ライフサイエンスコーパス: chimeric mice

1 combined immune deficiency (uPA-SCID) mice" (chimeric mice).

2 rol mice, but not in WT or DREAM bone marrow chimeric mice.

3 topoietic cells was evaluated in bone marrow chimeric mice.

4 Wid-type, neogenin deficient and chimeric mice.

5 ection and subsequent demyelination of these chimeric mice.

6 and support the generation of teratomas and chimeric mice.

7 nal-associated Nlrp3 by studying bone marrow chimeric mice.

8 ying HBV-infected and uninfected human liver chimeric mice.

9 ells, as demonstrated with mixed bone marrow chimeric mice.

10 NTN was then investigated using bone marrow chimeric mice.

11 K cells similarly in young mixed bone marrow chimeric mice.

12 rtex, amygdala, and hippocampus of GFP(+) BM-chimeric mice.

13 type HSPCs proliferated in mixed bone marrow chimeric mice.

14 ifferentiated teratomas, and cannot generate chimeric mice.

15 L-10 receptor deletion mice, and bone marrow chimeric mice.

16 and the CNS during EAE, we used bone marrow chimeric mice.

17 SHIP-1(-/-) animals and disease induction in chimeric mice.

18 d in vitro and in vivo using NOX1 or NOX2 BM chimeric mice.

19 lls or nonhematopoietic cells in bone marrow chimeric mice.

20 hich encodes properdin) and by generating BM chimeric mice.

21 ly protective immune response in bone marrow chimeric mice.

22 irus dose is required to consistently infect chimeric mice.

23 eduction of plaque size in NK-cell-deficient chimeric mice.

24 rus-transduced mouse T cells and bone marrow chimeric mice.

25 infected mixed p50(+/+)/p50(-/-) bone marrow chimeric mice.

26 constitute T cell development in bone marrow chimeric mice.

27 tion and reactive neutrophilias in radiation chimeric mice.

28 on were observed between these transgenic or chimeric mice.

29 ity in vitro and in HBV-infected human liver chimeric mice.

30 en motor neurons could be detected in intact chimeric mice.

31 Rbeta(+/+) counterparts in mixed bone marrow chimeric mice.

32 macrophages differentiated from the BM of UV-chimeric mice.

33 lammatory compared to plaques of Trem-1(+/+) chimeric mice.

34 increased MDSC accumulation in the recipient chimeric mice.

35 s were performed in vitro and in human liver chimeric mice.

36 tween C57BL/6J and Vwf(-/-) mice to generate chimeric mice.

37 shed the HBV replication in human hepatocyte-chimeric mice.

38 opathology compared with wild-type (WT)-->WT chimeric mice.

39 ies in the human hepatocytes in FIAU-treated chimeric mice.

40 Our results with P2X7(-/-) bone marrow chimeric mice, adoptive transfer of peritoneal macrophag

41 CV infected (GT1a and GT3a) human hepatocyte chimeric mice after 7 days of oral administration of 9.

42 n of NOD ES cell lines capable of generating chimeric mice after stable genetic modification.

43 type, Cd39 ectonucleotidase-null mice and in chimeric mice after transplantation of wild-type or Cd39

44 Similarly, human hepatocytes in chimeric mice also gave rise to biliary progenitors in v

45 acrophages differentiating from the BM of UV-chimeric mice also had an inherent reduced ability to mi

46 effector responses in both mixed bone marrow-chimeric mice and adoptive cell transfer experiments.

47 Indeed, in chimeric mice and after adoptive transfer, wild type T c

48 e way for more widespread use of human liver chimeric mice and forms the basis for creating increasin

49 In vivo studies using bone marrow chimeric mice and in vitro studies of neutrophil activat

50 using B6/Langerin-diphtheria toxin receptor chimeric mice and LC ablation, we demonstrated that epid

51 ela(+/-) neutrophils in peritonitis in mixed chimeric mice and neutrophilia in Crel(-/-)Nfkappab1(-/-

52 els in adult green fluorescent protein (GFP) chimeric mice and oxygen-induced retinopathy in mouse pu

53 By generating chimeric mice and performing skin reconstitution assays

54 study, we used immune competent bone marrow chimeric mice and syngeneic orthotopic mammary cancer mo

55 on iNKT cells using germline-deficient mice, chimeric mice, and conditionally deficient mice.

56 ve erythroblasts develop normally in vivo in chimeric mice, and Hb Null erythroid cells undergo enucl

57 Human liver chimeric mice are a step forward in this regard, as the

58 for preclinical drug development.Human liver chimeric mice are increasingly used for drug testing in

59 die neonatally, but Orai1(KI/KI) fetal liver chimeric mice are viable and show normal lymphocyte deve

60 LTP) was sharply enhanced in the human glial chimeric mice, as was their learning, as assessed by Bar

61 e mAbs, K04, was administered to human liver chimeric mice before or after HCV infection to determine

62 Generation and immunization of reciprocal chimeric mice between BALB/c and B10.D2 strains revealed

63 -specific effects in vivo, we generated CD36 chimeric mice by bone marrow transplantation and evaluat

64 We generated CCR2 chimeric mice by the combination of clodronate, irradiat

65 VDR deficiency, we produced bone marrow (BM)-chimeric mice by transplanting lethally irradiated C57BL

66 In BM chimeric mice (C57BL/6 with tandem dimer Tomato-positive

67 Furthermore, chimeric mice can be generated by injecting these mESCs

68 Compared with control Ldlr(-/-) chimeric mice, CD11c-Cre x Tcf4(-/flox) mice had reduced

69 We then generated chimeric mice (Cdk5(+/+C) or Cdk5(-/-C)) using hematopoi

70 ificantly less than that measured in control-chimeric mice challenged with the same inflammatory agen

71 ection over the calvaria of NLRP12-deficient chimeric mice compared with wild-type control mice.

72 Bone marrow chimeric mice confirmed that CX3CR1 deficiency in bone m

73 Studies of OVA-treated Adam8 bone marrow chimeric mice confirmed that leukocyte-derived Adam8 pre

74 llin IgG levels were similar in both sets of chimeric mice, consistent with the equal participation o

75 However, chimeric mice containing both CTLA-4-deficient and -suff

76 ed increased macrophage recruitment, whereas chimeric mice containing CCR2(-/-) BM showed less macrop

77 We observed that chimeric mice containing Ifnar-deficient hematopoietic c

78 Chimeric mice containing wild-type BM displayed increase

79 Using chimeric mice containing wild-type or IL-21R(-/-) CD4 T

80 Using mixed chimeric mice, containing both wild-type and syk(f/f) MR

81 Bone marrow chimeric mice (Cxcr2(+/-)-->Cxcr2(-/-) and Cxcr2(+/-)-->

82 Reduced cardiac function was reproduced in chimeric mice deficient in bone marrow Mertk; reciprocal

83 The use of chimeric mice deficient in ICAM-1 on myeloid cells demon

84 Similar results were obtained in chimeric mice deficient in leukocyte TNF.

85 Using chimeric mice deficient in the KC receptor CXCR2 in thei

86 In contrast, chimeric mice deficient in TLR2 in the nonhematopoietic

87 on of cochlear tissue indicated that prestin chimeric mice demonstrate a mosaic in which mutant and n

88 SCs respond to TLR2 ligand, TLR2 bone marrow chimeric mice demonstrated that Kupffer cells were relat

89 Experiments conducted using bone marrow chimeric mice demonstrated that radio-resistant cells pa

90 The establishment of bone marrow chimeric mice demonstrated that the block in beta cell a

91 of wild-type x MyD88(-/-) mixed-bone-marrow chimeric mice demonstrated that there is a selective fai

92 ell transcription factor expression in mixed chimeric mice depended on neutrophil count, not iNKT cel

93 ts, our familial hypercholesterolaemia liver chimeric mice develop hypercholesterolaemia and a 'human

94 ter treatment with FIAU 400 mg/kg/d for 4 d, chimeric mice developed clinical and serologic evidence

95 Human liver-chimeric mice developed high-titer infections after inoc

96 that of IL-17RA(-/-) mice and of bone marrow chimeric mice devoid of IL-17 signaling in immune and Ku

97 Batf3(-/-) chimeric mice did not show lower Tcell or other leukocyt

98 n, naive CD4(+) T cells from USP9X knockdown chimeric mice display decreased cytokine production and

99 IFNAR KO Tregs from chimeric mice displayed a more naive phenotype, accompan

100 icient effector T cells in mixed bone marrow chimeric mice during a parainfluenza virus infection.

101 The MyD88(B-/-) chimeric mice exhibited an impairment of development of

102 TLR2 knockout (TLR2KO)-->TLR2KO bone marrow chimeric mice exhibited increased bacterial burden, diso

103 and brains after vaginal HSV-1 challenge of chimeric mice expressing both perforin and Fas or neithe

104 was investigated using bone marrow (BM) from chimeric mice expressing luciferase (Col-Luc-->wt) or gr

105 intrinsic because Irf4-deficient B cells in chimeric mice failed to participate in the GC in respons

106 ransplantation revealed more liver damage in chimeric mice fed CTRL diet, but receiving the microbiot

107 and lymphoid organs of CD11c-DTR bone marrow chimeric mice for up to 24 h postinfection.

108 Under competing conditions in bone marrow chimeric mice, FoxO1 deficiency did not perturb clonal e

109 e viral inoculation completely protected all chimeric mice from infection with serum-derived HCV of d

110 Experiments in bone marrow chimeric mice further demonstrated that myeloid cells ar

111 d macrophage trafficking was prevented in BM-chimeric mice generated with CCR2(KO) or CX3CR1(KO) dono

112 Here, we show that chimeric mice generated with Gata3-deficient fetal liver

113 Chimeric mice generated with Gata3-deficient fetal liver

114 Moreover, in chimeric mice generated with RanBPM(-/-) embryonic stem

115 We found that BTNL2(-/-) chimeric mice had a significant decrease in survival com

116 Chimeric mice had an increased proportion of CCR5(-/-) T

117 marrow from wild-type to Bmi1(-/-) mice, the chimeric mice had intermediate levels of pancreatic hypo

118 In the preliminary in vivo study in chimeric mice harboring the lamivudine/entecavir triple

119 Experiments based on bone marrow chimeric mice, however, demonstrated that inflammation i

120 o accumulated in the peritoneal cavity of UV-chimeric mice (ie, mice transplanted with BM from UV-irr

121 1-deficient compartment from the bone marrow chimeric mice (IL-21R knockout/wild-type).

122 or growth was also greatly accelerated in wt chimeric mice implanted with P2X7R-deficient bone marrow

123 er injury, and rapidly generated human liver chimeric mice in a reproducible and scalable fashion.

124 The use of chimeric mice in preclinical toxicology studies could im

125 tes not derived from iPS cells, we generated chimeric mice in which all hepatocytes were iPS cell der

126 These conditions allowed us to produce chimeric mice in which all mature B cells were derived e

127 ient (WASp(-/-)) mice without overt disease, chimeric mice in which only the B cell lineage lacks WAS

128 Bone marrow chimeric mice in which the entire hematopoietic compartm

129 ells was assessed in vitro and in vivo using chimeric mice in which the hematopoietic compartment inc

130 the ischemic brain, we used bone marrow (BM) chimeric mice in which the middle cerebral artery was oc

131 In these chimeric mice, in vivo administration of IL-33 or -25 fa

132 In chimeric mice, in which B cells were present but could n

133 We generated BM chimeric mice, in which non-BM derived cells were MHC cl

134 In both Abp1(-/-) and bone marrow chimeric mice, in which only B cells lack Abp1 expressio

135 ined for more than 3 months in the livers of chimeric mice, in which they underwent further maturatio

136 during regeneration because the recovery of chimeric mice, incapable of expressing p57 in HSPCs, phe

137 Liver fibrosis in chimeric mice indicated that NOX1 mediates the profibrog

138 imal tubule epithelial cells, and studies in chimeric mice indicated that the effects of TRPM2 are du

139 ale cells were detected in 50%-90% of female chimeric mice infected with H pylori strains; the presen

140 s, was able to suppress viral replication in chimeric mice infected with HCV GT1a by up to 2.5 log10

141 nfected humanized livers compared to control chimeric mice, irrespective of the human hepatocyte dono

142 Using bone marrow chimeric mice lacking ARHGAP25 in the hematopoietic comp

143 Mixed chimeric mice lacking B cell-derived granulocyte macroph

144 Chimeric mice lacking CD73 in tissue had larger cerebral

145 Chimeric mice lacking Cdk5 gene expression in hematopoie

146 creased endotoxin resistance, IFNAR(-/-) and chimeric mice lacking IFNAR in hematopoietic cells displ

147 Mixed bone marrow chimeric mice lacking IL-10 in dendritic cells showed mo

148 Chimeric mice lacking immune cell-specific CCR2 expressi

149 f retinopathy and allodynia were measured in chimeric mice lacking inducible nitric oxide synthase (i

150 To explore this, we utilized chimeric mice lacking Plxnb2 or Plxnd1.

151 rial burden and pulmonary immunopathology of chimeric mice lacking TLR2 in the hematopoietic compartm

152 Bone marrow chimeric mice lacking vimentin have reduced IL-1beta lev

153 o studies with mixed bone marrow irradiation chimeric mice, lacking B7-1/2 only on B cells, demonstra

154 -structural changes observed in FIAU-treated chimeric mice mirrored those of FIAU-treated human parti

155 In human-synovium chimeric mice, MRE11A(low) T cells were tissue-invasive

156 Nur77(-/-) chimeric mice on a Ldlr(-/-) background showed a 3-fold

157 ed moderately greater renal dysfunction than chimeric mice positive for IL-10 in dendritic cells.

158 In contrast, CD4-deficient chimeric mice possessing decay accelerating factor defic

159 ght-driven flexibility of period observed in chimeric mice provides a new perspective on the concept

160 istent virus replication in the lungs of the chimeric mice, providing evidence that p50 is required f

161 Gnaq(-/-) chimeric mice rapidly develop arthritis as well as other

162 In addition, miR-155(-/-) bone marrow chimeric mice receiving allo-HCT and miR-155(-/-) DCs sh

163 terns of IL-7Ralpha expression on T cells in chimeric mice reconstituted with Adora2a(+/+) and Adora2

164 ferentially accumulated in mixed bone marrow chimeric mice reconstituted with allotypically marked NO

165 Second, transplantable tumors developing in chimeric mice reconstituted with bone marrow cells from

166 r BTNL2 during malaria infection, we studied chimeric mice reconstituted with BTNL2(-/-) or wild-type

167 This phenotype was also observed in chimeric mice reconstituted with Clec1b(fl/fl)PF4-Cre bo

168 Irradiated fetal liver chimeric mice reconstituted with Gimap5-deficient cells

169 Moreover, chimeric mice reconstituted with NLRP3-deficient hematop

170 showed greater atheroprotective activity in chimeric mice reconstituted with TET2-deficient cells th

171 in bone marrow-depleted IL10KO mice (IL10KO chimeric mice) reduced transverse aortic constriction-in

172 The best available human liver chimeric mice rely on cellular transplantation into mice

173 In vivo the loss of SOCE in stim1(-/-) chimeric mice results in marked susceptibility to bacter

174 Experiments with bone marrow chimeric mice reveal a requirement for S1P in nonhematop

175 with dectin-1(-/-)/WT reciprocal bone marrow chimeric mice revealed a requirement for dectin-1 in bot

176 TLR4 bone marrow chimeric mice revealed an equal contribution of TLR4 on

177 Flow cytometric analysis of the chimeric mice revealed an increase in the number of dend

178 MDM2-TCR-engineered T cells into bone marrow chimeric mice revealed that Ag recognition in hematopoie

179 Analysis of fibrogenesis in CCR1- and CCR5-chimeric mice revealed that CCR1 mediates its profibroge

180 Testing bone marrow chimeric mice revealed that CD36 engagement on radioresi

181 Use of bone marrow chimeric mice revealed that CD39 expression on myeloid c

182 collate-induced peritonitis experiments with chimeric mice revealed that hematopoietic ppGalNAcT-1 is

183 Our study using bone marrow chimeric mice revealed that IFN-gamma production by brai

184 PECAM-1-KO and chimeric mice revealed that its metastasis-promoting eff

185 Mixed chimeric mice revealed that the defective maturation and

186 Bone marrow chimeric mice revealed that the Fo B cell-intrinsic loss

187 Studies of chimeric mice revealed that the hematopoietic Plexin C1

188 Analysis of bone marrow chimeric mice revealed that TLR and RLH signaling of rad

189 The use of bone marrow chimeric mice revealed the cellular sources of MMP-2 and

190 The use of bone marrow chimeric mice reveals that both an immune cell and a CNS

191 These human glial chimeric mice should permit us to define the specific co

192 udies of bleomycin-treated Mmp-8 bone marrow chimeric mice show that both leukocytes and lung parench

193 Bone marrow chimeric mice showed B cell intrinsic effect of ENPP1 se

194 In addition, bone marrow chimeric mice showed hematopoietic-derived factors were

195 Chimeric mice specifically lacking platelet VWF showed n

196 IGFBP-3-expressing plasmid into lasered GFP chimeric mice stimulated homing of EPCs, whereas reversi

197 fluorescent protein-positive (GFP(+)) adult chimeric mice subjected to laser-induced retinal vessel

198 type, Emc10-deficient, and Emc10 bone marrow-chimeric mice subjected to transient coronary artery lig

199 Further experiments in bone marrow chimeric mice suggested that the dual and opposing roles

200 Analysis of bone marrow chimeric mice suggested that the pathogenic effect of Fa

201 n wild-type and Blimp-1CKO-mixed bone marrow chimeric mice, suggesting an intrinsic role for Blimp-1

202 n left ventricular tissue sections of IL10KO chimeric mice suggests that myofibroblasts were derived

203 Here we demonstrate that human-liver chimeric mice support recovery of recombinant progeny fo

204 l pH-buffering capacity, allergen-challenged chimeric mice that contained Car4(-/-) hematopoietic cel

205 Chimeric mice that lack IL7Ralpha only on nonhematopoiet

206 Bone marrow chimeric mice that lack NOS2 in either nonhematopoietic

207 Chimeric mice that lacked p53 in leukocytes sustained in

208 Irradiated bone marrow chimeric mice that were either IL-6-deficient mice recon

209 by rose Bengal and laser photocoagulation on chimeric mice that were reconstituted with GFP+ bone mar

210 However, in p50(+/+)/p50(-/-) chimeric mice the p50(-/-) B cells exhibited a significa

211 We used bone marrow chimeric mice to confirm that the depletion of CD11c-exp

212 We vaccinated IL-1R1 bone marrow (BM) chimeric mice to determine whether IL-1R1 expression on

213 Here we used bone marrow chimeric mice to examine the effects of PD-L1 deficiency

214 ld-type and Irf4-deficient mixed bone marrow chimeric mice to investigate how and where IRF4 plays it

215 In this study, using bone marrow chimeric mice to restrict TLR4 signaling to either the S

216 four groups of bone marrow chimeric or sham chimeric mice to study the role of TLR4 on bone marrow o

217 Consistent with the result in chimeric mice, transfer of iNOS(+/+), but not iNOS(-/-),

218 Strikingly, chimeric mice transplanted with Mekk3(Deltaflox/-) BM ex

219 cZ(+) and desmin(+) pericytes confirmed that chimeric mice transplanted with Mekk3(Deltaflox/-) BM we

220 ose-dependent liver toxicity was detected in chimeric mice treated with FIAU 100, 25, or 2.5 mg/kg/d

221 s, gammadeltaT17 cells emerge in bone marrow chimeric mice upon induction of skin inflammation by top

222 LDLR in familial hypercholesterolaemia liver chimeric mice using an adeno-associated virus 9-based ge

223 en DCs were differentiated from the BM of UV-chimeric mice using FLT3 ligand or GM-CSF + IL-4, the ce

224 ur approach was to establish humanized glial chimeric mice using glial progenitor cells (GPCs) produc

225 Moreover, generating chimeric mice via UPRT(+) bone marrow transplants identi

226 When the dorsal skin of UV-chimeric mice was challenged with innate inflammatory ag

227 Furthermore, using bone marrow chimeric mice we demonstrate that LTi cells are the key

228 However, using chimeric mice we demonstrated that SHIP-1 expression is

229 grin and metalloprotease (ADAM)-17 radiation chimeric mice, we demonstrate for the first time that du

230 Using bone marrow chimeric mice, we demonstrate that an optimal response t

231 Using mixed bone marrow chimeric mice, we demonstrate that Nfil3 is critical for

232 Using gfp(+) bone marrow-transplant chimeric mice, we demonstrate that the MCP-1-recruited f

233 Using mixed bone marrow chimeric mice, we demonstrate that type I IFN sensitivit

234 reen fluorescent protein (GFP)(+/+) cells in chimeric mice, we demonstrated that Cdh5(-/-)GFP(+/+) HS

235 Using chimeric mice, we dissect the early (innate) and late (c

236 Using chimeric mice, we found a critical role for GAS6 in epit

237 Using bone marrow chimeric mice, we found that both ILC-intrinsic and ILC-

238 ld-type (WT), TLR4-knockout, and bone marrow chimeric mice, we found that endotoxin is readily filter

239 Using bone marrow-transferred chimeric mice, we found that LMP7 in both bone marrow- a

240 Using mixed bone marrow chimeric mice, we identified a requirement for MyD88 in

241 Using chimeric mice, we show that DC-derived IL-2 is required

242 Finally, using mixed bone marrow chimeric mice, we show that IFN-gamma-dependent infectio

243 Using mixed bone marrow chimeric mice, we show that the impact of NKG2D deficien

244 We show that the chimeric mice were able to control acute virus replicati

245 accumulation and alveolar barrier function, chimeric mice were compared.

246 In the present study, chimeric mice were created through bone marrow transplan

247 To determine the bone marrow origin, chimeric mice were created with enhanced green fluoresce

248 ow-derived progenitor cells, GFP-bone marrow chimeric mice were created.

249 d in vivo from the BM of UV-irradiated mice, chimeric mice were established.

250 Bone marrow-transplanted TLR2 chimeric mice were generated after the recipient mice we

251 Bone marrow chimeric mice were generated and subjected to cecal liga

252 In addition, chimeric mice were generated by bone marrow transplant t

253 Chimeric mice were generated by bone marrow transplantat

254 Chimeric mice were generated by injecting human haematop

255 The p47phox KO chimeric mice were generated by the combination of lipos

256 Reciprocal bone marrow chimeric mice were generated to compare hematopoietic an

257 Green fluorescent protein (GFP)-chimeric mice were generated to distinguish resident (re

258 Human liver chimeric mice were infected with a mixture of wild-type

259 The diminished responses in UV-chimeric mice were not due to different numerical or pro

260 b-diphtheria toxin (DT) receptor bone marrow-chimeric mice were selectively depleted following treatm

261 These chimeric mice were then fed the Western-type diet (WD) f

262 ext, LysM-GFP(+) and GFP(+) bone marrow (BM)-chimeric mice were used to determine the neuroanatomical

263 es in CCR6-deficient mice and in bone marrow chimeric mice where CCR6 deficiency was limited to the B

264 fer to HLA-B( *)27:05(+) mice or bone marrow chimeric mice where HLA-B( *)27:05 was restricted to eit

265 oads were also observed in mixed bone marrow chimeric mice, where B cell-extrinsic effects of miR-155

266 nctional importance of Lp-PLA2, we generated chimeric mice whose bone marrow-derived leukocytes were

267 tapasin-deficient mice, because bone marrow chimeric mice (wild-type recipients reconstituted with t

268 zed chimeric CD11c-DTR mice and is absent in chimeric mice with 50% normal bone marrow.

269 on with anti-CD4 antibodies or generation of chimeric mice with B cells deficient in both WASp and My

270 C57BL/6J female chimeric mice with BMDCs from male donors that express g

271 Here we utilize chimeric mice with competent hematopoietic-driven immuni

272 etastasis in mice via BMDC recruitment using chimeric mice with deficiency in CXCR4 and VEGFR1-tyrosi

273 fertility due to haploinsufficiency noted in chimeric mice with deletion of Tssk1 and 2 (companion pa

274 Inoculation of resulting simian liver chimeric mice with either HCV genotype 1a or 2a resulted

275 DLr(-/-) and LDLr(-/-)TLR2(-/-) mice created chimeric mice with green fluorescent protein (GFP) expre

276 Using chimeric mice with green fluorescent protein-expressing

277 Chimeric mice with Grp78 deletion only in the hematopoie

278 hly efficient in both HBV-infected and naive chimeric mice with HDV titers rising up to 1 x 10E9 copi

279 In contrast, p65KO athymic chimeric mice with human GBM, failed to inhibit tumor gr

280 ore represent a major obstacle to generating chimeric mice with human xenografts that are useful tool

281 Bone marrow chimeric mice with IFN-gamma-unresponsive lung epithelia

282 an equivalent level of hepatic steatosis in chimeric mice with jnk1(-/-) hematopoietic cells as comp

283 WT chimeric mice with MKK-6- and MKK-3-deficient bone marro

284 We made bone marrow chimeric mice with MMP-9 null and wild-type as donor and

285 infarct sizes and fibrin(ogen) deposition in chimeric mice with only platelet VWF were significantly

286 Chimeric mice with P2y2 deficiency restricted to hematop

287 Upon BDL, chimeric mice with p47phox KO BM-derived cells, includin

288 intersectional genetics to create temporally chimeric mice with SCN containing dopamine 1a receptor (

289 inferior vena cava, APP-KO mice, as well as chimeric mice with selective deficiency of APP in blood

290 henotype was reproduced by mixed bone marrow chimeric mice with Sema4C deficient only in B cells, ind

291 Furthermore, WT chimeric mice with transplanted p38gamma/delta(-/-) bone

292 Chimeric mice with USP21-deficient hematopoietic cells d

293 Chimeric mice with VWF present only in platelets were no

294 Chimeric mice with wild-type CNS cells and Ccr2(-/-) hem

295 k1(-/-) hematopoietic cells as compared with chimeric mice with wild-type or jnk2(-/-) hematopoietic

296 oximately 25% reduction of fibrosis, whereas chimeric mice with WT BM-derived cells and p47phox KO en

297 gnificantly increased in p38gamma/delta(-/-) chimeric mice with WT bone marrow compared with p38gamma

298 ted wild-type and WASP-deficient bone marrow chimeric mice, with full restoration of the MZ.

299 neration of genetically defined multiallelic chimeric mice without further strain intercrossing.

300 WKYMVm-induced leukocyte recruitment in chimeric mice (WT bone marrow to Fer(DR/DR) recipients o