ライフサイエンスコーパス: childhood

1 bidity after traumatic brain injury in early childhood.

2 f the projected prevalence will occur during childhood.

3 G mutation, or both and IgE sensitization in childhood.

4 he diagnostic relevance of such molecules in childhood.

5 d 205 participants followed clinically since childhood.

6 tis media (OM) is the most common illness in childhood.

7 with greater anxiety/depression during late childhood.

8 quent cause of severe physical disability in childhood.

9 al delay without dystonia at least until mid-childhood.

10 not able to acquire immune tolerance during childhood.

11 ilepsy, ultimately leading to death in early childhood.

12 elopmental impairment and four died in early childhood.

13 life-threatening disease phenotype in early childhood.

14 the same condition, with one having died in childhood.

15 llowed by further patchy pigment loss during childhood.

16 The symptoms of C1-INH-HAE often present in childhood.

17 processing of depth information even in late childhood.

18 0; 95% CI, 0.86-1.16) and type 1 diabetes in childhood.

19 ized by neurodegeneration and death in early childhood.

20 s beyond the perinatal period and into early childhood.

21 s of patients followed longitudinally beyond childhood.

22 s one of the most common chronic diseases of childhood.

23 ated with lower cognitive performance during childhood.

24 Recurrent wheeze (RW) is frequent in childhood.

25 g, and in buccal epithelium and blood during childhood.

26 parated 4 phenotypes of atopic dermatitis in childhood: 2 early phenotypes with onset before age 2 ye

27 learance occurred predominantly in the early childhood, 20-24 and 35-39 year age groups.

28 003, 2004, and 2005) and again during middle childhood (2009-2011) for a follow-up assessment that in

29 Childhood absence epilepsy (CAE) is the most common paed

30 functional neurological symptom severity or childhood abuse.

31 ETV6-RUNX1 is associated with childhood acute B-lymphoblastic leukemia (cALL) function

32 Purpose Survivors of childhood acute lymphoblastic leukemia (ALL) are at risk

33 een socioeconomic position (SEP) and risk of childhood acute lymphoblastic leukemia (ALL) were invest

34 d with resistance to asparaginase therapy in childhood acute lymphoblastic leukemia.

35 Previous studies in childhood acute myeloid leukemia (AML) have shown a nega

36 Childhood acute myeloid leukemia (AML) is frequently cha

37 ions on how to use bronchodilators to manage childhood acute wheezing conditions in the emergency dep

38 analysis, we found support for an effect of childhood adiposity on T1D risk (odds ratio 1.32, 95% CI

39 ught to investigate the associations between childhood/adolescence cardiovascular risk factors and mi

40 ven that these disorders frequently begin in childhood/adolescence, an understanding of fear-extincti

41 n patients was significantly associated with childhood adversity (T = 2.3; P = .03).

42 he scientific literature on the influence of childhood adversity on cardiometabolic outcomes that con

43 a (BPD) and respiratory disease during early childhood after preterm birth, we performed a prospectiv

44 We treated 10 childhood ALL patient-derived xenograft models harboring

45 section was associated with a higher risk of childhood ALL, especially at the peak ages of incidence.

46 arean section (C-section) in the etiology of childhood ALL.

47 atopic march is the primary causal factor in childhood allergic disease.

48 ry effects that influence the development of childhood allergic sensitization and atopic diseases.

49 ole after transplant as it once did in early childhood, allowing a more complete restoration of the T

50 RETATION: Globally, RSV is a common cause of childhood ALRI and a major cause of hospital admissions

51 , AMKL accounts for 4-15% of newly diagnosed childhood AML cases.

52 We suggest that the extended human childhood and adolescence allows a balance between explo

53 increased risk of developing obesity during childhood and adolescence compared with children without

54 stricted and anisotropic in the brain during childhood and adolescence, as fibre bundles develop and

55 Adverse experiences in childhood and adolescence, defined as subjectively perce

56 otracted maturation of this circuitry across childhood and adolescence.

57 al modules that have been shown to evolve in childhood and adolescence.

58 gitudinal birth cohort studies is similar in childhood and adolescence/early adulthood.

59 en diagnosis/referent date and birth between childhood and adolescent cancer survivors and an age-mat

60 e two miRNAs were also found dysregulated in childhood and adult PA patients' cohorts.

61 that tackle inequality with respect to both childhood and adult SEP are urgently required.

62 th is associated with increased adiposity in childhood and adulthood have been based on analyses "adj

63 may be associated with rapid growth in early childhood and body composition in young adulthood.

64 fect nearly every person in the world during childhood and cause diarrhea, vomiting, and fever.

65 were associated with academic performance in childhood and early adolescence.

66 Asthma is a common disease in childhood and is often preceded by wheezing illnesses du

67 ribes the most common physical disability in childhood and occurs in 1 in 500 live births.

68 vioral dysfunctions, developmental delays in childhood and risk of developing schizophrenia and autis

69 hildren's weight and body composition across childhood and to explore a possible mediating role of ma

70 birth before 32 weeks of gestation and HF in childhood and young adulthood.

71 and emotional problems often start in early childhood, and this might be particularly important in A

72 ture and function from infancy through early childhood, and this significantly influences cognitive a

73 different temperatures in utero and in early childhood, and we estimate flexible regression models th

74 persistence or resolution of food allergy in childhood are not understood.

75 associations with wheeze and asthma in later childhood are scarce and did not account for inherent co

76 its effects on respiratory function in later childhood are unknown.

77 The Deferred Action for Childhood Arrivals (DACA) program granted temporary prot

78 early-life farming exposures protect against childhood asthma and allergy; few data exist on asthma a

79 Childhood asthma develops from a complex interaction amo

80 cillus Calmette-Guerin (BCG) vaccination and childhood asthma in a birth cohort using administrative

81 that involvement of epigenetic mechanisms in childhood asthma is already demonstrable at birth.

82 Persistent childhood asthma is mainly atopy driven.

83 verweight in the association between LGA and childhood asthma is unclear.

84 was attempted in 2 independent cohorts, the Childhood Asthma Management Program (CAMP) and the Genet

85 e calculated for children with asthma in the Childhood Asthma Management Program.

86 haemoglobin was not associated with risk of childhood asthma or other allergic disorders.

87 , limited data exist on the risk factors for childhood asthma phenotypes.

88 d dogs has shown diverging associations with childhood asthma risk, and gene-environment interaction

89 l hypothyroidism in the perinatal period and childhood asthma risk.

90 of asthmatic mothers and was associated with childhood asthma risk.

91 tify gene-environment interaction effects on childhood asthma using genome-wide single-nucleotide pol

92 URECA (Urban Environment and Childhood Asthma) is a birth cohort at high risk for ast

93 rgic sensitizations are common in persistent childhood asthma, and thorough assessment of allergy is

94 pecially to cat, for attenuating the risk of childhood asthma, pneumonia, and bronchiolitis in geneti

95 ted with the development and exacerbation of childhood asthma.

96 en may be an area for possible prevention of childhood asthma.

97 ed from a nationwide Swedish study on severe childhood asthma.

98 eural processes tied to the adult outcome of childhood attention deficit hyperactivity disorder (ADHD

99 for early detection and treatment to prevent childhood blindness in world health organization program

100 Mutations in this gene cause childhood blindness, in which the a- and b-wave response

101 Associations of childhood blood lead level with deficits in verbal compr

102 cy BMI peak characteristics and higher early childhood BMI.

103 ailable for investigating genomic aspects of childhood brain tumors in both the research and the clin

104 cular landscapes of human cancers, including childhood brain tumors.

105 mponents of cardiometabolic (CM) risk during childhood, but evidence is scarce and inconsistent.

106 l increases in adiposity measurements in mid-childhood, but only among girls.

107 ol prevails after TEPT in HD patients during childhood, but symptoms diminish with age.

108 Among 23603 survivors of childhood cancer (mean age at diagnosis, 7.7 years; 46%

109 Results Among 580 survivors of childhood cancer and 173 siblings, survivors of childhoo

110 re or changing lifestyle) among survivors of childhood cancer and a sibling comparison group.

111 ted data on CHCs in all patients treated for childhood cancer at the St Jude Children's Research Hosp

112 Survivors of childhood cancer develop early and severe chronic health

113 Conclusion Risk factors for early death in childhood cancer include an age younger than 1 year, spe

114 RETATION: The burden of CHCs in survivors of childhood cancer is substantial and highly variable.

115 Purpose Survivors of childhood cancer may experience financial burden as a re

116 Patients and Methods Participants in the Childhood Cancer Survivor Study (CCSS; n = 13,060) were

117 eported adverse health status outcomes among childhood cancer survivors across 3 decades.

118 sks of cardiac morbidity and mortality among childhood cancer survivors have been described previousl

119 Childhood cancer survivors with hypertension after anthr

120 to risk for the more common late effects of childhood cancer therapy.

121 Purpose Survivors of childhood cancer treated with cranial radiation therapy

122 ldhood cancer and 173 siblings, survivors of childhood cancer were more likely to have out-of-pocket

123 tumors and replicated these in survivors of childhood cancer with and without subsequent CNS tumors

124 ed with subsequent neoplasms in survivors of childhood cancer.

125 rt disease and stroke in 5-year survivors of childhood cancer.

126 suffer from a higher degree of severe early childhood caries (S-ECC) than the general population, le

127 e-biofilms from children affected with early-childhood caries, a prevalent and costly oral disease.

128 ften detected with Candida albicans in early childhood caries.

129 a (JMML) is a myeloproliferative disorder of childhood caused by mutations in the Ras pathway.

130 lycerides, type 2 diabetes, waist-hip ratio, childhood cognitive ability, neuroticism, bipolar disord

131 INTERPRETATION: Childhood cognitive, social, behavioural, and emotional

132 cal serotypes and respiratory viruses during childhood community-acquired alveolar pneumonia (CAAP).

133 SES measurements for childhood (composite score including parents' educationa

134 ted with higher child adiposity, but earlier childhood concentrations were not.

135 ed these hypotheses in adults followed since childhood, contrasting remitted against persistent ADHD.

136 Rapid-growth patterns in early childhood could be a mediating link between infant feedi

137 ive study, we followed up a population-based childhood CSE cohort from north London, UK (the north Lo

138 INTERPRETATION: Childhood CSE is associated with substantial long-term n

139 stand the connections between land cover and childhood DD, we compiled a database of 293,362 children

140 ain the leading cause of vaccine-preventable childhood death, even though highly effective pneumococc

141 Globally, the majority of childhood deaths in the post-neonatal period are caused

142 erstood as to how stress experienced in late childhood, defined as preadolescence, alters the program

143 Despite progress, early childhood development (ECD) remains a neglected issue, p

144 Services and interventions to support early childhood development are essential to realising the vis

145 aise healthcare professionals' management of childhood diarrhea in low-income countries.

146 ium is a leading cause of moderate to severe childhood diarrhea in resource-poor settings.

147 ted with college completion vary by level of childhood disadvantage for depression and metabolic synd

148 lic syndrome for whites across all levels of childhood disadvantage.

149 Hunter syndrome is a rare but devastating childhood disease caused by mutations in the IDS gene en

150 Although often described as a childhood disease, newer population-based estimates sugg

151 e agent of dental caries, the most prevalent childhood disease.

152 n explaining some of the variation in global childhood eczema prevalence.

153 rt Network (FluCAN) study and the Australian Childhood Encephalitis (ACE) study between 2013 and 2015

154 Within the Pregnancy and Childhood Epigenetics (PACE) Consortium, we meta-analyse

155 Childhood epilepsies are frequently severe, presenting i

156 The rates of childhood epilepsy increased with maternal overweight or

157 Risk of childhood epilepsy.

158 c health strategy to reduce the incidence of childhood epilepsy.

159 Adverse childhood experiences (ACEs) are one of the greatest pre

160 Adverse childhood experiences (ACEs) have been associated with p

161 pstream causes of exclusion, such as adverse childhood experiences and poverty.

162 Childhood exposure to a farm environment has been shown

163 vestigated longitudinal associations between childhood exposure to phenols, from both manmade and nat

164 all difference in academic performance after childhood exposure to surgery is reassuring.

165 n adulthood may be rooted partially in early childhood exposure to unpredictable events and environme

166 tal maternal stress may increase the risk of childhood externalizing disorders, yet no large cohort s

167 related early-life exposures including early childhood farm animal contact and raw milk consumption.

168 r General's Social Class) was ascertained in childhood (father's class at 10/11 y) and adulthood (42/

169 ween antenatal maternal vitamin D status and childhood fractures.

170 Congenital and childhood glaucomas have strong genetic bases and diseas

171 o required in three later phases: the middle childhood growth and consolidation phase (5-9 years), wh

172 stational weight gain (GWG), birth size, and childhood growth factors with adult BMI in daughters at

173 manifestations, particularly asthma, during childhood had a lower proportion of IgA bound to fecal b

174 ure to parental separation or divorce during childhood has been associated with an increased risk for

175 In clinical settings, wasting in childhood has primarily been assessed with the use of a

176 se action on community-level determinants of childhood HAZ trajectories.

177 tivariate analysis (King's Outcome Scale for Childhood Head Injury score < 5a) in the development coh

178 reas adult HGG has been studied extensively, childhood HGG, a relatively rare disease, is less well-c

179 The lesion was present since childhood; however, it increased in in size over the pre

180 d classic Bartter syndrome (diagnosis during childhood, hypercalciuria, and/or polyuria), and 26.0% h

181 red scarring or both - are a common cause of childhood hypertension and renal failure.

182 uct disorder and 2) hyperactivity throughout childhood, identified using latent class growth modeling

183 tools, such as the Integrated Management of Childhood Illness (IMCI) algorithm, rely solely on clini

184 ary outcome was WHO Integrated Management of Childhood Illness (IMCI)-defined pneumonia episodes in c

185 a prospective multicenter cohort: the French Childhood Immune Deficiency Long-term Cohort.

186 oviding new insights into the shaping of the childhood immune system.

187 ete, recent infection, non-recent infection, childhood infection - depending on the disease in questi

188 The management of childhood infections remains inadequate in resource-limi

189 cterized by intense pruritis and is a common childhood inflammatory disease.

190 25(OH)D deficiency in early childhood is associated with increased risk for persiste

191 Exposure to dangerous environments in childhood is associated with poor context encoding in th

192 g of onset and progression of the disease in childhood is lacking.

193 For atopy, definition of phenotypes during childhood is less clear.

194 ion between growth and bone accretion during childhood is not fully understood.

195 t the time of stroke but suggests testing in childhood is not indicated.

196 Significant elevations in the risk of childhood leukemia have been associated with environment

197 etreatment tumor samples from the California Childhood Leukemia Study.

198 sm evolves significantly with age throughout childhood, limiting their clinical applicability.

199 ction of adult dyslipidemia in comparison to childhood lipid measures.

200 (levels <100 U/L), were identified across 14 Childhood Liver Disease Research Network (ChiLDReN) cent

201 To investigate the role of childhood lung function in adult COPD phenotypes.

202 at childbirth has repeatedly been linked to childhood malignancies, while few studies have focused o

203 We did a comprehensive meta-analysis of childhood maltreatment (overall, sexual abuse, physical

204 Finally, childhood maltreatment levels predicted amygdala, but no

205 Our aim was to identify the early childhood manifestations of this liability in a UK popul

206 est that exposure to specific phenols during childhood may influence adiposity through adolescence.

207 Ocular contusion in childhood may not be reported by children.

208 central adiposity in 1,006 children in early childhood (median, 3.2 years) and 876 in mid-childhood (

209 childhood (median, 3.2 years) and 876 in mid-childhood (median, 7.7 years) using anthropometric and d

210 fe exposure to perfluoroalkyl substances and childhood metabolic function.

211 or individuals who experienced trauma during childhood might usefully inform clinicians and public he

212 Neonatal infections are a leading cause of childhood mortality in low-resource settings.

213 ies such as for treatment of inherited early childhood neurodegenerative diseases.

214 seen between infection episodes and risk of childhood obesity (ptrend <0.0001).

215 of measures to reduce the global epidemic of childhood obesity and encourage mechanistic studies.

216 ted in improved family-centered outcomes for childhood obesity and improvements in child BMI.

217 he question as to whether the monocytosis in childhood obesity contributes to atherogenesis over the

218 One hypothesis is that increasing childhood obesity rates may explain part of this increas

219 cted the monocyte gene expression profile in childhood obesity using an Illumina microarray platform

220 5 differentially regulated monocyte genes in childhood obesity with obesity and complexity of coronar

221 Given the current level of childhood obesity, the models predicted that a majority

222 etween antibiotic use in infancy and risk of childhood obesity, with implications for health-care del

223 ention delivery and training initiatives for childhood obesity.

224 influence risk for chronic disease including childhood obesity.

225 The effects of these risk factors from childhood on midlife cognitive performance are unknown.

226 und that (i) encephalopathies with infantile/childhood onset epilepsies (>/=3 months of age) occur al

227 alopathies are a devastating group of severe childhood onset epilepsies with medication-resistant sei

228 ssion is less common than in other causes of childhood onset epilepsy.

229 lated individuals with a complex progressive childhood-onset dystonia, often associated with a typica

230 croarray analysis in adults with unexplained childhood-onset epilepsy and intellectual disability.

231 population-based cohort of individuals with childhood-onset epilepsy in southwestern Finland, togeth

232 Adults with childhood-onset epilepsy, particularly APOE epsilon4 car

233 The childhood-onset motor disorder DYT6 dystonia is caused b

234 ature and should be reclassified as an early-childhood-onset neurodevelopmental condition in DSM-5.

235 tarting at age >/=18 years) as compared with childhood-onset severe asthma (<18 years) were selected

236 n patients with adult-onset as compared with childhood-onset severe asthma were identified in nasal b

237 Childhood-onset type 1 diabetes.

238 irth among cancer survivors diagnosed during childhood or adolescence; men were particularly vulnerab

239 with hypomagnesemia and/or hypocalciuria in childhood or adulthood).

240 Adjustment for childhood or current pet keeping did not alter associati

241 tudies have assessed the association between childhood organochlorine (OC) exposure and adult semen p

242 er Asthma and Allergy Study [n = 30] and the Childhood Origins of Asthma Study [n = 28]) was analyzed

243 Children enrolled in the Childhood Origins of ASThma study were followed prospect

244 sults extend previous work done primarily on childhood outcomes and suggest that protective associati

245 nce of early ischemic stroke associated with childhood overweight and obesity, these results suggest

246 Both being born LGA and childhood overweight may influence the development of as

247 In childhood, partial hearing loss can produce prolonged de

248 infant (<4.3 years; MBSHH-Infant; n=65) and childhood patients (>/=4.3 years; MBSHH-Child; n=38).

249 nce and IPD incidence prior to and following childhood PCV immunization in South Africa.

250 y, especially in the vulnerable neonatal and childhood periods.

251 Breastfeeding duration did not predict childhood PFAS concentrations in adjusted multivariable

252 The full extent to which childhood pneumococcal conjugate vaccines (PCV) can indi

253 The future of childhood pneumonia etiology research will likely requir

254 heless, accurately determining the causes of childhood pneumonia has remained elusive.

255 ates of pneumococcal pneumonia prevalence in childhood pneumonia studies.

256 d a marked impact on the incidence of severe childhood pneumonia.

257 sk factor for asthma, eczema, and allergy in childhood pointing toward in utero immune programming of

258 se; however, height-regulating processes in childhood present new areas for mechanistic explorations

259 and the immune system makes it possible for childhood psychosocial stressors to affect immune system

260 ternational Study of Asthma and Allergies in Childhood questionnaires.

261 c Migraine type 2, Alternating Hemiplegia of Childhood, Rapid-onset Dystonia Parkinsonism, or epileps

262 The pathogenesis of severe asthma in childhood remains poorly understood.

263 gene FIGF (c.352 G>A) associated with early childhood respiratory deficiency.

264 gnancy may play a role in the development of childhood retinoblastoma.

265 Lower childhood SEP was associated with higher adult BMI in bo

266 A between-pair effect of childhood social class was significant in all cognitive

267 porting the relative importance of the early childhood social environment.

268 1 may be an effective treatment strategy for childhood soft tissue sarcoma.

269 DNA transposase expressed in the majority of childhood solid tumors, including lethal rhabdoid tumors

270 is article looks at both nutrition and early childhood stimulation interventions as part of an integr

271 in children who stutter demonstrates that in childhood stuttering, atypical functional organization f

272 logy, the nature of the relationship between childhood symptoms and the underlying neurodevelopmental

273 Childhood TB diagnosis is challenging.

274 th of a mother, a father, and a sibling from childhood through midlife.

275 t detectable at appreciable levels in normal childhood tissues.

276 as brain function and behavior improve from childhood to adulthood?

277 time that gray matter density increases from childhood to young adulthood, in contrast with gray matt

278 For men, all forms of childhood trauma were associated with all forms of intim

279 ner violence or non-partner sexual violence, childhood trauma, and harsh parenting (smacking their ch

280 derstand and treat psychopathology linked to childhood trauma.

281 ent and treat psychopathology emerging after childhood trauma.

282 shire, United Kingdom, case-control study of childhood type 1 diabetes (1993-1994) in order to examin

283 Rate ratios of hospitalization in early childhood until 5 years of age.

284 sociation between parental separation during childhood (up to 18 years of age) and cardiometabolic ri

285 ially reduced prescribing of antibiotics for childhood upper respiratory tract infections.

286 Universal childhood vaccination is a potential solution to reduce

287 Routine childhood vaccination is declining in some regions of th

288 on of removing personal belief exemptions of childhood vaccination.

289 xplained by cognitive deficits that predated childhood victimization and by confounding genetic and e

290 Individuals exposed to childhood victimization had pervasive impairments in cli

291 m apart suggest that the association between childhood violence victimization and later cognition is

292 Individuals reporting a history of childhood violence victimization have impaired brain fun

293 To investigate the distribution of childhood visual function in the United Kingdom and asso

294 family-level fixed effects, maternal GWG and childhood weight gain are associated with adult body siz

295 PedsQL domains in childhood were equal to controls (P = NS), except for pr

296 de exposure in utero, during infancy, and in childhood were negatively associated with pubertal stage

297 Maternal stress, depression, and childhood wheezing episodes were assessed by quarterly q

298 Symptoms of ASD typically occur during early childhood, whereas most symptoms characteristic of schiz

299 s substantially outpaced gains in BMC during childhood, which could contribute to fracture risk.

300 with life-limiting conditions living beyond childhood, which means they must make the transition fro