1 The key
challenges facing a national vision surveillance system
2 The
challenges facing a new independent group leader, princi
3 Rod vision exemplifies a general
challenge facing adaptational mechanisms-balancing the b
4 rehensive review of current applications and
challenges facing AI use for IEI diagnosis and care.
5 tic attitudes, shedding theoretical light on
challenges facing American democracy.
6 One
challenge facing anti-influenza drug development is the
7 A major
challenge facing antigen-specific immunotherapies is ine
8 Here, we identify
challenges facing any attempt to develop C-tests, propos
9 It first discusses a number of
challenges facing any effort to communicate science in s
10 e the performance further, and discusses the
challenges facing APSC development for commercial applic
11 A major
challenge facing biodiversity informatics is integrating
12 -generation sequencing data is a significant
challenge facing bioinformatics researchers.
13 A fundamental
challenge facing biologists is to identify DNA binding s
14 Increasingly, the
challenge facing biologists is to relate the diverse dif
15 One
challenge facing biology is the elucidation of the funct
16 and/or animals is one of the most important
challenges facing biomedicine.
17 However, a
challenge facing bioprocesses is cost competitiveness wi
18 Given the
challenges facing biosensor technologists, it is natural
19 An important
challenge facing BMIs is that, over time, the number of
20 We also discuss
challenges facing broad deployment of CRISPR-based thera
21 Challenges facing C. jejuni researchers include determin
22 Here, we define ten key
challenges facing cancer immunotherapy, which range from
23 One of the major
challenges facing cancer researchers is the necessity to
24 One of the
challenges facing cancer therapy is to effectively and a
25 One of the major
challenges facing cancer therapy today is achieving spec
26 hich may offer a way to overcome some of the
challenges facing CAR T-cell development and clinical ut
27 th has been acknowledged as one of the major
challenges facing cardiology for the past four decades.
28 ction (HFpEF) represents one of the greatest
challenges facing cardiovascular medicine today.
29 The greatest
challenge facing cell therapy is the inability to contro
30 vo following implantation remains a critical
challenge facing cell-based approaches.
31 are connected in the cell is one of the big
challenges facing cell biologists.
32 ial vessels and partly explain the technical
challenges facing cerebral artery revascularization as c
33 duce lytic cycle in these cancers is a major
challenge facing clinical implementation.
34 rent vaccination strategies and we highlight
challenges facing clinical evaluation of ZIKV vaccine ca
35 this article is to articulate the 4 central
challenges facing clinical research at present--public p
36 In total, 81% of respondents considered the
challenges facing clinical research in AHCs to be urgent
37 Given the
challenges facing clinical translation of CD40/CD154 pat
38 One of the major
challenges facing clinical transplantation is antibody-m
39 HIV-related heart disease and discusses the
challenge facing clinicians who evaluate HIV-infected pa
40 The profound
challenges facing clinicians, who must prescribe drugs i
41 One of the main
challenges facing coffee production is the management of
42 elopment and in adulthood represents a major
challenge facing cognitive neuroscience.
43 up of behaviour-change messages and delivery
challenges facing community health workers.
44 otein complexity, the greatest bioanalytical
challenge facing comprehensive analysis of saliva sample
45 I outline key
challenges facing consumers, public health professionals
46 suite of nutrient transformations is a major
challenge facing contemporary biological oceanographers.
47 Sudden cardiac death (SCD) is a major
challenge facing contemporary cardiology.
48 Here, we highlighted the main
challenges facing CRISPR/Cas9-based treatments and propo
49 he structural transformation and discuss the
challenges facing CSP for such flexible molecules.
50 Drug addiction remains a key biomedical
challenge facing current neuroscience research.
51 o better understand and address the array of
challenges facing current HF drug development, so that f
52 illustrate how these ideas may also address
challenges facing current neural coding paradigms.
53 Recent advancements,
challenges facing current scaffold-based drug delivery a
54 assays developed around them, as well as the
challenges facing current sequencing platforms and their
55 Still, there are considerable
challenges facing current studies.
56 As a result of the
challenges facing current treatment and prevention parad
57 Among the
challenges facing data sharing in neuroscience, the prob
58 One of the major
challenges facing delivery of human vaccines in underdev
59 In this review, we detail these and other
challenges facing developers of cortical visual prosthes
60 ion to define and achieve a consensus on the
challenges facing development of therapeutic angiogenesi
61 therapeutic MEK inhibitors, underscoring the
challenges facing direct kinase inhibition in cancer.
62 In this Perspective, we analyze the
challenges facing discovery and discuss an emerging new
63 his study has better defined the development
challenges facing DNA methylation-based cancer-detection
64 A key
challenge facing drug discovery today is variability of
65 Finally, we describe
challenges facing each of the major theoretical perspect
66 ous system in response to the unique sensory
challenges facing each species.
67 In this Review, we highlight
challenges facing Earth's soil resources in the coming c
68 These findings highlight the
challenges facing echocardiographers when assessing the
69 After summarizing the
challenges facing effective TBIC implementation, we will
70 tion and provides timely analysis of the key
challenges facing efforts to achieve an appropriate bala
71 zon scanning approach was conducted in which
challenges facing EH professionals were provided by 1,73
72 uantum behaviour also presents an unresolved
challenge facing electronics at the few-nanometre scale:
73 Challenges facing enhanced recovery today include implem
74 this paper, the authors discuss some of the
challenges facing epidemiologists in the analysis and in
75 One
challenge facing eukaryotic cells is the post-translatio
76 al behaviors lie at the heart of many of the
challenges facing evolutionary biology, sociology, econo
77 been largely effective, perhaps the greatest
challenge facing fishery managers is how to deal with mi
78 e additional sources of variation to address
challenges facing food production.
79 cal reactions, concluding with the perceived
challenges facing further development of this field.
80 ior of target cells in vivo has been a major
challenge facing gene therapies.
81 at characterize today's medical care and the
challenges facing general internal medicine should spur
82 The future
challenges facing genetic epidemiology are considerable
83 ar level has been recognized as the greatest
challenge facing geneticists in the twenty-first century
84 One of the major
challenges facing genome-scan studies to discover diseas
85 The biggest
challenge facing genomic medicine today is the developme
86 onsultation focused on the opportunities and
challenges facing genomic AMR surveillance in a range of
87 to 200 GB depending on coverage), two major
challenges facing genomics laboratories are the costs of
88 Antimicrobial resistance is one of the great
challenges facing global health security in the modern e
89 el can be designed to rigorously reflect the
challenges facing HCMV vaccine trials, particularly thos
90 Long-term disorders are the main
challenge facing health-care systems worldwide, but heal
91 tion with these agents is among the greatest
challenges facing health care in the United States and w
92 Obesity is among the greatest
challenges facing healthcare systems with 20% of the wor
93 nderstands and plans to address the evolving
challenges facing healthcare, especially resource constr
94 bal diversity of HIV-1 represents a critical
challenge facing HIV-1 vaccine development.
95 damental/industrial milestones and remaining
challenges facing homogeneous/heterogeneous approaches a
96 One of the greatest
challenges facing human geneticists is the identificatio
97 imer's disease (AD) remains one of the grand
challenges facing human society.
98 rate of global biodiversity loss is a major
challenge facing humanity(1), as the consequences of bio
99 e biodiversity crisis is one of the greatest
challenges facing humanity, but our understanding of the
100 ently needed to help combat the major global
challenges facing humanity, such as climate change and r
101 erous climate change are two of the greatest
challenges facing humanity.
102 so offers a new solution to one of the major
challenges facing humankind.
103 ronmental crises are among the most pressing
challenges facing humankind.
104 A major chemical
challenge facing implementation of (225)Ac in targeted a
105 The single biggest
challenge facing in vivo imaging techniques is to develo
106 applicability and evolve in response to new
challenges facing integrative bioinformatics.
107 gement by the critical care societies in the
challenges facing intensivists.
108 One of the major
challenges facing investigators in the microbiome field
109 this improved outcome, there are still many
challenges facing investigators today.
110 We detail climate-related
challenges facing island Caribbean and SWIO communities
111 This addresses a key
challenge facing islet transplantation and importantly,
112 nt status of exome sequencing, the technical
challenges facing it, and its adaptation to diagnostics,
113 and describes progress toward overcoming the
challenges facing its adoption as a biofuel-production s
114 One of the major
challenges facing its production is the known co-product
115 Due to many
challenges facing its production, there are limited faci
116 One of the greatest
challenges facing large-scale colloidal synthesis of met
117 One of the major
challenges facing large-scale industrial applications ut
118 d salt, where feasible, can overcome endgame
challenges facing LF elimination programs.
119 This article highlights recent
challenges facing LTL strategies and describes the advan
120 A major
challenge facing malaria vaccine development programs is
121 esistance has emerged as one of the greatest
challenges facing malaria control.
122 g climate and dwindling resources is a grand
challenge facing mankind.
123 rce managers and policymakers to address the
challenges facing marine ecosystems.
124 Stability is one of the most important
challenges facing material research for organic solar ce
125 y engineering robust complex traits is a key
challenge facing metabolic engineering efforts to synthe
126 A
challenge facing metabolomics in the analysis of large h
127 One main
challenge facing metagenomic analysis is phylogenetic cl
128 es for infrastructure development and global
challenges facing migratory species, it is critical to i
129 h of chronically ill older adults is a major
challenge facing modern health care systems.
130 Here I describe practical
challenges facing modern microbial taxonomy, provide an
131 plex molecular settings underpin many of the
challenges facing modern organic synthesis.
132 Some major
challenges facing modern pneumonia etiology studies incl
133 and identifying binding partners of pRb, the
challenge facing molecular biologists and clinical oncol
134 ct cell types and cellular states is a major
challenge facing molecular biology.
135 The fundamental
challenges facing nanophotonics and electronics of the f
136 y' for atomic scale assembly is an important
challenge facing nanotechnology.
137 In this Perspective, we discuss key
challenges facing ncRNA therapeutics - including issues
138 e many regulatory, educational, and economic
challenges facing neurologists; further research is need
139 A great
challenge facing neuroscience is to understand how genes
140 One of the
challenges facing neuroscience entails localization of c
141 We also address some of the
challenges facing NGS-based studies of complex phenotype
142 gether, these findings highlight significant
challenges facing non-White scientists.
143 A critical scientific
challenge facing nonaqueous Li-O2 batteries is the elect
144 One of the key
challenges facing novel antiviral drug development for i
145 To meet the larger-scale conservation
challenges facing ocean ecosystems, several nations are
146 lly, we comment on the future directions and
challenges facing OECT circuits from both a fundamental
147 One
challenge facing omics association studies is the loss o
148 The key
challenge facing oncologists is how to administer chemot
149 With these
challenges facing opioid use disorder treatments immunop
150 One of the key
challenges facing organic photodiodes (OPDs) is increasi
151 A major
challenge facing our memory systems is how to integrate
152 Challenges facing our public schools demand a bold brand
153 Our work provides insight into the unique
challenges facing parasites of lytic phages and undersco
154 Finally, we discuss
challenges facing parasitic plant research and propose t
155 anagement were the greatest wound management
challenges facing patients and clinicians.
156 The
challenges facing pediatric cardiothoracic transplantati
157 Today's
challenges facing periodontal regenerative therapy conti
158 iscuss key thermal and operational stability
challenges facing perovskites, and give an outlook of fu
159 The
challenge facing pharmaceutical research is one of effec
160 Reports have outlined the
challenges facing physician-scientists, and programs hav
161 We discuss several ethical and practical
challenges facing physicians who wish to help their pati
162 Here, we review the conceptual and technical
challenges facing plant phenomics.
163 These uncertainties exemplify the
challenges facing policymakers, plans, and physicians as
164 eries on primary care--outlines the daunting
challenges facing primary care today.
165 A central and persistent
challenge facing protein structural analysis is the disc
166 A major
challenge facing public health is the increased incidenc
167 d discussing future directions and potential
challenges facing quantitative computational investigati
168 ing and integration are the most fundamental
challenges facing quantum science and technology.
169 n target definition is arguably the greatest
challenge facing radiation oncology, the greatest impact
170 Major
challenges facing RD to emerge as a new scientific field
171 multidimensional and collective character of
challenges facing refugee children and families calls fo
172 more realistic and complicated sense of the
challenge facing research and change efforts.
173 Finally, we discuss the outstanding
challenges facing research in this field and how they ca
174 A major
challenge facing researchers and clinicians is how to im
175 nesses of existing fate models, identify the
challenges facing researchers in developing and validati
176 There are several
challenges facing researchers in this field, including t
177 Finally, we outline the
challenges facing researchers who investigate the proces
178 One of the
challenges facing researchers working with viruses and g
179 ergetic materials, there are two significant
challenges facing researchers: 1) to develop ionic CHNO
180 residual uncertainty arises from particular
challenges facing revascularization trials.
181 proaches have been attempted, this remains a
challenge facing RNAi researchers.
182 Lastly, the
challenges facing RP photocatalysts and future research
183 A huge
challenge facing scientists is the development of adsorb
184 of this uncertainty is one of the principal
challenges facing scientists and clinicians in the field
185 vidence-based commentaries explores critical
challenges facing scientists and policymakers working to
186 ides an overview of the major pharmaceutical
challenges facing siRNA therapeutics, focusing on the de
187 study also highlights the opportunities and
challenges facing small molecule drug discovery for clas
188 Long-term allograft survival is a major
challenge facing solid organ transplantation.
189 ions (STIs), and teenage pregnancy are major
challenges facing South Africa.
190 creasing drought is one of the most critical
challenges facing species and ecosystems worldwide, and
191 A major
challenge facing structure-based drug discovery efforts
192 ata in terms of cellular function is a major
challenge facing systems biology.
193 We address two main
challenges facing systems neuroscience today: understand
194 A pressing
challenge facing the aviation industry is to aggressivel
195 portance for precision medicine, and a major
challenge facing the biomedical research community.
196 A
challenge facing the clinical implementation of AI stems
197 A
challenge facing the development of SSCs is aggregation
198 A major
challenge facing the discipline is the replacement of a
199 f TOP1-mediated repair mechanisms is a major
challenge facing the efficiency of TOP1-targetting thera
200 An important
challenge facing the field is how better to translate in
201 A major
challenge facing the field of cancer genome sequencing i
202 cathodes in Na-ion batteries is an important
challenge facing the field.
203 cancer treatment resistance is a significant
challenge facing the field.
204 A major
challenge facing the genetics of autism spectrum disorde
205 nt information continues being a substantial
challenge facing the Hispanic community.
206 and ultimately to cellular function is a key
challenge facing the life sciences.
207 enantiomerically pure chiral amines is a key
challenge facing the pharmaceutical and fine chemical in
208 To assess the implementation
challenge facing the Third Report of the Adult Treatment
209 A major
challenge facing the visual system is how to map such a
210 The
challenge facing the visual system is to extract the "me
211 Dehumidification is one of the key
challenges facing the air conditioning (AC) industry in
212 The major
challenges facing the application of this methodology to
213 Among many
challenges facing the battle against infectious disease,
214 monoclonal antibodies is one of the greatest
challenges facing the biotech industry.
215 of epicardial vessels are among the greatest
challenges facing the clinical cardiologist, and phenoty
216 o not have policies or mechanisms to address
challenges facing the clinical research mission.
217 Challenges facing the clinical translation of microsyste
218 epidemiological dynamics, is but one of the
challenges facing the coevolving fields of computational
219 fy TB, HIV/AIDS, and poverty as the greatest
challenges facing the community and suggest stigma, deni
220 EBOV replication is possibly one of the many
challenges facing the community of healthcare and policy
221 The
challenges facing the detection of low concentration of
222 Challenges facing the development of a universal S. aure
223 The issues and
challenges facing the development of different classes o
224 romise to address many of the aforementioned
challenges facing the development of new POC diagnostics
225 However, there are still significant
challenges facing the development of printable biomateri
226 reorganization provide some insight into the
challenges facing the discipline of plant pathology.
227 We review the
challenges facing the drug discovery industry, and discu
228 neering, and conclude with an outlook on the
challenges facing the evolution of biomaterials design f
229 als of cellular immunotherapy in cancer, key
challenges facing the field and exciting strategies that
230 Finally, this review discusses the
challenges facing the field and some exciting new molecu
231 Finally, the current
challenges facing the field are discussed and promising
232 ports in this area and describes some of the
challenges facing the field as it moves forward.
233 Major
challenges facing the field include understanding of the
234 and extends to some important questions and
challenges facing the field of DNA base damage repair.
235 Current
challenges facing the field of metabolomics include scal
236 We review the latest advancements and
challenges facing the field of molecular modelling and s
237 enhance the understanding of some of the key
challenges facing the field of STIs, and outlines new ap
238 l address the current progress and remaining
challenges facing the field to ultimately expand the sco
239 onists used to increase proteasome activity,
challenges facing the field, and applications beyond agi
240 o assess its strengths, consider the current
challenges facing the field, and set out new goals for i
241 strategies for immune cell engineering, and
challenges facing the field, with a particular emphasis
242 oteomimetic approaches and outline remaining
challenges facing the field.
243 Finally, we discuss
challenges facing the fields of biochemical modeling and
244 Meat discoloration is one of the
challenges facing the food industry, which affects both
245 der the remaining scientific and engineering
challenges facing the fulfilment of an artificial photos
246 he more significant and unique public health
challenges facing the global community, particularly aff
247 on in the changing climate are 2 significant
challenges facing the global community.
248 s described this task as one of the greatest
challenges facing the global health community and has id
249 r fresh insights on how to tackle a range of
challenges facing the natural world.
250 icient removal of H2 S is one of the crucial
challenges facing the natural-gas industry.
251 However, because of the technical
challenges facing the network-based study of miRNAs, man
252 s major biological questions and outline the
challenges facing the next generation of molecular tensi
253 second installment will focus on the current
challenges facing the pharmaceutical industry and Pharma
254 second installment will focus on the current
challenges facing the pharmaceutical industry and Pharma
255 The
challenges facing the PSC devices are emphasized with co
256 Among the
challenges facing the public health community is the nee
257 The authors discuss 6
challenges facing the recruitment and retention of physi
258 ise and context dependency are among the key
challenges facing the successful implementation of relia
259 tal implant placement is one of the greatest
challenges facing the surgeon.
260 The
challenges facing the translation of CRT into the clinic
261 NCE STATEMENT This study addresses two major
challenges facing the treatment of stroke in the era of
262 needs of this population is one of the major
challenges facing the U.S. health care system today and
263 One of the
challenges facing the UPS field is to delineate the comp
264 ficant progress toward solving long-standing
challenges facing the US health care system related to a
265 There are many
challenges facing the use of molecular biology to provid
266 tes that come from doing so, and the special
challenges facing the world over the next few decades.
267 t for heath in the past that is relevant for
challenges facing the world today, including the rise of
268 shortage of fresh water is one of the acute
challenges facing the world today.
269 e medicine and highlight key limitations and
challenges facing their inclusion in prediction models.
270 ll out these lessons and elaborate practical
challenges facing their model.
271 rlying their induction and activity, and the
challenges facing their potential clinical application.
272 oward their commercialization, and the major
challenges facing their retrofitting to existing cement
273 A major
challenge facing these batteries is finding electrolytes
274 ed materials in the biomedical field and the
challenges facing these exciting new tools both in terms
275 Challenges facing these methods and possible solutions a
276 principles and the scientific and technical
challenges facing these new fields.
277 viders to inform them about the psychosocial
challenges facing these patients.
278 The
challenges facing these professionals and research needs
279 In this review, we describe the
challenges facing this effort and propose research prior
280 Major
challenges facing this expression system are also outlin
281 The most important
challenges facing this field are the physicochemical pro
282 urthermore, we discuss the opportunities and
challenges facing this rapidly growing field.
283 and outline the conceptual and technological
challenges facing this research field.
284 The
challenges facing this target were examined for 7 reagen
285 One of the
challenges facing this technology is to further increase
286 logical phenomena in bacteria, the technical
challenges facing those of us who peer into bacterial ce
287 ularization remains one of the most critical
challenges facing tissue-engineering experts in their at
288 One major
challenge facing today's cancer researchers and toxicolo
289 The greatest
challenge facing transplantation today is how to increas
290 or neonatal porcine islets, the immunologic
challenges facing transplantation of xenogeneic islets,
291 Drug resistance is one of the most difficult
challenges facing tuberculosis (TB) control.
292 A major
challenge facing tumor-antigen targeting therapies such
293 These findings delineate the synthetic
challenges facing underdeveloped nanomaterials such as I
294 nt services should focus more on the special
challenges facing unemployed men with criminal history r
295 th care delivery is one of the most critical
challenges facing US health care.
296 data is one of the most pressing scientific
challenges facing us.
297 We will present the
challenges facing UV-induced drug delivery and some of t
298 Here we summarize
challenges facing vaccinology and immunology at the leve
299 ncentration continues to be one of the major
challenges facing wine producers.
300 Despite the
challenges facing xenotransplantation, the extreme need