ライフサイエンスコーパス: chimeric gene

1 rum-starved fibroblasts transfected with the chimeric gene.

2 ome translocation that generates the bcr-abl chimeric gene.

3 flanking region eliminated expression of the chimeric gene.

4 he adenovirus-2 VA RNAI promoter in a VA-Tat chimeric gene.

5 polyadenylation site was identified using a chimeric gene.

6 the SA-inducibility of a truncated PR-2d:GUS chimeric gene.

7 rtship behaviors by the recruitment of a new chimeric gene.

8 confirmed with cells expressing a VNX1::GFP chimeric gene.

9 ylyl transferase 1 (Nmnat-1)/truncated-Ube4b chimeric gene.

10 bserved with the recombinant carrying a G/HA chimeric gene.

11 closely related homolog, generating a novel chimeric gene.

12 recognized as a 3'-end formation element in chimeric genes.

13 h HLA-DRA-IE alpha and HLA-DRB1*0401-IE beta chimeric genes.

14 eading to duplications, deletions, and novel chimeric genes.

15 A chimeric gene 4 protein containing the acidic C terminus

16 id leukemia results in the expression of the chimeric genes AML1/EAP, AML1/MDS1, and AML1/EVI1.

17 We have made chimeric genes among Y1, Y3, Y4 and Y5 and examined thei

18 anti-Igkappa-reactive single chain antibody chimeric gene and expressed it as a transgene in mice.

19 One-third of these genes are chimeric genes and their sequences suggest that the porc

20 which leads to expression of the DEK-NUP214 chimeric gene, and has a particularly poor outcome.

21 Chimeric genes appear, and occasionally are differential

22 f reciprocal hybrids, we concluded that some chimeric genes are present in the genome and are not PCR

23 led to the application of a HIV-1 gp160/LAMP chimeric gene as a novel means to enhance the MHC II pre

24 ugh unequal crossovers, which have generated chimeric genes as well as variations in copy number.

25 ntal Landsberg erecta line and expressed the chimeric gene, as indicated by detection of its mRNA by

26 , ATCNGC11 and ATCNGC12, to generate a novel chimeric gene, ATCNGC11/12.

27 uffling generates combinatorial libraries of chimeric genes by stochastically recombining parent gene

28 The highly efficient generation of mutant or chimeric genes by this method can easily be accomplished

29 Chimeric genes can be caused by structural genomic rearr

30 In addition, both the SRF and MEF2 chimeric genes can complement the pertinent ap1-1, ap3-3

31 Together, these results show that chimeric genes can produce structural and regulatory cha

32 ceptor on the cell membrane, we engineered a chimeric gene coding for amino acids 1 to 151 of CD14 fu

33 r modified for enhanced expression driving a chimeric gene coding for the soybean native amino-termin

34 vo, transgenic mice were generated bearing a chimeric gene composed of human surfactant protein C (SP

35 We have generated a chimeric gene composed of the frataxin gene fused with t

36 at any sequence location, creating "perfect" chimeric genes composed of DNA fragments that have been

37 Transgenic plants carrying chimeric genes composed of segments of the 5'-flanking r

38 rming either hybrid poplar or tobacco with a chimeric gene consisting of the 2.8 kb bspA promoter fus

39 In this study, poplars transformed with a chimeric gene consisting of the bspA promoter fused to b

40 e domain(s) that determines the differences, chimeric genes consisting of part mBE I and part mBE II

41 ion by analyzing the activity of a series of chimeric genes consisting of rat Col2a1 first intron del

42 ved by introducing into Arabidopsis plants a chimeric gene construct consisting of the firefly lucife

43 One chimeric gene construct supported growth on nonfermentab

44 Tobacco plants were transformed by using a chimeric gene construction, in which a corn sucrose synt

45 m of DC8 expression during seed development, chimeric gene constructs containing DC8 promoter fragmen

46 Full light regulation of chimeric gene constructs containing the cauliflower mosa

47 ormed lettuce cv. Diana (carrying Dm3) using chimeric gene constructs designed to simultaneously sile

48 The chimeric gene constructs exhibited expression of the rec

49 is possibility the expression of a series of chimeric gene constructs in transgenic tobacco plants wa

50 en investigated using cells transfected with chimeric gene constructs in which globin reporter sequen

51 icle incorporation, we generated a series of chimeric gene constructs in which the coding sequences f

52 Analysis of chimeric gene constructs localized the regions dependent

53 Analyses of deletion and chimeric gene constructs of PPR2 implicate contributions

54 ompC-phoA chimeric gene constructs revealed a 248-bp untranslated

55 These chimeric gene constructs synthesized biologically active

56 The expression patterns of these chimeric gene constructs were evaluated both in transgen

57 tobacco plants harbouring ZmC5 promoter/GUS chimeric gene constructs.

58 A chimeric gene containing the Glaucoma chattoni TER1 tran

59 ion codons involves a common trans-factor, a chimeric gene containing the ndhD editing site was expre

60 ce the Met content in the transgenic plants, chimeric genes containing four mutant constructs, BoxIa

61 for their role in C-->U editing by designing chimeric genes containing one or more of these divergent

62 eterminants of Sis1 function, we constructed chimeric genes containing portions of SIS1 and YDJ1.

63 Chimeric genes containing portions of the mouse myelin p

64 n, we have stably transfected HTC cells with chimeric genes containing sequences from the rat PAI-1 c

65 nction of the Ron gene promoter, a series of chimeric genes containing serial deletions of the Ron ge

66 ene was assessed by transiently transfecting chimeric genes containing the beta1-AR promoter, driving

67 ate genes within the genome and suggest that chimeric genes contribute substantially to genomic novel

68 decades to be the translational product of a chimeric gene created by the stable chromosome transloca

69 AML1-ETO is the translational product of a chimeric gene created by the stable chromosome transloca

70 at seven sites, examined the quality of the chimeric genes created, and screened the library of 2(8)

71 221 and GP-CG32779, are pseudogenes, and the chimeric gene Crg1 is subject to balancing selection.

72 The 76 kDa protein product of the chimeric gene, designated bgt-trk, has been identified i

73 Two reciprocally chimeric genes, each containing the N terminus of one ma

74 ession in fibroblastic cells in mice using a chimeric gene encoding the Cre-ER(T) fusion protein, und

75 We generated a chimeric gene encoding the full-length rabbit 11beta-HSD

76 A chimeric gene encoding the lunasin peptide tagged with g

77 The result was a variety of chimeric genes encoding novel integral fusion proteins t

78 These rearrangements create chimeric genes encoding self-associating, constitutively

79 To this end, we constructed chimeric genes encoding the HIV envelope glycoproteins p

80 We constructed chimeric genes encoding the human immunodeficiency virus

81 Using chimeric genes encoding the luciferase reporter, we foun

82 We therefore constructed a chimeric gene ("ER/GR") containing the hormone-binding d

83 The chimeric gene EWS/FLI is present in at least 85% of Ewin

84 chromosomal translocations give rise to the chimeric gene EWS/FLI, encoding the N-terminus of the RN

85 The chimeric gene EWS/FLI-1, the hallmark of the Ewing's sar

86 rcomas, such translocations give rise to the chimeric gene EWS/FLI.

87 In PC12 cells transiently transfected with a chimeric gene expressing chloramphenicol acetyltransfera

88 um of GM-CSF-hull mutant mice (GM-/-) with a chimeric gene expressing GM-CSF under the control of the

89 del for plant mitochondrial DNA replication, chimeric gene formation, and the illegitimate recombinat

90 We propose two mechanisms of chimeric gene formation, which rely entirely on local, D

91 It is a chimeric gene formed by duplication of two other genes f

92 However, recent work suggests that chimeric genes formed through the fusion of pieces of di

93 er was composed of a silent DeltaRBCS1B::LUC chimeric gene fusion, lacking all 5' transcription and t

94 all main varieties of genetic abnormalities: chimeric gene fusions, copy number alterations, and sing

95 Fusion oncoproteins that arise from chimeric genes generated by such translocations are usua

96 ocess akin to replication slippage to form a chimeric gene in a single event.

97 o date, the translocation event results in a chimeric gene in which the atypical zinc-finger domain o

98 Transgenic mice, containing a chimeric gene in which the cDNA for phosphoenolpyruvate

99 re novel alcohol dehydrogenase (Adh)-derived chimeric genes in the Drosophila bipectinata complex.

100 by, directly oriented gene, predicting novel chimeric genes in these subjects' genomes.

101 protein (GFP) and transiently expressed the chimeric genes in tobacco leaves.

102 Be examining the expression of chimeric genes in transgenic tobacco, we demonstrate tha

103 vity of mutations of the E4 promoter, and of chimeric genes in transient assay.

104 that confer this specificity, we constructed chimeric genes in which 5.8 kb of 5' sequences of the II

105 or oxygen-regulated activity, we constructed chimeric genes in which portions of coding sequence from

106 ir biological specificity, we have generated chimeric genes in which the amino-terminal half of the M

107 We have constructed chimeric genes in which the sequences for the N and C-te

108 an in vivo stroma-targeting function, since chimeric genes in which the stroma-targeting domain of t

109 sfected C2C12 cells with mutant myc genes or chimeric genes in which various myc sequences were fused

110 cells where H2A.Y is depleted, an inducible chimeric gene, in which the H2A.Y N terminus is attached

111 transforming the 2.8 kb bspA-promoter::uidA chimeric gene into tobacco.

112 d by direct injection of promoter-luciferase chimeric genes into rat liver.

113 The NPM-ALK chimeric gene is an activated tyrosine kinase that has b

114 Expression of the PR-2d: uidA(GUS) chimeric gene is induced in leaves undergoing the hypers

115 Strikingly, this chimeric gene is now activated by the dpp enhancers.

116 The molecular origin of the BCR-ABL chimeric gene is now reasonably well defined; a new brea

117 The MLL-ELL chimeric gene is the product of the (11;19)(q23p13.1) tr

118 These results suggest that the formation of chimeric genes is a mechanism by which CNVs contribute t

119 Complementary chimeric gene libraries generated by incremental truncat

120 sperms, including Arabidopsis thaliana, this chimeric gene (named BIO3-BIO1) also produces a bicistro

121 the structure and placement of the youngest chimeric genes observed.

122 ensory organs in transgenic flies expressing chimeric genes of ato and scute (sc), a member of ASC, a

123 These chimeric genes often evolve rapidly, suggesting that the

124 The chimeric gene pABRE:NCED enhanced NCED and ABF (ABRE-bin

125 Studies of recently evolved chimeric genes permit direct investigation of the origin

126 The chimeric gene produced a high level of luciferase activi

127 TO (MTG8) on chromosome 8, and the resultant chimeric gene product, AML-1/ETO.

128 how this interaction could preserve ERV/host chimeric gene products affecting female fertility.

129 oplastic owing to constitutive expression of chimeric gene products normally generated by trans-splic

130 eukemias are associated with the presence of chimeric gene products that arise from spontaneous chrom

131 This chimeric gene provided near recessive null function in a

132 This chimeric gene provided wild-type function in the develop

133 Here, we describe the chimeric gene Quetzalcoatl (Qtzl; CG31864), which formed

134 125 to -100 to the -3311 beta1-AR/luciferase chimeric gene reduced expression in myocytes and SK-N-MC

135 However, ectopic expression of the chimeric genes reproduces the dominant gain-of-function

136 volutionary history of SETMAR, a new primate chimeric gene resulting from fusion of a SET histone met

137 ic RBCSB gene cluster to isolate recombinant chimeric genes resulting from meiotic recombination betw

138 When expressed in Xenopus oocytes, one chimeric gene (rho1/alpha1) formed functional homooligom

139 NA stability suggest that expression of this chimeric gene(s) may also be affected by rapid RNA degra

140 isolated by direct selection (1) contain the chimeric gene(s) stably integrated into the nuclear geno

141 Like other Adh-derived chimeric genes, siren evolved adaptively shortly after i

142 ere, we describe the phenotypic effects of a chimeric gene, sphinx, that has recently evolved in Dros

143 a nearby exon and intron, thereby evolving a chimeric gene structure.

144 n the Leu-rich repeat 2 region, resulting in chimeric gene structures.

145 3Delta mutation, expression of a human-yeast chimeric gene that contains 42% human sequences can part

146 Coinjection of the 51A gene with the chimeric gene that contains 51B up to +885 showed that t

147 two wild-type small-subunit genes or with a chimeric gene that contains features of both.

148 Using a chimeric gene that contains TCRbeta sequences conferring

149 th the coding sequence of FCGR2B, creating a chimeric gene that results in an ectopic accumulation of

150 ine independent intragenic mutations in this chimeric gene that suppressed the growth phenotype of ye

151 As the chimeric gene that we developed for these studies genera

152 taposition generates PAX3-FKHR and PAX7-FKHR chimeric genes that are expressed as chimeric transcript

153 Chimeric genes that contained at least 800 bp of TUB9 5'

154 Only those chimeric genes that contained the 3'-untranslated region

155 equired for these functions we tested eleven chimeric genes that contained variable amounts of Wnt-1

156 hromatids created an allelic series of novel chimeric genes that effectively resulted in the diversif

157 d by the breakpoint cluster region (BCR-ABL) chimeric gene, the product of which is p210BCR-ABL, a ty

158 ith 51B sequences (-1647 to +885) allows the chimeric gene to be coexpressed with 51B.

159 steocalcin promoter to confine expression of chimeric genes to bone.

160 However, the propensity of chimeric genes to produce adaptive phenotypic changes is

161 combinant adenovirus containing the U1b-lacZ chimeric gene transduced and expressed beta-galactosidas

162 e clinically because we were able to discern chimeric gene transfer in tumor-bearing animals with (11

163 the in vitro and in vivo detection of SSTR2 chimeric gene transfer with this radiopharmaceutical.

164 Remarkably, the chimeric gene Tre2 exists only in the hominoid lineage o

165 n reading frame/c-myc 3'-untranslated region chimeric gene under control of the c-fos promoter (fos-g

166 Effects on mRNA stability were assayed using chimeric genes under the control of the tetracycline-rep

167 E6 and E7 genes were cloned as U6/antisense chimeric genes under the control of the U6 RNA gene prom

168 codon bias and by driving expression of the chimeric gene using either of two C. reinhardtii chlorop

169 n of cationic liposome complexed with a CAII chimeric gene, using a cytomegalovirus (CMV) promoter/en

170 A chimeric gene was constructed from the genes coding for

171 y promoter/enhancer and a unique E4-ORF6/pIX chimeric gene was employed as the backbone vector.

172 -enhanced expression of 5'-Srglb3-uidA-3'nos chimeric gene was investigated in transgenic Nicotiana t

173 The TUB1 chimeric gene was preferentially expressed in epidermal

174 cal cells of primary roots, whereas the TUB8 chimeric gene was preferentially expressed in the endode

175 e tolerance to chloroacetamide herbicides, a chimeric gene was produced containing the open reading f

176 The recombinant chimeric gene was transfected into Chinese hamster ovary

177 dent, indicating that the RNA encoded by the chimeric gene was transferred to Vero cells as mRNA.

178 This chimeric gene was transformed into a photosystem I-less/

179 ng this system for efficient construction of chimeric genes was explored by constructing promoter::re

180 The in vivo function of these chimeric genes was investigated by ectopic expression in

181 Different expression levels of the chimeric gene were confirmed in vitro.

182 When cells rescued with the MTT1-GTU1 chimeric gene were transferred to medium lacking Cd(2+),

183 Sixteen AAC1/AAC2 chimeric genes were constructed and analyzed to determin

184 Two chimeric genes were constructed, made up of portions of

185 number of Dm3 paralogs was changed, no novel chimeric genes were detected.

186 The chimeric genes were found to show biases in the incorpor

187 led in vivo by homologous recombination, and chimeric genes were generated regardless of whether or n

188 The chimeric genes were introduced into CHO cells by stable

189 oding sequence of uidA reporter gene and the chimeric genes were introduced into transgenic tobacco p

190 ia and myelodysplastic syndrome, generates a chimeric gene where the 5' portion of the sequence encod

191 Chimeric genes which contained the mouse U1b snRNA promo

192 t, the rpp8 locus in Col-0 contains a single chimeric gene, which was likely derived from unequal cro

193 Chimeric genes, which form through the genomic fusion of

194 yielding a novel recombinant RBCS3B/ 1B::LUC chimeric gene whose expression was driven by RBCS3B 5' t

195 Libraries of chimeric genes with up to five crossovers were synthesiz