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2 osomally normal female (n = 38), nontrisomic chromosomally abnormal (n = 61)-to the distribution for
4 dary analyses, we subdivided the nontrisomic chromosomally abnormal group, divided trisomies by chrom
10 ividuals that were karyotyped, 23 (62%) were chromosomally additive of the parents, whereas the remai
13 k duplications identified all occurred intra-chromosomally, and all but one occurred quite recently.
16 tulated that the subcellular position of the chromosomally associated replisome is established by the
19 e relative usage of V and J gene segments is chromosomally biased, with approximately 1.5 times as ma
21 moniae, the MrkD adhesin is located within a chromosomally borne gene cluster and mediates binding to
22 Sequences located proximal to the two other chromosomally carried haloarchaeal orc genes (orc6 and o
24 sterility from the two Solanum studies were chromosomally colocalized, indicating a shared evolution
25 were associated with increased incidence of chromosomally defective sperm, raising concerns for work
26 This significantly increases the number of chromosomally defined genetic markers for this species a
27 r induced antisense RNA could interfere with chromosomally derived gene expression, we cloned a fragm
28 has been developed and used to downregulate chromosomally derived genes expressed in Staphylococcus
30 that these differences are a function of the chromosomally determined sexual identity of shared neura
36 ate here that one putative highly conserved, chromosomally encoded adhesin, EaeH, engages the surface
37 quorum-sensing system controls production of chromosomally encoded alpha-toxin and perfringolysin O b
40 f toxin systems with the SUKH superfamily is chromosomally encoded and appears to have diversified th
42 results in substantial derepression of both chromosomally encoded and plasmid-encoded hilA::Tn5lacZY
43 nce of the virulence plasmid, suggesting the chromosomally encoded and plasmid-encoded type III secre
46 operon of Escherichia coli is a paradigm for chromosomally encoded antibiotic resistance in enteric b
56 s all Escherichia coli tRNA transcripts have chromosomally encoded CCA determinants, the function of
58 consistent with the emerging picture of the chromosomally encoded copper homeostasis apparatus in th
60 o intracellular Fe(2+) concentration, by the chromosomally encoded diphtheria toxin repressor (DtxR).
63 ated a transgenic parasite line expressing a chromosomally encoded DPAP1-green fluorescent protein fu
64 most antibiotic classes, which results from chromosomally encoded drug-efflux systems and multiple a
65 previously identified the protein Tet38 as a chromosomally encoded efflux pump of Staphylococcus aure
66 n S. aureus, NorA, NorB, NorC, and Tet38 are chromosomally encoded efflux pumps whose overexpression
70 pecific activities were greater than that of chromosomally encoded FadD, they were unable to substitu
73 sistance that is caused by the presence of a chromosomally encoded gene (blaC) in Mycobacterium tuber
74 eir resistance genes on plasmids, unlike the chromosomally encoded genes of DT104 isolates, which cou
75 tion of the phage-encoded tox gene, and many chromosomally encoded genes, is regulated by the DtxR pr
77 A endonuclease and is the first example of a chromosomally encoded group I intron endonuclease in bac
81 The inositol catabolism genes comprise the chromosomally encoded iolA (mmsA) and the iolY(smc01163)
82 lymerase chain reaction assays at either the chromosomally encoded level, or at an elevated level enc
84 encoding bacteriophage autolytic enzymes and chromosomally encoded lytA might be important in the evo
85 homologous to the signal sensor domain of a chromosomally encoded major sporulation sensor histidine
86 which we name [MCA], was transmitted to the chromosomally encoded Mca1p based on genetic, cytologica
88 can be identified in a substantial number of chromosomally encoded mRNAs and that they occur with fre
90 ichia coli strains so far examined possess a chromosomally encoded nanATEK-yhcH operon for the catabo
92 plifications encompassing or SNPs within the chromosomally encoded organellar (apicoplast) isoleucyl-
97 stems) based on the sequence analysis of the chromosomally encoded polymorphic repeat X region of the
98 or pilus subunit, PilS2, is processed by the chromosomally encoded prepillin peptidase PilD but not i
103 e isolation and characterization of a novel, chromosomally encoded protein, EbfC, that binds specific
104 Formaldehyde cross-linking of the endogenous chromosomally encoded proteins in Y. enterocolitica reve
105 A yeast two-hybrid screen searching for chromosomally encoded proteins that interact with the Ag
112 llance during outgrowth and replication) and chromosomally encoded sporulation (required only during
117 ke proteins from mobile genetic elements and chromosomally encoded T4SS from G+ and G- bacteria, we p
120 A two-gene operon, HipBA, is one of many chromosomally encoded toxin and antitoxin modules in Esc
124 y or phospholipase activity, suggesting this chromosomally encoded type III secretion pathway is dist
125 genic Yersinia enterocolitica strains have a chromosomally encoded type III secretion system (T3SS) t
127 We also found that S. flexneri contained a chromosomally encoded umuDC operon; however, the umuDC p
130 overproduced mutant enzymes from coexpressed chromosomally encoded wild-type DMAPP-tRNA transferase.
133 e factor is the constitutive production of a chromosomally encoded, Ambler class A beta-lactamase, Bl
134 ta-lactam class of antibiotics arises from a chromosomally encoded, extended spectrum, class A beta-l
136 In order to determine the function of this chromosomally-encoded secretion apparatus, we created an
140 ta analysis revealed that in the presence of chromosomally expressed GreA, 19 genes are upregulated;
141 Caulobacter crescentus and Escherichia coli, chromosomally expressed mRNAs largely display limited di
142 ells collaborated successfully with diplo-X (chromosomally female) germ cells to make functional eggs
144 origin function of these silencer-associated chromosomally inactive origins differ from the sequences
145 result from directed gene rearrangements and chromosomally inherited epigenetic gene control mechanis
146 is strain contained six phage-encoded and 24 chromosomally inherited well-known virulence factors, as
151 thin SLP1(int) represses replication of both chromosomally integrated and extrachromosomal SLP1.
152 nd 33277 tested positive for the transfer of chromosomally integrated antibiotic resistance markers.
154 hromatin structures of the hTERT promoter in chromosomally integrated BAC reporter recapitulated its
157 urthermore, rtTA2S-M2 expressing clones with chromosomally integrated copies of a TRE-green fluoresce
158 pproximately 1% of the population inherits a chromosomally integrated copy of human herpesvirus 6 (CI
161 ot HMGA1a-DBD activated transcription from a chromosomally integrated EBNA1-dependent transcription r
167 es are found both as extrachromosomes and as chromosomally integrated forms in hepatocytes, the relat
168 Inter actions between FLP monomers bound to chromosomally integrated FRT sites were unimpeded by eit
171 ble human hepatoma cell lines that contain a chromosomally integrated genotype 2a HCV cDNA and consti
173 IX (hF.IX) levels in mice originating from a chromosomally integrated hF.IX-expressing transposon vec
174 ) infection results from germline passage of chromosomally integrated HHV-6 (CI-HHV-6) and from trans
175 About 1% of people worldwide are carriers of chromosomally integrated HHV-6 (ciHHV-6), which is inher
177 pidemiology and clinical effect of inherited chromosomally integrated HHV-6 (iciHHV-6) in hematopoiet
179 ere, we used normal human fibroblasts with a chromosomally integrated HR reporter cassette to examine
180 alysis of factors required for expression of chromosomally integrated HTLV-1 LTR has not been done.
187 By using a transgenic mouse model with a chromosomally integrated lacZ reporter gene, mutational
188 icient mice with transgenic mice harboring a chromosomally integrated lacZ-plasmid reporter construct
189 s two lines of transgenic mice that have the chromosomally integrated lambdasupFG1 shuttle-reporter t
190 enomic libraries in an E. coli strain with a chromosomally integrated Lpl rpoD enables the identifica
191 urst generates a novel progeny population of chromosomally integrated LTR retrotransposons consisting
192 tations that inactivate two genes encoded on chromosomally integrated MGEs recover these fitness cost
195 Finally, this lack of binding of c-Myb to a chromosomally integrated mutant RAG-2 promoter construct
196 hen S. enterica serovar Typhimurium with the chromosomally integrated PA gene was given intravenously
198 ge, autonomously replicating plasmid or have chromosomally integrated plasmid-like sequences (IPS), s
199 in addition to producing these 'classical', chromosomally integrated products, a fungal L1 clade mem
200 (TBP) activates transiently transfected and chromosomally integrated promoters with equal efficiency
201 ains are less effective when the promoter is chromosomally integrated rather than transiently transfe
203 transcription of transiently transfected and chromosomally integrated reporter genes by the estrogen
207 Xvarphi prophage often resides adjacent to a chromosomally integrated satellite phage genome, RS1, wh
212 show that T7RNAP-mediated transcription from chromosomally integrated T7 promoters is repressed along
213 , the basal transcriptional machinery, and a chromosomally integrated template responsive to the acet
215 including the largest gene circuit built and chromosomally integrated to date (6 transcription units,
216 transposon mutants of V. cholerae carrying a chromosomally integrated toxT::lacZ reporter construct f
217 of gene expression in yeast cells harboring chromosomally integrated transcriptional cascades that c
219 is challenged by HIV latency, the ability of chromosomally integrated virus to persist within memory
220 regulation of SCL CS activity in organized (chromosomally integrated) and disorganized (non-replicat
221 oman was, however, a carrier of an inherited-chromosomally-integrated human herpesvirus-6A (iciHHV-6A
223 by a 62 kb self-transmissible, conjugative, chromosomally integrating element designated the 'SXT el
224 element is a conjugative self-transmissible chromosomally integrating element that encodes resistanc
225 hort-range chromosome fiber features such as chromosomally interacting domains and higher order featu
226 striking kinetics, activated HSP genes, both chromosomally linked and unlinked, coalesce into discret
227 acterial species, the encoding glpR gene was chromosomally linked with genes of sugar metabolism.
228 450 of the sterol demethylase family (CYP51) chromosomally located adjacent to a ferredoxin (Fdx).
229 The resistance transfer mechanisms of the chromosomally located erythromycin rRNA methylase gene e
230 ototypical members of a widespread family of chromosomally located mobile genetic elements that contr
232 ed tetranucleotide (5'AGTC) repeat tracts of chromosomally located reporter constructs, whereas inact
233 We employed a strain that contained two chromosomally located reporter genes under the control o
235 into a B. burgdorferi host strain carrying a chromosomally located tetR under the control of the B. b
236 g rates for these tracts were measured using chromosomally-located reporter constructs and high rates
237 erent cultivars of lettuce inoculated with a chromosomally lux-marked strain of E. coli O157:H7.
238 Tra(F) transgene, functionally Sxl- haplo-X (chromosomally male) somatic cells collaborated successfu
240 the mtrCDE-encoded efflux pump in conferring chromosomally mediated penicillin resistance on certain
241 le containing an A501V mutation to FA6140, a chromosomally mediated penicillin-resistant isolate, inc
242 The most common QRNG ASLGP strain type had chromosomally mediated resistance to penicillin and tetr
243 lved in the capacity of gonococci to develop chromosomally mediated resistance to penicillin G, which
244 overed, including a role for Mi-2 antigen in chromosomally-mediated regulation of transcription as pa
246 after intradermal delivery of the PNA-Antp, chromosomally modified, keratin 5-positive basal keratin
247 corresponding ICs shows that, compared with chromosomally nonadjacent metabolic neighbors, DNGPs are
248 disequilibrium to markers in this region in chromosomally normal autism families indicate the existe
252 = 154), chromosomally normal male (n = 43), chromosomally normal female (n = 38), nontrisomic chromo
254 wo groups: women whose index pregnancy was a chromosomally normal loss (n=157) and women whose index
255 trisomic losses than it was among women with chromosomally normal losses and chromosomally normal bir
256 in four karyotype groups-trisomy (n = 154), chromosomally normal male (n = 43), chromosomally normal
258 st-trimester chorionic villi was assessed in chromosomally normal miscarriages from women with RM (N
261 human DNA replication in an allele-specific, chromosomally phased manner, we determined for the first
262 e polymorphisms (SNPs), but the relevance of chromosomally phased SNPs (haplotypes) is not known.
263 ent, the targeting plasmid recombines at the chromosomally preconfigured FRT site, and a new hemizygo
264 tiotemporal distribution of a functional and chromosomally produced CckA-monomeric green fluorescent
265 known about KatY, except that it is encoded chromosomally, produced in abundance, possesses modest c
268 The anaplastic lymphoma kinase (ALK) is chromosomally rearranged in a subset of certain cancers,
270 roductive cell death, we analyzed subsets of chromosomally stable and unstable clones for relationshi
271 tistical analyses performed on each group of chromosomally stable and unstable clones indicated that,
273 hereas artificially inducing GTSE1 levels in chromosomally stable cells elevates chromosome missegreg
274 chromosomally unstable clones than it was in chromosomally stable clones (P < 0.05; ANOVA and Student
276 ingly, transdifferentiated cells seemed more chromosomally stable, except if they were reprogrammed u
277 ion of yeast strains expressing full-length, chromosomally tagged green fluorescent protein fusion pr
280 was observed in the context of the natural, chromosomally translocated, and amplified gene locus.
282 s, we discovered that a protein encoded by a chromosomally unlinked gene, espA, is also secreted by s
284 cell lines, previously classified as either chromosomally unstable (CIN(+)) or diploid/near-diploid
286 uploidy in primary cells are also present in chromosomally unstable cancer cell lines, but the same a
290 A strand breaks, was significantly higher in chromosomally unstable clones than it was in chromosomal
291 10115 cells die when cultured in medium from chromosomally unstable GM10115 clones is the death-induc
292 However, growth medium conditioned by some chromosomally unstable RKO derivatives induced genomic i
295 tion, Artemis mutants are radiosensitive and chromosomally unstable, which has been attributed to a d
297 often have meiotic irregularities, producing chromosomally variable gametes and progeny; however, lit
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