hexagons in a chair conformation that share all edges.

46 rable to an equatorial group of a piperidine chair conformation, this information provides very stron

47 hexaNAG substrate binds with all sugars in a chair conformation, unlike the family 18 chitinase which

48 ethyl substituent at N3 stabilizes the chair-chair conformation, whereas ethylacetate or 2-pyridylmet

49 lographic analysis of 5 established that the chair conformation which is adopted has all six C-O bond

50 nyl group at C4 carbon and presented a major chair conformation, which is prone to weaken the C4-O3 b

51 The molecule adopts a classic chair conformation with alternate C-F bonds aligned tria

52 s a mixture of two conformers possessing the chair conformation with the equatorial NMe group and dif

53 to explaining unusually large populations of chair conformations with axial substituents, noted previ

54 The nonplanar aliphatic ring exhibits two chair conformations with partial occupancies, each recap

55 (R(p))-5 and (R(p))-6 have chair conformations with the nucleobase substituent equa

56 d to pyranosyl ring flattening ((4)H(5) half-chair conformation) with little or no nucleophilic invol