ライフサイエンスコーパス: chemoreceptor

1 receptors located within the brain (central chemoreceptors).

2 sensitivity are not known for any eukaryotic chemoreceptor.

3 pH-sensitive, as expected for a respiratory chemoreceptor.

4 d acid, indicating that it is a bifunctional chemoreceptor.

5 ons that appears to function as an important chemoreceptor.

6 , we infected mice with strains lacking each chemoreceptor.

7 also blocked signaling by Tar, the aspartate chemoreceptor.

8 al and interdependent feedback regulation by chemoreceptors.

9 es CO2/H(+) responsiveness of other putative chemoreceptors.

10 ated with highly duplicated families such as chemoreceptors.

11 mini that send opposing signals in bacterial chemoreceptors.

12 poxaemia and acidosis in peripheral arterial chemoreceptors.

13 s act with high specificity on their cognate chemoreceptors.

14 hrough highly cooperative, ordered arrays of chemoreceptors.

15 which does not rely on previously identified chemoreceptors.

16 kinase CheA, the coupling protein CheW, and chemoreceptors.

17 tions among the P5 domain of CheA, CheW, and chemoreceptors.

18 0 s), suggesting the activation of extraoral chemoreceptors.

19 each other and with CheA independent of the chemoreceptors.

20 gered by activation of peripheral or central chemoreceptors.

21 ontrolling chemotaxis, utilizes the other 23 chemoreceptors.

22 timulation of the kinase by certain types of chemoreceptors.

23 the mechanism of transmembrane signaling in chemoreceptors.

24 aling in the cytoplasmic domain of bacterial chemoreceptors.

25 ple chemotaxis systems and a large number of chemoreceptors.

26 le effect on the CO2/H(+)-sensitivity of RTN chemoreceptors.

27 ild-type (WT) mice, and smaller responses to chemoreceptor activation when anesthetized.

28 ould not be attributed to changes of central chemoreceptor activity (hypocapnia prevailed); altered a

29 at the cellular level that ACh increases RTN chemoreceptor activity by a CO2/H(+) independent mechani

30 nstantaneous increase or decrease of central chemoreceptor activity by activating or inhibiting the r

31 st the hypothesis that heightened peripheral chemoreceptor activity contributes to both the developme

32 stive heart failure (CHF), carotid body (CB) chemoreceptor activity is enhanced and is associated wit

33 muscarinic receptor activation to changes in chemoreceptor activity may provide new potential therape

34 The effects of ACh on RTN chemoreceptor activity were also blunted by inhibition o

35 nstantaneous increase or decrease of central chemoreceptor activity.

36 w are associated with increased carotid body chemoreceptor activity.

37 osensory system, which exhibits near-perfect chemoreceptor adaptation.

38 of fluorescent tracer onto carotid body for chemoreceptor afferents or onto aortic depressor nerve f

39 ansmembrane (TM) helices of Escherichia coli chemoreceptors alone are sufficient to mediate clusterin

40 l complex perturbs the polar localization of chemoreceptors, alters cell motility, and affects chemot

41 nce to characterize the interaction modes of chemoreceptor and CheW from Thermotoga maritima.

42 ave been determined, the interaction between chemoreceptor and CheW is still unclear.

43 irect observation of the interaction between chemoreceptor and CheW.

44 ial to maintain the correct alignment of the chemoreceptor and kinase binding sites of CheW.

45 owards As(III), however, the related As(III) chemoreceptor and regulatory mechanism remain unknown.

46 , a model organism for chemotaxis that has 5 chemoreceptors and a single chemosensory pathway, Pseudo

47 two species, Salmonella genomes contain some chemoreceptors and an additional protein, CheV, that are

48 ylation of the cytosolic signaling domain of chemoreceptors and are among the core proteins of chemos

49 A CheW had essentially the same affinity for chemoreceptors and CheA, cells expressing the mutant pro

50 Like other bacteria, H. pylori uses chemoreceptors and conserved chemotaxis proteins to phos

51 deamidate selected residues to activate the chemoreceptors and enable them to mediate amino acid che

52 the coupling protein CheW, which bridges the chemoreceptors and histidine kinase CheA, is essential f

53 ives autophosphorylation control inputs from chemoreceptors and in turn regulates the flux of signali

54 periplasmic sensory domains of transmembrane chemoreceptors and induce a conformational change that i

55 m of neuromodulation mediated by the carotid chemoreceptors and involving both the sympathetic and pa

56 a has also evolved an expanded repertoire of chemoreceptors and odorant binding proteins, many associ

57 ASK-2, GPR4), synaptic input from peripheral chemoreceptors and signals from astrocytes.

58 an exquisitely high density of 3 x 10(5) GC chemoreceptors and subnanomolar ligand affinity provide

59 protein that mediates the association of the chemoreceptors and the CheA kinase in a ternary signalin

60 largely redundant abilities to interact with chemoreceptors and the CheA kinase, and both similarly a

61 se CheA, which forms signaling clusters with chemoreceptors and the coupling protein CheW at the pole

62 rtion of RTN neurons are central respiratory chemoreceptors and there is mounting evidence for bioche

63 show that AgTRPA1 is an inherent thermo- and chemoreceptor, and analogous to what has been reported f

64 sponse gains physiological, and carotid body chemoreceptors are driven by a wide range of O2 and/or C

65 Central chemoreceptors are highly sensitive neurons that respond

66 gests that the principal central respiratory chemoreceptors are located within the retrotrapezoid nuc

67 Bacterial chemoreceptors are long helical proteins that consist of

68 SRB chemoreceptors are not essential for sperm navigation un

69 The principal peripheral chemoreceptors are the carotid bodies (CBs) and alterati

70 Most bacterial chemoreceptors are transmembrane proteins.

71 Bacterial chemoreceptors are widely used as a model system for elu

72 graphy, we explore V. cholerae's cytoplasmic chemoreceptor array and establish that it is formed by p

73 ns may be used to provide flexibility in the chemoreceptor array formation.

74 to their environment through a transmembrane chemoreceptor array whose structure and function have be

75 Across bacterial species, chemoreceptor arrays (both transmembrane and soluble) ar

76 The best-studied bacterial chemoreceptor arrays are membrane-bound.

77 Chemoreceptor arrays are supramolecular transmembrane ma

78 and CheW(3) are involved in the assembly of chemoreceptor arrays at the cell poles.

79 These findings confirm that chemoreceptor arrays do not undergo large structural cha

80 During bacterial chemotaxis, transmembrane chemoreceptor arrays regulate autophosphorylation of the

81 redundant for formation of the higher order chemoreceptor arrays that are known to form via CheA-Che

82 Together with direct visualization of chemoreceptor arrays, DNA packing, periplasmic filaments

83 s of nearly all the individual components of chemoreceptor arrays, ECT has revealed the mesoscale inf

84 st common applications has been to bacterial chemoreceptor arrays, ECT's contributions to this field

85 elf-assembly both of flagellar motors and of chemoreceptor arrays.

86 spensable for chemotaxis and assembly of the chemoreceptor arrays.

87 ligomerization patterns observed for related chemoreceptors, as higher loading of Aer dimers into nan

88 ine activity and CO2/H(+)-sensitivity of RTN chemoreceptors, as well as to dissect the signalling pat

89 em consists of large arrays of transmembrane chemoreceptors associated with a dedicated histidine kin

90 typical example is the assembly of bacterial chemoreceptors at cell poles.

91 e molecule level the polarization of GABA(A) chemoreceptors at the GC membrane, as a function of the

92 In rat arterial chemoreceptors, background potassium channels play an im

93 c responses to apnoea result from changes of chemoreceptor, baroreceptor or lung stretch receptor inp

94 ur study, could not be attributed to altered chemoreceptor, baroreceptor, or pulmonary stretch recept

95 Chemoreceptor-based signaling is a central mechanism in

96 o suggest that >75% of these Nmb neurons are chemoreceptors because they are strongly activated by hy

97 Thus, chemoreceptors behave as coupled units, in which dynamic

98 We find that chemoreceptor binding surface is located near the highly

99 Moreover, CheD, which activates chemoreceptors, binds better to McpC-Q609E compared with

100 acterial cell (e.g. type IV pili, holdfasts, chemoreceptors), but perhaps none show so many distinct

101 These results show that ACh activates RTN chemoreceptors by a CO2/H(+) independent mechanism invol

102 Stimulation of peripheral chemoreceptors by acute hypoxia causes an increase in mi

103 Activation of central chemoreceptors by CO2 increases arterial blood pressure

104 Activation of central chemoreceptors by CO2 increases sympathetic nerve activi

105 tments elicited, at least partly, by central chemoreceptors (CCRs) and the carotid bodies (CBs).

106 nergic Phox2b-expressing central respiratory chemoreceptors (CCRs), is the site of such plasticity.

107 to peripheral control of breathing, central chemoreceptors (CCs) are considered a dominant mechanism

108 both adenosine and dopamine release from CB chemoreceptor cells was increased in chronic hypoxia and

109 (TRPA1), and that HNO activates the sensory chemoreceptor channel TRPA1 via formation of amino-termi

110 directly to the sensory complexes formed by chemoreceptors, CheA and an adapter protein CheW.

111 tron cryotomography to image the cytoplasmic chemoreceptor cluster in Rhodobacter sphaeroides and Vib

112 in curved agar microchambers, and find that chemoreceptor cluster localization is highly sensitive t

113 of the protein complex and does not rely on chemoreceptor clustering, as was previously shown for Es

114 the system's components, it is not clear how chemoreceptor clusters are reliably targeted to the cell

115 li Tol-Pal complex restricts mobility of the chemoreceptor clusters at the cell poles and may be invo

116 utes to the segregation and retention of Tsr chemoreceptor clusters at the cell poles.

117 equired to maintain the polar positioning of chemoreceptor clusters in Escherichia coli.

118 interaction is required to polarly localize chemoreceptor clusters.

119 The carotid body (CB) is a major arterial chemoreceptor containing glomus cells whose activities a

120 ring REM sleep because fR is no longer under chemoreceptor control and thus could explain why central

121 ting opposite effects on central respiratory chemoreceptors (CRCs).

122 Further assessments of single chemoreceptor deletion strains revealed that an mcpX del

123 nflammatory network was abrogated by carotid chemoreceptor denervation and by pharmacological blockad

124 ugh much is known about the structure of the chemoreceptors, details of the receptor dynamics and the

125 mplexes contain two trimers of transmembrane chemoreceptor dimers, each trimer binding a coupling pro

126 ing of chemo-effectors to the membrane-bound chemoreceptor dimers.

127 We used this model to explore chemoreceptor discharge patterns in response to electric

128 presence of CheR, a variety of mutant serine chemoreceptors displayed up to 40-fold enhanced detectio

129 tein harboring two sensory PAS domains and a chemoreceptor domain, TarH.

130 in an autocrine manner to enhance peripheral chemoreceptor drive.

131 Transient inhibition of the carotid chemoreceptors during moderate intensity exercise reduce

132 The N-terminal domain of a cytoplasmic chemoreceptor encoded next to ppfA is also required for

133 factory receptor neurons (ORNs) that express chemoreceptors encoded by large gene families, including

134 Genomic analyses revealed a putative chemoreceptor-encoding gene, mcp, located in the arsenic

135 membranes and in this way mimic the natural chemoreceptor environment.

136 ts--somatic sex, age, and feeding status--on chemoreceptor expression highlights sensory function as

137 For several chemoreceptor families, we show divergent numbers of gen

138 oducing planarians, and identified an orphan chemoreceptor family member, ophis, that controls differ

139 that the two sensory inputs alter different chemoreceptor features.

140 discuss the potential relevance of this dual chemoreceptor feedback to cardiorespiratory abnormalitie

141 x chemosensory network, which consists of 26 chemoreceptors feeding into four chemosensory pathways.

142 the kinase-activating cytoplasmic tip of the chemoreceptor fluctuates between two stable conformation

143 When this region was replaced with that of a chemoreceptor for amino acids, WspA became polarly local

144 opose to rename Tlp11 as CcrG, Campylobacter ChemoReceptor for Galactose.

145 Chemoreceptors form large clusters in many bacterial spe

146 fragments of normally transmembrane E. coli chemoreceptors form similar sandwiched structures in the

147 interacts with specific domains of CheA and chemoreceptors from an orthologous group exemplified by

148 ructure, but have some affinity bias towards chemoreceptors from different orthologous groups.

149 crystal structure of cytoplasmic domains of chemoreceptors from Escherichia coli.

150 nding molecular mechanisms that regulate RTN chemoreceptor function may identify therapeutic targets

151 le of KCNQ channels in the regulation of RTN chemoreceptor function, and suggest that these channels

152 rophic shifts in insects are associated with chemoreceptor gene loss as recently evolved ecologies sh

153 udes alternative alleles of srx-44, a second chemoreceptor gene that modifies pheromone sensitivity.

154 Here we show that peripheral chemoreceptors generate aberrant signaling that contribu

155 esults and genome-wide evidence suggest that chemoreceptor genes may be preferred sites of adaptive v

156 current model of O2 sensing by carotid body chemoreceptor (glomus) cells is that hypoxia inhibits th

157 chemotaxis have long been speculated, such a chemoreceptor has not been demonstrated.

158 ee-dimensional structures of CheA, CheW, and chemoreceptors have been determined, the interaction bet

159 Various classes of chemoreceptors have been hypothesized to play essential

160 Peripheral arterial chemoreceptors have been isolated to the common carotid

161 Peripheral arterial chemoreceptors have been located previously in the carot

162 is recently appreciated that many bacterial chemoreceptors have ligand-binding domains (LBD) of the

163 tive neurotransmitters associated with these chemoreceptors have not yet been described.

164 ion of both peripheral (hypoxia) and central chemoreceptors (hypercapnia).

165 selective ablation of the carotid body (CB) chemoreceptors improves cardiorespiratory control and su

166 When mcpC-Q609E is expressed as the sole chemoreceptor in a cheD background, chemotaxis is almost

167 When McpC was the sole chemoreceptor in a cheD mutant, chemotaxis to proline wa

168 We find that CheA interacts with a chemoreceptor in a manner similar to that of CheW, and t

169 In a cheD mutant when McpB was the sole chemoreceptor in B. subtilis, chemotaxis to asparagine w

170 The GC chemoreceptor in sea urchin sperm can decode chemoattrac

171 We found that ACh activates RTN chemoreceptors in a dose-dependent manner (EC50 = 1.2 mu

172 report the identification of a novel type of chemoreceptors in human keratinocytes, the olfactory rec

173 tify the curvature-dependent localization of chemoreceptors in live cells by artificially deforming g

174 interaction among the peripheral and central chemoreceptors in rats.

175 pecies also contain an additional cluster of chemoreceptors in their cytoplasm.

176 lial cells (NECs), which are putative oxygen chemoreceptors, increased significantly when these cells

177 Instead, our data indicate that chemoreceptors interact with components of the Tol-Pal c

178 e that hyperaddition is the dominant form of chemoreceptor interaction in quiet wakefulness when the

179 Our model of bilayer-chemoreceptor interactions also helps to explain the obs

180 we introduce a biophysical model of bilayer-chemoreceptor interactions, which allows us to quantify

181 subtilis and gain insight into how a single chemoreceptor is able to sense many amino acids.

182 Although less than 10% of a transmembrane chemoreceptor is embedded in lipid, separation from the

183 To determine which chemoreceptor is responsible for the corpus-antrum pheno

184 Thus the chemoreceptor is strongly influenced by its lipid enviro

185 The reason for the difference between the chemoreceptors is because CheD deamidates Q609 in McpC a

186 species, the presence of a larger number of chemoreceptors is likely to contribute to the ability of

187 nsion monitored by the peripheral (arterial) chemoreceptors is not sensitive to regional CNS differen

188 The mechanism of oxygen sensing in arterial chemoreceptors is unknown but has often been linked to m

189 s, suggests a series of "gateway" states for chemoreceptor lattice assembly, and provides a simple me

190 dicts the observed honeycomb architecture of chemoreceptor lattices as well as the observed relative

191 -mediated interactions can yield assembly of chemoreceptor lattices at very dilute trimer concentrati

192 The signaling response of the observed chemoreceptor lattices is remarkable for its extreme sen

193 mple mechanism for the localization of large chemoreceptor lattices to the cell poles.

194 ractions in the assembly and architecture of chemoreceptor lattices.

195 n HFpEF and that acute activation of central chemoreceptors leads to increases of cardiac sympathetic

196 oattractants sensed by only one of the major chemoreceptors leads to inversion of the thermotactic re

197 trolling a histidine kinase as a function of chemoreceptor ligand occupancy.

198 In this report, we demonstrated that the chemoreceptor MCP2901 from Comamonas testosteroni CNB-1

199 Loss of a single chemoreceptor, McpC, was previously found to reduce chem

200 was proposed to result from stochasticity in chemoreceptor methylation, and it is believed to enhance

201 s into the molecular signaling mechanisms of chemoreceptor networks.

202 re the olfactory circuit by regulating a key chemoreceptor, odr-10, in the AWA neurons.

203 The serine chemoreceptor of Escherichia coli contains four canonica

204 on of this Gly residue in the high-abundance chemoreceptors of E. coli and Salmonella enterica sugges

205 The chemoreceptors of Escherichia coli localize to the cell

206 o derive homologies with peripheral arterial chemoreceptors of other vertebrates.

207 ve (CSN) conveys electrical signals from the chemoreceptors of the carotid bifurcation to the central

208 d cryo-electron tomography revealed that the chemoreceptors of the Lyme disease spirochete Borrelia b

209 Some chemoreceptors of the trace amine-associated receptor (T

210 t is not known whether LITE-1 functions as a chemoreceptor or photoreceptor.

211 domain (from Tsr or from several Pseudomonas chemoreceptors), or lacking nearly the entire periplasmi

212 Bacterial chemoreceptors organize into large clusters at the cell

213 g activity even in the absence of peripheral chemoreceptor oxygen sensing.

214 ensory pathways in P. aeruginosa utilize one chemoreceptor per pathway, whereas the fourth pathway, w

215 Carotid chemoreceptors play a seminal role in the pathogenesis o

216 e find that modulated expression of a single chemoreceptor plays a key role in naturally occurring va

217 ss low-to-moderate levels of Nmb and display chemoreceptor properties.

218 is amplified across a 53,000 nm(2) array of chemoreceptor proteins, including approximately 5,200 re

219 cals in their environment with transmembrane chemoreceptor proteins.

220 Bacterial chemoreceptors provide an important model for understand

221 ive sequence analysis specifically targeting chemoreceptor regions involved in pathway interactions r

222 s.SIGNIFICANCE STATEMENT Central respiratory chemoreceptors regulate arterial PCO2 by adjusting lung

223 understand the molecular mechanisms by which chemoreceptors regulate social behaviors, we investigate

224 by which CO(2)/H(+) -sensitive neurons (i.e. chemoreceptors) regulate breathing in response to change

225 nd in vitro, and whether purinergic drive to chemoreceptors relies on extracellular Ca(2+) or gap jun

226 electron cryo-tomography have revealed that chemoreceptors self-assemble into extended honeycomb lat

227 Central respiratory chemoreceptors sense changes in CO2/H(+) and initiate th

228 A sensory adaptation system that tunes chemoreceptor sensitivity enables motile Escherichia col

229 Because the sequences of chemoreceptor signaling domains are highly conserved, it

230 otation and piston-like motion for bacterial chemoreceptor signaling.

231 electron cryotomography to visualize mutant chemoreceptor signalling arrays in well-defined kinase a

232 ctivation is the default output state of the chemoreceptor signalling domain and that attractant stim

233 nergistically to regulate firing rate of RTN chemoreceptors; simultaneous blockade of both channels l

234 lostery in core complexes assembled with two chemoreceptor species, each recognizing a different liga

235 nd hypoxia and hypercapnia episodes activate chemoreceptors stimulating autonomic reflex responses.

236 ve discharge was attenuated and responses to chemoreceptor stimulation and noxious stimulation were b

237 reflexes are arousal state dependent whereas chemoreceptor stimulation produces arousal.

238 d sympathoexcitatory responses to peripheral chemoreceptor stimulation.

239 rsomedial hypothalamus are activated by both chemoreceptor stimuli.

240 We asked if the type of carotid body (CB) chemoreceptor stimulus influenced the ventilatory gain o

241 and CheW share the same binding spot on the chemoreceptor structure, but have some affinity bias tow

242 re additional, sometimes purely cytoplasmic, chemoreceptor systems.

243 amics of the periplasmic domain of aspartate chemoreceptor Tar dimer and its conformational changes w

244 ted effects of membrane lipid composition on chemoreceptor Tar from Escherichia coli using Nanodiscs,

245 ackbones in the cytoplasmic domain of intact chemoreceptor Tar homodimers inserted into lipid bilayer

246 ic domains of the Escherichia coli aspartate chemoreceptor Tar(Ec) are both strongly influenced by re

247 ith opposite pH responses from two different chemoreceptors (Tar and Tsr).

248 hia coli, the ratio of the two most abundant chemoreceptors, Tar/Tsr, has become the focus of much at

249 (NTS), where afferent endings from arterial chemoreceptors terminate.

250 at includes alternative alleles of srx-43, a chemoreceptor that inhibits exploration through its acti

251 ch utilizes specialized sensory organs and a chemoreceptor that is tuned to recognize the bacteria.

252 This is the first report of a chemoreceptor that mediates QACs taxis through direct bi

253 Although the existence of chemoreceptors that bind to aromatic attractants and sub

254 linking the CheA kinase to certain types of chemoreceptors that cannot be effectively accommodated b

255 The carotid bodies (CB) are peripheral chemoreceptors that classically respond to hypoxia by in

256 Drosophila contains diverse families of chemoreceptors that detect odors, tastants, pheromones,

257 Olfactory sensory neurons (OSNs) are chemoreceptors that establish excitatory synapses within

258 inus and N-terminal periplasmic domains from chemoreceptors that sense amino acids or malate responde

259 of the carotid body (peripheral respiratory chemoreceptors) that stimulate breathing when oxygenatio

260 In bacterial chemotaxis, transmembrane chemoreceptors, the CheA histidine kinase, and the CheW

261 nvestigated the roles of a critical class of chemoreceptors, the odorant receptors (ORs), from the po

262 In the Tsr chemoreceptor, they convert a signal initiated by bindin

263 Here we show that the classical chemoreceptor TlpA of Bacillus subtilis does not localiz

264 ponse is largely controlled by the bacterial chemoreceptor TlpB, and the main attractant emanating fr

265 ure of dCACHE LBD of the Helicobacter pylori chemoreceptor TlpC.

266 The firing response of RTN chemoreceptors to ACh was mimicked by a muscarinic recep

267 roles in B. subtilis chemotaxis - to bind to chemoreceptors to activate them as part of the CheC/CheD

268 fluenced the ventilatory gain of the central chemoreceptors to CO2 .

269 that enabled us to unambiguously link all 26 chemoreceptors to four pathways.

270 uced incomplete and uncertain assignments of chemoreceptors to pathways.

271 tor mosquito, Anopheles gambiae, depend upon chemoreceptors to respond to volatiles emitted from a ra

272 native receptor, but simply surrounding the chemoreceptor transmembrane segment with a lipid bilayer

273 ed membranes arises from the curved shape of chemoreceptor trimer of dimers.

274 In common with other membrane proteins, chemoreceptor trimers are expected to deform the surroun

275 assemble into extended honeycomb lattices of chemoreceptor trimers with a well-defined relative orien

276 well as the observed relative orientation of chemoreceptor trimers, suggests a series of "gateway" st

277 e that curvature sensitivity is intrinsic to chemoreceptor trimers-of-dimers, and results from confor

278 ontribute to cooperativity among neighboring chemoreceptor trimers.

279 crucially on cooperative interactions among chemoreceptor trimers.

280 emonstrate that DHMA is sensed by the serine chemoreceptor Tsr and that the chemotaxis response requi

281 e of the homodimeric Escherichia coli serine chemoreceptor (Tsr) interacts with an adjoining four-hel

282 E402 and R404 of the Escherichia coli serine chemoreceptor, Tsr, appear to form a salt bridge that sp

283 d the mobility of the polar localized serine chemoreceptor, Tsr, labeled by the fluorescent protein V

284 Localization of the chemoreceptors was independent of phospholipid compositi

285 n the ventilatory CO2 sensitivity of central chemoreceptors was studied in seven awake dogs with vasc

286 Chemoreceptors were inserted in Nanodiscs, which rendere

287 While several chemoreceptors were rigorously linked to specific pathwa

288 O2 titrated) and central (7% CO2 and 93% O2) chemoreceptors were stimulated for 3 minutes.

289 This contrasts with most chemoreceptors where signals propagate along the protein

290 , the vast majority, are central respiratory chemoreceptors, whereas Nmb-high neurons likely have oth

291 The genes encoding the Tar, Tsr, and Aer chemoreceptors, which mediate chemotaxis to a broad spec

292 y underwent an ancestral loss of Trg and Tap chemoreceptors, which sense sugars, dipeptides, and pyri

293 ys that control this directionality comprise chemoreceptors, which, along with an adaptor protein (Ch

294 We further identify a chemoreceptor with an unusual domain architecture, DosM,

295 In humans, excitation of peripheral chemoreceptors with systemic hypoxia causes hyperventila

296 dditional adaptor for accommodating specific chemoreceptors within the chemotaxis signaling complex.

297 her modulators, controls the activity of RTN chemoreceptors without interfering with the mechanisms b

298 ypothesized that denervation of the CB (CBD) chemoreceptors would reduce SNA, reduce apnoea and arrhy

299 However, unlike standard chemoreceptors, WspA does not form stable clusters at ce

300 atiation while minimally affecting brainstem chemoreceptor zones triggering nausea.