ライフサイエンスコーパス: chemokine

1 ntirely dispensable for scavenging of either chemokine.

2 d gene induction of CXCL5, a proinflammatory chemokine.

3 nalizes and degrades most proinflammatory CC-chemokines.

4 onse by secreting inflammatory cytokines and chemokines.

5 f ELNs are needed for interrogation of these chemokines.

6 strated by a family of small proteins called chemokines.

7 f IFN-gamma and regulatory T cell-recruiting chemokines.

8 nt and decreased production of cytokines and chemokines.

9 induction of pro-inflammatory cytokines and chemokines.

10 oglial NF-kappaB activation and secretion of chemokines.

11 invasion, all of which involve the action of chemokines.

12 to produce large quantities of cytokines and chemokines.

13 tes exhibited high-affinity binding to human chemokines.

14 cretion of inflammatory cytokines as well as chemokines.

15 t increases in proinflammatory cytokines and chemokines.

16 of sterile inflammation, such as C-X-C motif chemokine 1, C-X-C motif chemokine 2, and C-X-C motif ch

17 1, C-X-C motif chemokine 2, and C-X-C motif chemokine 10, in parallel with depression of serum marke

18 such as C-X-C motif chemokine 1, C-X-C motif chemokine 2, and C-X-C motif chemokine 10, in parallel w

19 Targeting six chemokine 3'-UTRs increased chemokine mRNA levels as exp

20 vation, such as CCL5, CCL11, and C-X-C motif chemokine 5.

21 monstrate prolonged expression of neutrophil chemokines, a concomitant extended increase in the accum

22 CXCL4 is a chemokine abundantly produced by activated platelets and

23 kine (C-X-C motif) ligand (CXCL) 1 and CXCL2 chemokines, activated inflammatory macrophages, and elev

24 Activating transcription factor 3 attenuates chemokine and cytokine expression in mouse skeletal musc

25 eloid DCs (mDCs) was necessary for increased chemokine and IFN-alpha secretion in response to the par

26 alters epithelial secretion of a neutrophil chemokine and slows wound closure in HBE cells.

27 The CXCR4 chemokine and Sonic Hedgehog (SHH) morphogen pathways ar

28 MLN4924 further attenuated the expression of chemokines and adhesion molecules in endothelial cells a

29 al level and TNF-alpha-induced expression of chemokines and adhesion molecules, including VCAM-1, IL-

30 h PFSnet subnetwork revealed upregulation of chemokines and axonal permissive factors including FGF2,

31 Cytokine/chemokines and cellular reponses provided insight into t

32 Chemokines and chemokine receptors have rapidly diversif

33 functions, including cleaving and activating chemokines and controlling cell survival and proliferati

34 an alarmin linked to necroptosis, and other chemokines and cytokines and prevented macrophage infilt

35 clerosis is regulated by adhesion molecules, chemokines and cytokines.

36 e fluid and lower expression of inflammatory chemokines and cytokines.

37 LPS-induced expression of many cytokines and chemokines and in modulating Rab7B and P2RX7 expression

38 jective of this study was to investigate CXC chemokines and its receptor in patients with Behcet's di

39 II, cells undergoing necroptosis can express chemokines and other regulatory molecules and promote an

40 eudotuberculosis resistance to antimicrobial chemokines and survival during mouse infections.

41 Chemokines and their cell surface G protein-coupled rece

42 and provide the first evidence of a role for chemokines and their receptors in postnatal development

43 attract neutrophils and monocytes, to induce chemokines and to stimulate downstream ERK signaling in

44 Tbx21, Gzmb and genes encoding cytokines and chemokines, and genes controlling glycolysis.

45 e an increased ability to produce cytokines, chemokines, and lipid mediators in response to subsequen

46 ells to support the production of cytokines, chemokines, and other factors important in the developme

47 ated expression of proinflammatory cytokines/chemokines, and significantly alleviated post-ischemic e

48 l or stability of pro-inflammatory cytokines/chemokines are abolished by PARP1 ablation or inhibition

49 droplets of agarose gel containing different chemokines are applied onto the surface of a Petri dish,

50 inflammatory process in periodontal disease, chemokines are upregulated to promote recruitment of inf

51 re recruited to the lung through a CCL2-CCR2 chemokine axis and by IL-13 expressing innate lymphoid c

52 essor cell (MDSC) infiltration in tumors via chemokine axis.

53 We conclude that chemokine-binding evasin proteins are widely expressed a

54 omitant decrease in circulating inflammatory chemokines, blunted antiviral gene signature within the

55 restores lymphocyte migration in response to chemokines, both in vitro and in vivo.

56 is classically defined as a proinflammatory chemokine, but its role in chronic inflammatory diseases

57 ors, including the monocyte chemoattractant, chemokine (C-C motif) ligand (CCL) 2, and the innate imm

58 ion and proliferation of tumor cells through chemokine (C-C motif) ligand 2 (CCL-2)-dependent recruit

59 and increased colonic TNF-alpha, CXCL10, and chemokine (C-C motif) ligand 2 (CCL2) mRNA expression.

60 Recombinant IL-17A induced expression of chemokine (C-C motif) ligand 2 in neonatal cholangiocyte

61 elease of proinflammatory cytokines, such as chemokine (C-C motif) ligand 5 (P < 0.01) and granulocyt

62 IL-6, tumor necrosis factor-alpha, IL-1beta, chemokine (C-C motif) ligands 2 and 3, macrophage inhibi

63 in vitro, and blockade of the corresponding chemokine (C-C motif) receptor 2 reduced recruitment of

64 on with neutrophils, increased expression of chemokine (C-X-C motif) ligand (CXCL) 1 and CXCL2 chemok

65 Chemokine (C-X-C motif) ligand 9 (CXCL9) levels above th

66 be part of a growing family of cytokines and chemokines, called kinocidins, that also have antimicrob

67 ve the translational silencing of a group of chemokine (CC/CXC) and chemokine receptor (CCR) mRNAs, t

68 with intrapulmonary HCMV replication for the chemokines CCL-18 and CCL-20.

69 um significantly increased production of two chemokines, CCL14 and CXCL6.

70 blastic stromal cells that were derived from chemokine Ccl19-expressing host cells, including fibrobl

71 found that stable gradients of intermediate chemokines (CCL19 and CXCL12) failed to promote persiste

72 ukin-1beta, tumor necrosis factor-alpha, the chemokine CCL2, and interferon regulatory factor-5 (IRF5

73 macrophages, inducing the production of the chemokine CCL2, which in turn recruited circulating CCR2

74 ably, cytokines IL-6, TNF, and IFN-gamma and chemokines CCL2, CCL3, and CCL4 have been associated wit

75 biological properties of the prototypical CC chemokine, CCL2.

76 Of interest, we found that expression of 2 chemokines, CCL2 and CXCL10, correlated with the median

77 toward higher concentrations of immobilized chemokine CCL21.

78 alysis revealed that MK2 signaling regulated chemokines CCL3 and CCL4 in murine calvarial tissue.

79 Chemokines Ccl5 and Ccl8 were persistently elevated in i

80 ing that only cells that express the cognate chemokine cell surface receptor, migrate under the spot

81 er than the type of inflammation, making the chemokine/chemokine receptor system a key point of the i

82 Higher levels of these chemokines coincided with prominent infiltration of the

83 D2, and eosinophil and T-helper type 2 cell chemokines compared with healthy subjects.

84 Instead, rising chemokine concentrations were needed, implying that temp

85 Chemokine-controlled NADPH oxidases and metabolically co

86 new treatments, and skin expression of these chemokines could be used to monitor disease activity and

87 We found that the chemokine CX3CL1 was upregulated in both human and murin

88 Here, we explored whether the level of the chemokine CXCL-10, in combination with findings of molec

89 or cells constitutively produced the ELC-CXC chemokine CXCL-8 (IL8), enabling them to recruit APRIL-p

90 ncer Genome Atlas showed that the neutrophil chemokine CXCL1 gene was highly upregulated in colon tum

91 In addition, the chemokines CXCL1, CXCL5, CXCL6, and complement C3, known

92 otropic TG delivery of the T cell-attracting chemokine CXCL10 (pull), boosted the number and function

93 dition, the metastatic IECs also induced the chemokine CXCL10 in a TLR3-, TRIF-, and IRF3-dependent m

94 on of the transcription factor IRF1, and the chemokine, CXCL10.

95 by binding, internalizing, and degrading the chemokines CXCL11 and CXCL12 to shape and terminate chem

96 Here we show a peculiar role for the chemokine CXCL12 secreted in early PDAC and for its rece

97 polarization, and reduced expression of the chemokine Cxcl12 Under shear stress in culture, Dach1 ov

98 s CXCR7, binds and degrades the constitutive chemokine CXCL12, which also binds the canonical recepto

99 The chemokine CXCL13 is expressed by FDC and follicular stro

100 The chemokine CXCL13 recruits both Tfh and B cells, which is

101 ermethylation leads to downregulation of the chemokine CXCL14 and suppression of antitumor immune res

102 Epithelial chemokine CXCL14 synergizes with CXCL12 via allosteric m

103 Here, we show that the chemokine cxcl8 and its receptor, cxcr1, are expressed b

104 reased expression of the IFN-gamma-inducible chemokines Cxcl9 and Cxcl10 in the liver and spleen, as

105 ulating SDF-1 and the second receptor of the chemokine (CXCR4) expression.

106 with previous polypharmacological studies on chemokine/cytokine release from human macrophages, the p

107 Similar to ECM proteins, matrix-bound chemokines, cytokines, and growth factors (GFs) influenc

108 dramatic increase in mRNAs encoding various chemokines, cytokines, growth factors, and angiogenesis

109 sults for the L. donovani-infected livers of chemokine-deficient mice (CXCR6(-/-) mice were used as C

110 acellular receptor transport is required for chemokine degradation.

111 al parameters such as receptor transport and chemokine degradation.

112 cted ligand specificity in the mechanisms of chemokine degradation.

113 and-specific conformational transitions with chemokine-dependent receptor transport dynamics and poin

114 its ability to accurately predict intranodal chemokine distribution.

115 n atypical structure consisting of a classic chemokine domain N-terminal to a second unique domain, r

116 ent advances that illuminate the dynamics of chemokine-driven thymocyte migration, localization, and

117 All other chemokines examined did not reveal significant differenc

118 iated downregulation of granulocyte-specific chemokine expression in CAF, which limited migration of

119 Lastly, we showed that increased chemokine expression in FIP200-null NSCs was induced by

120 an inhibitor of proinflammatory cytokine and chemokine expression in intrarenal macrophages.

121 Analysis of chemokine expression in mouse skin showed that CXCL9 and

122 ction with reduced bacterial load, decreased chemokine expression, and reduced inflammation in the lu

123 nsive genes related to antigen presentation, chemokine expression, cytotoxic activity, and adaptive i

124 parasites overexpressing EhMIF had increased chemokine expression, neutrophil influx, and mucosal dam

125 ed MIP-2 (macrophage inflammatory protein-2) chemokine expression, which was reduced in CVB3 S100A8 k

126 (apoptosis), neutrophil influx and cytokine/chemokine expression.

127 We show that the chemokine fractalkine (CX3CL1), an activating ligand of

128 cant transient upregulation of cytokines and chemokines from tracheal epithelial cells (TECs) in vitr

129 suppression of pro-inflammatory cytokine and chemokine gene expression, consistent with an anti-infla

130 beta, IFN-lambda1, and interferon-stimulated chemokine gene expression.

131 nherent ability of macrophages to respond to chemokine gradients was supported by Western blotting.

132 eded with endothelial cells and subjected to chemokine gradients within a microfluidic device.

133 omputational model to investigate intranodal chemokine gradients.

134 indicated that individual IFN-gamma-induced chemokines have diverse affects and (i) may be entirely

135 tiligo, and we found that the epidermis is a chemokine-high niche in both a mouse model and human vit

136 d CD69 and down-regulated macrophage-derived chemokine, human leukocyte antigen DR, CD86, and CD80 co

137 igh levels of pro-inflammatory cytokines and chemokines (IL-6, IFN-gamma, TNF-alpha, CXCL1, and CCL2)

138 found that MSC-produced CXCL12, an important chemokine in tumour metastasis, was markedly inhibited b

139 Here, we analyzed cytokines and chemokines in blister fluids of patients affected by dys

140 NA expression of some macrophage markers and chemokines in liver and VAT of HFD-fed M-JAK2(-/-) mice.

141 tic islets produce and secrete cytokines and chemokines in response to inflammatory and metabolic str

142 hi augmented the expression of cytokines and chemokines in response to sequential challenges with LPS

143 th scavenging; although Q301E(7.39) degraded chemokines in the absence of arrestin, S103D(2.63) had r

144 ted with a significant increase of cytokines/chemokines in the brain, including interleukin-1beta, in

145 e report altered expression of cytokines and chemokines in the cerebellum of MIA offspring, including

146 ls infiltration and release of cytokines and chemokines in the lungs, which were significantly attenu

147 Highly sensitive detection of chemokines in various biological matrices and its intera

148 d stimulated the expression of cytokines and chemokines in WT and TLR4-KO HSCs.

149 mRNA and protein expression of cytokines and chemokines in WT and TLR4-KO mice.

150 yte-associated genes and IFN-gamma-inducible chemokines, including CXCL10, in IDH-mutated (IDH-MUT) t

151 ins counterregulate the release of cytokines/chemokines, including TNFalpha, IL-6, IL-8, CCL4, and CC

152 In controls, no such chemokine increase was observed.

153 ly by selectins, cell adhesion molecules and chemokines induced by pro-inflammatory cytokines such as

154 ule of integrin affinity triggering mediates chemokine-induced leukocyte adhesion.

155 ted T cells, inhibiting their spontaneous or chemokine-induced migration.

156 he three GEFs are all critically involved in chemokine-induced RhoA and Rac1 activation, thus suggest

157 sis preceding neutrophil influx and cytokine/chemokine induction during active menstruation.

158 ripheral and central nervous system cytokine/chemokine inflammatory responses.

159 erent physicochemical challenges of receptor:chemokine interfaces, and suggest novel epitopes that ca

160 nking JAKs to rho small GTPase activation by chemokines is still incompletely described.

161 ue to diminished local inflammatory cytokine/chemokine levels and neutrophil recruitment to the kidne

162 o significant differences in CSF cytokine or chemokine levels between cases and controls.

163 , and higher brain inflammatory cytokine and chemokine levels than control C57BL/6J mice.

164 Serum cytokine and chemokine levels were measured at baseline and after BV.

165 d immature myeloid cell infiltrate and blood chemokine levels.

166 ine receptor 4 (CXCR4), is selective for CXC chemokine ligand 12 (CXCL12), is broadly expressed in bl

167 Binding of its ligand, C-X-C chemokine ligand 12 (CXCL12), results in receptor intern

168 nd 8, and monocyte chemoattractant protein-1/chemokine ligand 2 in the MSC secretome and improved MSC

169 CC chemokine ligand 20 induction by tumor necrosis factor-a

170 peptidase inhibitor, clade H (SERPINH1) and chemokine ligand 4 (CCL4), while exploratory gene ontolo

171 erleukins 1beta and 6, and cysteine-cysteine chemokine ligand 5 [CCL5]) and profibrogenic (transformi

172 n Trim32-deficient keratinocytes, whereas CC chemokine ligand 5 induction by tumor necrosis factor-al

173 of interleukin-6, interleukin-8/C-X-C motif chemokine ligand 8, and monocyte chemoattractant protein

174 under the spot containing its corresponding chemokine ligand.

175 They also efficiently scavenge their chemokine ligands, thereby contributing to gradient main

176 nize the more abundant GAG-bound form of the chemokine may not be the optimal strategy to achieve dis

177 The CC chemokine MCK-2 encoded by mouse CMV (MCMV) has an atypi

178 ated chemokine (TARC) and macrophage-derived chemokine (MDC)), CD (10 proteins), and PS (kynureninase

179 r plasma levels of 38 inflammatory cytokines/chemokines measured using multiplex immunoassays.

180 Overall, our results showed that chemokine-mediated recruitment of neutrophils secreting

181 s 2 and 3, macrophage inhibitory factor, and chemokines mediating neutrophil and monocyte infiltratio

182 m of ligands, including synthetic compounds, chemokines, mitogens, fatty acids, and hormones.

183 We have previously shown that the chemokine, monocyte chemoattractant protein-1 (MCP-1), i

184 Human endometrial and mouse uterine cytokine/chemokine mRNA concentrations were significantly increas

185 Targeting six chemokine 3'-UTRs increased chemokine mRNA levels as expected.

186 The increase in cytokines/chemokines of hepatic injury was much higher in ConA-tre

187 The chemokine pathway, in turn, directs the posterior outgro

188 rospinal fluid (CSF) levels of cytokines and chemokines predicted C-IRIS and are potential predictive

189 f Cancer Cell, Spranger et al. indicate that chemokines produced by intratumoral Batf3 dendritic cell

190 sed not only the number of degranulating and chemokine-producing mast cells but also the magnitude of

191 NA restored fluticasone repressive action on chemokine production and its ability to induce GRalpha n

192 , poly(I.C)-induced neutrophilia and mucosal chemokine production are blocked by a small-molecule BRD

193 nitude is sensitive to these key parameters: chemokine production, diffusivity, matrix binding site a

194 de of individual mast cell degranulation and chemokine production.

195 tes and down regulated tumor-promoting cyto-/chemokine profile in bronchoalveolar lavage fluid, decre

196 Ct infection altered the chemokine profile of decidualised ESC as shown by proteo

197 vestigated the role of prenatal cytokine and chemokine profiles on neurodevelopmental outcomes in hum

198 Chemokines promote leukocyte recruitment during inflamma

199 g with profound suppression of CCL2 and CCL7 chemokines, providing evidence for roles of MARCO in act

200 lencing of a group of chemokine (CC/CXC) and chemokine receptor (CCR) mRNAs, thereby helping to resol

201 t rs2814778(G) of the gene encoding atypical chemokine receptor 1 (ACKR1).

202 n vasculature where they reside through CX3C-chemokine receptor 1 (CX3CR1)-dependent adherence.

203 membrane-bound psoriasis-associated atypical chemokine receptor 2 (ACKR2) binds, internalizes and deg

204 mation through activation of endothelial CXC Chemokine Receptor 2 (CXCR2) and production of endotheli

205 rapidly mobilized upon inflammation in a CC-chemokine receptor 2-dependent manner, and the nonclassi

206 Lymphocytes expressing C-X-C chemokine receptor 3 CD8 significantly correlated with O

207 ve hypoxia-induced expression of C-X-C motif chemokine receptor 4 (CXCR4) on invading tumor cells, ma

208 The CXC-motif chemokine receptor 4 (CXCR4) represents a promising targ

209 The chemokine receptor, CXC chemokine receptor 4 (CXCR4), is selective for CXC chemo

210 stromal cell-derived factor-1 (SDF-1)/C-X-C chemokine receptor 4 axis, in the development of those l

211 dified unselected CD8 T cells to express CXC chemokine receptor 5 (CXCR5), the chemokine receptor imp

212 The atypical chemokine receptor ACKR3 contributes to chemotaxis by bi

213 xpression of immune-related pathways such as chemokine receptor activity, chemotaxis and cytokine bio

214 Differences in the chemokine receptor and beta1 integrin expression profile

215 erapies and point to a multifaceted role for chemokine receptor binding in promoting HIV-1 entry.

216 FI-binding affinity and the stoichiometry of chemokine receptor binding to trimeric Env.

217 s and models promote unique understanding of chemokine receptor biology, including the interpretation

218 Elevated expression of the chemokine receptor CCR4 in tumors is associated with poo

219 The chemokine receptor CCR7 drives leukocyte migration into

220 from brain parenchyma is dependent upon the chemokine receptor CCR7.

221 ligand discovery and design studies based on chemokine receptor crystal structures and homology model

222 Interaction between the chemokine receptor CXCR4 and its chief ligand CXCL12 pla

223 s that focal adhesion kinase-1 (FAK) and the chemokine receptor CXCR4 promote epithelial repair mecha

224 tor S1PR5 on NK cells, and expression of the chemokine receptor CXCR4 were all required for NK cell l

225 The recently discovered chemokine receptor CXCR7 and its ligand stromal cell-der

226 The atypical chemokine receptor D6/ACKR2 is expressed on apoptotic PM

227 rization of MR1T cell clones showed multiple chemokine receptor expression profiles and secretion of

228 xpress CXC chemokine receptor 5 (CXCR5), the chemokine receptor implicated in cellular entry into B-c

229 We emphasize the role of cholesterol in chemokine receptor oligomerization, thereby promoting th

230 Interestingly, TKIs modulated the chemokine receptor repertoire of immune cells.

231 ss CXCR5 (C-X-C chemokine receptor type 5, a chemokine receptor required for homing to GCs) and expan

232 chestrating cell migration, it is vital that chemokine receptor signaling is tightly regulated to ens

233 membrane bilayer, and consequently can tune chemokine receptor signaling.

234 In parallel, chemokine receptor structures with small molecules revea

235 c ablation or pharmacologic inhibition of CC chemokine receptor type 2 (CCR2) reduced macrophage (MP)

236 The generated MDSC were expressed C-C chemokine receptor type 2 (CCR2), which was enhanced by

237 ajor histocompatibility complex II/C-C motif chemokine receptor type 2) macrophages expressed higher

238 V)-specific CD8 T cells express CXCR5 (C-X-C chemokine receptor type 5, a chemokine receptor required

239 CCR5 is the primary chemokine receptor utilized by HIV to infect leukocytes,

240 ecific small molecule antagonist of the CCR6 chemokine receptor, CCX2553, was efficacious in reducing

241 The chemokine receptor, CXC chemokine receptor 4 (CXCR4), is

242 tic deletion of CX3CR1, a microglia-specific chemokine receptor, promotes recovery after traumatic sp

243 cilitates the prediction of the structure of chemokine receptor-ligand complexes that have not been c

244 nce for epigenetic regulation of an atypical chemokine receptor.

245 in melanoma microenvironment is supported by chemokine receptor/chemokine signaling.

246 nal similarities with the family of atypical chemokine receptors (ACKRs).

247 While several chemokine receptors and ligands control multiple stages

248 Atypical chemokine receptors do not mediate chemotaxis or G prote

249 Chemokines and chemokine receptors have rapidly diversified in teleost

250 Cells expressing the corresponding cognate chemokine receptors migrate against this gradient by cra

251 f T cells from the blood involves the use of chemokine receptors on the T-cell surface and chemokines

252 detailed analysis of activation markers and chemokine receptors was performed on IgG4-expressing B c

253 integration of new structural information on chemokine receptors with extensive structure-activity re

254 -associated surface markers, interleukin-10, chemokine receptors, and immunoglobulin heavy-chain isot

255 We found that two chemokine receptors, CXCR3 and CCR10, are upregulated on

256 inhibitory receptors, reduced expression of chemokine receptors, proliferated less, and produced les

257 ies and challenges to find novel ligands for chemokine receptors.

258 occupancy as a key parameter when targeting chemokine receptors.

259 rated that pathways related to cytokine- and chemokine-related pathways but also osteoclast different

260 on of ESC impairs decidualisation and alters chemokine release.

261 h altered local proinflammatory cytokine and chemokine responses and differential infiltration of mye

262 4 synergized with CXCL12 in the induction of chemokine responses in primary human lymphoid cells and

263 Stress-evoked cytokine/chemokine responses, or sterile inflammation, can facili

264 In particular, we analyzed whether these chemokines rise in the allograft and/or the blood and ar

265 ned the first bifunctional nanobiosensor for chemokine screening and detection in a single experiment

266 sity to metastasize early into intratumoral, chemokine-secreting nerves.

267 ule release, and more sustained cytokine and chemokine secretion than "ineffective" CD8(+) T-cell clo

268 tional regulation of components of the Cxcr4-chemokine signaling pathway.

269 , and DOCK2 are tyrosine phosphorylated upon chemokine signaling with timing coherent with rapid LFA-

270 recent advances regarding the specificity of chemokine signaling, and novel techniques for evaluating

271 d with this analysis including, cytokine and chemokine signaling, nucleotide-binding oligomerization

272 vironment is supported by chemokine receptor/chemokine signaling.

273 f a SOS1 specificity shift in the context of chemokine signaling.

274 ites of infection are driven by cytokine and chemokine signals that directly target neutrophils via s

275 We show that this migration is chemokine-specific; meaning that only cells that express

276 t structural plasticity facilitates receptor-chemokine specificity and enables exploitation by HIV, a

277 stream from <em>CXCL12</em>, which encodes a chemokine, stromal cell-derived factor 1, that is expres

278 ery rate < 0.05), including IFNG, TNF, CSF2, chemokines, such as CCL3, CCL4, and XCL1, and modulators

279 in E (IgE), thymus- and activation-regulated chemokine (TARC) and macrophage-derived chemokine (MDC))

280 Fractalkine (CX3 CL1), a chemokine that regulates adhesion and migration of leuko

281 hemokine receptors on the T-cell surface and chemokines that are present in infected tissue.

282 ment of the DR, with subsequent induction of chemokines that drive HSC recruitment in CFLD.

283 MCMV infection increased the expression of chemokines that interact with the receptors CXCR3 and CC

284 ction, instructs epithelial cells to produce chemokines that localize monocyte-derived mononuclear ph

285 es increased the expression of cytokines and chemokines that regulate inflammatory influx to sites of

286 corded with IL-15 receptors, APOBEC3G and CC chemokines, the latter downmodulating CCR5 molecules.

287 d secretion of proinflammatory cytokines and chemokines, the senescence-associated secretory phenotyp

288 proteins named "evasins," which bind to host chemokines, thereby inhibiting the recruitment of leukoc

289 oteins but also by controlling the influx of chemokines through the regulation and shedding of syndec

290 levels of pulmonary and activation-regulated chemokine, tissue inhibitor of metalloproteinases 1, and

291 s depends on IFN-gamma and IFN-gamma-induced chemokines to promote T-cell recruitment to the epidermi

292 ier groundwork exploring the contribution of chemokines to T cell development, recent advances regard

293 ected pre-ART were assayed for cytokines and chemokines using a 17-plex Luminex kit or enzyme-linked

294 , B cells, and NK cells, with 49 recombinant chemokines using a singular technique, and standardized

295 The nitrated chemokine was unable to induce transendothelial monocyte

296 Levels of cytokines and chemokines were compared between groups using multivaria

297 d mice; hepatic histopathology and cytokines/chemokines were determined after 6 hours.

298 Levels of IFN-gamma and IFN-gamma-inducible chemokines were evaluated by using real-time PCR in the

299 Six cytokines/chemokines were quantified by multiplex immunoassay, alv

300 uding AST, ALT, and a panel of cytokines and chemokines, were examined.

301 We therefore concluded that targeting chemokines with antibodies such as 1B6 that recognize th