ライフサイエンスコーパス: chromosome 15

1 BALB/cJ trait had been mapped to a locus on chromosome 15.

2 encoded in a cluster of paralogous genes on chromosome 15.

3 ve overlapping deletions of the right arm of chromosome 15.

4 the mESO3, psimESO3, was identified on mouse chromosome 15.

5 he Crc gene to a region of 8.8 cM on central chromosome 15.

6 s genetic mapping placed Bcmd near Srebf2 on chromosome 15.

7 lite markers spanning the entire long arm of chromosome 15.

8 orresponding to the syntenic region of human chromosome 15.

9 synteny between mouse chromosome 9 and human chromosome 15.

10 gh-resolution map of the Afr1 locus on mouse chromosome 15.

11 by D15S983 and distally by D15S127 on human chromosome 15.

12 linked to the Trhr and D15Bir7 loci on mouse chromosome 15.

13 approximately 20-centimorgan (cM) region of chromosome 15.

14 lutionary and disease-related instability of chromosome 15.

15 ntaining HuAZ2 at band 22 of the long arm of chromosome 15.

16 in the syntenic 15q15-q21.1 region of human chromosome 15.

17 ique clones representing specific regions of chromosome 15.

18 , has been cloned, sequenced and assigned to chromosome 15.

19 and the corresponding germ-line region from chromosome 15.

20 lusively or preferentially from the maternal chromosome 15.

21 fluorescence in situ hybridization (FISH) to chromosome 15.

22 promyelocytic leukemia (PML) gene located on chromosome 15.

23 (SSLPs); one additional tumor showed LOH on chromosome 15.

24 argazer region has been constructed on mouse Chromosome 15.

25 chromosome 2 in a region syntenic with human chromosome 15.

26 ybridization data that map the mouse gene to chromosome 15.

27 rrangements of the pericentromeric region of chromosome 15.

28 chromosomes, although three of twelve are on chromosome 15.

29 nce of human galactokinase reported to be on chromosome 15.

30 15q11-q13 or paternal uniparental disomy of chromosome 15.

31 required to determine the parental origin of chromosome 15.

32 The mouse gene localized to distal chromosome 15.

33 mon chromosome involved in the ASD group was chromosome 15.

34 eracting protein 1 gene (PSTPIP1) located on chromosome 15.

35 yeloid leukemogenesis and suppressed gain of chromosome 15.

36 ds of cases as a result of trisomy for mouse chromosome 15.

37 al mutant ataxia3 was mapped to distal mouse chromosome 15.

38 slocations that involve NUT, a novel gene on chromosome 15.

39 CYP1A2 are in a head-to-head orientation on chromosome 15.

40 to galactokinase, was subsequently mapped to chromosome 15.

41 21Rk useful as a balancer for proximal mouse chromosome 15.

42 a sixth family member, CELF6, was located on chromosome 15.

43 nd we mapped the mutation in one pedigree to chromosome 15.

44 reen fluorescent protein (eGFP) transgene on chromosome 15.

45 e of a potential tumor suppressor gene(s) on chromosome 15.

46 ch inv dup(15), compared with that on normal chromosomes 15.

47 duplication arose de novo from her father's chromosomes 15.

48 rential association of maternal and paternal chromosomes 15.

49 ), chromosome 11 (8 additional markers), and chromosome 15 (15 additional markers).

50 ved alleles of maternally imprinted genes on chromosome 15 (15q11-13).

51 Linkage maps of rat chromosomes 15, 16, 17, 19, and X were constructed by mu

52 These linkage groups were assigned to rat chromosomes 15, 16, 17, 19, and X, respectively, either

53 for maternal meiosis I (MI) errors involving chromosomes 15, 16, 18 and 21 and increased recombinatio

54 LOH for markers on chromosomes 15, 18, 21, and X was infrequent in leiomyos

55 alterations in the positioning of the human chromosomes 15, 18, X and Y between spermatozoa with the

56 chromosome 7 (80%), chromosome 12 (47%), and chromosome 15 (73%) and partial loss of chromosome 4 (87

57 1 (121 Mb, LOD=5.6) and a suggestive QTL on chromosome 15 (76 Mb, LOD=3.5).

58 of the first carpometacarpal (CMC) joint on chromosome 15 (81 cM; LOD score 6.25).

59 nd 163 Mb, LOD=6.8), and a suggestive QTL on chromosome 15 (96 Mb, LOD=4.7).

60 We identified two DMRs on chromosome 15, a chromosome that was not thought to cont

61 he disease gene within a 17.4 Mb interval on chromosome 15, a region containing 296 genes.

62 fic deficiencies in the percentage of paired chromosome 15 alleles were observed in RTT, AS and autis

63 Replication timing was evaluated for chromosome 15 and 17 loci.

64 gical behavior of this cancer, we mapped the chromosome 15 and 19 translocation breakpoints by fluore

65 used by paternal uniparental disomy (UPD) of chromosome 15 and 2-3% are caused by "imprinting mutatio

66 13 loci in hybrids containing a single human chromosome 15 and at two chromosome 11p15 loci in hybrid

67 rfv3) gene, the rfv3 gene has been mapped to chromosome 15 and confers resistance to MuLV but not to

68 arate chromosomes, with mALT1 gene (gpt1) on chromosome 15 and mALT2 gene (gpt2) on chromosome 8.

69 e Prader-Willi syndrome IC (PWS-IC) on human chromosome 15 and mouse chromosome 7 regulates imprinted

70 and indirect effects of copy number gains in chromosome 15 and provides a framework for the study of

71 RHCG and Rhcg map at 15q25 of human chromosome 15 and the long arm of mouse chromosome 7, re

72 rom the targeted ES cells carry the inverted chromosome 15 and, at the same time, exhibit lighter coa

73 ons such as loss of chromosome 6 and gain of chromosomes 15 and 12p in the former.

74 HM, two significant regions affecting HDL on chromosomes 15 and 16 and one affecting LDL on chromosom

75 bserved at regions orthologous to both human chromosomes 15 and 16 in non-human primates, including O

76 hromosome 1 and other NZO-contributed QTL on chromosomes 15 and 17, as well as with an NON-contribute

77 gene; in 3 cases with morphologically normal chromosomes 15 and 17, RARalpha was inserted into PML on

78 th a reciprocal chromosomal translocation of chromosomes 15 and 17, which results in a fusion protein

79 l/normal state of the sex chromosomes and of chromosomes 15 and 17.

80 itutional Robertsonian translocation between chromosomes 15 and 21, rob(15;21)(q10;q10)c, have approx

81 on and involving loci corresponding to human chromosomes 15 and 21.

82 nt microscopy, the nuclear colocalization of chromosomes 15 and sSMC was analyzed.

83 EJ) contain complicons that coamplify c-myc (chromosome 15) and IgH (chromosome 12) sequences.

84 e 4-like; chromosome 18), Ano6 (anocatmin 6; chromosome 15), and Rnf220 (Ring finger protein 220; chr

85 Zhx2 is located on chromosome 15, and a natural hypomorphic mutation in the

86 lly derived copy of the proximal long arm of chromosome 15, and eat uncontrollably; in Angelman syndr

87 The lbc proto-oncogene maps to chromosome 15, and onco-lbc represents a fusion of the l

88 One found evidence of linkage to markers on chromosome 15, another to markers on chromosome 6, centr

89 This region located on chromosome 15 appears to the major one affecting habitua

90 MPFYVE is also located on chromosome 15, approximately 170 kb telomeric to AF15q14

91 Segmental duplications in chromosome 15 are largely clustered in two regions, on p

92 enotype and maps to the same region of mouse chromosome 15 as the Caracul (Ca) and Reduced coat (Rco)

93 previously characterized and shown to retain chromosome 15 as the only human material.

94 otinic acetylcholine receptor) on a locus of chromosome 15 associated with mental illness, including

95 ssion of ATP10C thus make it a candidate for chromosome 15-associated autism and suggest that it may

96 50), chromosome 13 at 108 cm (LOD=2.10), and chromosome 15 at 108 cM (LOD=2.48).

97 -glyoxylate aminotransferase 2 locus, and on chromosome 15 at the glycine amidinotransferase locus, a

98 mapped to a 6.5-Mb region of the long arm of chromosome 15, at 22.33-24.2 between CYP11A and D15S211.

99 loom syndrome (BLM) has been mapped to human chromosome 15 band q26.1 by homozygosity mapping.

100 ound to reside at chromosome 5, band p21 and chromosome 15, band q26, respectively.

101 he cluster of type II keratin genes on mouse chromosome 15, between the keratin 6 (mK6alpha/mK6beta)

102 In addition, we localized the chromosome 15 breakpoint to a 9-kb region in each of two

103 The causative gene maps to the long arm of chromosome 15 but has not yet been identified.

104 sition, that not only distinguish homologous chromosomes 15 but can be used to follow the transmissio

105 of bands q11.2-q13 of the paternally derived chromosome 15, but it also occurs either because of mate

106 n has been mapped to the distal end of mouse chromosome 15, but the mutated gene has not been found.

107 Murine chromosome 15 carries the sex-affected Pgia8 locus that

108 tumors we observed whole or partial gain of chromosome 15 centering on 15D2-D3 (orthologous to human

109 mosome 15 from a lymphoblastoid cell line, a chromosome 15 centromere-specific DNA probe with a fluor

110 antitative trait locus (QTL) was detected on chromosome 15 (Chr 15) with a highly significant logarit

111 we identified two loci, Pgia8 and Pgia9, on chromosome 15 (chr15) that appear to be implicated in di

112 e Ashkenazi population to a 0.6-Mb region on chromosome 15 containing SCG5 (also known as SGNE1), GRE

113 of eGFP expression, transgene abundance, and chromosome 15 copy number demonstrated that a prepondera

114 EF1B1, is actually a processed pseudogene on chromosome 15 corresponding to an alternative splice for

115 The data offer the first report of a chromosome 15 cosmid library and demonstrate the value o

116 s indicated that MRG15 (MORF-related gene on chromosome 15) could derepress the B-myb promoter by ass

117 ng inverted D segments, DIR family segments, chromosome 15 D segments and multiple D segments were fo

118 f a supernumerary pseudodicentric derivative chromosome 15 [der(15)] that has been called inverted du

119 Supernumerary marker chromosomes (SMCs) of chromosome 15, designated "SMC(15)s," are the most commo

120 as identified for POAG to an 11-cM region on chromosome 15, designated GLC1I.

121 A probe derived from the BCL8 locus on chromosome 15 detected a transcript in human testis and

122 s expressed only from the paternally derived chromosome 15, due to epigenetic imprinting.

123 hildren were identified who had interstitial chromosome 15 duplications and were excluded from furthe

124 Recently, a chromosome 15 duplicon was discovered in the common brea

125 are associated with variants in a region of chromosome 15 encompassing genes encoding the nicotinic

126 tion stage on chromosome 14, and 1 island on chromosome 15 for secondary cell wall deposition, for a

127 In an attempt to isolate human chromosome 15 from a lymphoblastoid cell line, a chromos

128 t increase in homologous pairing specific to chromosome 15 from infant to juvenile brain samples.

129 is identical to a genomic DNA sequence from chromosome 15 (GenBank accession no. AC067805, bp 148976

130 l cloning approach for identifying the BBS4 (chromosome 15) gene, we identified and cloned an unconve

131 osome 12 to sequences downstream of c-myc on chromosome 15, generating dicentric chromosomes and c-my

132 J]F2 mice identified a major locus on distal chromosome 15, given the appellation Carg5, that regulat

133 (5.8%) had hypodiploid karyotypes: 87 had 45 chromosomes, 15 had 33 to 44 chromosomes, none had 29 to

134 y the deletion of small portions of maternal chromosome 15 harboring the UBE3A gene.

135 few cases of paternal uniparental disomy of chromosome 15 have been reported.

136 have identified a conserved region of human chromosome 15 homologous to the mesd, nelg, and hsdr1 fu

137 AC contigs, and FISH of normal or rearranged chromosomes 15 identified duplicated sequences (the END

138 Isodicentric chromosome 15 (Idic15), characterized by duplications of

139 tion rate had also lost at least one copy of chromosome 15 in 70% of the cells.

140 The mouse ACAT-2 gene (Acact2) maps to chromosome 15 in a region containing a quantitative trai

141 ence-tagged site mapping places cPLA2beta on chromosome 15 in a region near a phosphoinositol bisphos

142 chromosome and an autosome corresponding to chromosome 15 in the Bombyx mori reference genome.

143 ti minigene was introduced onto the inverted chromosome 15 in the ES cells by gene targeting.

144 molecules have recently been mapped to human chromosome 15 in the region q22.3-q23 and to the synteni

145 ficant linkage to markers on the long arm of chromosome 15, in a region encompassing RLBP1, the gene

146 TBLV insertions on chromosome 15 (including a newly identified locus, Pad7)

147 lly expressed genes at an imprinted locus on chromosome 15, including the long noncoding RNA IPW.

148 n cell line bearing a partial duplication of chromosome 15 increased the abundance of POLgammaCAT mRN

149 ed a major quantitative trait locus (QTL) on chromosome 15 influencing size variation within a single

150 the breakpoints of inverted duplications of chromosome 15 (inv dup[15]) that include the Prader-Will

151 The genomic locus on chromosome 15 is clonally rearranged in about 4% of DLCL

152 The assignment of the mouse Ku70 gene to chromosome 15 is consistent with the syntenic relationsh

153 As chromosome 15 is one of seven human chromosomes with a h

154 t the sequence reported for galactokinase on chromosome 15 is that of GalNAc kinase, which can phosph

155 unesterified cholesterol levels, whereas the chromosome 15 locus appears to influence both HDL-C conc

156 eterozygotes and C57BL/6J homozygotes at the chromosome 15 locus marker had higher bone mineral densi

157 further refined our signal for insulin 30 on chromosome 15 (LOD 2.38 at 68 cM).

158 rrower diagnosis of persistent stuttering on chromosome 15 (LOD = 1.95 at 23 cM).

159 angrenosum-acne-arthritis to the long arm of chromosome 15 (maximum two-point LOD score, 5.83; recomb

160 The data also indicate that the VH region on chromosome 15 may contain a large duplicated block with

161 form of a supernumerary inverted duplicated chromosome 15, more properly described as an isodicentri

162 The gene on chromosome 15 (MRG15) has high similarity to Drosophila

163 The MORF4-Related Gene on chromosome 15 (MRG15) is a member of a novel family of g

164 No GWS associations were observed at the chromosome 15 nicotinic receptor gene cluster (CHRNA5-CH

165 gene cluster on chromosome 12 of humans and chromosome 15 of mice.

166 Transgenes were integrated on proximal chromosome 15 of the A line and on the Y chromosome of t

167 sed by alterations of the paternally derived chromosome 15 or by maternal uniparental disomy.

168 , more properly described as an isodicentric chromosome 15, or idic(15).

169 In the mouse, Trib is located on chromosome 15, overlapping with and transcribed in the o

170 ation at the novel IL16/STARD5/TMC3 locus on chromosome 15 (P = 5.71 x 10(-7)).

171 ome patients who lack 15q11-q13 deletions or chromosome 15 paternal uniparental disomy.

172 I nondisjunction error involving an altered chromosome 15 produced by both a translocation event bet

173 eport that a new quantitative trait locus on chromosome 15, Rapop5, partly accounts for the murine st

174 ity among SMC(15)s that is not seen in other chromosome 15 rearrangements, such as deletions and dupl

175 tive for SNRPN expression were found to have chromosome 15 rearrangements, while the diagnosis of PWS

176 scent in situ hybridization we mapped Zfr to chromosome 15 region A.

177 non-major histocompatibility complex gene on chromosome 15 regulates long-term survival and is locate

178 icons-a approximately 14-kb primate-specific chromosome 15 repeat that became organized into larger p

179 cripts from the 200-kb human GRINL1A gene on chromosome 15 revealed a complex gene structure comprisi

180 ent 15q13.3 microdeletions, the expansion of chromosome 15 segmental duplications in the human lineag

181 the CYP1A locus, we scanned 75 kilobases of chromosome 15 sequence for high-affinity AhR binding sit

182 ach patient had maternal heterodisomy of the chromosome 15 short arm, whereas PCR of microsatellites

183 A DMR was also identified at the chromosome 15 Slc38a4 gene, which encodes a system A ami

184 We identified a QTL on chromosome 15 that contained Csnk1e (63-86 Mb; Csnk1e=79

185 Our results suggest that an area on chromosome 15 that includes DUOX1, DUOX2, and their matu

186 MFD maps to a narrow interval on bovine chromosome 15 that is syntenic to human chromosome 11p12

187 o loci, one on chromosome 8 and the other on chromosome 15, that influence a component of HDL-C-namel

188 In 10/11 translocations involving chromosome 15, the presence of satellite III DNA was obs

189 B cells not expressing eGFP lost one copy of chromosome 15; the eGFP transgene was lost in these cell

190 the NUT (nuclear protein in testis) gene on chromosome 15 to a few other genes, most frequently the

191 ese results narrow our region of interest on chromosome 15 to an area surrounding the gamma-aminobuty

192 ave analyzed loss of heterozygosity (LOH) on chromosome 15 to ascertain its potential involvement in

193 ts; this translocation fuses the PML gene on chromosome 15 to the retinoic acid receptor alpha (RAR a

194 Here we present a finished sequence of human chromosome 15, together with a high-quality gene catalog

195 lymphomas that displayed a high frequency of chromosome 15 trisomy.

196 imprinted region on the proximal long arm of chromosome 15 underlie a complex neurobehavioral disorde

197 ion studies highlighted a human haplotype on chromosome 15 underlying the risk for tobacco dependence

198 ontent and related traits were mapped to pig chromosome 15 using a three-generation intercross betwee

199 The translocation chromosome 15 was found to be paternal in origin.

200 phenotype correlation, a candidate region on chromosome 15 was identified.

201 ly cryptic event: a 77-kilobase segment from chromosome 15 was inserted en bloc into the second intro

202 al association between maternal and paternal chromosomes 15 was observed in human T lymphocytes by th

203 o GFP-expressing controls, cells with LOH at chromosome 15 were morphologically normal and proliferat

204 etic markers within the 15q11-13 interval on chromosome 15 were used for OSA analysis.

205 en one and four copies of the repeat on each chromosome 15, whereas from eight to 20 copies were foun

206 intervals on human chromosome 12q and mouse chromosome 15, which contain the Aqp5 gene.

207 ephrocerebellar syndrome mapped to 700 kb on chromosome 15, which contained a single novel homozygous

208 ulations analyzed showed a nonrandom gain of chromosome 15, which contains the c-myc gene.

209 Half of the associated SNPs were located on chromosome 15, which corresponds with results that other

210 mmon site of retroviral integration on mouse chromosome 15, which includes the genomic structure of t

211 on of small portions of the maternal copy of chromosome 15, which includes the UBE3A gene.

212 It mapped to chromosome 15, while T-STAR mapped to the syntenic regio

213 ges the promyelocytic leukemia gene (PML) on chromosome 15 with the retinoic acid receptor alpha (RAR

214 han 60%), and partial or complete trisomy of chromosome 15, with copy number increases of the c-myc o

215 The gene is positioned on chromosome 15 within bands q24-25.