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1 d the confounding impact of radiotherapy and chemoradiation.
2 ncer when given as maintenance therapy after chemoradiation.
3 s were obtained before and after neoadjuvant chemoradiation.
4 eal squamous cell carcinoma (ESCC) receiving chemoradiation.
5 duction is related to clinical outcome after chemoradiation.
6 ents (total, 220) undergoing chemotherapy or chemoradiation.
7 Subsequently, patients received 5-FU based chemoradiation.
8 after cediranib treatment, unlike that after chemoradiation.
9 ancer patients with a pCR after preoperative chemoradiation.
10 r patients with a pCR following preoperative chemoradiation.
11 onse 3 mo after the completion of concurrent chemoradiation.
12 prior to definitive radiation or concurrent chemoradiation.
13 g interferon-alpha with 5-fluorouracil-based chemoradiation.
14 patients; 79 patients (88%) completed chemo-chemoradiation.
15 with rectal cancer treated with preoperative chemoradiation.
16 aluation of patients for esophagectomy after chemoradiation.
17 problems with re-staging rectal cancer after chemoradiation.
18 in those demonstrating objective response to chemoradiation.
19 18 months among patients given neo-adjuvant chemoradiation.
20 of cisplatin administered during concurrent chemoradiation.
21 e of the situation in vivo during concurrent chemoradiation.
22 timized with the use of concurrent and early chemoradiation.
23 nts had a complete response after concurrent chemoradiation.
24 complete pathologic response to preoperative chemoradiation.
25 resection and adjuvant chemotherapy but not chemoradiation.
26 s performed 4 to 8 weeks after completion of chemoradiation.
27 r of the esophagus treated with preoperative chemoradiation.
28 esophageal carcinoma treated primarily with chemoradiation.
29 were given every 4 weeks after completion of chemoradiation.
30 inoma benefit significantly from neoadjuvant chemoradiation.
31 en in the subgroup that received neoadjuvant chemoradiation.
32 o demonstrate survival benefit from adjuvant chemoradiation.
33 t consisting of transurethral resection with chemoradiation.
34 jected to curable treatment with surgery and chemoradiation.
35 n patients with NSCLC treated by concomitant chemoradiation.
36 ade 3-4 haematological adverse events during chemoradiation.
37 ad total mesorectal excision 6-8 weeks after chemoradiation.
38 d disease, which include chemotherapy and/or chemoradiation.
40 nificant increase in the use of preoperative chemoradiation (1% versus 42%, P < 0.001) in the histori
42 histology (69% vs. 86%); use of neoadjuvant chemoradiation (28% vs. 52%); mean blood loss (677 vs. 3
43 ll or adenocarcinoma and planned neoadjuvant chemoradiation (5- fluorouracil, cisplatin, 40Gy) follow
44 onsecutive patients who received neoadjuvant chemoradiation (5-fluorouracil +/- cisplatin and 4,500-5
45 py, 51% v 71%, respectively; P = .038; after chemoradiation, 75% v 93%, respectively; P = .028) and O
46 n the selection of patients for preoperative chemoradiation, a strategy proven to improve outcomes in
47 without concurrent chemotherapy, or primary chemoradiation according to initial nodal disease burden
50 ance; Phase III Intergroup Trial of Adjuvant Chemoradiation After Resection of Gastric or Gastroesoph
51 carcinoma, previously randomized to adjuvant chemoradiation after surgery or surgery alone, to measur
52 systemic chemotherapy alone (n = 38; 6.5%), chemoradiation alone (n = 261; 44.8%), or both (n = 284;
54 parable survival has been demonstrated using chemoradiation alone, leading to the hypothesis that sur
59 h esophageal cancer treated with neoadjuvant chemoradiation and esophagectomy in the National Cancer
60 adjuvant chemotherapy (AC) after neoadjuvant chemoradiation and esophagectomy is associated with impr
63 peutic options will increase the efficacy of chemoradiation and improved the survival of these patien
64 ed by a significant response to preoperative chemoradiation and intersphincteric resection, without c
66 ellent single-center outcomes of neoadjuvant chemoradiation and liver transplantation for unresectabl
67 rentiated tumors evidencing less response to chemoradiation and more likely to require extended resec
68 fter, a novel protocol combining neoadjuvant chemoradiation and orthotopic liver transplantation was
70 who received preoperative gemcitabine-based chemoradiation and pancreaticoduodenectomy (PD) for stag
71 A recent multicenter study of preoperative chemoradiation and pancreaticoduodenectomy for localized
72 n anoscopy-guided ablation) and anal cancer (chemoradiation and possibly intensity-modulated radiatio
73 ss whether adding cycles of mFOLFOX6 between chemoradiation and surgery increased the proportion of p
74 s with rectal cancers underwent preoperative chemoradiation and surgical resection for curative inten
75 -related complications were evaluated during chemoradiation and the immediate 3- to 4-week postchemor
76 from the anal verge, treated by preoperative chemoradiation and total mesorectal excision from 1998 t
78 t restaging 4 to 6 weeks after completion of chemoradiation and, in the absence of disease progressio
79 nse at 26 weeks and acute toxic effects (for chemoradiation), and progression-free survival (for main
80 c restaging was performed 4 to 7 weeks after chemoradiation, and patients with localized disease unde
81 c restaging was performed 4 to 8 weeks after chemoradiation, and patients with localized disease unde
82 c restaging was performed 4 to 6 weeks after chemoradiation, and patients with localized disease unde
86 native chemotherapy regimens and neoadjuvant chemoradiation are being investigated to improve outcome
87 y strategies incorporating radiation or even chemoradiation are frequently considered in some cases.
88 either surgery alone (arm I) or preoperative chemoradiation (arm II) with cisplatin 20 mg/m2/d on day
90 herapy alone, firmly establishing concurrent chemoradiation as the standard of care in locally advanc
91 copic biopsies can predict minor response to chemoradiation, as a basis for individualized therapy of
97 disease (MRD; enhancing tumour <2 cm(2) post-chemoradiation by central review), analysed by modified
99 is unlikely to be beneficial, but definitive chemoradiation can produce significant 5-year survival r
101 in Carcinoma of the Anal Canal], concurrent chemoradiation (CCR) with fluorouracil (FU) plus mitomyc
106 as divided into five phases: preirradiation, chemoradiation, consolidation, maintenance, and continua
107 The Timing of Rectal Cancer Response to Chemoradiation Consortium designed a prospective, multic
108 The identification of patients with a pCR to chemoradiation could potentially spare those patients th
109 rates after sphincter-preserving definitive chemoradiation (CRT) and is typically associated with an
112 shown resistance to conventional concurrent chemoradiation (CRT) therapy and carries a relatively po
113 egional failure (LRF) rates after definitive chemoradiation (CRT), associated with anogenital human p
116 inical and radiologic imaging response after chemoradiation do not require elective neck dissection.
117 l-based study, the addition of postoperative chemoradiation (either sequentially or concomitantly) af
121 local excision alone for very early tumors, chemoradiation followed by either local excision of a sm
123 stal rectal cancer treated with preoperative chemoradiation followed by low anterior resection (LAR)/
125 ded into 2 treatment groups: (1) neoadjuvant chemoradiation followed by surgery and (2) surgery alone
126 identified, of whom 539 received neoadjuvant chemoradiation followed by surgery and 770 received surg
127 The 3-year OS was better for neoadjuvant chemoradiation followed by surgery compared with surgery
130 Patients without response to neoadjuvant chemoradiation for esophageal cancer have no prognostic
132 eatment is palliative, although fluorouracil chemoradiation for locally advanced and gemcitabine chem
133 review of 27 patients undergoing concurrent chemoradiation for locally advanced laryngeal cancers (8
134 review of 33 patients undergoing concurrent chemoradiation for locally advanced oropharyngeal cancer
135 is morbidity on the delivery of preoperative chemoradiation for pancreatic cancer at a tertiary care
137 and the addition of cetuximab to concurrent chemoradiation for patients with inoperable stage III no
139 lusion Although the addition of cetuximab to chemoradiation for SCCAC was associated with lower LRF r
142 d to improve the reporting of RCTs examining chemoradiation for treatment of patients with squamous c
143 ndomised controlled trials (RCTs) of radical chemoradiation for treatment of squamous cell carcinoma
144 stage II/III NSCLC treated definitively with chemoradiation from June 1992 to June 1998 at the Univer
145 ne and cisplatin chemotherapy in addition to chemoradiation (Gem-Cis-XRT) and pancreaticoduodenectomy
153 s, here we report that CC CSCs, which resist chemoradiation, have higher SUMO activating enzyme (E1)
154 er for cN+ patients who received neoadjuvant chemoradiation (hazard ratio, 0.52; 95% CI, 0.42-0.66; P
155 95% CI: 1.15-2.66, P = 0.009), and adjuvant chemoradiation (HR: 0.57, 95% CI: 0.42-0.78, P < 0.0001)
156 hemotherapy or postoperative chemotherapy or chemoradiation improves outcomes relative to surgery alo
158 hether replacing mitomycin with cisplatin in chemoradiation improves response, and whether maintenanc
159 was undertaken to determine whether adjuvant chemoradiation improves survival compared with surgery a
161 water ADC before and after chemotherapy and chemoradiation in 14 patients with locally advanced rect
162 mly assigned patients with progression after chemoradiation in a 2:1 ratio to receive lomustine plus
164 ith resistance to cytotoxic chemotherapy and chemoradiation in an understudied phenomenon known as hy
165 table perihilar CCA treated with neoadjuvant chemoradiation in anticipation for transplantation betwe
169 s article reviews data supporting the use of chemoradiation in NMIBC and discusses emerging biomarker
171 ied X-rays improves the efficacy of standard chemoradiation in resistant and aggressive head and neck
172 A clinical trial investigating the role for chemoradiation in T1 disease that has recurred is underw
173 ased proportion of patients had preoperative chemoradiation in the last 4 years of the study (59% vs.
174 There is an increasing use of neoadjuvant chemoradiation in this group of patients, especially for
175 e induction of adult stem cells could repair chemoradiation-induced tissue injury and prolong overall
179 reas liver transplantation after neoadjuvant chemoradiation is an option for a subset of patients wit
180 done little to improve survival and combined chemoradiation is associated with significant adverse ef
183 ntergroup study has shown that postoperative chemoradiation is effective in improving both disease-fr
185 nts with a complete response to preoperative chemoradiation is frequently reported as a marker of tre
186 Further optimisation of present standard chemoradiation is needed in patients with locally advanc
188 An immunotherapy approach integrated with chemoradiation is safe and demonstrates an overall survi
191 agement in patients with rectal cancer after chemoradiation is the inability to identify a pCR preope
192 k areas (esophagus/rectum) where neoadjuvant chemoradiation is used, the incidence of anastomotic lea
193 ive chemoradiation or postoperative adjuvant chemoradiation is widely practiced in major centers.
194 0, OR: 2.2) CONCLUSIONS:: After preoperative chemoradiation, long-term outcomes of esophageal carcino
196 The authors hypothesized that preoperative chemoradiation might downstage both T2 and T3 lesions an
197 66), including chemotherapy alone (n = 354), chemoradiation (n = 190, including 99 patients who under
200 al excision was performed after preoperative chemoradiation on patients with a complete clinical resp
201 The impact of adjuvant chemotherapy and chemoradiation on survival has been more clearly defined
202 urrently, there is insufficient evidence for chemoradiation only, or nonoperative management (NOM), t
203 patients required hospital admission during chemoradiation or in the postchemoradiation preoperative
206 operable stage II or III NSCLC, treated with chemoradiation or with radiotherapy alone, were extracte
208 ite improvements in survival with aggressive chemoradiation, outcomes for patients diagnosed as havin
209 I trials confirmed the benefit of concurrent chemoradiation over radiation therapy alone, firmly esta
210 suggested an OS advantage for postoperative chemoradiation over surgery alone, although prospective
211 towards studies of adjuvant chemotherapy and chemoradiation, particularly in defining the best regime
213 e III and IV toxicities during the induction chemoradiation phase included esophagitis (38%) and neut
215 nts with cN- tumors treated with neoadjuvant chemoradiation plus surgery do not derive a significant
216 hese reasons, the use of chemotherapy and/or chemoradiation prior to surgery (neoadjuvant therapy) is
223 se for esophageal carcinoma, recent improved chemoradiation regimens have been reported by the French
224 results seem superior to previously reported chemoradiation regimens in more favorable patients.
225 vorably with AFX-C alone or other concurrent chemoradiation regimens tested by the Radiation Therapy
226 logies, the inclusion of newer agents to the chemoradiation regimens, the use of new hypoxic cell rad
231 dual population of cells escapes surgery and chemoradiation, resulting in a typically fatal tumor rec
236 a taxane followed by radiation or concurrent chemoradiation show that the three-drug induction chemot
237 ychological testing of patients treated with chemoradiation shows significant cognitive deficits that
238 therapy, providing an opportunity to deliver chemoradiation specifically to metastatic disease in col
240 growth factor receptor (EGFR) inhibition in chemoradiation strategies in the nonoperative treatment
241 from 2010 to 2014, who underwent neoadjuvant chemoradiation, surgical resection, and adjuvant therapy
244 stage I-III NSCLC and candidates for radical chemoradiation therapy (60 Gy in 30 fractions over 6 wk)
248 once per week; n = 221) for 3 weeks prior to chemoradiation therapy and for 12 weeks after chemoradia
249 patients following fluorouracil (5-FU)-based chemoradiation therapy and provide evidence for a functi
250 with two cycles of chemotherapy followed by chemoradiation therapy and two additional cycles of chem
251 ent induction chemotherapy, and 52% received chemoradiation therapy as well for a median of 6 months
252 ts with HNSCC who were treated by concurrent chemoradiation therapy between March 2002 and December 2
254 the benefit of cetuximab added to concurrent chemoradiation therapy for patients undergoing nonoperat
255 rior to and following neoadjuvant 5-FU-based chemoradiation therapy in a series of colorectal cancer
256 )F-FLT) before and early after initiation of chemoradiation therapy in patients with squamous cell he
258 mall-cell lung cancer (NSCLC) during radical chemoradiation therapy using serial PET/CT with (18)F-FD
259 racellular amplification of chemotherapy and chemoradiation therapy via gold nanoparticle- and laser
260 with glioblastoma who had completed standard chemoradiation therapy, adding TTFields to maintenance t
261 risk of recurrence (including chemotherapy, chemoradiation therapy, and molecular targeted therapies
262 not in a teaching hospital, lack of adjuvant chemoradiation therapy, as well as histopathologic facto
272 imen of preoperative staging and neoadjuvant chemoradiation treatment followed by orthotopic liver tr
273 The addition of bevacizumab to standard chemoradiation treatment for patients with nasopharyngea
274 incorporation of cisplatin into the primary chemoradiation treatment of patients with carcinoma of t
275 cts (ten [26%] vs four [12%], p=0.12) during chemoradiation treatment; the most frequent events were
276 rboplatin once a week (AUC 2); 2 weeks after chemoradiation, two cycles of consolidation chemotherapy
279 e phase II clinical trials of cediranib with chemoradiation vs. chemoradiation alone in nGBM patients
280 ival for the 79 patients who completed chemo-chemoradiation was 18.7 months, with a median survival o
284 f gemcitabine to adjuvant fluorouracil-based chemoradiation was associated with a survival benefit fo
287 strategy used, while the use of preoperative chemoradiation was the most significant factor associate
295 ed with an intensive regimen of preoperative chemoradiation with cisplatin, fluorouracil, and vinblas
296 ced rectal cancers may tolerate preoperative chemoradiation with IGRT as well as younger patients.
298 al etoposide/cisplatin and concurrent AHTRT, chemoradiation with PIEo produced similar median and 2-y
300 esponse to radiation therapy and concomitant chemoradiation would be an important tool to assist the
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