ライフサイエンスコーパス: chaperone-mediated autophagy

1 taining KFERQ-like sequences are degraded by chaperone mediated-autophagy.

2 e key glycolytic enzyme hexokinase-2 through chaperone-mediated autophagy.

3 es lysosomal RhoH uptake and degradation via chaperone-mediated autophagy.

4 ulation of other autophagic pathways such as chaperone-mediated autophagy.

5 hat are degraded by the lysosomal pathway of chaperone-mediated autophagy.

6 s include macroautophagy, microautophagy and chaperone-mediated autophagy.

7 down of proteins targeted for destruction by chaperone-mediated autophagy.

8 els and activities of the main components of chaperone-mediated autophagy.

9 importance of KFERQ motifs in substrates of chaperone-mediated autophagy.

10 We investigated chaperone-mediated autophagy, a lysosomal import pathway

11 been proposed to be a targeting sequence for chaperone-mediated autophagy, a lysosomal pathway of pro

12 and VI, are enriched in lysosomes with high chaperone-mediated autophagy activity as expected for su

13 Furthermore, Nrf2 in astrocytes delayed chaperone-mediated autophagy and macroautophagy dysfunct

14 n mutant p53 expression by the activation of chaperone-mediated autophagy and potential pharmacologic

15 re, we focus on two autophagic pathways, the chaperone-mediated autophagy and the endosomal microauto

16 old" (22-month-old) rats show lower rates of chaperone-mediated autophagy, and both substrate binding

17 is pivotal to the process of macroautophagy, chaperone-mediated autophagy, and endosomal microautopha

18 LAMP2 is needed for chaperone-mediated autophagy, and its expression improve

19 e and a specific type of vacuolar autophagy, chaperone-mediated autophagy, are involved in the degrad

20 nate protein Hsc73 (a key protein marker for chaperone-mediated autophagy), beclin 1 (a mammalian aut

21 phate dehydrogenase, a classic substrate for chaperone-mediated autophagy, by more than 90%, whereas

22 Inhibition of chaperone-mediated autophagy caused accumulation of inac

23 Chaperone-mediated autophagy (CMA) also mediated resista

24 ve identified a compensatory upregulation of chaperone-mediated autophagy (CMA) in different cellular

25 Chaperone-mediated autophagy (CMA) is a highly regulated

26 mal degradation of the HIF-1alpha subunit by chaperone-mediated autophagy (CMA) is a major regulator

27 Chaperone-mediated autophagy (CMA) is a selective lysoso

28 Chaperone-mediated autophagy (CMA) is a selective mechan

29 Chaperone-mediated autophagy (CMA) is a selective mechan

30 Chaperone-mediated autophagy (CMA) is a selective mechan

31 Chaperone-mediated autophagy (CMA) is a selective pathwa

32 Chaperone-mediated autophagy (CMA) is a selective type o

33 Chaperone-mediated autophagy (CMA) is activated in respo

34 Chaperone-mediated autophagy (CMA) serves as quality con

35 Chaperone-mediated autophagy (CMA) targets soluble prote

36 Chaperone-mediated autophagy (CMA), a selective form of

37 ave shown that alpha-syn can be degraded via chaperone-mediated autophagy (CMA), a selective lysosoma

38 Chaperone-mediated autophagy (CMA), a selective mechanis

39 The activity of chaperone-mediated autophagy (CMA), a selective pathway

40 Cystinosis is associated with defects in chaperone-mediated autophagy (CMA), but the molecular me

41 graded during both macroautophagy and during chaperone-mediated autophagy (CMA), the latter of which

42 e found LRRK2 to be degraded in lysosomes by chaperone-mediated autophagy (CMA), whereas the most com

43 LAMP-2A is required for chaperone-mediated autophagy (CMA), which promotes Ag ca

44 utophagy-macroautophagy, microautophagy, and chaperone-mediated autophagy (CMA)-contribute to degrada

45 Here we find that ER disturbance activates chaperone-mediated autophagy (CMA).

46 adation through a type of autophagy known as chaperone-mediated autophagy (CMA).

47 70 kDa (hsc70), two essential components of chaperone-mediated autophagy (CMA).

48 ane protein type 2a (lamp2a), a receptor for chaperone-mediated autophagy (CMA).

49 Chaperone-mediated autophagy controls the degradation of

50 orm A (Lamp-2a), an established component of chaperone-mediated autophagy, enhanced cytoplasmic autoa

51 omotes the degradation of mutant p53 through chaperone-mediated autophagy in a lysosome-dependent fas

52 ls and HIF-1 activity, whereas activators of chaperone-mediated autophagy, including 6-aminonicotinam

53 ompanied by impairment of macroautophagy and chaperone-mediated autophagy, increased levels of total

54 sence of macroautophagy, an up-regulation of chaperone-mediated autophagy induced resistance to these

55 ses, yielding fragments that translocate via chaperone-mediated autophagy into the endosomal network

56 f the host protein turnover pathway known as chaperone-mediated autophagy involved in transport of cy

57 , aberrant interactions with tubulin and the chaperone-mediated autophagy machinery as observed by ot

58 Thus, chaperone-mediated autophagy modulates the neuronal surv

59 he BCR and cytoplasmic proteins that use the chaperone-mediated autophagy pathway.

60 ocated into lysosomes for degradation by the chaperone-mediated autophagy pathway.

61 -Lys97), overlapping the recently identified chaperone-mediated autophagy recognition motif and a hig

62 In a neuronal cell line, we found that chaperone-mediated autophagy regulated the activity of m

63 process has selectivity and is distinct from chaperone-mediated autophagy that occurs in lysosomes.

64 To determine if EGF regulates chaperone-mediated autophagy through PI3K signaling, thi

65 protein type 2a that acts as a receptor for chaperone-mediated autophagy was responsible for decreas

66 In cultured cells, chaperone-mediated autophagy, which is responsible for t