ライフサイエンスコーパス: chordoma

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1 erstone of management for chondrosarcoma and chordoma.

2 ine duplications of T that underlie familial chordoma.

3 ass, with biopsy confirming the diagnosis of chordoma.

4 in patients with unresectable or metastatic chordoma.

5 in a family with 10 individuals affected by chordoma.

6 ns in LYST, a potential novel cancer gene in chordoma.

7 ic driver landscape of 104 cases of sporadic chordoma.

8 profiles that were characteristic of primary chordomas.

9 evelopment and is expressed in most sporadic chordomas.

10 ed recurrence-free survival in patients with chordomas.

11 om January 2000 to May 2003, 51 patients (15 chordoma, 23 STS, 13 GIST patients) enrolled.

12 tiplex families with at least three cases of chordoma, a cancer of presumed notochordal origin.

13 an association study of 40 individuals with chordoma and 358 ancestry-matched controls, with replica

14 One patient (7%) with chordoma and one patient (4%) with STS had an objective

15 f this paper is to describe a case of clival chordoma and review recent developments in diagnostic an

16 anagement, and molecular characterisation of chordomas, and discuss current research.

17 Osteosarcoma (OS), chondrosarcoma, and chordoma are characterized by multiple challenges to the

18 Chordomas are rare tumors that can develop anywhere alon

19 Chordomas are thought to arise from transformed remnants

20 Chordomas are tumors that arise at vertebral bodies and

21 Chordomas are very rare bone malignant tumours that have

22 Chordomas can present a diagnostic challenge due to the

23 Eight human chordoma cell lines that we established exhibited cytolo

24 In this study, we addressed the need for chordoma cell systems that can be used to identify thera

25 , which may represent a novel cancer gene in chordoma.Chordoma is a rare often incurable malignant bo

26 eting on chordoma that included more than 40 chordoma experts from several disciplines and from both

27 routine for patients with chondrosarcoma and chordoma for whom surgery alone is inadequate.

28 with the contribution and sponsorship of the Chordoma Foundation, a global patient advocacy group.

29 ors investigate driver mutations of sporadic chordoma in 104 cases, revealing duplications in notocho

30 Chordoma is a malignant, often incurable bone tumour sho

31 Chordoma is a rare bone cancer that is aggressive, local

32 Chordoma is a rare malignant bone tumor that expresses t

33 Chordoma is a rare tumor originating from notochordal re

34 Treatment of clival chordomas is unique from other locations with an enhance

35 The gold standard treatment for chordomas of the mobile spine and sacrum is en-bloc exci

36 ion-free survival rates were 47% and 33% for chordoma patients, 26% and 22% for STS patients, and 31%

37 the common nonsynonymous SNP rs2305089 with chordoma risk (allelic odds ratio (OR) = 6.1, 95% confid

38 amptothecin (9-NC) in patients with advanced chordoma, soft tissue sarcoma (STS), and gastrointestina

39 progression was 9.9, 8.0, and 8.3 weeks for chordoma, STS, and GIST patients, respectively.

40 all, our work offers a valuable new tool for chordoma studies including the development of novel biom

41 also hosted a parallel consensus meeting on chordoma that included more than 40 chordoma experts fro

42 through an immunohistochemical analysis of a chordoma tissue bank of 43 patients.

43 w cell systems were highly representative of chordoma tissues.

44 These results map a locus for familial chordoma to 7q33.

45 This is the largest phase II study in chordoma to date.

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