ライフサイエンスコーパス: choline transporter

1 ryl-cholinesterase, nor of the high-affinity choline transporter.

2 -dependent, hemicholinium-3 (HC-3)-sensitive choline transporter.

3 icholinium-3 (HC-3)-sensitive, high affinity choline transporter.

4 and that snf-6 encodes a novel acetylcholine/choline transporter.

5 increases in the levels of the highaffinity choline transporter.

6 e presynaptic sodium-dependent high-affinity choline transporter 1 (CHT), which is known to be mutate

7 relatively unique in their expression of the choline transporter 1 (CHT1), which exhibits high-affini

8 se (AChE), choline acetyltransferase (ChAT), choline transporter 1 (CHT1, SLC5A7), vesicular acetylch

9 psis thaliana, 29.6% identity with the yeast choline transporter and 23.4% identity with the yeast UG

10 an increased expression of the high-affinity choline transporter and especially the muscarinic M2 rec

11 r presynaptic targeting of the high-affinity choline transporter and synaptic transmission.

12 The activity of the choline transporter and the hemicholinium-3 binding were

13 cerevisiae expresses a single high affinity choline transporter at the plasma membrane, encoded by t

14 gans encodes a high-affinity plasma-membrane choline transporter believed to be rate limiting for ace

15 mpared with evidence from NP rats, increased choline transporter capacity [as indicated by maximum tr

16 rom choline transported by the high-affinity choline transporter (CHT) and reduced ACh content relati

17 riation in the gene encoding the presynaptic choline transporter (CHT) has been linked to attention-d

18 The high-affinity choline transporter (CHT) is a protein integral to the f

19 sodium-dependent, hemicholinium-3-sensitive choline transporter (CHT) is believed to sustain acetylc

20 ion in SLC5A7, which encodes the presynaptic choline transporter (CHT), a critical determinant of syn

21 expression and activity of the high-affinity choline transporter (CHT), a molecule that mediates the

22 etyltransferase (ChAT) and the high-affinity choline transporter (ChT), as measured by reverse transc

23 on of the basal forebrain increased cortical choline transporter (CHT)-mediated choline transport in

24 nce indicating plastic mechanisms regulating choline transporter (CHT)-mediated high-affinity choline

25 ne transporter (VAChT) and the high-affinity choline transporter (CHT).

26 ARV), glutamic acid decarboxylase (GAD), and choline transporter (CHT).

27 be sustained by a hemicholinium-3-sensitive choline transporter (CHT).

28 a membrane, hemicholinium-3-sensitive (HC-3) choline transporter (CHT).

29 cular ACh transporter, and the high-affinity choline transporter CHT1.

30 oline transporter (VAChT), the high-affinity choline transporter (CHT1) and ChAT.

31 onal uptake of choline via the high affinity choline transporter (CHT1) is essential for cholinergic

32 Sodium-coupled, high-affinity choline transporters (CHTs) are inhibited by 3-morpholin

33 ies with mutants deficient in BetT and other choline transporters demonstrated that BetT was responsi

34 the presence of multiple known and putative choline transporters encoded within its genome.

35 evealed that changes were not due to altered choline transporter expression, but rather due to increa

36 ntiporter belonging to the betaine/carnitine/choline transporter family of secondary transporters.

37 cantly reduced, but not completely abrogated choline transporter function.

38 Here, we reported that a choline transporter gene, CTL1, controls ionome homeosta

39 The recent cloning of the human choline transporter (hCHT) has allowed its expression in

40 underscore the essential role played by the choline transporter in sustaining acetylcholine neurotra

41 the hypothesis that an increased capacity of choline transporters in the right medial prefrontal cort

42 The presynaptic, high-affinity choline transporter is a critical determinant of signall

43 We present details of how the choline transporter is a major regulator of phosphatidyl

44 , which labels the presynaptic high-affinity choline transporter, is responsive additionally to nerve

45 Characterizing choline transporter-like 1 (CTL1) as a new regulator of

46 tern blotting techniques, we have identified choline transporter-like 1 (CTL1) as a putative complexi

47 The choline transporter-like 1 (CTL1) protein is localized t

48 The choline transporter-like protein 1/solute carrier 44A1 (

49 pig peptides identical to sequences in human choline transporter-like protein 2 (CTL2).

50 stitution in the first extracellular loop of choline transporter-like protein 2, a member of the chol

51 direct evidence that anti-HNA-3a recognizes choline transporter-like protein 2.

52 1 encodes a member of a poorly characterized choline transporter-like protein family in plants and an

53 transporter-like protein 2, a member of the choline transporter-like protein family of membrane glyc

54 The CTL1 gene encodes a choline transporter-like protein with an expression patt

55 to transport choline, and the proportion of choline transporters localized in the membrane of synapt

56 a broad clinical phenotype due to homozygous choline transporter missense mutations.

57 l outcomes arising from different classes of choline transporter mutation with distinct disease proce

58 aptic terminals to acquire the high-affinity choline transporter necessary for high-frequency transmi

59 he trafficking of the Caenorhabditis elegans choline transporter orthologue revealed deficits in tran

60 Quantitative analysis of high-affinity choline transporter rates as a function of inhibitor and

61 ly conserved within the APC (amine-polyamine-choline) transporter superfamily.

62 ive frameshift mutation at the C-terminus of choline transporter that was associated with significant

63 report describes the relative roles of three choline transporters, the ABC transporter CbcXWV and two

64 Given the localization of the choline transporter to synaptic vesicles, we propose tha

65 ergic, activity-triggered delivery of silent choline transporters to the plasma membrane, in which no

66 molar conditions whereas BetT3 was the major choline transporter under hyperosmolar conditions.

67 itions, as BetT1 and CbcXWV were the primary choline transporters under hypo-osmolar conditions where

68 When POTS cells were treated with choline, transporter was up-regulated, and uptake of cho

69 uld directly interact with the high-affinity choline transporter which may impair steady-state and on