ライフサイエンスコーパス: change

1 younger individuals showing a faster rate of change.

2 much as half of the glacial-interglacial CO2 change.

3 red when assessing the impact of temperature change.

4 tein oligomerization from a minor structural change.

5 and respond to the health impacts of climate change.

6 larly under conditions of rapid evolutionary change.

7 an effective strategy to to mitigate climate change.

8 structure, local climates and microclimates change.

9 polymyxin E (PE) and PB via pH-induced color change.

10 be used to interrogate human lung metabolome changes.

11 change, assuming no adaptation or population changes.

12 luable parameters in determining parenchymal changes.

13 n, and led to retinoblastoma with anaplastic changes.

14 of CB1 in adipocytes and systemic metabolic changes.

15 skeleton may be susceptible to environmental changes.

16 tropical forest soils under future rainfall changes.

17 or but YFP is prone to photobleaching and pH changes.

18 l limitation is rigid commitment which never changes.

19 termine the life course progression of these changes.

20 on, changes in parallel with transcriptional changes.

21 criterion shifts independent of any sensory changes.

22 inding (84%), and neuroimaging without acute changes (82%).

23 3.3% had a deterioration in QoL, 9.2% had no change, 9.2% had a small improvement, 13.5% had a modera

24 descending paralysis (93%), no mental status change (91%), at least 1 ocular weakness finding (84%),

25 e consider psychological research on climate change - a quintessential intertemporal problem that imp

26 extinction debts, or the progress of climate change) against the rate at which spending appreciates i

27 roaches that incorporate multiple drivers of change and account for multiple sources of uncertainty a

28 a-ice loss is a leading indicator of climate change and can be attributed, in large part, to atmosphe

29 ver, other global changes-especially climate change and elevated atmospheric carbon dioxide concentra

30 ferentially expressed regions with >|2| fold change and p </= 0.05.

31 In this update, we describe recent changes and additions to our website, database and suite

32 ver, the relevance of individual residential changes and their importance among specific age and sex

33 voluntary head motion, frequency and B0 shim changes, and effects on data quality during real-time-co

34 s (8.7%) were associated with dyspnea, voice changes, and imminent asphyxiation.

35 Similar changes are present in a mouse alpha-synucleinopathy mod

36 Surprisingly, the resulting current changes are several orders of magnitude larger than that

37 However the mechanisms underlying these changes are unknown.

38 The values of texture indices and how they changed as a function of the activity distribution were

39 The hierarchy changed as the immune response progressed, and it was de

40 , P. aeruginosa showed drastic morphological changes as a result of cellular stress.

41 many mineral soils could undergo N-dependent changes as atmospheric CO2 concentrations rise, having g

42 DNA methylation changes associated with maternal smoking during pregnanc

43 in 1990-2099 under each scenario of climate change, assuming no adaptation or population changes.

44 task gait cost was defined as the percentage change between single- and dual-task gait velocities: ([

45 These results highlight how nanoscale changes can induce reactivity in 2D materials, which can

46 he northern forest carbon balance to climate change caused by changes in forest mortality.

47 , which allows them to function and adapt to changing cellular environments.

48 re regions, and depletion of topo-II did not change CENP-A levels.

49 fforts to predict the long-term effects of a changing climate on tropical forests must take into acco

50 nding how animal populations will respond to changing climatic conditions.

51 Amid the changing demographics of the US population and the risin

52 -related blood oxygen level-dependent signal changes demonstrated lower decreases relative to all oth

53 Treeline responses to environmental changes describe an important phenomenon in global chang

54 chanism was attributed to the conformational change driven by the collective hydrogen bonding and the

55 Global climate change drives sea-level rise, increasing the frequency o

56 disease when their abundances and activities change due to alterations in the environment or in the h

57 DOM as well as associated DBP formation are changed during an entire algal life cycle.

58 However, other global changes-especially climate change and elevated atmospher

59 st that ubiquitous unreliability of synaptic changes evinces metaplasticity that can provide a robust

60 e fastest reliable signal of true population change for species whose dynamics are driven by stochast

61 The overall mean rate of VF change for these patients was -0.12+/-0.51 dB/year over

62 omains undergoing significant conformational changes for affinity regulation.

63 =0.010) difference between the two groups in change from baseline in total cholesterol to HDL-cholest

64 Land-cover change from energy development, including solar energy,

65 ing would improve solubility, which led to a change from N-methylpyridone to a tetrahydropyranyl oxy-

66 Mean stereoacuity changed from a value of 263.3 +/- 135.1 before dichoptic

67 ynamically more stable goethite and hematite changed from complete and fast to incomplete and slow as

68 most recent electrocardiogram was profoundly changed from previous tracings, with marked and diffuse

69 RNase E/enolase distribution changes from membrane-associated patterns under aerobic

70 ren with histopathologic findings of minimal change glomerulopathy and FSGS, respectively.

71 Rheology parameters, color changes (h degrees , C *, DeltaE) microstructure (optica

72 e heterogeneous pattern of global vegetation change has been controlled by a combination of multiple

73 These changes have driven major reductions in reef growth pote

74 mma-subunit rotation into the conformational changes implicit in rotary catalysis.

75 ss mortality for cold and heat and their net change in 1990-2099 under each scenario of climate chang

76 ression was observed in 122 (15%) joints, no change in 564 (71%), and reversal in 108 (14%).

77 uring the follow-up period, the magnitude of change in 6MWD differed between IG and CG (P = 0.042), w

78 soil respiration rate (Rs) and its component change in a Dahurian Larch (Larix gmelinii) in Northeast

79 structure reveals a dramatic conformational change in a loop within the PL-2 epitope due to a serine

80 )2) at age 18-21 years, BMI at baseline, and change in BMI differed according to genetic risk based o

81 r than 1,200 kilometres, indicating either a change in bridgmanite cation ordering or a decrease in t

82 we propose a model in which a conformational change in BTN3A1 is a key event of pAg sensing that ulti

83 the majority of compounds had no systematic change in concentrations during equipment installation,

84 ization state, heme induces a conformational change in DGCR8.

85 Motion-induced change in emission (MICE) can be utilized as an effectiv

86 nvestigated the association of postchallenge change in glucagon during oral glucose tolerance tests (

87 cription is associated with a similar modest change in hepatitis B virus core antigen polypeptide (HB

88 tamin D and placebo groups did not differ in change in insulin sensitivity (0.02 +/- 2.0 compared wit

89 less, current broad scale representations of change in major land use classes impact modelled future

90 The adjusted change in mean estimated glomerular filtration rate from

91 verall, (68)Ga-PSMA PET/CT scanning led to a change in planned management in 51% of patients.

92 We found no significant change in prostate cell proliferation in treated mice wh

93 l biosensing approach involves measuring the change in sample viscosity using image processing and co

94 iates were identified as responsible for the change in selectivity of the heterogenized Mn catalyst.

95 We show that SiO2 first undergoes a change in Si-O coordination number from fourfold to sixf

96 optically-trapped vesicle revealed an abrupt change in the bending modulus of the bilayer which could

97 42]; p = 0.77; low-quality evidence), and no change in the duration of mechanical ventilation (mean d

98 NSAID use was not associated with a change in the incidence of PME among patients with diabe

99 be caused by aberrant salience leading to a change in the nature of the information that is encoded.

100 show that NADP(+) undergoes a conformational change in the oxidative half-reaction of FMOs.

101 rylation of a membrane protein can trigger a change in topological arrangement.

102 Although this change in transcription is associated with a similar mod

103 d in space and how their relative velocities change in various chemical contexts.

104 ber of leaf transcripts and metabolites were changed in response to genotype, and cell wall compositi

105 we investigated how motor cortical activity changed in the presence of an object independently of th

106 cardiovascular hospitalizations, and percent changes in 6-min walk distance) at 6 months.

107 Fe(3+) in the sample solution by monitoring changes in absorption from 540 to 580nm; the linear rang

108 polymerase activity and identify significant changes in activity between experiments.

109 Aging is accompanied by major changes in adipose tissue distribution and function.

110 ns can recruit brain reward systems to drive changes in affiliative behaviour.

111 sed analyses of selection and assessments of changes in amino acid properties provide evidence of pos

112 ially acquired between the cohorts, and that changes in antibody levels to Apical Membrane Antigen 1

113 large amounts of GFAP causes many molecular changes in astrocytes, including proteasome inhibition,

114 Relatively little is known about changes in bee community composition in the tropics, whe

115 tify several major time-dependent phenotypic changes in blood immune cell subsets that occur followin

116 ciations between HIV and food insecurity and changes in body composition over time.

117 macrophages, both of which occurred prior to changes in body weight, lending support to a causal rela

118 To study changes in both retinal structure and function during th

119 reduction in SK channel expression, but not changes in Ca(2+) -mediated activation of SK channels, c

120 resenting in vivo with extremely low or high changes in cardiac repolarization in response to a pharm

121 ng capacity, loss of astrocyte coupling, and changes in cell morphology.

122 Simultaneously, we measured changes in cerebral blood volume (CBV) as a proxy of dru

123 000 distal noncoding regions exhibit dynamic changes in chromatin accessibility between developmental

124 plexes modify histones but it is unclear how changes in chromatin states alter kinetics of transcript

125 No apparent temporal or dose-related changes in clinical status (specifically acute, Koch phe

126 levels of pathway activation, the signaling changes in developing tissues remain largely unknown.

127 We examined the associations between changes in dietary inflammatory potential and risk of co

128 Here we report on the extensive changes in distribution of mRNAs in the cell body and ax

129 es under various conditions, finding dynamic changes in each state.

130 s requires coordinated but poorly understood changes in epithelial cell-cell adhesion and cell motili

131 ificant, coherent and non-cell line specific changes in fatty acids, glycerophospholipids and carbohy

132 ations, likely related to maternal transfer, changes in food sources and starvation.

133 t carbon balance to climate change caused by changes in forest mortality.

134 ing, hematopoietic stem cells (HSCs) undergo changes in function and structure, including skewing to

135 Ser5P, the initiating form of RNAPII, but no changes in H3K27me3, at the promoters of affected endocr

136 mobile estuarine consumers over 5 months to changes in habitat availability in situ by comparing den

137 We analyzed changes in hepatitis B virus and hepatitis delta virus (

138 extinction and lack of extinction-dependent changes in hippocampal PSD CaMKII expression and S831 Gl

139 Overall, these differences highlight that changes in infant formula composition impact infant meta

140 er tasks and this positively correlated with changes in intracortical inhibition.

141 rns (drifting or inverting gratings) without changes in irradiance.

142 ly during activation, or that conformational changes in KCNQ1 alter its interaction with KCNE1.

143 A secondary objective was to assess changes in left ventricular mass.

144 The primary outcomes of the model were changes in life-years per 100 000 total population over

145 Our aim in this study was to assess changes in malaria morbidity in an area of Uganda with h

146 ng a large, water-filled pore in response to changes in membrane tension.

147 Changes in Nab3 binding are largely independent of alter

148 er various external conditions as well as to changes in network parameters arising from learning-depe

149 ess driven by genomic aberrations, including changes in nucleotide sequences.

150 We examined potential risk factors for changes in objectively assessed sleep duration within a

151 onse of a circumpolar seabird to large-scale changes in oceanographic conditions and indicates that m

152 Despite these changes in optical aerosol characteristics, increases in

153 ied in native conditions and enable sharp pH changes in order to mimic properly IgGs Fc domain/FcRn r

154 e (delta(13)C) record becomes insensitive to changes in organic carbon burial rate, due to counterbal

155 ress and inflammation and to explore whether changes in oxidative/nitrative stress are a function of

156 H2A.Z occupancy, but not distribution, changes in parallel with transcriptional changes.

157 ible inactivation, animals should still show changes in perceptual sensitivity mediated by the intact

158 cal analysis identified significant chemical changes in pet food as a result of processing, and allow

159 biological oscillations that schedule daily changes in physiology.

160 nd life expectancy at birth, attributable to changes in PM2.5.

161 s in single voxel receptive fields (vRFs) to changes in population-level representations.

162 We aimed to quantify changes in projected ranges and threat level by the year

163 These measurements reveal rapid changes in protein-RNA interactions within 1 min followi

164 were not associated with significant overall changes in quality or patient experience in the plans in

165 To assess changes in rates of 30-day readmission, we constructed a

166 biomass relative to baseline, but extensive changes in recruitment distribution.

167 Although changes in resting-state brain connectivity are a transd

168 put suppressed, rats were slower to adapt to changes in reward contingency, and OFC encoding of respo

169 tives included evaluation of adverse events, changes in sexual quality of life using the Cancer Rehab

170 Here we use fMRI to relate changes in single voxel receptive fields (vRFs) to chang

171 ative importance of host tree mortality from changes in soil chemistry following tree death.

172 the hyperexcitability of motoneurons and to changes in spinal sensory processing.

173 little is currently known regarding regional changes in spontaneous BOLD signal variability in the hu

174 ctrogenicity of the transporters accompanied changes in substrate specificity.

175 a reduced number of eosinophils in biopsies, changes in symptoms and endoscopic features are becoming

176 tions in dopamine-related genes (n = 45) for changes in tau transgene-induced behavioral defects.

177 d additive model (GAM) to examine how future changes in temperature and salinity could affect the dis

178 Changes in the 3'UTR composition of mRNAs can alter gene

179 Thus, we suggest that changes in the abundance of C4 grass and grazing herbivo

180 lay spontaneous calcium transients, and that changes in the activity patterns coincide with the cours

181 ation (OA) is projected to bring about sharp changes in the chemistry of coastal upwelling ecosystems

182 ization, stability and/or translation, while changes in the coding sequences lead to mRNAs encoding d

183 ve proteomics to characterize Hat1-dependent changes in the composition of nascent chromatin structur

184 ined, they are not associated with causative changes in the DNA methylome, which appears relatively i

185 Specific ion binding to such sites induces changes in the filter conformation, which play a key rol

186 -effects models showed small early favorable changes in the first few months post-TAVR, with a decrea

187 to anaerobic metabolism is brought about by changes in the levels of expression of relatively few ge

188 mmunogenic and tolerogenic, induce different changes in the lipid composition of cultured CD11c(+) ce

189 ients to healthy children, we establish that changes in the microstructure of the optic radiations an

190 We also extend the LOST model to accommodate changes in the modulatory structure over the duration of

191 efficients from previous studies to estimate changes in the numbers of deaths and in life years and l

192 the effect of space is equivalent to making changes in the payoff matrix, and once this is done, the

193 ter surgery, which was explained by opposite changes in the septum (decrease) and lateral (increase)

194 We aimed to determine whether changes in the serum levels of these noncoding RNAs are

195 are uncovering new evidence for evolutionary changes in the size and the number of neurons in the hum

196 By late century, we found modest changes in the spatial distribution of dominant species

197 ving shellfish prey size down with attendant changes in the tool sizes used by the monkeys.

198 e ability to monitor therapy-induced genomic changes in the tumour in an inexpensive and minimally in

199 uggest that training can lead to fundamental changes in the way attention alters the early cortical r

200 carbon burial rate, due to counterbalancing changes in the weathering of isotopically light organic

201 at transduce mechanical force into multifold changes in their intrinsic properties, we report on a me

202 e their complexity, listeners readily detect changes in these contexts.

203 urrence of slow structural modification with changes in trap state occupancy is likely a general feat

204 cent efforts to relate a century of observed changes in U.S. frost timing to various atmospheric circ

205 women in England in view of differences and changes in vaccination and screening uptake by ethnicity

206 ation Evaluation System sexuality subscales, changes in vaginal atrophy using a validated 4-point sca

207 ing flow, completely free from errors due to changes in viscosity.

208 No intervention produced significant changes in VO2 peak, kidney function, or urine albumin-t

209 nucleus accumbens is central to age-related changes in voluntary running.

210 These results demonstrate the potential for changes in water availability to impact plant-pollinator

211 food allergies has coincided with lifestyle changes in Western societies, such as dietary modificati

212 ucture is attributed to Pleistocene climatic changes, in which sky-islands acted as long-term refuges

213 y, we use Intergovernmental Panel on Climate Change (IPCC) Tier II guidelines to quantify the evoluti

214 ne expression but show that the direction of change is dynamic and unpredictable.

215 ation limitation is most severe and land use change is rapid.

216 What quantity of change is significant?

217 that the origin of the abnormal composition change is the difference in the thermodynamic properties

218 The net result of these changes is an accumulation of excess intracellular iron

219 The metabolic etiology of her lens changes is known, whereas the pathogenesis of ONHD is no

220 formation processing-suggesting that similar changes may critically, and more broadly, underlie the n

221 In particular, SRp55-mediated splicing changes modulate the function of the proapoptotic protei

222 retinography results; and retinal structural changes observed on clinical funduscopy as well as by ps

223 In exactly this region, structural changes occur in the ATP-induced opening of Hsp70 to all

224 he population-weighted median annual rate of change of catastrophic payment incidence was positive wh

225 nano-ablation, we assess the spatiotemporal changes of actomyosin-dependent force and stiffness alon

226 parameter, DeltaC1/2%, we compared relative changes of denaturation between peptides.

227 process that results in heritable epigenetic changes of gene regulation and trans-homologue interacti

228 der (PTSD), this study examined longitudinal changes of genome-wide blood DNA methylation profiles in

229 In patients with long-term aspirin use, the changes of molecular events in AM but not IM may be an i

230 y with lipid enrichment, but also with zonal changes of specific lipids and their associated metaboli

231 te matter signal abnormalities can mimic the changes of toxic leukoencephalopathy.

232 The capacity to tolerate climate change often varies across ontogeny in organisms with co

233 between England and Wales and Scotland, and changes over time in Scotland.

234 We compared changes over time in the use of assisted ventilation and

235 ng the response of precipitation to external changes over typical basins.

236 Changes-over-time temperature, blood pressure, and heart

237 resulted in either gain- or loss-of-function changes, part of which was attributable to cysteine-medi

238 Among them, eight proteins showed the same changing patterns in both 1 SL and 2 SL.

239 nant pH1N1 virus encoding these 6 amino acid changes (pH1N1/NSs-6mut) induced lower levels of proinfl

240 The package is developed based on a change-point based method with optimal computational com

241 A change-point detection is proposed by using a Bayesian-t

242 ed on the shortest Hamiltonian path, and the change-point is estimated by using ratio cut.

243 This genomic change probably contributed to the high evolutionary rat

244 imaging report to denote intended management changes (Q2), and one 6 mo later (Q3) to verify whether

245 it neutralizes by inhibiting conformational changes required for entry.

246 s describe an important phenomenon in global change research.

247 The precision of the fold-change response was observed throughout the signaling du

248 pean forest tree species under three climate change scenarios.

249 se CRISPR base editors to knock out genes by changing single nucleotides to create stop codons.

250 nother monomer that undergoes conformational changes stabilizing the dimer assembly.

251 low enough for observing subtle near-surface changes such as water content variations and permafrost

252 adjust behavior in response to environmental changes, such as fluctuations in food abundance, to maxi

253 e spatial magnitude and direction of climate change, support a convenient initial assessment of poten

254 was remarkably more sensitive to temperature change, than classical vesicles.

255 Immunosenescence is a series of age-related changes that affect the immune system and, with time, le

256 interrogating the types of deep evolutionary changes that have restructured developmental gene regula

257 Mutations of the beta-catenin pathway change the phenotype of a common nevus with BRAF mutatio

258 Excluding cases of TRM did not substantively change the results.

259 eptual learning refers to how experience can change the way we perceive sights, sounds, smells, taste

260 ns in the genomic context using CRISPR/Cas9, changed the splicing pattern.

261 The results changed the therapeutic plan in 84 patients (80.8%).

262 Splicing in the 5'-UTR also changes the inclusion of long upstream ORFs (uORFs).

263 formance by adjusting the applied voltage or changing the electrode design.

264 e of the metal ligand cooperative reactions, changing the energetics of the process when different de

265 cellular calcium dynamics can be modified by changing the levels of SERCA, IP3R, and/or RyR.

266 Rather than changing the oligomerization state, heme induces a confo

267 ze of the nanopores alone, it is possible to change their behavior from dampers to molecular springs.

268 is possible that collagen-binding cells may change their phenotypic traits.

269 pe, and that altering tumor metabolism could change therapeutic outcome.

270 se therapies that are ineffective, modify or change therapy, and avoid disease complications.

271 n to this trio of temperature, oxygen and pH changes through heterotrophic plasticity.

272 rovides a path for lipids in scramblases has changed to form an enclosed aqueous pore that is largely

273 of betaLG, BSA, and lysozyme, while alphaLA changed to its NIS-bound state instead of the native sta

274 VFD2 of TAS1R2 leads to major conformational changes to form a TM6/TM6 interface between TMDs of TAS1

275 1) weight loss program supporting behavioral changes to promote a 5% weight loss.

276 nfocal microscopy of live animals to observe changes to spermathecal actomyosin network organization

277 Integrins undergo large-scale conformational changes upon activation.

278 S measurements, revealing dynamic structural changes upon iron binding and core formation, as reflect

279 ble nanoplasmonic patch whose original color changes upon sun exposure due to its UV-responsive capab

280 Here, we perform a continent-wide climate change vulnerability assessment whereby we compare the b

281 Furthermore, aortic relative area change was associated with left ventricular ejection fra

282 The process of this phase-change was followed by in situ variable temperature powd

283 To determine whether behaviour change was related to group attendance, we used random e

284 Among the strongest changes was also induction of IL6 in resistant cells and

285 Without change, we estimate that the population of sub-Saharan A

286 These changes were accompanied by increased accumulation of in

287 These changes were associated with an increase in sympathetic

288 e 6 mo later (Q3) to verify whether intended changes were in fact implemented.

289 Treatment-specific changes were observed only during cognitive reappraisal

290 Drusen and RPE changes were seen in the peripheral retina, anterior to

291 Most induced changes were TCF dependent, but TCF-independent TSSs exh

292 , the principal exposed epitope that did not change when pdm2009 displaced previous seasonal H1 virus

293 eeper knowledge of how our biological clocks change with age may create valuable opportunities to imp

294 ound that the interfacial resistance did not change with increase in the thickness of the metal coati

295 story may miss clinically actionable genetic changes with established implications for cancer screeni

296 ications and a dynamic view of RNA structure changes with increased numbers of 2-5-linkages in the sa

297 scientific methods of this 21st century are changing with the increased power and speed of computers

298 itro (false discovery rate, </=0.001; 2-fold change) with 557 showing decreased and 329 showing incre

299 ironment lead to distinctive gene expression changes within a cell.

300 amide-rich membrane areas promote structural changes within the plasma membrane that segregate membra