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1 hat cause human diseases such as lymphocytic choriomeningitis, Bolivian hemorrhagic fever, and Lassa
2 murine gamma-herpesvirus 68 and lymphocytic choriomeningitis clone 13 and reversed T cell exhaustion
3 complexes formed during chronic lymphocytic choriomeningitis infection can interfere with Fcgamma-re
7 tion, including the well-studied lymphocytic choriomeningitis (LCMV) and Pichinde (PICV) viruses, sev
9 we have developed a recombinant lymphocytic choriomeningitis virus (LCMV) (rLCMVDeltaGP/GFP) where w
10 l known pathogenic arenaviruses, lymphocytic choriomeningitis virus (LCMV) and Lassa, Junin, Machupo,
11 C from the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) and LASV, which correlated
12 ith two natural mouse pathogens, lymphocytic choriomeningitis virus (LCMV) and murine cytomegalovirus
13 Prf1(--)) mice are infected with lymphocytic choriomeningitis virus (LCMV) and secondary (noninherite
14 e generated after infection with lymphocytic choriomeningitis virus (LCMV) and that these CD4 T cells
15 re we show that the arenaviruses lymphocytic choriomeningitis virus (LCMV) and the clinically used Ju
16 NPs) of the Old World arenavirus lymphocytic choriomeningitis virus (LCMV) and the New World arenavir
17 hmania major and 2 wk later with lymphocytic choriomeningitis virus (LCMV) and then monitored the cou
19 ections, such as infections with lymphocytic choriomeningitis virus (LCMV) and vaccinia virus, where
22 endrocyte glycoprotein (MOG) and lymphocytic choriomeningitis virus (LCMV) antigens, respectively.
24 ion with a persistent variant of lymphocytic choriomeningitis virus (LCMV) but have no impact on vira
28 f life-long chronic infection by lymphocytic choriomeningitis virus (LCMV) Cl 13 but does not affect
30 ly induced on APCs at day 2 post-lymphocytic choriomeningitis virus (LCMV) clone 13 infection, but is
31 T cells from mice infected with lymphocytic choriomeningitis virus (LCMV) clone 13 into recipient mi
32 During chronic infection with lymphocytic choriomeningitis virus (LCMV) clone 13, miR-31-deficent
33 with that of a persistent virus, lymphocytic choriomeningitis virus (LCMV) clone 13, on early innate
34 urs after mice are infected with lymphocytic choriomeningitis virus (LCMV) clone 13, which is used as
37 ic event are more susceptible to lymphocytic choriomeningitis virus (LCMV) clone-13 infection exhibit
38 mice with Coxsackie virus B3 or lymphocytic choriomeningitis virus (LCMV) delayed diabetes onset and
39 mice persistently infected with lymphocytic choriomeningitis virus (LCMV) exhibit a severe defect in
40 we found that mice infected with lymphocytic choriomeningitis virus (LCMV) exhibit global perturbatio
41 eficient animals failed to clear lymphocytic choriomeningitis virus (LCMV) from hematopoietic organs
42 unized with H(2)O(2)-inactivated lymphocytic choriomeningitis virus (LCMV) generated cytolytic, multi
43 d mice with Ad5 vectors encoding lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP) and exam
44 denovirus vectors expressing the lymphocytic choriomeningitis virus (LCMV) glycoprotein (GP), followe
46 wever, the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) has proven to be a Rosetta
47 and CD8(+) T cells responding to lymphocytic choriomeningitis virus (LCMV) identified multiple genes
48 acute primary infection with the lymphocytic choriomeningitis virus (LCMV) in mice is significantly f
51 nges the outcome to a subsequent lymphocytic choriomeningitis virus (LCMV) infection and can result i
52 rus-specific CTLs during chronic lymphocytic choriomeningitis virus (LCMV) infection and suppressed C
53 fied during chronic versus acute lymphocytic choriomeningitis virus (LCMV) infection and suppresses T
54 Although much is known about lymphocytic choriomeningitis virus (LCMV) infection and the subseque
55 f IAPs in T-cell immunity during lymphocytic choriomeningitis virus (LCMV) infection by pharmacologic
56 hough cellular immunity to acute lymphocytic choriomeningitis virus (LCMV) infection has been well ch
57 ction over the course of chronic lymphocytic choriomeningitis virus (LCMV) infection in an IL-10 repo
59 e to establishment of persistent lymphocytic choriomeningitis virus (LCMV) infection in mice through
65 Recently, several cases of fatal lymphocytic choriomeningitis virus (LCMV) infection occurred in tran
66 n kinetics and viral loads after lymphocytic choriomeningitis virus (LCMV) infection of Ctx(-) mice.
67 ramatic at 2 to 4 days following lymphocytic choriomeningitis virus (LCMV) infection of mice and can
69 we used a mouse model of chronic lymphocytic choriomeningitis virus (LCMV) infection to address this
70 rom aseptic meningitis following lymphocytic choriomeningitis virus (LCMV) infection to hemorrhagic f
71 CD8(+) T-cell response to acute lymphocytic choriomeningitis virus (LCMV) infection was predominantl
72 erentiated CD8(+) T cells during lymphocytic choriomeningitis virus (LCMV) infection, and Blimp-1 def
73 during the first week of chronic lymphocytic choriomeningitis virus (LCMV) infection, before severe d
74 are essential for clearance of a lymphocytic choriomeningitis virus (LCMV) infection, but the virus c
75 t al. report that in response to lymphocytic choriomeningitis virus (LCMV) infection, fully different
77 ormation following immunization, lymphocytic choriomeningitis virus (LCMV) infection, or herpes simpl
78 pathology during early systemic lymphocytic choriomeningitis virus (LCMV) infection, suggesting a ho
88 istributed prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) is a neglected human patho
89 istributed prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) is a neglected human patho
90 istributed prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) is a neglected human patho
91 istributed prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) is an important neglected
93 hronic Clone 13 (C13) strains of lymphocytic choriomeningitis virus (LCMV) led to two distinct phases
94 Ins2-GP(Tg) mice injected with lymphocytic choriomeningitis virus (LCMV) lost islet sympathetic ner
96 of the Old World (OW) arenavirus lymphocytic choriomeningitis virus (LCMV) or Lassa virus, bind to RI
98 C (BMDC) that were infected with lymphocytic choriomeningitis virus (LCMV) or loaded with an immunodo
99 at infection of mice with either lymphocytic choriomeningitis virus (LCMV) or pneumonia virus of mice
100 tion with the systemic pathogens lymphocytic choriomeningitis virus (LCMV) or vaccinia virus (VACV).
101 using RIP-LCMV mice expressing a lymphocytic choriomeningitis virus (LCMV) protein in the beta-cells.
102 low-dose infection of mice with lymphocytic choriomeningitis virus (LCMV) results in massive expansi
104 tigen variant-expressing chronic lymphocytic choriomeningitis virus (LCMV) strains, we uncovered that
105 mice persistently infected with lymphocytic choriomeningitis virus (LCMV) suppressed multiple Fcgamm
107 stently infected from birth with lymphocytic choriomeningitis virus (LCMV) to demonstrate that therap
108 e used the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) to develop a general molec
109 nant engineering of trisegmented lymphocytic choriomeningitis virus (LCMV) to express two genes of in
110 prototypic Old World arenavirus lymphocytic choriomeningitis virus (LCMV) to interfere with RIG-I/MA
111 ity of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) to interfere with the indu
112 viral nucleoprotein (NP) gene of lymphocytic choriomeningitis virus (LCMV) was expressed in the thymu
113 NP) of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV) with the least frequently
114 NP of the prototypic arenavirus lymphocytic choriomeningitis virus (LCMV), as well as those of the h
115 y molecule expression induced by lymphocytic choriomeningitis virus (LCMV), CD28/B7-mediated costimul
116 prototype member in the family, lymphocytic choriomeningitis virus (LCMV), disables the host innate
117 rf1(-/-)) mice are infected with lymphocytic choriomeningitis virus (LCMV), disease is driven by over
119 stributed prototypic arenavirus, lymphocytic choriomeningitis virus (LCMV), is a neglected human path
120 ting mice with L. guyanensis and lymphocytic choriomeningitis virus (LCMV), or the sand fly-transmitt
122 ding Ebola virus, Marburg virus, lymphocytic choriomeningitis virus (LCMV), rabies virus, and Lassa v
124 in memory phase challenged with lymphocytic choriomeningitis virus (LCMV), which we show in this stu
126 is also partially controlled in lymphocytic choriomeningitis virus (LCMV)-immune C57BL/6J mice throu
127 (AP)-fed controls, LP feeding in lymphocytic choriomeningitis virus (LCMV)-immune mice resulted in a
131 sion of CCL21 in murine spleens, lymphocytic choriomeningitis virus (LCMV)-specific T cell responses
156 th a variant glycoprotein of the lymphocytic choriomeningitis virus (LCMV-GP), creating a replicating
157 urine cytomegalovirus (MCMV) and lymphocytic choriomeningitis virus (LCMV; Cl13), in their natural ro
159 ollowed by replication-defective lymphocytic choriomeningitis virus (rLCMV) boost elicited robust CD4
161 nts of the prototypic arenavirus lymphocytic choriomeningitis virus (rLCMVs), whose S-IGRs were repla
162 on CD8(+) T cells during chronic lymphocytic choriomeningitis virus and hepatitis C virus infections.
163 s also required for infection of lymphocytic choriomeningitis virus and human parainfluenza virus typ
164 expand and to protect from acute lymphocytic choriomeningitis virus and Leishmania major parasite inf
165 cribe its use in the contexts of lymphocytic choriomeningitis virus and Mycobacterium tuberculosis in
166 ell responses to infections with lymphocytic choriomeningitis virus and the intracellular bacteria Li
167 marenaviruses, the widely spread lymphocytic choriomeningitis virus and the recently described Wenzho
168 ve CD8+ T cells recognizing both lymphocytic choriomeningitis virus and vaccinia virus antigens.
170 n H-2K(b) carrying peptides from lymphocytic choriomeningitis virus and vaccinia virus, and used thes
171 f a naive C57BL/6 recipient with lymphocytic choriomeningitis virus and vaccinia virus, followed by c
172 owed enhanced viral clearance in lymphocytic choriomeningitis virus and vesicular stomatitis virus in
173 rtantly, anti-CD137 treatment of lymphocytic choriomeningitis virus Armstrong infected Stat3 conditio
174 administered at the beginning of lymphocytic choriomeningitis virus Armstrong infection anti-CD137 in
175 expression in vivo during acute lymphocytic choriomeningitis virus Armstrong infection, which induce
178 Ns, and in persistently infected lymphocytic choriomeningitis virus carrier mice, which contain low l
179 T cells during acute and chronic lymphocytic choriomeningitis virus challenges, but did not affect th
181 or nonhematopoietic cells during lymphocytic choriomeningitis virus clone 13 (LCMV CL-13) infection.
182 that the Old World arenaviruses lymphocytic choriomeningitis virus clone 13 (LCMV Cl13) and Lassa vi
184 d prevented chronic infection in lymphocytic choriomeningitis virus clone 13- and reduced viral load
186 ns expressing well-characterized lymphocytic choriomeningitis virus epitopes, we found that survival
187 adenovirus vector expressing the lymphocytic choriomeningitis virus glycoprotein (LCMVgp) (Ad5gp) inc
189 ne responses to acute and chronic lymphocyte choriomeningitis virus infection are regulated by type 1
190 normal acute response (day 8) to lymphocytic choriomeningitis virus infection but generated an increa
191 with this finding, we show that lymphocytic choriomeningitis virus infection can directly modulate t
192 e with rapamycin following acute lymphocytic choriomeningitis virus infection enhanced not only the q
193 responses to acute or persistent lymphocytic choriomeningitis virus infection in IFN-lambdaR1-deficie
194 ls are comparable in controlling lymphocytic choriomeningitis virus infection in mice and suppress gr
195 TGF-beta receptor during chronic lymphocytic choriomeningitis virus infection in mice, and determined
196 cell dysfunction during chronic lymphocytic choriomeningitis virus infection in mice, and PD-1(hi) c
202 (+) T cell subpopulations in the lymphocytic choriomeningitis virus infection model, we found that th
203 a murine model of HLH, involving lymphocytic choriomeningitis virus infection of perforin-deficient m
204 sic manner early following acute lymphocytic choriomeningitis virus infection to suppress the magnitu
205 ss of vaccination against lethal lymphocytic choriomeningitis virus infection using plasmid DNA in a
207 show that during chronic murine lymphocytic choriomeningitis virus infection, activation of AKT and
208 ced viral clearance in models of lymphocytic choriomeningitis virus infection, and also protection fr
209 ring the early stages of chronic lymphocytic choriomeningitis virus infection, and that this early T
210 in immunization; however, during lymphocytic choriomeningitis virus infection, B cells induce T(FH) d
213 gulated during memory to chronic lymphocytic choriomeningitis virus infection, limiting functional ca
215 in response to vaccinia virus or lymphocytic choriomeningitis virus infection, more Ag-specific memor
216 the experimental mouse model of lymphocytic choriomeningitis virus infection, we demonstrate that th
218 (+) T cells to acute and chronic lymphocytic choriomeningitis virus infection, we show that memory ce
219 CD4 T cells at days 2 to 3 after lymphocytic choriomeningitis virus infection, when type I IFN levels
220 ls to mount a robust response to lymphocytic choriomeningitis virus infection, with both quantitative
221 reased cytokine production after lymphocytic choriomeningitis virus infection, yet DGK-deficient memo
234 RM subsets was overcome by acute lymphocytic choriomeningitis virus infection; nevertheless, memory v
235 y also show that chronic HIV and lymphocytic choriomeningitis virus infections have a very different
238 tion during primary responses to lymphocytic choriomeningitis virus lowered the magnitude of CD8 Ag-s
239 ve upon this, we used the murine lymphocytic choriomeningitis virus model and adenoviral vectors to c
240 ivation was also verified in the lymphocytic choriomeningitis virus model, in which IFN-beta promoter
241 by two other NS RNA viruses, the lymphocytic choriomeningitis virus of the Arenaviridae family and hu
242 the impact of an infection with lymphocytic choriomeningitis virus on prenatal allospecific toleranc
243 protracted viral infection with lymphocytic choriomeningitis virus or during autoimmune diabetes dev
244 cell cycle after infection with lymphocytic choriomeningitis virus or vesicular stomatitis virus.
245 r stomatitis virus, reovirus, or lymphocytic choriomeningitis virus replication but protected against
246 ot acute, infection of mice with lymphocytic choriomeningitis virus results in a marked expansion of
247 ction of Spi6 knockout mice with lymphocytic choriomeningitis virus revealed impaired survival of CD8
248 is cell turnover, we transferred lymphocytic choriomeningitis virus specific memory CD8 T cells into
249 ponses in mice given variants of lymphocytic choriomeningitis virus that cause acute or persisting in
250 in mice lacking B cells, whereas lymphocytic choriomeningitis virus titers were dramatically increase
251 We infected FtDKO mice with lymphocytic choriomeningitis virus to generate and track Ag-specific
252 gainst representative Old World (lymphocytic choriomeningitis virus) and New World (Junin virus) aren
253 detected in cells infected with lymphocytic choriomeningitis virus, an ambisense RNA virus, and minu
254 for vesicular stomatitis virus, lymphocytic choriomeningitis virus, and dengue virus but not for the
256 found that in mice infected with lymphocytic choriomeningitis virus, colocalization of virus-specific
257 After infection of mice with lymphocytic choriomeningitis virus, IL-2Ralpha-deficient effector CD
258 murine CMV (MCMV), but not with lymphocytic choriomeningitis virus, induce CD25 on NK cells, along w
259 mice with Coxsackie virus B3 or lymphocytic choriomeningitis virus, neither of which directly destro
260 iciently promote CD8 immunity to lymphocytic choriomeningitis virus, nor did cav-1(-/-) OT-1(+) CD8(+
261 ss-reactive with three different lymphocytic choriomeningitis virus, one Pichinde virus, or one other
263 phase of an acute infection with lymphocytic choriomeningitis virus, we found that virus-specific CD8
264 fluenza hemagglutinin or GP from lymphocytic choriomeningitis virus, which enter through late endosom
265 The clone 13 (Cl13) variant of lymphocytic choriomeningitis virus--a prototype of Old World arenavi
266 es occur upon stimulation with a lymphocytic choriomeningitis virus-derived escape mutant as demonstr
267 ring splenocytes from individual lymphocytic choriomeningitis virus-immune donors into paired recipie
268 of panniculitis are observed in lymphocytic choriomeningitis virus-immune mice after vaccinia virus
269 es development in the CD8-driven lymphocytic choriomeningitis virus-induced model of type 1 diabetes.
270 dual role in the development of lymphocytic choriomeningitis virus-induced, T cell-mediated hepatiti
271 e highly dynamic model system of lymphocytic choriomeningitis virus-mediated hepatitis and bone marro
272 ther germinal center B cells nor lymphocytic choriomeningitis virus-specific Ab levels were influence
273 fic human CD8 T cells or chronic lymphocytic choriomeningitis virus-specific CD8 T cells from mice; 3
274 ty (approximately 65% to 80%) of lymphocytic choriomeningitis virus-specific CD8 T cells in lymphoid
275 al T-cell functions, "exhausted" lymphocytic choriomeningitis virus-specific cells losing the capacit
276 nsion of both primary and memory lymphocytic choriomeningitis virus-specific CTL, which could be corr
277 cells and the systemic levels of lymphocytic choriomeningitis virus-specific IgG2 Abs were dramatical
279 ection, Cmah(-/-) mice make more lymphocytic choriomeningitis virus-specific T cells than WT mice, an
280 gnaling blockade on the residual lymphocytic choriomeningitis virus-triggered CTL response detected i
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