ライフサイエンスコーパス: chiral ligand

1 nd could be minimized through the use of the chiral ligand.

2 way to overcome the deactivating effect of a chiral ligand.

3 us placement of fluorine substituents in the chiral ligand.

4 cols without the use of (-)-sparteine as the chiral ligand.

5 e of a commercially available Ni complex and chiral ligand.

6 with (S)-SEGPHOS, the same enantiomer of the chiral ligand.

7 lectivities are achieved using TangPHOS as a chiral ligand.

8 en demonstrated for a Sm(III) complex with a chiral ligand.

9 t can be formed by appropriate choice of the chiral ligand.

10 uses commercially available cobalt salts and chiral ligands.

11 xplore starting points for the design of new chiral ligands.

12 ly with the most acidic member of a suite of chiral ligands.

13 nly recently emerged as a versatile class of chiral ligands.

14 Cu(II) ions with ditopic bisoxazoline-based chiral ligands.

15 supply issues relating to these widely used chiral ligands.

16 cally active compounds, natural products and chiral ligands.

17 stituted pi-allyl complexes with DPPBA-based chiral ligands.

18 s of Lewis acidic metal salts coordinated to chiral ligands.

19 91 to 94% ee for a range of substrates when chiral ligand 14 is employed.

20 The trimeric complex ion (three chiral ligands-2 mol of the analyte and 1 mol of the ref

21 (CDR) of rac-2-lithio-N-Boc-piperidine using chiral ligand 8 or its diastereomer 9 in the presence of

22 nd order in TMEDA and 0.5 and 0.265 order in chiral ligands 8 and 10, respectively.

23 The chiral ligands allow the full control of stereochemistry

24 lides [Cu(II) or Ag(I)] with the appropriate chiral ligand and C60 is described.

25 ric repulsions between the t-Bu group of the chiral ligand and the alpha-methylene hydrogens of the e

26 Match/mismatch effects between the chiral ligand and the chiral TADDOL-phosphate counterion

27 (1) has potential utility as a scaffold for chiral ligands and as a modified backbone unit for pepti

28 ls represent potentially useful synthons for chiral ligands and auxiliaries.

29 ciated with the use of enantiomerically pure chiral ligands and catalysts.

30 mol % of easily accessible amino acid-based chiral ligands and commercially available AgOAc.

31 information on the plethora of sulfur-based chiral ligands and organocatalysts used in asymmetric sy

32 e new building blocks for the synthesis of P-chiral ligands and organocatalysts.

33 structural features of the amino acid-based chiral ligands and the chiral ligand's effectiveness in

34 of commercially available metal catalyst and chiral ligand, and gives the highest yields and selectiv

35 These chiral ligands are easy to prepare and flexible for modi

36 e of chiral induction was also observed when chiral ligands are electronically tuned in the same mann

37 Two easily accessible chiral ligands are identified as optimal for reactions o

38 iral organocatalysts or metal complexes with chiral ligands are used, has become the most valuable me

39 he AA2 moiety of the peptidic segment of the chiral ligand associates and delivers HNC to the activat

40 d cascades that exploit a simple, recyclable chiral ligand can convert symmetrical ketoesters to comp

41 Catalytic alkylations with Et2Zn require a chiral ligand carrying two amino acid moieties (valine a

42 inc to aromatic nitroalkenes by known copper-chiral ligand catalysts.

43 lts were compared with those of two existing chiral ligands, Chiraphite and BINAPHOS, whose utility i

44 resolved diastereomeric 2-lithiopyrrolidine-chiral ligand complexes provided the enantiomerically en

45 rate that lower alkene amounts and/or higher chiral ligand concentration can minimize the deleterious

46 st effectively promoted in the presence of a chiral ligand containing a single amino acid (benzyl cys

47 pargyl acetates and propargyl acetals in the chiral ligand-controlled Rautenstrauch reaction.

48 en developed recently, and this new class of chiral ligands could enable their modification for asymm

49 The complex of palladium(0) and the chiral ligand derived from the diamide of trans-1,2-diam

50 smox]12(OH2)3}.212H2O (1), where hismox is a chiral ligand derived from the natural amino acid l-hist

51 tituted biaryls that can be useful in future chiral ligand designs.

52 tereoselective dihydroxylation employing the chiral ligand (DHQ)2PHAL was used as the key step to int

53 ccurs with racemic cyclic electrophiles, the chiral ligand employed reacts kinetically faster with th

54 The combination of chiral ligand exchange on Cu(II) complexes in aqueous ba

55 L-His was used as a chiral ligand-exchange selector and copper (II) as a cen

56 tion of an open tubular capillary column for chiral ligand-exchange separation and determination of m

57 The newly designed chiral ligand exhibits high diastereoselective control d

58 Phos, had previously only been employed as a chiral ligand for transition metals, not as an efficient

59 y functional theory (DFT) based screening of chiral ligands for transition-metal-catalyzed reactions

60 system comprising CuBr.SMe2 and TaniaPhos as chiral ligands gives rise to a range of branched product

61 ic 2-lithiopyrrolidines in the presence of a chiral ligand have been achieved.

62 ome proliferator activated receptors (PPARs) chiral ligands have been designed following the accepted

63 as well as enantioselective protocols using chiral ligands have been successfully developed during t

64 on transition metals coordinated to suitable chiral ligands, heterogeneous chiral catalysts could off

65 The method can determine if a chiral ligand imparts the observed selectivity by stabil

66 ing resin 12 has subsequently been used as a chiral ligand in the catalytic addition at 0 degrees C o

67 horamidite was identified to be an effective chiral ligand in the palladium-catalyzed reaction.

68 Furthermore, assessment of a number of chiral ligands in a challenging asymmetric Suzuki-Miyaur

69 of dihedral angles, which may be explored as chiral ligands in enantioselective catalysis if decorate

70 t2Zn and Me2Zn, promoted by amino acid-based chiral ligands in the presence of Al-based alkoxides, af

71 tereodiscriminating fragments for some known chiral ligands including the Masamune dimethylborolane,

72 practical as well as efficient, because the chiral ligand is both readily prepared from R,R- or S,S-

73 0.1-1 mol % catalyst (4 degrees C), and the chiral ligand is readily prepared from commercially avai

74 er via chiral resolution or by employment of chiral ligands is described, characterization techniques

75 or a range of delta-substituted dienals when chiral ligand L3 is employed.

76 Chiral ligand L4 was found to be optimal in the DAAA of

77 The easy recovery of the chiral ligand makes the application of these new catalys

78 catalysis is achieved for the first time via chiral ligand metal cooperation.

79 Using a modular amino acid based chiral ligand motif, a library of ligands was synthesize

80 e or dynamic resolution in the presence of a chiral ligand of N-Boc-2-lithiopiperidine followed by th

81 inetic resolution of secondary alcohols as a chiral ligand on palladium and as an exogenous chiral ba

82 We propose that well-organized chiral ligands on the surface of self-assembled nanostru

83 The trimeric complex ions (three chiral ligands--one of the analyte and two of the refere

84 Chiral ligands play a central role in enantioselective t

85 achiral counterion (equimolar to the neutral chiral ligand-proton complex present at low catalyst loa

86 from palladium(II) trifluoroacetate and the chiral ligand (S)-t-BuPyOx.

87 the amino acid-based chiral ligands and the chiral ligand's effectiveness in reactions involving ach

88 The chiral ligand (-)-sparteine and PdCl(2) catalyze the ena

89 tform for exploring the relationship between chiral ligand structure and enantioselective olefin oxid

90 al Lewis acids derived from relatively small chiral ligands, suggesting the pyrazolidinone templates

91 the presence 0.5-10 mol % of a Zr salt and a chiral ligand that contains two inexpensive amino acids

92 pensive metal salt (AgOAc) and an air stable chiral ligand that is prepared in three steps from comme

93 A new series of modular chiral ligands that are derived from amino acids were pr

94 With (S)-t-Bu-PyOX as the chiral ligand, this method delivers a variety of alpha-t

95 In the presence of appropriate chiral ligands, this reaction is rendered enantioselecti

96 zed enantioselective transformations rely on chiral ligands tightly bound to the metal to induce asym

97 atter compound has the potential to act as a chiral ligand to metal centers.

98 m each play a distinct role: one serves as a chiral ligand to provide stereoinduction in the addition

99 The development of chiral ligands to direct the course and stereoselectivit

100 of a large and chemically diverse set of 30 chiral ligands to effect asymmetric cyclization of 2-(N,

101 l counterion can be combined additively with chiral ligands to enable an asymmetric transformation th

102 The coordination of chiral ligands to Lewis acid metal derivatives, a useful

103 A simple norephedrine-based chiral ligand was synthesized that gives alkylation prod

104 high enantiomeric excess when an appropriate chiral ligand was used.

105 The conformational flexibility of the chiral ligands was found to be an important factor in th

106 actions catalyzed by complexes of nonracemic chiral ligands were also conducted, and the first enanti

107 Ruthenium complexes employing axially chiral ligands were found to be effective asymmetric hyd

108 A range of N-substituents and chiral ligands were investigated for the dynamic resolut

109 ic alcohols can be carried out in water with chiral ligands, which incorporate sulfonamide and hydrox

110 merically enriched starting material using a chiral ligand with the opposite configuration, enables c

111 We designed three closely related chiral ligands with different point chiralities, and obs