ライフサイエンスコーパス: chelating

1 conventional heteroditopic ligand capable of chelating a metal center by way of covalent and noncoval

2 The metal chelating abilities (34.92-57.38mgEDTA/g) and in vitro a

3 ical scavenging, reduction of metal ions and chelating abilities against ferrous ions.

4 ) radical scavenging activities, ferrous ion chelating abilities and reducing power results showed th

5 All these polyanils showed good chelating abilities toward trivalent boron fragments suc

6 n preventers and compounds with reducing and chelating abilities.

7 al scavenging capacity (50.18-86.79%), metal chelating ability (0.21-8.15%), ferric ion reducing powe

8 assay (67.66%), ABTS assay (78.81%), Fe(2+) chelating ability (51.20%), hydroxyl assay (60.95%) and

9 ical, ABTS radical, hydroxyl radical, Fe(2+) chelating ability and reducing power.

10 DPPH, hydroxyl and peroxyl; and Ferrous Ion-chelating Ability Assay).

11 ty measurements, i.e. the reducing power and chelating ability measurements, for appropriate comparis

12 was significantly lower than BHT, and metal chelating ability of HBMe also showed a strong inhibitio

13 es smaller than 5kDa were evaluated for iron chelating ability through measurements of iron solubilit

14 Cu(2+)-chelating ability was significantly correlated to FRAP,

15 idant activity (57.11 mug mL(-1) Ferrous Ion-chelating Ability, 221.46 mug mL(-1) Hydroxyl radical sc

16 0.05) correlations were obtained with Fe(2+)-chelating ability.

17 ckness, and the results demonstrate that the chelating action and dispersing effect of EDTA is critic

18 ylhydrazyl radical inhibiting and Fe(2+) ion chelating activities (IC50 25.05 and 350.7muM, respectiv

19 en quenching, reducing power and ferrous ion-chelating activities of CS were also pronounced.

20 , 3.6 and 0.035 for scavenging, reducing and chelating activities, respectively.

21 ing activities (p<0.05), but limited ferrous chelating activities.

22 radical scavenging, reducing ferric ions and chelating activities.

23 ntiradical efficiency (4.62 mM TE/100 g) and chelating activity (252 muM EDTA/100 g).

24 hing inhibition (91.75 +/- 0.22%) and Cu(2+)-chelating activity (74.53 +/- 0.58%).

25 activity (IC50=39.33 +/- 3.2 mug/mL), metal chelating activity (IC50=56.51 +/- 3.6 mug/mL) and inhib

26 All the fractions demonstrated low iron chelating activity and did not inhibit oxidation in a so

27 cavenging activity, reducing power, Fe(2)(+) chelating activity and inhibition of lipid oxidation in

28 y good radical scavenging activity, Fe(2)(+) chelating activity and reducing power while the fraction

29 enging activity and possessed increased iron-chelating activity and reducing power.

30 were analyzed for antioxidant activity, Iron chelating activity and total phenolic content.

31 radical scavenging, reducing activities and chelating activity as well as decreased lipid oxidative

32 The metal chelating activity of flour blends varied from 62.0% to

33 ng enzyme (ACE), and the antiradical and ion chelating activity of peptides from different protein fr

34 ity (RSA) on DPPH, ascorbic acid content and chelating activity on Fe(2+) of Pleurotus citrinopileatu

35 In contrast, reducing power and iron chelating activity seemed to be caused by peptides.

36 s showed significantly (p 0.05) higher metal chelating activity than other fractions.

37 hocyanin content and 16.6-43.2% higher metal chelating activity than the cultivars grown in plains (9

38 wer assay (FRAP), ferrous ion (Fe(2+)) metal chelating activity, and DPPH free radical-scavenging act

39 assay showed 71.3% inhibition and 65.8% Iron chelating activity.

40 eds are good source of antioxidants and Iron chelating activity.

41 WF possessed moderate copper chelating activity.

42 rinopileatus showed higher ascorbic acid and chelating activity.

43 , 3.76-6.76 mg ascorbic acid and 60.25-82.7% chelating activity.

44 All sub-fractions showed high Fe(2+) chelating activity.

45 scavenging activity, reducing power and iron chelating activity.

46 gramme that included treatment with the oral chelating agent 2,3-dimercaptosuccinic acid (DMSA, succi

47 n (MMC) scaffold which combined a radiometal chelating agent and fluorescent dye into a single moiety

48 at trace level using 8-hydroxyquinoline as a chelating agent and lanthanum(III) as a carrier element

49 optimization with regard to the radionuclide-chelating agent and the linker moiety between chelator a

50 Treating infant formulas with the chelating agent diethylene triamine pentaacetic acid (DT

51 The chelating agent ethylenediaminetetraacetate (EDTA) selec

52 A NOTA ligand is the chelating agent for the (68)Ga, and two related opioid p

53 ral DMSA was a pharmacodynamically effective chelating agent for the treatment of severe childhood le

54 been developed using the incorporation of a chelating agent in a common organic solvent, dimethyl su

55 or precursor cadmium complex that works as a chelating agent in order to increase optical and electri

56 suggests the importance of the alkali metal chelating agent in the reversibility of dinitrogen bindi

57 uman growth hormone, rhGH) modified with the chelating agent S-2-(4-isothiocyanatobenzyl)-1,4,7-triaz

58 events produced by the translocation of the chelating agent through an alpha-hemolysin pore in the a

59 Furthermore, the amount of the chelating agent used also affects the phase purity and e

60 stability increased to a great extent when a chelating agent was added.

61 : a pore blocking method and a micromolecule-chelating agent within the core.

62 (DOC), -SH (in cysteine, a well-known Ag(+) chelating agent), and -COO (in trolox, a well-known anti

63 By employing a polyhistidine molecule as a chelating agent, and based on the different signatures o

64 l parameters (nonionic and ionic surfactant, chelating agent, bromate, bromide, and pH) led to optima

65 EDTA, a powerful chelating agent, did not have any significant effect on

66 d by treatment of cells with the cholesterol chelating agent, methyl-beta-cyclodextrin, that is thoug

67 ma mandarin fruits was extracted to obtain a chelating agent-soluble pectin fraction (ChSS), a dilute

68 with deferoxamine, a clinically useful iron-chelating agent.

69 e, a target interaction element, and a metal chelating agent.

70 n the perspective of developing bifunctional chelating agents (BCAs), this new synthetic strategy off

71 Chelating agents (EDTA formulations) reduced E. coli CFU

72 ubstantially surpassing conventional Gd(III) chelating agents (r1 approximately 3 mM(-1)s(-1) at 4.7

73 be metal ion-dependent and was inhibited by chelating agents and thus was tentatively proposed to be

74 Strong chelating agents are reported to enhance Cu translocatio

75 Chelating agents can control the speciation and reactivi

76 ical "braking" system was achieved by adding chelating agents capable of sequestering the metal ion e

77 (IV) with Gallocyanin (GC(+)) and glycine as chelating agents in the mixed surfactant media, Polyethy

78 Treatment of DHHC3 with chelating agents in vitro replicated both the specific s

79 arious signaling molecules, transporters and chelating agents of HM metabolism is poorly understood.

80 this system being less influenced by pH and chelating agents present in the extracts.

81 These results demonstrate that iron-chelating agents such as PCIH may be of benefit in the t

82 Currently, chelating agents used in (68)Ga radiopharmaceuticals do

83 to the disease itself, iron overload or the chelating agents used.

84 Rather than using the chelating agents which are commonly used in CPE to form

85 )3](+) core (L8-L10), traditional NxSy-based chelating agents with varying charge and polarity for th

86 Phytosiderophores (PS) are natural chelating agents, exuded by graminaceous plants (grasses

87 application of UV-Fenton processes with two chelating agents, nitrilotriacetic acid (NTA) and [S,S]-

88 lly important molecules through a variety of chelating agents, the choice of which depends upon the i

89 cessible overview of the field of radiometal chelating agents.

90 ic acid, citrate, into the soil rhizosphere, chelating Al(3+) ions and thereby imparting Al-resistanc

91 sed to self-assemble in conjunction with the chelating aldehydes, 4-substituted-2-picolinaldehydes or

92 alyzed hydroacylation of 1,3-dienes with non-chelating aldehydes.

93 Chelating amendments are proposed to enhance Cu phytoext

94 s how the new and rapidly expanding class of chelating ancillary ligands bearing 2,2'-bipyridyl, 1,10

95 Antioxidant, metal-chelating and antifungal activities of all compounds wer

96 nsity lipoprotein (LDL) catalysed by copper (chelating and chain-breaking activity).

97 Chelating and free radicals scavenging activities of ext

98 enging activity, reducing power, ferrous ion-chelating and liposome model system).

99 by X-ray analyses and NMR methods, and both chelating and monodentate binding modes characterised.

100 ers using three model systems (DPPH, ferrous chelating and reducing power).

101 Both the chelating and the indicating nanospheres showed good sel

102 (both protic and aprotic) are bifurcated and chelating, and unlike many molecular liquids a significa

103 ate that holomycin is an intracellular metal-chelating antibiotic that inhibits a subset of metalloen

104 Calprotectin (CP) is a transition metal-chelating antimicrobial protein of the calcium-binding S

105 e installation of other donors as the fourth chelating arm, while avoiding the formation of stereoiso

106 lfur, but also with a neighboring Rh and the chelating aryl carbon of the pincer framework.

107 lts have shown that palladium complexes with chelating aryl- and alkyl-substituted bis-NHC ligands, i

108 talyst based on NiXantphos, a deprotonatable chelating aryldiphosphine ligand, to oxidatively add una

109 or weakly polar sigma-bonds at copper using chelating assistance.

110 involves the installation of a new Si,N-type chelating auxiliary group on the alkene followed by irid

111 The reaction is selective for the chelating azido group, thereby forming monofunctionalize

112 These styrenes are precursors to the chelating benzylidene moiety in a proposed series of nov

113 While chelating binding of the discussed ligands is likely, ex

114 reaction of AlBr3 with 1 molar equiv of the chelating bis(N-heterocyclic carbene) ligand bis(N-Dipp-

115 The first chelating bis(N-heterocyclic silylene)xanthene ligand [S

116 ues were ligated in a stepwise manner with a chelating bis-azide under copper catalysis.

117 The application of acyclic C2-symmetric chelating bis-sulfoxide ligands in the Rh(I)-catalyzed e

118 been prepared from carboxylate ions and the chelating/bridging ligand alpha-methyl-2-pyridine-methan

119 nts with hepatic metastases and flushed with chelating buffer followed by collagenase or mechanical d

120 In live zebrafish, chelating calcium after the first wave, but before the s

121 In cultured DRG neurons, chelating calcium early in the process of WD did not alt

122 rocess of WD did not alter degeneration, but chelating calcium late in WD delayed fragmentation.

123 n spectroscopy (AAS) was used to verify iron chelating capability of nanogels.

124 nversion nanoparticles due to their stronger chelating capability to lanthanides.

125 tal complex stability, we evaluated the zinc-chelating capacity and stability of zinc complexes of wh

126 pectin (>/=58%), probably due to its higher chelating capacity of pro-oxidative metal ions (Fe(2+)),

127 c-binding amino acids but showed higher zinc-chelating capacity than WPH-Pap.

128 and peroxyl radicals, the reducing power and chelating capacity were, in general, in the decreasing o

129 Chelating Capacity) or EECC (EDTA Equivalent Chelating Capacity) indice according to the standard cho

130 g Capacity) and a CECC (Carnosine Equivalent Chelating Capacity) or EECC (EDTA Equivalent Chelating C

131 iciting activities rely on their strong iron-chelating capacity.

132 engineered by means of mussel-inspired metal-chelating catechol-functionalized polymer networks, biol

133 d in Escherichia coli and purified by Nichel-chelating chromatography.

134 for ensuring the effective formation of HMs-chelating complexes that are possibly responsible for th

135 udy, pretreatment with a cell-permeable Ca2+-chelating compound (BAPTA-AM) significantly inhibited AT

136 ylketone thiosemicarbazone Dp44mT is a metal-chelating compound that has been demonstrated to have po

137 This system is evaluated in batch mode via chelating copper at the active site of tyrosinase and in

138 f detection: 0.019microM and 0.008microM for chelating copper at the active site of tyrosinase and th

139 onverting enzyme inhibitor that operates via chelating copper at the active site of tyrosinase and th

140 deficient Arabidopsis plants release Fe(III)-chelating coumarins as part of the strategy I-type Fe ac

141 f the type [Pt(Am)(R(COO)2)2], where Am is a chelating diamine or two monodentate am(m)ine ligands an

142 and exclusively as bis-solvated dimers with chelating diamines.

143 onodentate am(m)ine ligands and R(COO)2 is a chelating dicarboxylato moiety, was synthesized.

144 leptic complexes of the Fe(II) d(6) ion with chelating diimine ligands.

145 3))-H activation, including requirements for chelating directing groups and high reaction temperature

146 lent kappa(2)-H2-H2SiPh2H silyl ligand and a chelating disilane ligand, and both compounds convert to

147 We compared the use of Empore chelating disks and Chelex 100 resin for the selective r

148 However, Empore chelating disks were found to give much higher recoverie

149 Chelating divalent cations from the culture medium aboli

150 Mutations of Fe(II)/NOG-chelating, DNA-interacting, and zinc-chelating residues

151 sely, reducing systemic copper levels with a chelating drug, clinically used to treat copper disorder

152 glucuronoarabinoxylan in presence of calcium chelating EDTA, which would indicate that Xyn30D-CBM35 m

153 ns and thermodynamic integration we show the chelating effect to hold for coupling polymers whose rad

154 razyl (DPPH) radical method, reducing power, chelating effects assay and beta-carotene bleaching.

155 fter appropriate hydrolysis, while metal ion chelating effects were slightly attenuated.

156 be changed by Lewis base displacement of the chelating ethers, with binding equilibria dramatically a

157 These materials can degrade into smaller chelating fragments at rates proportional to the level o

158 phyla of the tested strains and the type of chelating functional groups (i.e., hydroxamate, catechol

159 inhibitors (HDACi) employing different zinc chelating functionalities such as hydroxamic acids and b

160 on in a hexadentate fashion using a new iron-chelating gamma-amino acid.

161 , identifying a calcium ion-binding site and chelating glutamic acid residue that mediate the formati

162 the identified inhibitors, including a metal-chelating group and a charged or polar moiety that could

163 his intermediate, the presence of a suitable chelating group could trigger unexpected aryl-norbornyl

164 extrapolated to substrates bearing a single chelating group, providing further insight into the reac

165 formed exclusively in the absence of this Li-chelating group.

166 Hydroxamic acids are outstanding zinc chelating groups that can be used to design potent and s

167 s as ligands that combine two distinct metal-chelating groups, lipoic acid and imidazole, for the sur

168 olymer with a high density of strong mercury chelating groups.

169 ic repulsions of the anionic ligand with the chelating groups.

170 Metal-chelating heteroaryl small molecules have found widespre

171 ses are involved in the biosynthesis of iron-chelating hydroxamate-containing siderophores that play

172 The two chelating IL systems (one with a pendent polyether chain

173 demonstrating that the pharmacophores of the chelating inhibitors (S)-10a, (R)-10a, and 10b were bind

174 ation mechanism involving the eight-membered chelating intermediate.

175 astrocytic syncytium was loaded with BAPTA (chelating intracellular Ca(2+)) and enhanced when high C

176 tion of calcineurin by TLCS was abolished by chelating intracellular Ca(2+).

177 Chelating ionic liquids (ILs), in which polyether chains

178 actors linked to AD pathogenesis, namely by: chelating iron, copper and zinc; scavenging reactive oxy

179 This article summarizes recent examples of chelating lectin ligands of different size.

180 ted from two epimeric bromides, catalyzed by chelating Lewis acids.

181 its two terminal aryls to afford a bidentate chelating ligand (CN(tBu)Ar3NC) that is able to stabiliz

182 (dppbz)CuH]3 has been prepared by use of the chelating ligand 1,2-bis(diphenylphosphino)benzene (dppb

183 o-Vanillidine-2-amino-p-cresol was used as a chelating ligand and 1-undecanol was selected as an extr

184 onalization based on judicious choice of N,O-chelating ligand and metal center.

185 of the phenyl ring of 2-phenylbenzimidazole chelating ligand of the ruthenium (3a-g) and iridium com

186 anism for homogeneous catalysts in which the chelating ligand plays a key role in facilitating the ca

187 Addition of a chelating ligand that complexes free silver ions indicat

188 lvent, extraction time, concentration of the chelating ligand, salt effect, centrifugation time and s

189 rifluoromethylation of unprotected bidentate chelating ligand, xanthine alkaloids, nucleosides, and r

190 1,3-N,O-Chelating ligands are ubiquitous in nature owing to thei

191 These agents identified as bimetal chelating ligands binding to the active site of the enzy

192 A series of new P^P-chelating ligands constituted by a dicationic -[P(H2Im)2

193 or acids that have bulky or large bite angle chelating ligands deviate the most from this correlation

194 ybrid mesoporous silicas functionalized with chelating ligands for the complexation of heavy metals.

195 Specifically, we focused on the role of iron chelating ligands in promoting chemical oxidation of Fe(

196 unknown organic metal complexes and related chelating ligands in very complex sample matrices using

197 ligand, while use of more common protecting chelating ligands such as ethylenediamine saw a Pd3L2 to

198 Among the range of P,N-chelating ligands that have been employed in asymmetric

199 Due to its chelating ligands, Cr(CN(tBu)Ar3NC)3 is more robust than

200 adding clustering agents, such as calcium or chelating ligands, favor the lateral cis adhesion of the

201 noline), O,O (diketonate), or S,S (dithione) chelating ligands, have been characterized by X-ray crys

202 dened spectra seen with enzymes and strongly chelating ligands.

203 cbl1 plants exudated less Al-chelating malate, accumulated more Al, and displayed a s

204 nd synthesis of potent but nonselective zinc-chelating MMP inhibitors (e.g., 10a and 10b).

205 ne coordination mode, over the typical O,C,C chelating mode for enamides, as the preferred one for th

206 generator radiotherapies is that traditional chelating moieties are unable to sequester the radioacti

207 extrin (beta-CD) and ferrocene (Fc) and iron chelating moieties composed of deferoxamine (DFO) into t

208 This work expands the repertoire of iron-chelating moieties in microbial siderophores.

209 ll-L-serine- (MAS3) and all-D-serine- (mas3) chelating moieties were evaluated in parallel, and a kit

210 olyethylene glycol spacer and a tetrapeptide chelating moiety was found to possess the desired charac

211 Small iron-chelating molecules called siderophores were selected as

212 he RNase H fold with multiple distinctive Zn-chelating motifs and a unique insert, which are predicte

213 to act as a N-donor, as an O-donor, or as a chelating N,O-donor.

214 of the catalyst features the resolution of a chelating N-heterocyclic carbene complex by ligand subst

215 iotics and emphasizes the potential of metal-chelating natural products in antimicrobial therapy.

216 We present the up to now strongest chelating neutral pincer ligand for the simplest electro

217 interaction between the Fe(0) center and the chelating NHC ligand, while the HOMO-1 is associated wit

218 Ni-chelating NLPs (NiNLPs) were assembled to incorporate th

219 The metal-chelating noncanonical amino acid (2,2'-bipyridin-5yl)al

220 n the binding at the first stage of bivalent chelating, not on the binding at the second stage.

221 generated from an acid chloride, the unusual chelating nucleophile (1,8-naphthyridine), and a Lewis a

222 he relationship between the structure of the chelating o-alkoxybenzylidene and the observed initiatio

223 The ratio of bridging oleates to chelating oleates on the surfaces of the QDs is approxim

224 ants, such as betaine and polyols, and metal-chelating organic acids.

225 Previously, we developed a novel metal-chelating packaging film (PP-g-PAA) by grafting acrylic

226 Besides, the detection of metal-chelating peptide is not sensitive enough by spectrophot

227 set up an original method of screening metal chelating peptides in a hydrolysate using Surface Plasmo

228 Iron-chelating peptides were isolated using immobilized metal

229 For the first time, metal chelating peptides were screened in hydrolysates using S

230 t efficacy to selectively separate the metal-chelating peptides.

231 energy structure (3.3 kcal/mol) with two cis-chelating phosphine ligands (41 degrees dihedral angle)

232 operation between iridium(III) and a 1,3-N,O-chelating phosphoramidate ligand has been used to develo

233 s accomplished by using the metallic-complex chelating polymer Mix&Go.

234 ging activity, higher on green tea, and iron chelating potential, higher on L. algarvense.

235 avenging activity and 10-48% for the ferrous-chelating power.

236 strategy that enables to modulate the metal chelating properties of hydroxamic acid groups by bioort

237 toxification mechanisms, we investigated the chelating properties of the protein toward different lig

238 ducing ferric ions and showed the best metal chelating properties.

239 athway with metabolic intermediates of metal-chelating properties.

240 ssociated to the extracted pectin due to its chelating properties.

241 activity in terms of radical scavenging and chelating properties.

242 s effect is fully related to its potent iron-chelating property in the organelle.

243 ting in simultaneously secretion of the iron chelating protein lipocalin 2 (LCN2) and protons, which

244 biological coordination chemistry of Ni(II)-chelating proteins in nature and provide a foundation fo

245 This chelating reaction approach should find useful applicati

246 The metal elements were reacted with the chelating reagent 2,4,6-trimercapto-1,3,5-triazine (TMT)

247 using 1-(2-Pyridylazo)-2-naphthol (PAN) as a chelating reagent and detection by electrothermal atomic

248 s using 2-thenoyltrifluoroacetone (TTA) as a chelating reagent by ETAAS.

249 rom the conjugate, in the presence of strong chelating reagent ethanedithiol.

250 rstly synthesized and characterized as a new chelating reagent for determination of some metals.

251 methyl-beta-cyclodextrin (MbetaCD), a sterol-chelating reagent, causing a 3-fold reduction in total c

252 Diethyl dithiocarbamate was used as chelating reagent.

253 ice were incubated with excess Cu or with Cu-chelating reagents; effects on cell fat content and ATP7

254 II)/NOG-chelating, DNA-interacting, and zinc-chelating residues are frequently observed in human canc

255 regulated by the calmodulin domain's Ca(2+)-chelating residues.

256 ycidyl methacrylate (GMA) based terpolymeric chelating resin was synthesized for the separation and p

257 This chelating resin was used as a new adsorbent material for

258 , volume of the sample and eluent, amount of chelating resin, and interference of ions were examined.

259 Metal ion chelating resin, or the chelators EDTA and desferrioxami

260 A new chelating resin, poly [2-(4-methoxyphenylamino)-2-oxoeth

261 A new chelating resin, poly(N-cyclohexylacrylamide-co-divinylb

262 s and then boiled in the presence of a metal chelating resin.

263 Neither chelating salt produced high levels of soluble protein.

264 m citrate either alone or as part of a mixed chelating salt system resulted in high levels of dispers

265 pite its simplicity, was a good indicator of chelating salt-calcium interactions in rennet casein dis

266 tudy elucidates the critical role of calcium chelating salts in modulating casein hydration and dispe

267 Thus calcium chelating salts may play a more subtle role in modulatin

268 is study investigated the effects of calcium chelating salts on calcium-ion activity (ACa(++)), calci

269 In the absence of calcium chelating salts, these concentrations were significantly

270 reased with increasing concentration of both chelating salts.

271 antly higher for matrices containing calcium chelating salts.

272 ferent in the presence or absence of calcium chelating salts.

273 nufacture of the matrices containing calcium chelating salts; with approximately 23% of total calcium

274 or each type of oxygen-donor present in such chelating (Section 1) or bridging (Section 2) hybrid lig

275 ng copper proteins may possess His-X(aa)-His chelating sequences at their active sites and additional

276 Pathogenic mycobacteria synthesize iron chelating siderophores named mycobactin and carboxymycob

277 e structure of xanthan, which generates more chelating sites at pH 3.5 than at pH 5.5.

278 st-effective material with a high density of chelating sites designed for mercury capture and therefo

279 ude hierarchical porosity, a high density of chelating sites, and the material's robustness, which im

280 nalized with hemilabile ligands of differing chelating strengths, allowing one to assemble them aroun

281 enzenes are very electron-deficient, or when chelating substituents at the ortho position of the aryl

282 he feasibility of highly selective non-metal chelating, substrate-competitive inhibitors of the JmjC

283 parable to, but weaker than, the effect of a chelating synthetic siderophore, DFAM.

284 e, which was further modified with the metal-chelating synthon terpyridine.

285 lent attachment of a paramagnetic lanthanoid chelating tag to the ligand of interest.

286 coiled-coil peptides bearing unnatural metal-chelating terpyridine moieties.

287 through molecular recognition of the ligands chelating the metal ions.

288 BSA reduced AgNP toxicity by chelating the silver ions (Ag(+)) released from the AgNP

289 cal trials evaluating the usefulness of iron-chelating therapy in critical illness and sepsis.

290 ted, of whom 216 (84.7%) were receiving iron-chelating therapy.

291 Esters with a chelating thioether derived from commercially available

292 in which imine acts as a directing group by chelating to the metal center, affords a potential route

293 the catalytically active Zn(2+) ion without chelating to the metal.

294 ts with long-standing disease requiring iron-chelating treatment and a history of splenectomy need re

295 Iron efflux via an iron-chelating tricarboxylic acid cycle intermediate provides

296 very generally entails chemotypes capable of chelating two divalent metal ions in the RNase H active

297 arylbenzazole moiety for Abeta binding and a chelating unit for metal ions coordination for instance.

298 on the length of linker connecting the metal chelating unit to the hydroxyl group.

299 ng within the MMP-13 active site, the Zn(2+) chelating unit was replaced with nonchelating polar resi

300 rotein that exerts antimicrobial activity by chelating zinc and manganese.