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   1 discrete locations across the neocortex in a chimpanzee.                                             
     2 lecular state of CD33 resembling that of the chimpanzee.                                             
     3 fficiently replicates only in humans and the chimpanzee.                                             
     4 hat close social bonds also enhance trust in chimpanzees.                                            
     5 with subsequent spread into Nigeria-Cameroon chimpanzees.                                            
     6 increased in humans since they diverged from chimpanzees.                                            
     7 baboons that differ from those of humans and chimpanzees.                                            
     8 presence using grooming interactions of wild chimpanzees.                                            
     9  in polymorphisms shared by Neanderthals and chimpanzees.                                            
    10 erences in personality traits of bonobos and chimpanzees.                                            
    11 aviour facilitating cooperative behaviour in chimpanzees.                                            
    12 as well as the caudate nucleus in humans and chimpanzees.                                            
    13 relates in the production of these sounds in chimpanzees.                                            
    14 uring human evolution, but was maintained in chimpanzees.                                            
    15 cilitates prosocial behavior in children and chimpanzees.                                            
    16 ucture of referential food grunts in captive chimpanzees.                                            
    17 er additional examples of active teaching by chimpanzees.                                            
    18 ences for its ortholog, Patr-B, in 125 Gombe chimpanzees.                                            
    19             HIV-1 can infect only humans and chimpanzees.                                            
    20 t range and robustly infects only humans and chimpanzees.                                            
    21 most well-established cultural traditions in chimpanzees.                                            
    22 dominance rank and reproductive success than chimpanzees.                                            
    23  during natural intergroup conflicts in wild chimpanzees.                                            
    24 g characteristics of social learning in wild chimpanzees.                                            
    25 epresent a group-level cultural tradition in chimpanzees.                                            
  
    27 variation in the FOXP2 coding sequence in 63 chimpanzees, 11 bonobos, 48 gorillas, 37 orangutans and 
    28 oming-handclasp style preferences in captive chimpanzees [2], we tested the alternative view posed by
  
    30 has previously been reported for tool use in chimpanzees [3] and in the vocal and feeding behavior of
  
    32 ersistently infected patients and vaccinated chimpanzees, a phenomenon of so-called antibody interfer
    33 rtefacts at particular locations observed in chimpanzee accumulative stone throwing may have implicat
    34  study, we administered a single dose of the chimpanzee adenovirus 3 (ChAd3) vaccine encoding the sur
    35 ed, placebo-controlled, phase 3 trial of the chimpanzee adenovirus 3 vaccine (ChAd3-EBO-Z) and the re
    36 linical development of replication-defective chimpanzee adenovirus 3 vector vaccine expressing Zaire 
    37    PfUIS3 was expressed in the viral vectors chimpanzee adenovirus 63 (ChAd63) and modified vaccinia 
    38 a-naive adults were vaccinated with either a chimpanzee adenovirus 63 and modified vaccinia virus Ank
  
  
    41 munogenicity of the monovalent, recombinant, chimpanzee adenovirus type-3 vector-based Ebola Zaire va
    42    Here, we utilized a replication-deficient chimpanzee adenovirus vaccine platform with an establish
  
  
    45 novirus C) vectors are more immunogenic than chimpanzee adenovirus vectors from species Human adenovi
    46 ies that include Human adenovirus-5 (AdHu5), Chimpanzee adenovirus-6 (AdC6) or -7 (AdC7), Vaccinia vi
  
    48 evelopment of vaccine vectors from human and chimpanzee adenoviruses, far less is known about rhesus 
  
    50 rged long before the separation of human and chimpanzee ancestors and then subsequently and specifica
    51 t comprehensive map of MEIs to date spanning chimpanzees, ancient hominids, and modern humans and rev
  
    53 stent with co-divergence with their gorilla, chimpanzee and bonobo hosts, suggesting a timescale for 
    54 uivalent activity to human A3C I188 and that chimpanzee and gorilla A3C form dimers at the same inter
  
  
    57 t elephant, forest buffalo, western gorilla, chimpanzee and mandrill) in 225 sites throughout the reg
    58  investigate its divergence from orthologous chimpanzee and modern human sequences and find strong su
    59  NFAT (nuclear factor of activated T cells); chimpanzee and orangutan BILF1 molecules were unable to 
    60  receptors were internalized, BILF1 from the chimpanzee and orangutan displayed an altered cellular l
  
    62 lymphoblastoid cell lines (LCLs) from human, chimpanzee and rhesus, and we identify patterns of m(6)A
    63 Project, we also used it to discover MEIs in chimpanzees and ancient (Neanderthal and Denisovan) homi
    64 n apes, rates are approximately 2% higher in chimpanzees and approximately 7% higher in the gorilla t
  
  
  
    68 ese findings demonstrate experimentally that chimpanzees and bonobos can take into account what other
  
  
    71 ject matches, both children and Pan species (chimpanzees and bonobos) spontaneously used relational s
    72 hysical activity, human TEE exceeded that of chimpanzees and bonobos, gorillas and orangutans by appr
  
  
  
    76 e ratios of substitution rates in humans and chimpanzees and differences in rates of autosomal substi
    77 was previously shown by our group to protect chimpanzees and generate broad cross-neutralizing antibo
    78 aria parasites, though widespread among wild chimpanzees and gorillas, have not been detected in bono
  
  
  
    82 substitution elasticities is similar between chimpanzees and humans but the shape is quite different,
    83 s of brain size and cortical organization in chimpanzees and humans by studying phenotypic similariti
    84   Therefore, DP(84Gly), found only in common chimpanzees and humans, uniquely uses both class I and I
  
  
  
    88 avel thus appears to foster tool use in wild chimpanzees and may also have been a driving force in ea
    89 b elongation), convergent adaptation between chimpanzees and orangutans (digital elongation) and comp
    90 wo variable polyglutamine microsatellites in chimpanzees and orangutans and found three nonsynonymous
    91 he likely size of the ancestor of humans and chimpanzees and the evolutionary history of selection on
    92 idual differences in the use of AG sounds by chimpanzees and, here, we examined whether changes in co
    93  compared with our closest living relatives (chimpanzees) and early fossil hominins, in having an enl
  
  
  
    97 ER (human, bovine, and mouse) and AR (human, chimpanzee, and rat) were used to assess the sensitivity
    98 re, applying the same methodology to humans, chimpanzees, and capuchins, we provide evidence that all
  
  
   101 ensity for reactive aggression compared with chimpanzees, and in this respect humans are more bonobo-
   102 ne models following vaccination with human-, chimpanzee-, and simian-derived rAds encoding SIV-Gag an
  
   104  to many human self-reported findings, older chimpanzees are less likely to console than are younger 
  
   106 oposed, however, that in contrast to humans, chimpanzees are only able to do this in competitive inte
  
  
  
   110 ese findings demonstrate experimentally that chimpanzees are willing to incur a material cost to deli
  
   112 os harbour P. gaboni, formerly only found in chimpanzees, as well as a potential new species, Plasmod
   113 fferences explain this contrast by comparing chimpanzees at Kalinzu (Uganda) and bonobos at Wamba (DR
   114  confirmed that they were found in human and chimpanzee BAC and FOSMID clones sequenced as part of th
   115 os into the ancestors of central and eastern chimpanzees between 200,000 and 550,000 years ago, proba
   116 nformation and debates on whether the common chimpanzee-bonobo divergence is linked to heterochrony. 
  
   118 two functional amino acid substitutions from chimpanzees, bonobos and gorillas, with an additional fi
   119  the gut arose via cospeciation with humans, chimpanzees, bonobos, and gorillas over the past 15 mill
   120 y expenditure (TEE; kcal day(-1)) in humans, chimpanzees, bonobos, gorillas and orangutans to test th
  
  
  
  
  
   126 behavior of our closest animal relative, the chimpanzee, but long-term field studies have since revea
   127 ehavior was strikingly similar to reports in chimpanzees, but was never observed in gorillas until af
   128 in size and cortical organization is high in chimpanzees, cerebral cortical anatomy is substantially 
   129  studies, particularly those in which direct chimpanzee-child comparisons have been made, delineate a
   130 es there were only four minor changes in the chimpanzee clade, and all were reversions to the ancestr
   131 n than autosomal ones (compared to the human/Chimpanzee common ancestor) if highly expressed, but not
  
   133  have been traced to geographically distinct chimpanzee communities in southern Cameroon, the reservo
   134 rial-viral co-infections in wild and captive chimpanzee communities in the course of several respirat
  
  
   137 , we use epigenomic profiling from human and chimpanzee cranial neural crest cells to systematically 
  
   139 e diversity, and regional variation in human-chimpanzee divergence is only partly explained by hetero
   140 ing this approach, we estimate the human and chimpanzee divergence time is 12.1 million years, and th
   141 nome have influenced fitness since the human-chimpanzee divergence, and they suggest that recent evol
   142 perior mass-specific muscular performance of chimpanzees does not stem from differences in isometric 
   143 eak dorsiflexion angles at all MTPJs than do chimpanzees during bipedal and quadrupedal walking, with
   144 utic vaccination in two chronically infected chimpanzees during treatment with a direct-acting antivi
   145  These results suggest that, like humans and chimpanzees, early hominins walked with upper body rotat
  
  
  
  
   150 monocyte-derived macrophages from humans and chimpanzees exhibited marginal differences in LPS respon
   151 ecord of repeated observations of individual chimpanzees exhibiting stone tool use for a purpose othe
  
  
   154 ditional males to yield a total sample of 19 chimpanzees, four bonobos, 14 gorillas, and six oranguta
  
   156 ent in more than 3,000 loci across human and chimpanzee genomes and has a promoter and a conserved st
  
   158 on profiles in sperm of seven species-human, chimpanzee, gorilla, rhesus macaque, mouse, rat, and dog
   159 es has taught us about the cultural lives of chimpanzees, gorillas, and orangutans and consider the w
   160 KSHV), and closely related rhadinoviruses of chimpanzees, gorillas, macaques and other Old World prim
  
  
   163 solation tendencies over 10 years across two chimpanzee groups and show evidence of consistent 'empat
   164  found four populations in West Africa where chimpanzees habitually bang and throw rocks against tree
   165  CenB The last common ancestor of humans and chimpanzees had diverse lineage III KIR that passed on t
   166 emonstrate dramatic differences in human and chimpanzee HARE5 activity, with human HARE5 driving earl
  
  
  
  
  
   172 dies of hepatitis B virus (HBV) infection in chimpanzees have indicated that cytokines released by T 
  
  
   175 all detected tandem repeats and confirm that chimpanzee herpesvirus 1 (ChHV-1) is a separate species 
   176 the last common ancestor (LCA) of humans and chimpanzees, hominids (great apes and humans), or homino
  
   178 le case of evolutionary stasis for since the chimpanzee-human split c.8 Ma among >120 head-neck (HN) 
  
  
  
   182 n cases of acute HCV infection in humans and chimpanzees, including three examples of virus transmiss
   183 e generated a panel of 7 fully characterized chimpanzee induced pluripotent stem cell (iPSC) lines de
  
  
   186 sequencing and DNA methylation data from the chimpanzee iPSCs and the corresponding fibroblast lines,
  
  
   189 oots shared by our last common ancestor with chimpanzees, likely expediting fitness gains during inte
   190 Data are consistent with the hypothesis that chimpanzee lip-smacks function to coordinate and prolong
  
  
  
   194 tical review of available data suggests that chimpanzee mass-specific muscular performance is a more 
   195 Recent studies purported to demonstrate that chimpanzees, monkeys and corvids possess a basic Theory 
  
  
   198  on coordination behaviour in three pairs of chimpanzees (mother/offspring dyads) during an experimen
  
   200 ist among chimpanzee subspecies: The western chimpanzee MSY phylogeny has a TMRCA of only 13.2 (10.8-
  
  
   203 e and power output is 1.35 times higher in a chimpanzee muscle than a human muscle of similar size.  
   204 f group-hunting predators such as wolves and chimpanzees (n = 1,382 cases), hostile takeovers in indu
  
   206 study, we analysed the communication of wild chimpanzees of Budongo Forest, Uganda, as they entered a
  
  
   209 mous single nucleotide polymorphisms, one in chimpanzees, one in gorillas and one in orangutans with 
   210 the CS, a finding previously undocumented in chimpanzees or any nonhuman primate.SIGNIFICANCE STATEME
  
   212 BILF1 receptors from EBV and LCVs from NHPs (chimpanzee, orangutan, marmoset, and siamang) were selec
   213 g, humIle418Ala) and 15-lipoxygenating (man, chimpanzee, orangutan, rabbit, ratLeu353Phe) ALOX15 vari
   214 nk flexibility present in humans, but not in chimpanzees, other great apes, or australopithecines.   
  
   216 x call in great ape vocal communication, the chimpanzee (Pan troglodytes schweinfurthii) 'pant hoot'.
  
   218 man animal tool use comes from three Western chimpanzee (Pan troglodytes verus) sites in Cote d'Ivoir
   219 operation, whereas our closest relative, the chimpanzee (Pan troglodytes), is often characterized as 
   220  long-term rank trajectories in wild eastern chimpanzees (Pan troglodytes schweinfurthii) and find re
   221 ngth between two neighbouring communities of chimpanzees (Pan troglodytes schweinfurthii) in the Kali
   222 ect of offspring quality (body size) in wild chimpanzees (Pan troglodytes schweinfurthii), a species 
  
  
  
   226  the 1920s, it has been reported that common chimpanzees (Pan troglodytes) differ from humans in bein
  
   228 ate.SIGNIFICANCE STATEMENT Recent studies in chimpanzees (Pan troglodytes) have shown that some can l
   229 atives of humans, bonobos (Pan paniscus) and chimpanzees (Pan troglodytes), share many traits that ar
   230 present in nonhuman primate species, such as chimpanzees (Pan troglodytes), to a limited degree.     
   231 ons on over 3000 conflict interactions in 44 chimpanzees (Pan troglodytes), we provide evidence for r
   232 clude that the complex acoustic structure of chimpanzee pant hoots is linked to a range of socially r
   233 ification strategy to sequence the genome of chimpanzee parasites classified as Plasmodium reichenowi
  
  
  
   237 ago, after the common ancestor of humans and chimpanzees, perhaps contributing to speciation of the g
   238 dation datasets encompassing human, macaque, chimpanzee, pig, mouse, rat and all seven Baltimore viru
  
  
   241 tive view posed by Wrangham et al.[1] in the chimpanzee populations that our original results were ba
  
  
   244 arisons of modern human brains with those of chimpanzees provide an additional line of evidence to de
  
  
  
  
  
   250 n addition to data from 17 mid- to long-term chimpanzee research sites, we sampled a further 34 Pan t
   251 ncing of a P. malariae relative that infects chimpanzees reveals similar signatures of selection in t
   252 is report contributes novel behaviour to the chimpanzee's ethogram, and highlights how crucial inform
  
  
  
   256   Despite being closely related, bonobos and chimpanzees show remarkable behavioral differences, the 
   257  active against SERINC5 than HIV-2 Nefs, and chimpanzee SIV (SIVcpz) Nefs are more potent than those 
  
  
  
   261 crease in body mass in early hominins from a chimpanzee-sized LCA.The pattern of body size evolution 
  
  
   264 nce, in particular suggesting that the human-chimpanzee split may have occurred as recently as 6.6 My
   265   Additionally, combining data from the main chimpanzee study communities across Africa supported thi
  
   267  substantially less diversity than Patr-B in chimpanzee subspecies and HLA-B in indigenous human popu
   268  particularly marked differences exist among chimpanzee subspecies: The western chimpanzee MSY phylog
   269 l morphology intermediate between humans and chimpanzees, suggesting that this species used different
   270  more frequent and intense in male-dominated chimpanzees than in bonobos, where the highest-ranking i
  
  
  
   274 ssess whether the cerebral cortex of captive chimpanzees that learned to voluntarily produce sounds t
  
   276 perior, portion was significantly greater in chimpanzees that reliably produced AG sounds compared wi
   277 riatal dopaminergic input was not altered in chimpanzees that used socially learned attention-getting
   278 owing the integration of two groups of adult chimpanzees, the acoustic structure of referential food 
  
  
   281 rrow host range of HCV and restricted use of chimpanzees, there is currently no suitable animal model
  
   283 cytidine deaminase APOBEC3G as a barrier for chimpanzee-to-gorilla, but not gorilla-to-human, virus t
  
   285  rates of increase for six orally vaccinated chimpanzees very similar to four intramuscularly vaccina
   286  to show that, contrary to current thinking, chimpanzees walking bipedally rotate their lumbar and th
   287  the Functionally Referential Food Grunts of Chimpanzees", Watson et al.[1] claimed that they "provid
   288 LV-1-positive hunters bitten by a gorilla or chimpanzee were infected with a subtype B strain similar
   289 o conditions, zoo-housed apes (2 gorillas, 5 chimpanzees) were familiarized to videos of a human hand
   290  rates of gestural communication in pairs of chimpanzees when the intended recipient was within 10 m 
   291 atitis C virus (HCV) only infects humans and chimpanzees, while GB virus B (GBV-B), another hepatotro
  
  
  
  
   296 od became substantially less efficient, nine chimpanzees with socially-acquired information (four of 
  
   298 assess urinary glucocorticoids (uGC) in wild chimpanzees, with or without their bond partners, after 
  
  
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