ライフサイエンスコーパス: chloride channel

1 phospholipid scramblase and Ca(2+)-activated chloride channel.

2 rpolarization-activated, inwardly rectifying chloride channel.

3 ing states through the MOD-1 serotonin-gated chloride channel.

4 feedback chemical synapse associated with a chloride channel.

5 lalpha gene, which encodes a glutamate-gated chloride channel.

6 rface stability, and/or function of the CFTR chloride channel.

7 ce expression of the alpha1 glycine receptor chloride channel.

8 s transmembrane conductance regulator (CFTR) chloride channel.

9 rupts both the processing and gating of this chloride channel.

10 ABA(A) receptor, a postsynaptic ligand-gated chloride channel.

11 elegans, the first identified tyramine-gated chloride channel.

12 m, of a peptide toxin inhibitor of the ClC-2 chloride channel.

13 constitutes the olfactory calcium-activated chloride channel.

14 ing it the highest affinity inhibitor of any chloride channel.

15 ed by loss-of-function mutations in the CFTR chloride channel.

16 g a phosphorylation-activated, but ATP-gated chloride channel.

17 tion of the ancillary function of EAAT1 as a chloride channel.

18 detect ANO4 activity as a calcium-activated chloride channel.

19 osis (CF) is caused by mutations in the CFTR chloride channel.

20 lar complex and function of Ca(2+)-activated chloride channels.

21 to other ion channels such as potassium and chloride channels.

22 ular chloride, indicating that ATP inhibited chloride channels.

23 that ATP acts on P2Y(1) receptors to inhibit chloride channels.

24 an accessory subunit of renal and inner ear chloride channels.

25 ide removal through the concurrently opened, chloride channels.

26 ttranslational modification of CLC-K/barttin chloride channels.

27 ate recognition arose in the glutamate-gated chloride channels.

28 A gene that is prominently affected encodes chloride channel 1 (Clcn1), resulting in hyperexcitabili

29 expression of the Cl channel kidney-specific chloride channel 1 and its subunit Barttin, the urea tra

30 ductions in pathological RNA foci, rescue of chloride channel 1 protein expression, and decreased myo

31 Immunostaining suggested lower expression of chloride channel 2 and cystic fibrosis transmembrane reg

32 In Mus spretus, the chloride channel 4 gene Clcn4-2 is X-linked and dosage c

33 mutations of the chloride/proton antiporter, chloride channel-5 (CLC-5), resulting in low-molecular-w

34 f the nervous system using a histamine-gated chloride channel abolishes pumping, and optogenetic stim

35 The 3-gene signature of periostin, chloride channel accessory 1 (CLCA1), and Serpin beta2 (

36 We report that expression of chloride channel accessory protein hCLCA2 is a character

37 tokinin antagonists, neurokinin-antagonists, chloride channel activators, guanylate cyclase C agonist

38 Sphingomyelinase C (SMase) inhibits CFTR chloride channel activity in multiple cell systems, an e

39 Here we show that hBest1 chloride channel activity is regulated by ceramide and p

40 Here we report light-induced chloride channel activity of a purified ACR protein reco

41 vage and a novel mechanism for regulation of chloride channel activity specific to the mucosal interf

42 Moreover, ANO1 chloride channel activity was important for cell viabili

43 uctance regulator (CFTR) that compromise its chloride channel activity.

44 ted anion efflux and exhibited robust single chloride channel activity.

45 ockdown or pharmacological inhibition of its chloride-channel activity reduced EGF receptor (EGFR) an

46 meric Caenorhabditis elegans glutamate-gated chloride channel alpha (GluCl), at 3.3 A resolution.

47 s transmembrane conductance regulator (CFTR) chloride channel, an ATP binding cassette (ABC) protein

48 orter superfamily, is a cyclic AMP-regulated chloride channel and a regulator of other ion channels a

49 in glutathione S-transferase, intracellular chloride channel and annexin molecules from various sour

50 resumed to assemble into a calcium-activated chloride channel and be involved in chloride transport b

51 Ivacaftor is a potentiator of the CFTR chloride channel and is in worldwide clinical use for th

52 ClC-1 is the dominant sarcolemmal chloride channel and plays an important role in regulati

53 he removal of Ca(2+) leads to closure of the chloride channel and response termination.

54 change in the receptor, opening an intrinsic chloride channel and thereby dampening neuronal excitabi

55 hogenicity of splice site mutations of CLC-1 chloride channels and a new gene association for Anderse

56 he ClC protein family includes voltage-gated chloride channels and chloride/proton exchangers.

57 rty observed in endogenous calcium-activated chloride channels and could be relevant to physiological

58 ure the activity and location of subcellular chloride channels and transporters in living cells in a

59 Most mammalian chloride channels and transporters in the CLC family dis

60 The CLC family of chloride channels and transporters is a functionally div

61 ClC chloride channels and transporters play major roles in c

62 ffect on a battery of other major classes of chloride channels and voltage-gated potassium channels.

63 interaction with claudin-4, the paracellular chloride channel, and delocalization of claudin-4 from t

64 nic anhydrase, a member of the ClC family of chloride channels, and a member of the Gpr1/Fun34/YaaH f

65 The calcium-activated chloride channel ANO1 regulates multiple physiological p

66 mutations in the proposed calcium-activated chloride channel ANO5/TMEM16E gene have been identified.

67 The calcium-activated chloride channel anoctamin 1 (ANO1) is located within th

68 Mutations in human CLC-1 chloride channel are associated with the skeletal muscle

69 s transmembrane conductance regulator (CFTR) chloride channel are predicted to slow cyst enlargement

70 ClC-K chloride channels are crucial for auditory transduction

71 CLC-K/barttin chloride channels are essential for NaCl re-absorption i

72 CLC-K chloride channels are expressed in the kidney and in the

73 CLC-K chloride channels are expressed in the kidney and the in

74 Nematode glutamate-gated chloride channels are targets of the macrocyclic lactone

75 Non-CFTR mechanisms, such as ClC-type chloride channels, are likely involved in maintaining el

76 F transmembrane conductance regulator (CFTR) chloride channel at the apical plasma membrane.

77 CFTR is a major prosecretory chloride channel at the ocular surface.

78 carb and metaflumizone), the glutamate-gated chloride channel (avermectins), the octopamine receptor

79 The glutamate-gated chloride channel AVR-14 is expressed in HOA.

80 , which encodes a putative calcium-activated chloride channel belonging to the Anoctamin family of pr

81 nsmembrane conductance regulator (CFTR) is a chloride channel belonging to the ATP-binding cassette t

82 In addition, applying a chloride channel blocker impeded TBSV replication in Nic

83 ast IPSPs were blocked by the GABAA receptor chloride channel blocker picrotoxin, whereas the slow su

84 thiocyanatostilbene-2,2'-disulfonic acid), a chloride channel blocker previously shown to prevent 1,2

85 A glutamate transporter-associated chloride channel blocker TBOA suppresses I(RC) but not I

86 1.5 nmol min(-1)), which was blocked by the chloride channel blockers niflumic acid (81%) and DIDS (

87 s transmembrane conductance regulator (CFTR) chloride channel, but the structural basis of blocker bi

88 The inhibition of chloride channels by extracellular ATP has implications

89 of small CFTR fragments, which do not act as chloride channels by themselves, rescue DeltaF508-CFTR.

90 cretion and activation of the Ca2+-activated chloride channel (CaCC) anoctamin 1 (ANO1, also known as

91 TMEM16A (ANO1) is a calcium-activated chloride channel (CaCC) expressed in secretory epithelia

92 function 16 (TMEM16A) is a calcium-activated chloride channel (CaCC) important for neuronal, exocrine

93 kinase A (PKA), whereas the Ca(2+)-activated chloride channel (CaCC) is activated by Ca(2+) agonists

94 identity of the olfactory calcium-activated chloride channel (CaCC) is unknown.

95 at the recently identified calcium-activated chloride channel (CaCC) TMEM16A is expressed in the adul

96 n evolutionarily conserved calcium-activated chloride channel (CaCC), regulates cytoplasmic Cl(-) hom

97 vage prevent activation of calcium-activated chloride channel (CaCC)-mediated chloride transport.

98 M16A (ANO1) functions as a calcium-activated chloride channel (CaCC).

99 s essential subunits of the Ca(2+)-activated chloride channel (CaCC).

100 Calcium-activated chloride channels (CaCC) with similar hallmark features

101 have been shown to express calcium activated chloride channels (CaCCs) and there is evidence for thei

102 Calcium-activated chloride channels (CaCCs) are key players in transepithe

103 Calcium-activated chloride channels (CaCCs) are major regulators of sensor

104 Calcium-activated chloride channels (CaCCs) encoded by TMEM16A control neu

105 Calcium-activated chloride channels (CaCCs) play important roles in severa

106 e physiologically relevant calcium-activated chloride channels (CaCCs) present in many tissues.

107 Ca2+ -activated chloride channels (CaCCs) regulate numerous physiologica

108 Ca(2+)-activated chloride channels (CaCCs) regulate numerous physiologica

109 Bestrophin calcium-activated chloride channels (CaCCs) regulate the flow of chloride

110 TMEM16A forms calcium-activated chloride channels (CaCCs) that regulate physiological pr

111 TMEM16A and TMEM16B are calcium-activated chloride channels (CaCCs) with important functions in ma

112 rents carried by TRPC2 and calcium-activated chloride channels (CACCs).

113 al signaling that involves calcium-activated chloride channels (CaCCs).

114 g of lung sections, Western blot analysis of chloride channel calcium activated 3 (CLCA3) expression

115 The chloride channel calcium-activated (CLCA) family are sec

116 Here, we define a signaling pathway from chloride channel calcium-activated 1 (CLCA1) to MAPK13 t

117 PAGE and mass spectrometry identified murine chloride channel calcium-activated 1 (mCLCA1) as the 10.

118 tation-related defect in the epithelial-cell chloride channel called CF transmembrane conductance reg

119 ective cation channels, and Ca(2+)-activated chloride channels can contribute to synchronization, whe

120 Mutations in the human bestrophin 1 (hBest1) chloride channel cause Best vitelliform macular dystroph

121 s transmembrane conductance regulator (CFTR) chloride channel caused by pathogenic mutations.

122 F transmembrane conductance regulator (CFTR) chloride channels causes defective secretion by submucos

123 ) in which loss-of-function mutations in the chloride channel CF transmembrane conductance regulator

124 loblasts express anion exchanger 2 (Ae2a,b), chloride channel Cftr, and amelogenins that can bind pro

125 ee proteins (ie, the water channel AQP1, the chloride channel CFTR, and the anion exchanger AE2) that

126 expression of adhesion molecule GlialCAM and chloride channel ClC-2, but no substantial changes in ot

127 oltage- and intracellular chloride-dependent chloride channel ClC-2.

128 The absence of the chloride channel CLC-3 in Clcn3(-/-) mice results in hip

129 The chloride channel CLC-3 is expressed in the brain on syna

130 by a conditional deletion of megalin or the chloride channel ClC-5 had constitutively enhanced AQP1

131 that of sodium-chloride cotransporter Nkcc, chloride channel ClC-Ka, and ClC-Ka/b accessory subunit

132 The chloride channel (CLC) family is distinctive in that som

133 nt CLCNKA gene, which encodes the K(a) renal chloride channel (ClC-K(a)).

134 investigate the role that the expression of chloride channels (ClC-1) plays on the age-dependent ele

135 tent with this, the expression of the muscle chloride channel, ClC-1, in Huntington disease muscle wa

136 ti-RAGE, reduces expression of intracellular chloride channel (CLIC)4, a scaffolding molecule necessa

137 LC-1, the alpha-subunit of a glutamate-gated chloride channel, confers resistance to avermectins in t

138 and glutamate uptake assays, we identified a chloride-channeling conformer, iChS, transiently accessi

139 ing significantly decreased Ca(2+)-dependent chloride channel currents activated in response to the n

140 t wild-type Arg83 and variant Gly83 ClC-K(a) chloride channel currents revealed approximately 50% los

141 ments show that Delta27-264 CFTR can restore chloride channel currents.

142 VNO and the requirement of calcium-activated chloride channels currents to mediate pheromone activati

143 In vertebrates, the chloride channel cystic fibrosis transmembrane conductan

144 is (CF) is caused by mutations in the apical chloride channel cystic fibrosis transmembrane conductan

145 Mutations of the chloride channel cystic fibrosis transmembrane conductan

146 Mutations in the chloride channel cystic fibrosis transmembrane regulator

147 ight be related to the basic cystic fibrosis chloride channel defect.

148 The calcium-dependent chloride channel DOG1 (ANO1/TMEM16A), which is strongly

149 ry subunit barttin might thus play a role in chloride channel dysfunction in certain variants of Bart

150 inding cassette transporters but serves as a chloride channel dysfunctional in cystic fibrosis.

151 this issue by showing that a plasma membrane chloride channel, encoded by ClC-a, is exclusively expre

152 Activation of the glutamate-gated chloride channel expressed in either rodent or human ind

153 d anoctamin 1 (ANO1), is a calcium-activated chloride channel expressed widely mammalian cells, inclu

154 ker ATF3 following prolonged glutamate-gated chloride channel expression.

155 inoids, the gamma-aminobutyric acid receptor/chloride channel for polychlorocyclohexanes and fiproles

156 sing channelrhodopsin-2 or a light-activated chloride channel for retrograde labelling, bidirectional

157 ively, and of the eukaryotic glutamate-gated chloride channel from Caenorhabditis elegans (GluCl), wh

158 n a living cell, utilizing a glutamate-gated chloride channel from the nematode Haemonchus contortus

159 bestrophin-1 (hBest1) is a calcium-activated chloride channel from the retinal pigment epithelium, wh

160 seawater is mediated by trafficking of CFTR chloride channels from intracellular vesicles to the pla

161 be mediated by ClC-Ka/K1 and ClC-Kb/K2, two chloride channels from the ClC family, or by KCl cotrans

162 p.I12T leaves chloride channel function unaffected and only interferes

163 tor (CFTR) that impair its expression and/or chloride channel function.

164 g defect that impairs protein maturation and chloride channel function.

165 rocessing and a "potentiator" to improve its chloride channel function.

166 fect that affects its processing and impairs chloride-channel function.

167 GABA-gated chloride channels (GABAARs) trafficking is involved in t

168 olding/cellular processing ("correctors") or chloride channel gating ("potentiators") have been disco

169 lar targeting to the plasma membrane and its chloride channel gating.

170 protein impairs its folding, stability, and chloride channel gating.

171 These were rs2228291, in the chloride channel gene CLCN2, and rs10513488, in the pota

172 ased on the structure of the glutamate-gated chloride channel GluCl of Caenorhabditis elegans.

173 ) and Caenorhabditis elegans glutamate-gated chloride channel (GluCl) for X-ray crystallography, demo

174 f the Caenorhabditis elegans glutamate-gated chloride channel (GluCl) in complex with the allosteric

175 termination of a structure of the eukaryotic chloride channel, GluCl, is an important step toward acc

176 Glutamate-gated chloride channels (GluCls) are found only in protostome

177 from selectively activating glutamate-gated chloride channels (GluCls) in invertebrates, not affecti

178 ceptors (GlyRs) and nematode glutamate-gated chloride channels (GluCls) recombinantly expressed in Xe

179 ixth transmembrane segment (TM6) of the CFTR chloride channel has been intensively investigated.

180 s transmembrane conductance regulator (CFTR) chloride channel, has been reported to regulate CFTR gat

181 s transmembrane conductance regulator (CFTR) chloride channel have identified several transmembrane s

182 Recently, calcium-activated chloride channels have been shown to contribute to VNO a

183 tions in CLCNKB, the gene encoding the renal chloride channel hClC-Kb, cause Bartter syndrome type II

184 signaling on CFTR or other calcium-activated chloride channels; here, we investigate the direct respo

185 in intact animals, using the histamine-gated chloride channel HisCl1 from Drosophila and exogenous hi

186 gineering of next-generation light-activated chloride channels (iC++) and a bistable variant (SwiChR+

187 t BEST1 assembles into a key calcium-sensing chloride channel in human RPE.

188 To test whether BEST1 functions as a chloride channel in living tissue, BEST1-mutant RPE (R21

189 s transmembrane conductance regulator (CFTR) chloride channel in many epithelia of the body.

190 onstituent of the vascular calcium-activated chloride channel in rat pulmonary artery smooth muscle.

191 e to loss-of-function mutations in the ClC-1 chloride channel in skeletal muscle, which causes involu

192 ity due to loss-of-function mutations in the chloride channel in skeletal muscle, which causes sponta

193 uggested that ClC-K2 is the main basolateral chloride channel in the thick ascending limb and in the

194 esults highlight the involvement of the ANO1 chloride channel in tumor progression and provide insigh

195 sults implicate variation in glutamate-gated chloride channels in avermectin resistance and provide a

196 escribed for its activity on glutamate-gated chloride channels in parasitic nematodes, understanding

197 It is thought to selectively activate type 2 chloride channels in the apical membrane of the intestin

198 ompounds acting, respectively, on sodium and chloride channels in the brain of fish.

199 ecifically implicated ClC-3, a voltage-gated chloride channel, in this process.

200 Several chloride channels including TMEM16, bestrophin, CFTR, CL

201 o function as the Ca(2+) activated secretory chloride channel independent of CFTR.

202 y 200 microm anthracene-9-carboxylic acid, a chloride channel inhibitor, and reduced concentrations o

203 limitations by introducing a dopamine-gated chloride channel into rat dorsal striatal medium spiny n

204 l Kb gene (CLCNKB), which encodes the ClC-Kb chloride channel involved in NaCl reabsorption in the re

205 ession of Gob5, a putative calcium-activated chloride channel involved in the regulation of mucus pro

206 s transmembrane conductance regulator (CFTR) chloride channel is a member of the ATP-binding cassette

207 conductance regulator (CFTR) plasma membrane chloride channel is the most common cause of cystic fibr

208 further show that inhibition by light-gated chloride channels is mediated mainly by shunting effects

209 ANO1, a calcium-activated chloride channel, is highly expressed and amplified in h

210 s transmembrane conductance regulator (CFTR) chloride channel, leading to defective apical chloride t

211 fibrosis is caused by mutations in the CFTR chloride channel, leading to reduced airway surface liqu

212 the dopamine transporter and the amine-gated chloride channel LGC-55 to generate behaviors in Caenorh

213 The inhibitory tyramine-gated chloride channel, LGC-55, induces head relaxation and in

214 diated through activation of the amine-gated chloride channel, LGC-55.

215 n through the activation of a tyramine-gated chloride channel, LGC-55.

216 in the Clcc1 gene, which encodes a putative chloride channel localized to the ER.

217 e to an effect at the nerve terminals, where chloride channels may play a more important role.

218 hannels, including CFTR and Ca(2+)-activated chloride channels mediate anion/fluid secretion.

219 been suggested to constitute a new family of chloride channels mediating Ca(2+)-dependent Cl- current

220 increases organelle pH, suggesting that the chloride channel might regulate melanin synthesis by mod

221 Here we show that a glutamate-gated chloride channel modified to be activated by low doses o

222 CFTR, the chloride channel mutated in cystic fibrosis (CF) patient

223 In CFTR, the chloride channel mutated in cystic fibrosis (CF) patient

224 onductance regulator (CFTR) is an epithelial chloride channel mutated in patients with cystic fibrosi

225 Thirty-two participants had chloride channel mutations, 34 had sodium channel mutati

226 cted to those with sodium channel mutations, chloride channel mutations, and myotonic dystrophy type

227 articipants, with warm up of myotonia in 75% chloride channel mutations, but also 35.3% of sodium cha

228 In comparison with chloride channel mutations, participants with sodium mut

229 s are helpful in differentiating sodium from chloride channel myotonia.

230 s transmembrane conductance regulator (CFTR) chloride channel occurs in these diarrheas.

231 ANO1/TMEM16A as the likely calcium-dependent chloride channel of exocrine glands has led to a more de

232 The chloride channel of the cystic fibrosis transmembrane co

233 of the structure, ligand-binding sites, and chloride channel of these receptors and discuss recently

234 ry effects of GABA-gated and serotonin-gated chloride channels on C. elegans behavior.

235 ory circuit, GABA release directly activates chloride channels on the muscle to cause muscle relaxati

236 sins: the proton pump, Archaerhodopsin and a chloride channel opsin.

237 s transmembrane conductance regulator (CFTR) chloride channels or both and whether action reflects in

238 ), and is tightly regulated by intracellular chloride channels or transporters.

239 ary technique using a native histamine-gated chloride channel (Ort).

240 uscle action potential amplitude in 59.3% of chloride channel participants compared with 27.6% of sod

241 s orthologues of the Drosophila pH-sensitive chloride channel (pHCl), CG8916 and CG12344.

242 Voltage-gated CLC-1 chloride channels play a critical role in controlling th

243 s transmembrane-conductance regulator (CFTR) chloride channel plays an important role in fluid and wa

244 stabilized by phosphorylation and binding of chloride channel potentiators.

245 ted activity on invertebrate glutamate-gated chloride channels, promotes neural differentiation of PS

246 ncreased autoantibody reactivity against the chloride-channel protein anoctamin 2 (ANO2) in MS cases

247 ne conductance regulator (CFTR) protein is a chloride channel regulating fluid homeostasis at epithel

248 Calcium-activated chloride channel regulator 1 (CLCA1) activates calcium-d

249 3, IL5, periostin (POSTN), calcium-activated chloride channel regulator 1 (CLCA1), and serpin peptida

250 an increased expression of calcium-activated chloride channel regulator 1 (CLCA1).

251 t impair the function of CFTR, an epithelial chloride channel required for proper function of the lun

252 CFTR protein biogenesis or its function as a chloride channel, resulting in dysregulation of epitheli

253 -type potassium channels and opening TMEM16A chloride channels, resulting in the production of nocice

254 ression of mPFC activity using an engineered chloride channel substantially reduced cataplexy induced

255 to Dieldrin gene, Rdl, encodes a GABA-gated chloride channel subunit that is targeted by cyclodiene

256 o mutations were detected in Glutamate-gated chloride channel subunits tested, suggesting target site

257 is provided for a role for calcium-activated chloride channels such as TMEM16a in GPCR-activation of

258 ugh interaction with other calcium-activated chloride channels, such as hBest2, 3, or 4, or transmemb

259 ia the allosteric modulation of ligand-gated chloride channels, such as hetero-oligomeric alpha1beta2

260 Gene functions included voltage and chloride channels, synapse-associated proteins, neurotra

261 nsmembrane conductance regulator (CFTR) is a chloride channel that belongs to the ATP binding cassett

262 ance regulator (CFTR) protein, an epithelial chloride channel that has a key role in maintaining homo

263 ectron microscopy reveals the structure of a chloride channel that is closely related to a protein th

264 ransmembrane conductance regulator (CFTR), a chloride channel that is essential for the mucociliary c

265 ANO1 is a calcium-activated chloride channel that is frequently overexpressed in hea

266 anion channel (VRAC) is a swelling-activated chloride channel that is permeable to inorganic anions a

267 ClC-2 is an inward-rectifying chloride channel that is thought to help extrude chlorid

268 nsmembrane conductance Regulator (CFTR) is a chloride channel that plays a critical role in the lung

269 Bestrophin 1 (hBest1) is a calcium-activated chloride channel that regulates neuronal excitability, s

270 d by Cftr) that impair its role as an apical chloride channel that supports bicarbonate transport.

271 O3, a gene encoding a predicted Ca(2+)-gated chloride channel that we show to be highly expressed in

272 (GABACR) and A (GABAAR) are both GABA-gated chloride channels that are distinguished by their distin

273 t advances on sodium, calcium, potassium and chloride channels that are emerging as especially attrac

274 de Caenorhabditis elegans three ligand-gated chloride channels that are receptors for biogenic amines

275 physiological functions of calcium-activated chloride channels that contain TMEM16A subunits.

276 Glycine receptors (GlyRs) are ligand-gated chloride channels that mediate inhibitory neurotransmiss

277 ceptors (GABA(A) receptors) are ligand-gated chloride channels that play a central role in signal tra

278 GABA(A) receptors (GABA(A)Rs), ligand-gated chloride channels that play an essential role in the con

279 deed, GABA(A) receptors not only function as chloride channels that regulate membrane voltage and con

280 s transmembrane conductance regulator (CFTR) chloride channel, the beta-2 adrenergic receptor (beta(2

281 spite of the many key cellular functions of chloride channels, the mechanisms that mediate their sub

282 Chloride influx through GABA-gated chloride channels, the primary mechanism by which neural

283 of the receptor-activated calcium-dependent chloride channel TMEM16A (TAOS2 or ANO1) has been report

284 sion of either CFTR or the calcium-activated chloride channel TMEM16A attenuated the proinflammatory

285 The calcium-activated chloride channel TMEM16A is a member of a conserved prot

286 The calcium-activated chloride channel TMEM16A is overexpressed in a variety o

287 KEY POINTS: The calcium-activated chloride channel TMEM16A provides a pathway for chloride

288 Targeted disruption of the calcium-activated chloride channel TMEM16A, also known as ANO1, in VSMCs,

289 selective inhibitor of the calcium-activated chloride channel TMEM16A, N-((4-methoxy)-2-naphthyl)-5-n

290 Calcium-activated chloride channels TMEM16A and TMEM16B support important

291 ssion/activity of reported calcium-activated chloride channels (TMEM16A, Bestrophin-1, ClC2, and SLC2

292 nt by opening the olfactory Ca(2+)-activated chloride channel to amplify the response.

293 lucidate a), the contribution of basolateral chloride channels to the short-circuit current functiona

294 n of genes encoding putative vacuolar NO3(-) chloride channel transporters plus electron micrographs

295 ts action is directly at one or the other of chloride channel type 2 (ClC-2) or cystic fibrosis trans

296 ClC-2 is a ubiquitous chloride channel usually localized to the basolateral do

297 rotype 9-based delivery, the glutamate-gated chloride channel was successfully targeted to mouse sens

298 Several voltage-gated chloride channels were also identified, although these m

299 ) is a cAMP/protein kinase A (PKA)-regulated chloride channel whose phosphorylation controls anion se

300 ClC-2 is a broadly distributed chloride channel with an enigmatic neurophysiological fu