ライフサイエンスコーパス: chloromethylketone

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1 e protease inhibitor Nalpha-p-tosyl-l-lysine chloromethylketone.

2 protease inhibitor N-acetyl-Asp-Glu-Val-Asp-chloromethylketone.

3 ch BR mastocytoma cells with Ala-Ala-Pro-Phe-chloromethylketone (a chymase inhibitor) blocks profilin

4 tors screened, only decanoyl-Arg-Val-Lys-Arg-chloromethylketone, a known inhibitor for furin-type con

5 ensitive as nonselected cells to Ala-Ala-Phe-chloromethylketone, a specific inhibitor of tripeptidyl

6 The TPPII inhibitor Ala-Ala-Phe-chloromethylketone (AAF-cmk) and clasto-lactacystin beta

7 (acetyl-YVAD-CHO) and acetyl-Tyr-Val-Ala-Asp-chloromethylketone (acetyl-YVAD-CMK).

8 by EDTA, the suicide substrate decanoyl-RVKR-chloromethylketone, alpha1-antitrypsin Portland and by i

9 the furin inhibitor decanoyl-Arg-Val-Lys-Arg-chloromethylketone also diminished UTP-induced sAPP alph

10 As expected, decanoyl-Arg-Val-Lys-Arg-chloromethylketone also prevented the activation of MT5-

11 the inhibitors alanine-alanine-phenylalanine-chloromethylketone and butabindide, which are diagnostic

12 y in both D-phenylalanyl-L-prolyl-L-arginine chloromethylketone and citrate-anticoagulated blood earl

13 ditional functional handles, such as formyl, chloromethylketone, and iodide.

14 trate and D-phenylalanyl-L-prolyl-L-arginine chloromethylketone anticoagulants.

15 the caspase inhibitor acetyl-Tyr-Val-Ala-Asp chloromethylketone are subdivided and retested until a s

16 A furin inhibitor composed of decanoyl-RVKR-chloromethylketone blocked endosomal cleavage of the lar

17 either protein C nor boiled or D-Phe-Pro-Arg-chloromethylketone-blocked APC can induce microparticle

18 steady state fluorescence of fluorescein-EGR-chloromethylketone bound to the active site of thrombin.

19 intrinsic tenase complex was enhanced by EGR-chloromethylketone bound to the factor IXa active site o

20 ide-based S1P inhibitor, decanoyl (dec)-RRLL-chloromethylketone (CMK), and the prototypic arenavirus

21 rapeptide inhibitor N-acetyl-Asp-Glu-Val-Asp-chloromethylketone covalently bonded to the active site

22 ell-permeable enzyme inhibitor decanoyl-RRLL-chloromethylketone (dec-RRLL-CMK) not only suppressed pr

23 fic furin inhibitor decanoyl-Arg-Val-Lys-Arg-chloromethylketone (Dec-RVKR-cmk), and by calcium chelat

24 halene-1sulfonyl (dansyl) Glu-Gly-Arg-(DEGR)-chloromethylketone-factor Xa bound indistinguishably to

25 and treatment with decanoyl-Arg-Val-Lys-Arg-chloromethylketone indicate that the ADAMTS10 zymogen is

26 e of kexin (Kex2) in complex with a peptidyl-chloromethylketone inhibitor containing a noncognate lys

27 information, a mechanism-based tetrapeptide-chloromethylketone inhibitor was designed and shown to b

28 nactivation kinetics of Kex2 by two peptidyl chloromethylketone inhibitors demonstrates that the sele

29 with soybean trypsin inhibitor, Pro-Phe-Arg-chloromethylketone or PKSI 527 also shortens carotid art

30 de inhibitors of ICE (Acetyl-Tyr-Val-Ala-Asp-chloromethylketone) or CPP32beta (Acetyl-Asp-Glu-Val-Asp

31 ylketone (z-VAD.FMK), acetyl-Tyr-Val-Ala-Asp-chloromethylketone, or a relatively selective inhibitor

32 Addition of Phe-Pro-Arg-chloromethylketone (PPACK) to a complex of human alpha-t

33 Phe-Pro-Arg-chloromethylketone (PPACK), phosphate, and phosphonate e

34 inactive D-phenylalanyl-L-prolyl-L-arginine chloromethylketone (PPACK)-thrombin to L2H and L2H/V cel

35 te versus D-phenylalanyl-L-prolyl-L-arginine chloromethylketone (PPACK).

36 Only z-VAD.FMK and acetyl-Tyr-Val-Ala-Asp-chloromethylketone reduced brain swelling, and N-benzylo

37 he peptidyl inhibitor MeOSuc-Ala-Ala-Pro-Ala-chloromethylketone revealed a narrow and shallow S1 subs

38 d cells that are not replaced by Ala-Ala-Phe-chloromethylketone-sensitive proteases.

39 similar to the D-phenylalanyl-prolyl-arginyl chloromethylketone structure.

40 ng N-tosyl-<cmd SC>l<cmd /SC> -phenylalanine chloromethylketone (TPCK) or N-benzoyl-<cmd SC>l<cmd /SC

41 sin inhibitor and succinyl-L-Ala-Ala-Pro-Phe-chloromethylketone, which inhibit mast cell chymase, pre

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