ライフサイエンスコーパス: cholesterol esterase

1 g can produce highly selective inhibitors of cholesterol esterase.

2 resence of taurocholate, an activator of the cholesterol esterase.

3 hat were previously treated with the enzyme, cholesterol esterase (0.2 unit/mL).

4 cetylated LDL increased bile salt-stimulated cholesterol esterase activity in the conditioned media o

5 The structure of pancreatic cholesterol esterase, an enzyme that hydrolyzes a wide v

6 phages synthesized only bile salt-stimulated cholesterol esterase and not the hormone-sensitive lipas

7 The combination of cholesterol esterase and sphingomyelinase led to a signi

8 esults point to a synergistic effect between cholesterol esterase and sphingomyelinase, suggesting th

9 ide lipases is truncated in the structure of cholesterol esterase and therefore is not a salient feat

10 Plasma was digested with lipase and cholesterol esterase, and carotenoids were extracted and

11 r on reconstituted HDL was inhibited by anti-cholesterol esterase antibodies.

12 ding the inhibition of pancreatic lipase and cholesterol esterase, as well as cholesterol micelle for

13 The involvement of pancreatic cholesterol esterase (bile salt-stimulated lipase) in ch

14 The synthesis of bile salt-stimulated cholesterol esterase by human macrophages was confirmed

15 The expression of bile salt-stimulated cholesterol esterase by human macrophages, in a process

16 Inhibition of pancreatic cholesterol esterase by this series of pyrones was marke

17 minescence assay for total cholesterol using cholesterol esterase/cholesterol oxidase coupled with th

18 Treatment of LDL with cholesterol esterase converts LDL into cholesterol-rich

19 o and ex vivo samples were quantified with a cholesterol esterase enzymatic reaction.

20 Interactions of mammalian pancreatic cholesterol esterases from pig and rat with a family of

21 m cells to produce mice lacking a functional cholesterol esterase gene.

22 The physiologic role of the systemic cholesterol esterase has not been clearly defined.

23 sitive lipase (HSL), which acts as a neutral cholesterol esterase in macrophages and is a rate-limiti

24 nity of the carbamate for the active site of cholesterol esterase in the reversible, noncovalent comp

25 e demonstrate that both phospholipase A2 and cholesterol esterase increase cholesterol uptake by hydr

26 esults of the current study also showed that cholesterol esterase increased free-to-esterified choles

27 structure and composition contributes to the cholesterol esterase-induced cellular uptake of HDL-asso

28 This class of cholesterol esterase inhibitors functioned as simple com

29 Bile salt stimulated cholesterol esterase is predominantly synthesized in the

30 These results indicate that cholesterol esterase is responsible for mediating intest

31 ted carboxyl ester lipase (CEL), also called cholesterol esterase, is one of the major proteins secre

32 Cholesterol esterase knockout mice and their wild type c

33 These results suggest that liver-derived cholesterol esterase may play an important role in cellu

34 observations, we propose that liver-derived cholesterol esterase may play an important role in lipop

35 Cholesterol esterase-mediated transformation of LDL into

36 lipase mRNA but not the bile salt-stimulated cholesterol esterase mRNA.

37 significantly different between control and cholesterol esterase-null mice fed either control or an

38 radiolabel was detected in the serum of the cholesterol esterase-null mice in comparison with that d

39 results were similar between the control and cholesterol esterase-null mice regardless of whether the

40 d was found to be similar in the control and cholesterol esterase-null mice.

41 was used as a model to determine the role of cholesterol esterase on hepatic uptake of high density l

42 Carboxyl ester lipase (CEL, also called cholesterol esterase or bile salt-dependent lipase) is a

43 In the absence of cholesterol esterase or phospholipase A2, uptake of chol

44 ntanoyloxy)-8,8'-biquinolyl (4) with a crude cholesterol esterase preparation (from bovine pancreas)

45 ution crystal structure of bovine pancreatic cholesterol esterase (Rcryst = 21.1%; Rfree = 25.0% to 1

46 ction is n = 6 and n = 7 for porcine and rat cholesterol esterases, respectively, equivalent to eight

47 d recognition by the extended active site of cholesterol esterase that are prominent determinants of

48 monstrating the ability of exogenously added cholesterol esterase to further enhance hepatic uptake o

49 safety, tolerability and efficacy of a novel cholesterol esterase transfer protein (CETP) inhibitor T

50 hat cholesterol-rich liposomes produced from cholesterol esterase-treated LDL can cause human monocyt

51 ines were induced in normal PTS by exogenous cholesterol esterase treatment, proportionate lethal cel

52 Cholesterol oxidase and cholesterol esterase were assembled on the surface of gr

53 Selectivities for cholesterol esterase were greater than 10(3).

54 However, bile salt-stimulated pancreatic cholesterol esterase, which has been proposed to mediate

55 These haloesters were simple substrates of cholesterol esterase with no evidence of irreversible in

56 loped by integrating cholesterol oxidase and cholesterol esterase with the hybrid material.

57 onucleotide primers for bile salt-stimulated cholesterol esterase yielded positive reactions with RNA