ライフサイエンスコーパス: chimera

1 known as PROTACs (for 'proteolysis-targeting chimeras').

2 removes PCR-mediated recombinant sequences (chimeras).

3 erest in further experimental studies on the chimera.

4 nding site or via generation of an IgG1/IgG3 chimera.

5 ng peptide (GBP) as a dual-affinity biobrick chimera.

6 onately affected developing tissues within a chimera.

7 n O-permeabilized cells; so does a Rab3A-22A chimera.

8 ulted in a fully mature and active SKI-1/S1P chimera.

9 ly few studies have focused in detail on the chimera.

10 eves the cellular oncogenic addiction to MLL chimeras.

11 SD group, shorter RTs were observed for both chimeras.

12 ulating CD8 T cells in the mixed bone marrow chimeras.

13 ce and mixed wild-type:PLZF(-/-) bone marrow chimeras.

14 loid development using a series of radiation chimeras.

15 B cells in GC responses in mixed bone marrow chimeras.

16 yst injection, generating germline-competent chimeras.

17 ventral trunk are a common feature of mouse chimeras.

18 kling, inflammation and tissue damage in SCD chimeras.

19 e clonotypic iNKT cells using TCR retrogenic chimeras.

20 y 37% and 60%, respectively, in DC-LMP1/CD40 chimeras.

21 cytometry analyses in mixed bone-marrow (BM) chimeras.

22 protein profiling and proteolysis-targeting chimeras.

23 philia compared to CD40wt/Ldlr(-/-) (CD40wt) chimeras.

24 were found in the fetuses of tetraploid ESC chimeras.

25 ts, we analyzed a series of Orai mutants and chimeras.

26 For chimera 1, 1 of 9 seroconverted (the seroconverter recei

27 Seven subjects receiving chimera 2 or 4 had detectable CD8(+) T-cell responses to

28 For chimera 2, 3 subjects seroconverted (1 received 100 PFU,

29 Additional human trials of chimeras 2 and 4 are appropriate.

30 For chimera 3, none of 9 subjects seroconverted.

31 For chimera 4, 7 subjects seroconverted (1 received 10 PFU,

32 7% similarity, and removal of singletons and chimeras, a total of 2741 (V4) and 2606 (V8-V9) operatio

33 The chimeras accepted donor skin grafts and promptly rejecte

34 rans, Trans-ABySS and Trinity produced fewer chimeras across all single k-mer assemblies.

35 ntification of cell lines susceptible to VSV chimeras allowed us to recover recombinant HL17NL10 and

36 rotrimer (GT*) comprising a GalphaT/Galphai1 chimera (alphaT*) and beta1gamma1 The complex was formed

37 virus hemagglutinin fusion peptide, and this chimera also activates Ca(2+)-triggered fusion.

38 The SCZ glial chimeras also showed delayed astrocytic differentiation

39 binding nucleic acid or nucleic-acid-peptide chimera) alters the location of an attached redox report

40 ological levels of suPAR, as evidenced by BM chimera and BM ablation and cell transfer studies.

41 Double fluorescence in the G85R SOD1FP chimera and observation of the temporal development of f

42 es to HSV-1 were dissected using bone marrow chimeras and adoptive cell transfer approaches to profil

43 Using mixed bone marrow chimeras and adoptive transfer studies in which CD8 T ce

44 ations presented by intra- and inter-species chimeras and consider their future contribution to the s

45 Engraftment was durable in the majority of chimeras and increased over time.

46 selectivity we generated a series of P2X7/1R chimeras and mutants.

47 nscriptome assembly base coverage, number of chimeras and number of recovered full-length transcripts

48 development in limited-dilution bone marrow chimeras and show that higher TCR avidity correlates wit

49 sequence modifications, including loop-swap chimeras and single-residue mutations distributed throug

50 and desensitization through the analysis of chimeras and the assessment of the effect of covalent mo

51 a specific group of target genes of the MLL chimeras and their oncogenic cofactor, the super elongat

52 (Zika virus and Japanese encephalitis virus chimera), and the VRC 320, done in one centre, assessed

53 tyrosine kinase receptor B protein (TrkB-Fc) chimera, and (5) acute carbon monoxide poisoning followe

54 ransgenic mice, MAIThighHLA-DR4+ bone marrow chimeras, and humanized NOD-scid IL-2Rgammanull mice to

55 vesicular stomatitis virus, alphavirus-based chimeras, and measles vaccine Schwarz strain (MV/Schw) h

56 optive transfer, transgenic, and bone marrow chimera approaches to show increased infiltration and pr

57 truct a mapping of the vertex model into the Chimera architecture of the D-Wave machine, initiating a

58 Most (93%) of these well-localizing chimeras are also functional light-gated channels.

59 controls, and striatal neurons in mHTT glial chimeras are hyperexcitable.

60 Our studies demonstrate that these chimeras are viable and suggest that such recombinant vi

61 Chimeras are widely acknowledged as the gold standard fo

62 nditional Blimp-1 knockout mixed bone marrow chimera as well as an adoptive transfer approach, we sho

63 e feasibility of using the amyloidogenic RF1 chimeras as a reliable, rapid and cost-effective system

64 with A16, B04, B14, and B52 viruses or their chimeras, as measured by NF-kappaB (p65/Rel) translocati

65 In mixed-bone marrow chimera assays, we found that CCR4-deficient Treg and CC

66 ween different LRRC8 heteromers, we now used chimeras assembled from isoforms LRRC8C and LRRC8E to un

67 n (ACP) domain of the upstream module in one chimera at a residue predicted to influence ketosynthase

68 Chimeras bearing the HN protein derived from thermostabl

69 anosensitive module based on expression of a chimera between a pore-forming domain of the mechanicall

70 Reciprocal radiation chimeras between B6.C3-Bbaa1 and C57BL/6 mice revealed t

71 Bone marrow (BM) chimeras between C1qa(-/-) and WT mice identify non-BM-d

72 These double-stranded probes are chimeras between pseudocomplementary DNA (pcDNA) and Inv

73 Three of these 30 PG9 chimeras bound to the HIV-1 gp120 monomer, and two were

74 of glia to HD, we established human HD glial chimeras by neonatally engrafting immunodeficient mice w

75 Instead, a crystal structure of the ChR chimera (C1C2), an engineered combination of helices I-V

76 4 in lung protection, using used bone marrow chimeras; cell-specific transgenic modeling; and lentivi

77 Here, we show that the ESCRT-II/III chimera, Chm7, is recruited to a nuclear envelope subdom

78 xpression and localization data from 218 ChR chimeras chosen from a 118,098-variant library designed

79 NT group, no RT advantage was found for the chimeras compared to strings: both sets of features had

80 expressing a full-length dystrophin/utrophin chimera completely lacking microtubule binding activity

81 Mixed bone marrow chimeras, conditional knockout mice, and adoptive transf

82 Finally, we generated a GLUT7-GLUT5 chimera consisting of the N-terminal part of GLUT7 and t

83 A chimera consisting of Ypt1 with the switch I domain of S

84 Experiments on 25 chimeras, constructed from Kv1.2 and Kv2.1, showed that

85 Using alphaS/betaS domain-swapped chimera constructs and single residue substitutions in b

86 sis, purification, and characterization of a chimera containing part of the voltage sensor domain 2 (

87 Of the constructs tested, chimeras containing EIIIs from Koutango virus (KOUV), Ja

88 We were able to obtain viable chimeras containing the entire SARS-CoV M protein as wel

89 When expressed in E.coli, chimeras containing up to ~90% NUDT9H sequence remained

90 ary infection or intravenously injected with chimera-containing serum for passage infection.

91 refined approach to generating interspecies chimeras could contribute not only to a better understan

92 in vivo chimeric and survival capacities of chimeras created by injecting tetraploid embryonic stem

93 tibodies (solanezumab, crenezumab, and their chimera, CreneFab).

94 As expected, DC-LMP1/CD40/Ldlr(-/-) chimeras (DC-LMP1/CD40) showed increased antigen-present

95 based on self-assembling DNA-small molecule chimeras (DCs) that is capable of converting a chosen bi

96 r-deficient (vdr(-/-)) radiation bone marrow chimeras demonstrate that reductions in pulmonary TB imm

97 One ZFP-PB and one TALE-PB chimera demonstrated notable HPRT gene targeting.

98 ive B-1 cells expressed PD-L2 and irradiated chimeras demonstrated that B cell-intrinsic PD-L2 expres

99 Radiation chimeras demonstrated that MCPIP1 in nonhematopoietic ce

100 of HeLa cells with fluorescently labeled PMO chimeras demonstrated that these analogues were efficien

101 The use of bone marrow chimeras determined that deletion of caspase-12 in the r

102 Moreover, DC-LMP1/CD40 chimeras developed inflammatory bowel disease characteri

103 In contrast, Cas9/dCas9-PB chimeras did not result in gene targeting.

104 Importantly, this chimera, DII S1-S4, forms functional sodium channels and

105 In mixed bone marrow chimeras, Dpy30-deficient HSCs cannot differentiate or e

106 Analysis of selected bimodular chimeras, each with the same upstream module, revealed t

107 tral shift between emissions of the two iRFP chimeras enables combined multicolor bioluminescence ima

108 bly, all affinity losses were rescued in DAT chimeras encoding both SERT N and C termini.

109 i linear peptide chimera/recombinant modular chimera), engineered to express several autologous T cel

110 The SARS-CoV M chimera exhibited a conditional growth defect that was p

111 c bacterium Thermobifida fusca The resultant chimera exhibited activity levels similar to the wild-ty

112 Finally, bone marrow chimera experiments demonstrated that Ifitm3 functioned

113 Bone marrow chimera experiments indicated that the observed enhanced

114 In addition, competitive bone marrow chimera experiments reveal that RasGRP1/3 double-deficie

115 Bone marrow chimera experiments revealed a T cell-autonomous selecti

116 Mixed bone marrow chimera experiments showed this paucity to be intrinsic

117 We show through mixed bone marrow chimera experiments that NKT17 polarization is mediated

118 Bone marrow chimera experiments using OVA-treated C57BL/6 and TLR2(-

119 development of progenitor cells using mixed chimera experiments.

120 lowest-expressing parent; 12% of the tested chimeras express at even higher levels than any of the p

121 The majority of the chimeras express, with 89% of the tested chimeras outper

122 Significantly, a chimera expressing the simulans Shadow domain in a melan

123 In experiments with bone marrow chimeras, expression of BCL3 by acinar cells, but not my

124 cient hematopoietic cells, using bone marrow chimeras, failed to rescue the phenotype of decreased th

125 diate entry, even though the ch14.18 scFv-gD chimera Fc bound to neuroblastoma cells expressing GD2.

126 HNF1A(-/-) bone marrow chimera featured a dramatic defect in B lymphopoiesis re

127 Using a DC-SIGN-Fc chimera, food extracts were tested for binding by ELISA

128 mbryonic chimeras, including region-specific chimeras, for basic developmental biology research and r

129 From these analyses, we demonstrate PCR-chimera formation during PCR amplification and reference

130 whether human PSCs (hPSCs) can contribute to chimera formation in non-rodent species remains unknown.

131 m through the identification of miRNA-target chimeras formed by endogenous ligation reactions.

132 ld-type MLL protein, which displaces the MLL chimera from some of its target genes and, therefore, re

133 o create a large set of functionally diverse chimeras from three sequence-diverse channelrhodopsins (

134 We chose 218 ChR chimeras from two SCHEMA libraries and assayed them for

135 Mixed BM chimeras further revealed that CB2-expressing cells cont

136 Subsequent analysis of radiation chimeras generated from wild-type and Relb(-/-) bone mar

137 e different factors that affect interspecies chimera generation, such as evolutionary distance, devel

138 Our embedding on the Chimera graph preserves the structure of the original SC

139 k-SAT problems (and weighted max k-SAT) to a Chimera graph, which is the non-planar hardware graph of

140 m near the Shannon limit, can be mapped to a Chimera graph.

141 iability problem may be directly mapped to a Chimera graph.

142 e type restricted Ising Hamiltonian based on Chimera graphs.

143 tration, or the immune profile, although Noe chimera had more IFN (interferon)-gamma-producing NK cel

144 horodiamidate morpholinos (PMOs) and PMO-DNA chimeras have been prepared on DNA synthesizers using ph

145 These chimeras have catastrophe frequencies similar to that of

146 Many chimeras have stronger light-activated inward currents t

147 recruitment of beta-arrestin 2 to a GPR27V2 chimera in the presence of membrane-anchored G protein-c

148 tors involved in gH/gL trafficking, a CMV gH chimera in which the gH transmembrane and cytoplasmic ta

149 A chimera in which the MYO3A tail was fused to the MYO3B m

150 Regional expression of Venus-dysferlin chimeras in A/J fibres restored the full amplitude of th

151 By expressing AsLOV2 chimeras in Neuro2a cells, we achieved light-dependent m

152 Characterization of the chimeras in vitro and in vivo revealed differences in gr

153 echnical and ethical demands of experimental chimeras, including human-interspecies chimeras, they ar

154 approach could broaden the use of embryonic chimeras, including region-specific chimeras, for basic

155 , catalytic-site changes and an interspecies chimera indicate that pneumococcal MltG is the functiona

156 graphs and biochemical data with a PFKL/PFKP chimera indicate that the PFKL regulatory domain mediate

157 icroenvironment, and analysis of bone marrow chimeras indicated that the MZ B cell development defect

158 -measured reproductive skew in the spores of chimeras indicates strong social antagonism that should

159 -4A/GBV-B chimeric viruses and established a chimera-infected marmoset model.

160 The chimera-infected marmosets described can be used as a su

161 Six of seven HCV NS2 to -4A chimera-infected marmosets exhibited consistent viremia

162 HCV NS2 to -4A chimera-infected marmosets provide a small-animal model

163 facilitated the establishment of persistent chimera infection in marmosets.

164 nt domain residues in solanezumab/crenezumab/chimera influence the binding of Abeta aggregates.

165 The chimera is able to inhibit EGFR and survivin simultaneou

166 vidence that elimination of one partner in a chimera is an immune cell-based rejection that operates

167 This pore-domain chimera is permeable to Na(+), K(+), and Ca(2+) ions, an

168 However, chimera levels fluctuate in response to microtubule dyna

169 loy other measures of coherence, such as the chimera-like chi and metastability lambda indices, which

170 ults suggest that under certain assumptions, chimera-like states are prominent phenomena in modular n

171 ng can shape the dynamics in such a way that chimera-like states can happen.

172 parallel, Mertk(-/-)/Mfge8(-/-) bone marrow chimeras manifested increased accumulation of apoptotic

173 Bone marrow (BM) chimera mice revealed that mucosal repair depended on TN

174 Wild-type-->Tnfr1/2(-/-) BM chimera mice with chronic dextran sodium sulfate colitis

175 In a third chimera, mitochondrial mCherry did not transfer to G85R

176 type (WT) mice, and in mixed WT:BCAP(-/-) BM chimeras, monocytes and neutrophils skewed toward BCAP(-

177 choline-binding protein (AChBP), a humanized chimera of a snail AChBP, which has 71% sequence similar

178 In a chimera of ChAT promoter-EGFP and mito-mCherry, EGFP eff

179 y one histone H2A variant (H2AV), which is a chimera of H2AZ and H2AX.

180 xPx inhibited primary cilium enrichment of a chimera of rhodopsin and somatostatin receptor 3, where

181 using AS04-adjuvanted vaccines based on VLP chimeras of L1 with one or two L2 epitopes.

182 enesis in vivo, by testing the effect on the chimeras of natural polyphenols with known anti-amyloido

183 Chimeras of nonpathogenic wtSOD1YFP and G85R SOD1CFP als

184 segment to cMLCK activity were analyzed with chimeras of skMLCK and cMLCK.

185 Using HIV-2 chimeras of susceptible and nonsusceptible viruses, we s

186 Chimeras of TCL and TC10 revealed amino acids 121-129 of

187 Various chimeras of VACV-A6 and YLDV-97 were constructed, but on

188 of attenuation whereas other designs create chimeras of viral genomes.

189 pitation (CLIP) and ligation of miRNA-target chimeras on the Argonaute (AGO) protein to globally map

190 ng, using our newly developed rhodopsin-A2AR chimeras (optoA(2A)R).

191 We generated irradiation chimeras, or carried out adoptive transfers, with wild-t

192 the chimeras express, with 89% of the tested chimeras outperforming the lowest-expressing parent; 12%

193 gh the analysis of thousands of reproducible chimeras, pairing to the miRNA seed emerged as the predo

194 Finally, we present a simplified method, chimera PCR (ChimP), for the detection of specific miRNA

195 In human artery-SCID chimeras, PD-1 blockade exacerbated vascular inflammatio

196 e GLP-1R have utilized mutagenesis, receptor chimeras, photo-affinity labeling, hydrogen-deuterium ex

197 , the TVA did not respond more to artificial chimeras preserving the exact spectral profile of voices

198 t the development of a proteolysis targeting chimera (PROTAC) based on the combination of the unique

199 esigned based upon the proteolysis targeting chimera (PROTAC) concept to induce BET protein degradati

200 Proteolysis Targeting Chimera (PROTAC) technology is a rapidly emerging altern

201 -BET degrader based on proteolysis-targeting chimera (PROTAC) technology, demonstrates dramatically i

202 Proteolysis targeting chimeras (PROTACs) are bifunctional molecules that recru

203 Proteolysis targeting chimeras (PROTACs) are bispecific molecules containing a

204 tionally, bifunctional proteolysis targeting chimeras (PROTACs) containing a VHL ligand can hijack th

205 f small-molecule-based proteolysis-targeting chimeras (PROTACs) have demonstrated that this technolog

206 The design of proteolysis-targeting chimeras (PROTACs) is a powerful small-molecule approach

207 Our chimera protein may thus represent a simple molecular fu

208 centration results in a polarized pattern of chimera proteins with a spatial extension that is very r

209 Chimeras provide convenient soluble NUDT9H models for st

210 Experimental chimeras provide key insights into mammalian development

211 ecombinant protein (P. yoelii linear peptide chimera/recombinant modular chimera), engineered to expr

212 lts, and Rag2(-/-) gammac(-/-) hematopoietic chimeras reconstituted with cd69(-/-) stem cells.

213 ic IgM, naive PD-L2(-/-) mice and irradiated chimeras reconstituted with PD-L2(-/-) B cells had signi

214 In chimeras, regulation could be conferred to a foreign ect

215 ipotent stem cells (hPSCs) to form embryonic chimeras remains in question.

216 erns that seem to underlie this research and chimera research more generally can be adequately addres

217 ing NUDT9H in full-length TRPM2 with soluble chimeras retained ADPR-dependent channel gating (K1/2~1-

218 s based on the crystal structure of a Kir3.1 chimera revealed the possible gating mechanism of the G

219 Human-rat transporter chimeras revealed that human URAT1 serine-35, phenylalan

220 Other experiments with bone marrow chimeras revealed that inflammation was not the primary

221 Bone marrow chimeras revealed that TLR4 expression on hematopoietic

222 Characterization of E1 chimeras revealed that, while the function of the AR cou

223 Chimeras reversing patterns of disorder in Nbs1 reversed

224 culated intrahepatically with HCV NS2 to -4A chimera RNA for primary infection or intravenously injec

225 r the recovery of replication fitness in the chimera RNA.

226 n the DENV2 NS3 helicase domain in the DENV2 chimera RNAs by repeated passaging of infected BHK-21 or

227 The reciprocal chimera (Rx1CN/Gpa2L) shows a loss-of-function phenotype

228 ibitor (MZ242) and its proteolysis targeting chimera (SH1) acting together with TPPP/p25 provoke micr

229 Bone marrow chimeras showed that bone marrow-derived cells contribut

230 Bone marrow chimeras showed that Mif expression in bone marrow-deriv

231 Our studies with ASIC1a-ASIC2a chimeras showed that swapping the thumb domain between s

232 Bone marrow chimeras showed that the anti-inflammatory role of NLRP1

233 Transfer of platelets into Hmgb1(-/-) chimeras showed that this cell type is the major source

234 icular infusion of recombinant human TrkB-Fc chimera significantly blunted the protection by the hype

235 PCa xenograft model, the treatment with the chimera significantly suppresses tumor growth and angiog

236 Chimera states, namely the coexistence of coherent and i

237 These include chimeras, structural errors, incomplete assembly, and ba

238 Further, animal chimera studies demonstrate that wild-type endoderm cell

239 Data from our chimera studies demonstrated that IL-1beta produced by h

240 doptive reconstitution and mixed bone-marrow chimera studies in B cell-deficient (microMT) mice, we r

241 gratory DCs (mDCs) present in LNs, and mixed-chimera studies revealed that this migratory defect was

242 Consistent with this, bone marrow chimera studies show that aberrant Pkhd1 must be express

243 responses, and lipid uptake, and bone marrow chimeras suggest that hematopoietic EphA2 deletion does

244 nal deletion was detected in host T cells in chimeras, suggesting central tolerance to donor alloanti

245 thermore, the analysis of experimental mouse chimeras suggests a cell-extrinsic role of Pax6 in CN ne

246 ency to T cells by using a mixed bone marrow chimera system and found that T-cell-intrinsic Trim24 is

247 nge in B-1a cell IgM, we established a mixed chimera system in which mice were reconstituted with all

248 The RNAi scaffold is a general utility chimera that contains a functional RNA duplex with paire

249 yonic chimeras, thereby forming interspecies chimeras that could survive to adulthood.

250 ipoprotein-deficient (Ldlr(-/-)) bone marrow chimeras that express a transgene containing an engineer

251 er parts with real floral organs, we created chimeras that identified the mushroom-like labellum as a

252 pinnings of this effect, we created auditory chimeras that retained only the temporal or the spectral

253 characterization identified multiple active chimeras that showed improved nitration activity, increa

254 Within the chimera, the Tsr HAMP undergoes a thermal melting transi

255 rat EpiSCs to contribute to mouse embryonic chimeras, thereby forming interspecies chimeras that cou

256 ental chimeras, including human-interspecies chimeras, they are a provocative resource for achieving

257 tructure-based mutations and WASP-Arp fusion chimeras to determine how WASP stimulates movement towar

258 on, we expressed truncated forms and protein chimeras to gain a deeper understanding of toxin specifi

259 In this study, we use bone marrow chimeras to show that clinical and histological inflamma

260 rgeting various dyes and fluorescent-protein chimeras to vesicles, the plasma membrane, as well as mi

261 In mixed bone marrow chimeras, Tpl2 was shown to play a T cell-intrinsic role

262 cal algorithm, MACHETE (Mismatched Alignment CHimEra Tracking Engine), which achieves highly sensitiv

263 Similar to CXCL10(-/-) mice, chimeras unable to express CXCL10 in hematopoietic-deriv

264 By creating chimeras using the extracellular and intracellular domai

265 The Towne/Toledo chimera vaccine candidates were well tolerated and were

266 ain were recombined, yielding 4 Towne/Toledo chimera vaccines.

267 Substrate promiscuity of the most active chimera was further assessed with a substrate library.

268 Although this chimera was inactive, we demonstrate fructose transport

269 es APOBEC3B and creates an APOBEC3A-APOBEC3B chimera was not important in bladder cancer, whereas it

270 rabinose-inducible, rapidly folding OmpA-GFP chimera was utilized to jam the SecYEG channels with an

271 ion properties, a set of TAL claudin protein chimeras was created and analyzed.

272 To identify low KM chimeras we developed a suitable bacterial selection sys

273 Using genetic chimeras we show that Bmp signals directly to the endode

274 Furthermore, using bone marrow chimeras we show that deletion of AhR in the immune syst

275 In addition, using bone marrow chimeras, we demonstrate that PVM are the cells expressi

276 y with DREAM-null mice and their bone marrow chimeras, we demonstrated that both hematopoietic and no

277 ter/fate mapping mice, and mixed bone marrow chimeras, we identified two distinct populations of NK c

278 During study of both the SOD1FP and EGFP chimeras, we observed fluorescence also in small cells n

279 Using radiation chimeras, we were able to rule out a requirement for IL-

280 Additionally the N,N-dimethylamino PMO-DNA chimeras were found to stimulate RNaseH1 activity.

281 ryonic tissues and fetuses of tetraploid ESC chimeras were tetraploid as determined by fluorescence a

282 wild-type littermates, or mixed bone marrow chimeras were treated with the protease allergen papain

283 cells, such as EpiSCs, fail to contribute to chimeras when injected into pre-implantation-stage blast

284 ed the crystal structures of PilM and a PilM chimera where PilM was fused to the first 12 residues of

285 A primase chimera, where PriX is fused to a truncated version of P

286 -activated potassium channels, we engineered chimeras wherein transmembrane regions of TRPV1 were tra

287 We also used "auditory chimeras", which preserved subsets of acoustical feature

288 Moreover, IGPR-1 chimera, which mimics the trans-homophilic dimerization

289 A chimera with replacement of the human NTD by the bovine

290 ecific sialyltransferase (ST) expressed as a chimera with the rapamycin-binding domain of mTOR, FRB,

291 The creation of a NaV1.7-NaVAb chimera with the VSD2 toxin binding site provides an imp

292 CY, without TBI or fludarabine, led to mixed chimeras with 81.3 +/- 10.6% mean donor origin CD8(+) ce

293 oxin genes from B. thuringiensis and created chimeras with differing properties that can help us unde

294 decided to humanize gpASNase1 by generating chimeras with hASNase1 through DNA shuffling.

295 hiPSCs and hESCs form interspecies chimeras with high efficiency, colonize the embryo in a

296 ng the properties of homologously recombined chimeras with one or two crossovers is also an efficient

297 surrogate target strategy approach employing chimeras with the bacterial channel NaVAb.

298 Crystal structures of 14-3-3 chimeras with three different peptides provide detailed

299 rophyte plastid proteome was an evolutionary chimera, with 25% of its phylogenetically tractable nucl

300 Although many chimeras yielded detectable products, nearly all had spe