ライフサイエンスコーパス: chlorobenzoate

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1 termediate of BP degradation and analogue of chlorobenzoates).

2 of the enzyme bound to the aryl substrate 4-chlorobenzoate.

3 he adenylate forming conformation bound to 4-chlorobenzoate.

4 nd 4-fluorobenzoate and mild inhibition by 3-chlorobenzoate, 2-chlorobenzoate, 4-hydroxybenzoate, 3-h

5 eudomonas palustris strain RCB100 degrades 3-chlorobenzoate (3-CBA) anaerobically.

6 L is poised to catalyze the adenylation of 4-chlorobenzoate (4-CB) with ATP (partial reaction 1), and

7 e and mild inhibition by 3-chlorobenzoate, 2-chlorobenzoate, 4-hydroxybenzoate, 3-hydroxybenzoate, an

8 the structures of I303 mutant complexes of 3-chlorobenzoate, a very poor substrate, revealed nonprodu

9 In Pseudomonas putida, benzoate and 3-chlorobenzoate are converted to catechol and 3-chlorocat

10 attention due to its ability to survive on 4-chlorobenzoate as its sole carbon source.

11 The structure of the 4-chlorobenzoate binding site is discussed in the context

12 ALP83, was carried out to determine if the 4-chlorobenzoate binding site of this enzyme can be transf

13 tic crystal, exemplified by 4-bromophenyl 4'-chlorobenzoate, by introduction of a molecular synthon -

14 A dehalogenase catalyzes the hydrolysis of 4-chlorobenzoate-CoA (4-CBA-CoA) to 4-hydroxybenzoyl-CoA (

15 The enzyme 4-chlorobenzoate-CoA dehalogenase catalyzes the hydrolysis

16 4-Chlorobenzoate:CoA ligase (CBAL) is a member of a family

17 4-Chlorobenzoate:CoA ligase (CBL) belongs to the adenylate

18 s issue we reported the X-ray structure of 4-chlorobenzoate:CoA ligase (CBL) bound with 4-chlorobenzo

19 Previously, we determined the structure of 4-chlorobenzoate:CoA ligase (CBL) in the adenylate forming

20 This study, which focuses on the 4-chlorobenzoate:CoA ligase (CBL) of the 4-monochlorobiphe

21 4-Chlorobenzoate:coenzyme A (4-CBA:CoA) ligase catalyzes 4

22 4-Chlorobenzoate:coenzyme A ligase (4-CBA:CoA ligase) cata

23 mutant shows a much slower growth rate on 4-chlorobenzoate compared to the wild type.

24 e literature and of strains derived from the chlorobenzoate-degrading Pseudomonas sp. strain B13 sugg

25 4-chlorobenzoyl-CoA, the first step in the 4-chlorobenzoate degredation pathway in PCB-degrading bact

26 coenzyme A (CoA) in the final step of the 4-chlorobenzoate dehalogenation pathway.

27 ns F199 and Sphingomonas yanoikuyae B1 and 2-chlorobenzoate dioxygenase from P. aeruginosa strains 14

28 te reduced catalysis of the adenylation of 4-chlorobenzoate in the mutant enzymes, are interpreted wi

29 of a byproduct, most likely N-succinimidyl 3-chlorobenzoate, increased with radiation dose.

30 The metabolic pathway by which 4-chlorobenzoate is degraded to 4-hydroxybenzoate in the s

31 volved in the hydrolytic dehalogenation of 4-chlorobenzoate is organized in the order fcbB-fcbA-fcbT1

32 Uptake of 4-chlorobenzoate is significantly inhibited by ionophores

33 4-Chlorobenzoate is transported into the wild-type strain

34 Transport of 4-chlorobenzoate shows significant inhibition by 4-bromo-,

35 ny ligands, or bound to the aryl substrate 4-chlorobenzoate, the enzyme adopts the conformation poise

36 al pathway by which this organism converts 4-chlorobenzoate to 4-hydroxybenzoate consists of three en

37 sform anthranilate and salicylate (but not 2-chlorobenzoate) to catechol.

38 tial reductive dechlorination step to form 4-chlorobenzoate was found in another coryneform bacterium

39 when P. putida is grown in the presence of 3-chlorobenzoate, which is converted to 3-chlorocatechol,

40 reaction consisting of the adenylation of 4-chlorobenzoate with adenosine 5'-triphosphate followed b

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