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1                                      The key challenges facing a national vision surveillance system
2             Rod vision exemplifies a general challenge facing adaptational mechanisms-balancing the b
3                                          One challenge facing anti-influenza drug development is the
4               It first discusses a number of challenges facing any effort to communicate science in s
5                                      A major challenge facing biodiversity informatics is integrating
6 -generation sequencing data is a significant challenge facing bioinformatics researchers.
7                                A fundamental challenge facing biologists is to identify DNA binding s
8                            Increasingly, the challenge facing biologists is to relate the diverse dif
9                                          One challenge facing biology is the elucidation of the funct
10  and/or animals is one of the most important challenges facing biomedicine.
11                                   However, a challenge facing bioprocesses is cost competitiveness wi
12                                    Given the challenges facing biosensor technologists, it is natural
13                                 An important challenge facing BMIs is that, over time, the number of
14                                              Challenges facing C. jejuni researchers include determin
15                             One of the major challenges facing cancer researchers is the necessity to
16                             One of the major challenges facing cancer therapy today is achieving spec
17 th has been acknowledged as one of the major challenges facing cardiology for the past four decades.
18                                 The greatest challenge facing cell therapy is the inability to contro
19 vo following implantation remains a critical challenge facing cell-based approaches.
20  are connected in the cell is one of the big challenges facing cell biologists.
21 ial vessels and partly explain the technical challenges facing cerebral artery revascularization as c
22 rent vaccination strategies and we highlight challenges facing clinical evaluation of ZIKV vaccine ca
23  this article is to articulate the 4 central challenges facing clinical research at present--public p
24  In total, 81% of respondents considered the challenges facing clinical research in AHCs to be urgent
25                                    Given the challenges facing clinical translation of CD40/CD154 pat
26                             One of the major challenges facing clinical transplantation is antibody-m
27  HIV-related heart disease and discusses the challenge facing clinicians who evaluate HIV-infected pa
28                                 The profound challenges facing clinicians, who must prescribe drugs i
29 elopment and in adulthood represents a major challenge facing cognitive neuroscience.
30 otein complexity, the greatest bioanalytical challenge facing comprehensive analysis of saliva sample
31 suite of nutrient transformations is a major challenge facing contemporary biological oceanographers.
32        Sudden cardiac death (SCD) is a major challenge facing contemporary cardiology.
33 o better understand and address the array of challenges facing current HF drug development, so that f
34 assays developed around them, as well as the challenges facing current sequencing platforms and their
35                                    Among the challenges facing data sharing in neuroscience, the prob
36                             One of the major challenges facing delivery of human vaccines in underdev
37    In this review, we detail these and other challenges facing developers of cortical visual prosthes
38 ion to define and achieve a consensus on the challenges facing development of therapeutic angiogenesi
39 therapeutic MEK inhibitors, underscoring the challenges facing direct kinase inhibition in cancer.
40 his study has better defined the development challenges facing DNA methylation-based cancer-detection
41                                        A key challenge facing drug discovery today is variability of
42                         Finally, we describe challenges facing each of the major theoretical perspect
43 ous system in response to the unique sensory challenges facing each species.
44                 In this Review, we highlight challenges facing Earth's soil resources in the coming c
45                        After summarizing the challenges facing effective TBIC implementation, we will
46 tion and provides timely analysis of the key challenges facing efforts to achieve an appropriate bala
47  this paper, the authors discuss some of the challenges facing epidemiologists in the analysis and in
48                                          One challenge facing eukaryotic cells is the post-translatio
49 al behaviors lie at the heart of many of the challenges facing evolutionary biology, sociology, econo
50 been largely effective, perhaps the greatest challenge facing fishery managers is how to deal with mi
51 at characterize today's medical care and the challenges facing general internal medicine should spur
52 ar level has been recognized as the greatest challenge facing geneticists in the twenty-first century
53                             One of the major challenges facing genome-scan studies to discover diseas
54                                  The biggest challenge facing genomic medicine today is the developme
55  to 200 GB depending on coverage), two major challenges facing genomics laboratories are the costs of
56 el can be designed to rigorously reflect the challenges facing HCMV vaccine trials, particularly thos
57             Long-term disorders are the main challenge facing health-care systems worldwide, but heal
58 tion with these agents is among the greatest challenges facing health care in the United States and w
59                Obesity is among the greatest challenges facing healthcare systems with 20% of the wor
60 nderstands and plans to address the evolving challenges facing healthcare, especially resource constr
61 bal diversity of HIV-1 represents a critical challenge facing HIV-1 vaccine development.
62                          One of the greatest challenges facing human geneticists is the identificatio
63 e biodiversity crisis is one of the greatest challenges facing humanity, but our understanding of the
64 erous climate change are two of the greatest challenges facing humanity.
65 so offers a new solution to one of the major challenges facing humankind.
66                           The single biggest challenge facing in vivo imaging techniques is to develo
67  applicability and evolve in response to new challenges facing integrative bioinformatics.
68 gement by the critical care societies in the challenges facing intensivists.
69  this improved outcome, there are still many challenges facing investigators today.
70                         This addresses a key challenge facing islet transplantation and importantly,
71 nt status of exome sequencing, the technical challenges facing it, and its adaptation to diagnostics,
72 and describes progress toward overcoming the challenges facing its adoption as a biofuel-production s
73                             One of the major challenges facing large-scale industrial applications ut
74 d salt, where feasible, can overcome endgame challenges facing LF elimination programs.
75               This article highlights recent challenges facing LTL strategies and describes the advan
76                                      A major challenge facing malaria vaccine development programs is
77 esistance has emerged as one of the greatest challenges facing malaria control.
78 y engineering robust complex traits is a key challenge facing metabolic engineering efforts to synthe
79                                     One main challenge facing metagenomic analysis is phylogenetic cl
80 h of chronically ill older adults is a major challenge facing modern health care systems.
81                    Here I describe practical challenges facing modern microbial taxonomy, provide an
82                                   Some major challenges facing modern pneumonia etiology studies incl
83 and identifying binding partners of pRb, the challenge facing molecular biologists and clinical oncol
84 ct cell types and cellular states is a major challenge facing molecular biology.
85                              The fundamental challenges facing nanophotonics and electronics of the f
86 y' for atomic scale assembly is an important challenge facing nanotechnology.
87 e many regulatory, educational, and economic challenges facing neurologists; further research is need
88                                      A great challenge facing neuroscience is to understand how genes
89                  We also address some of the challenges facing NGS-based studies of complex phenotype
90                        A critical scientific challenge facing nonaqueous Li-O2 batteries is the elect
91                               One of the key challenges facing novel antiviral drug development for i
92        To meet the larger-scale conservation challenges facing ocean ecosystems, several nations are
93                                      The key challenge facing oncologists is how to administer chemot
94                                              Challenges facing our public schools demand a bold brand
95 anagement were the greatest wound management challenges facing patients and clinicians.
96                                      Today's challenges facing periodontal regenerative therapy conti
97 iscuss key thermal and operational stability challenges facing perovskites, and give an outlook of fu
98                                          The challenge facing pharmaceutical research is one of effec
99     We discuss several ethical and practical challenges facing physicians who wish to help their pati
100 Here, we review the conceptual and technical challenges facing plant phenomics.
101            These uncertainties exemplify the challenges facing policymakers, plans, and physicians as
102 eries on primary care--outlines the daunting challenges facing primary care today.
103                     A central and persistent challenge facing protein structural analysis is the disc
104                                      A major challenge facing public health is the increased incidenc
105 n target definition is arguably the greatest challenge facing radiation oncology, the greatest impact
106 multidimensional and collective character of challenges facing refugee children and families calls fo
107  more realistic and complicated sense of the challenge facing research and change efforts.
108                                      A major challenge facing researchers and clinicians is how to im
109 nesses of existing fate models, identify the challenges facing researchers in developing and validati
110                            There are several challenges facing researchers in this field, including t
111                      Finally, we outline the challenges facing researchers who investigate the proces
112                                   One of the challenges facing researchers working with viruses and g
113 ergetic materials, there are two significant challenges facing researchers: 1) to develop ionic CHNO
114 proaches have been attempted, this remains a challenge facing RNAi researchers.
115  of this uncertainty is one of the principal challenges facing scientists and clinicians in the field
116 ides an overview of the major pharmaceutical challenges facing siRNA therapeutics, focusing on the de
117  study also highlights the opportunities and challenges facing small molecule drug discovery for clas
118      Long-term allograft survival is a major challenge facing solid organ transplantation.
119 creasing drought is one of the most critical challenges facing species and ecosystems worldwide, and
120                                      A major challenge facing structure-based drug discovery efforts
121 ata in terms of cellular function is a major challenge facing systems biology.
122                          We address two main challenges facing systems neuroscience today: understand
123 portance for precision medicine, and a major challenge facing the biomedical research community.
124                                      A major challenge facing the discipline is the replacement of a
125 f TOP1-mediated repair mechanisms is a major challenge facing the efficiency of TOP1-targetting thera
126                                 An important challenge facing the field is how better to translate in
127                                      A major challenge facing the field of cancer genome sequencing i
128 cathodes in Na-ion batteries is an important challenge facing the field.
129 and ultimately to cellular function is a key challenge facing the life sciences.
130 enantiomerically pure chiral amines is a key challenge facing the pharmaceutical and fine chemical in
131                 To assess the implementation challenge facing the Third Report of the Adult Treatment
132                                      A major challenge facing the visual system is how to map such a
133                                          The challenge facing the visual system is to extract the "me
134                                    The major challenges facing the application of this methodology to
135                                   Among many challenges facing the battle against infectious disease,
136 monoclonal antibodies is one of the greatest challenges facing the biotech industry.
137 of epicardial vessels are among the greatest challenges facing the clinical cardiologist, and phenoty
138 o not have policies or mechanisms to address challenges facing the clinical research mission.
139  epidemiological dynamics, is but one of the challenges facing the coevolving fields of computational
140 fy TB, HIV/AIDS, and poverty as the greatest challenges facing the community and suggest stigma, deni
141 EBOV replication is possibly one of the many challenges facing the community of healthcare and policy
142                                              Challenges facing the development of a universal S. aure
143                               The issues and challenges facing the development of different classes o
144 romise to address many of the aforementioned challenges facing the development of new POC diagnostics
145 reorganization provide some insight into the challenges facing the discipline of plant pathology.
146                                We review the challenges facing the drug discovery industry, and discu
147 ports in this area and describes some of the challenges facing the field as it moves forward.
148                                        Major challenges facing the field include understanding of the
149  and extends to some important questions and challenges facing the field of DNA base damage repair.
150                                      Current challenges facing the field of metabolomics include scal
151 enhance the understanding of some of the key challenges facing the field of STIs, and outlines new ap
152                          Finally, we discuss challenges facing the fields of biochemical modeling and
153 der the remaining scientific and engineering challenges facing the fulfilment of an artificial photos
154 s described this task as one of the greatest challenges facing the global health community and has id
155 r fresh insights on how to tackle a range of challenges facing the natural world.
156 icient removal of H2 S is one of the crucial challenges facing the natural-gas industry.
157            However, because of the technical challenges facing the network-based study of miRNAs, man
158 s major biological questions and outline the challenges facing the next generation of molecular tensi
159 second installment will focus on the current challenges facing the pharmaceutical industry and Pharma
160 second installment will focus on the current challenges facing the pharmaceutical industry and Pharma
161                                    Among the challenges facing the public health community is the nee
162                        The authors discuss 6 challenges facing the recruitment and retention of physi
163 ise and context dependency are among the key challenges facing the successful implementation of relia
164 tal implant placement is one of the greatest challenges facing the surgeon.
165 needs of this population is one of the major challenges facing the U.S. health care system today and
166                                   One of the challenges facing the UPS field is to delineate the comp
167 ficant progress toward solving long-standing challenges facing the US health care system related to a
168                               There are many challenges facing the use of molecular biology to provid
169 tes that come from doing so, and the special challenges facing the world over the next few decades.
170  shortage of fresh water is one of the acute challenges facing the world today.
171 rlying their induction and activity, and the challenges facing their potential clinical application.
172 oward their commercialization, and the major challenges facing their retrofitting to existing cement
173 ed materials in the biomedical field and the challenges facing these exciting new tools both in terms
174                                              Challenges facing these methods and possible solutions a
175  principles and the scientific and technical challenges facing these new fields.
176 viders to inform them about the psychosocial challenges facing these patients.
177                                        Major challenges facing this expression system are also outlin
178                           The most important challenges facing this field are the physicochemical pro
179 and outline the conceptual and technological challenges facing this research field.
180                                   One of the challenges facing this technology is to further increase
181 logical phenomena in bacteria, the technical challenges facing those of us who peer into bacterial ce
182                                    One major challenge facing today's cancer researchers and toxicolo
183                                 The greatest challenge facing transplantation today is how to increas
184  or neonatal porcine islets, the immunologic challenges facing transplantation of xenogeneic islets,
185       These findings delineate the synthetic challenges facing underdeveloped nanomaterials such as I
186 th care delivery is one of the most critical challenges facing US health care.
187  data is one of the most pressing scientific challenges facing us.
188                          We will present the challenges facing UV-induced drug delivery and some of t
189 ncentration continues to be one of the major challenges facing wine producers.
190                                  Despite the challenges facing xenotransplantation, the extreme need

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