ライフサイエンスコーパス: chromosome 6

1 strategy positioned dw on the distal end of chromosome 6.

2 r are frequently observed in the long arm of chromosome 6.

3 fect of susceptibility to HRRD is located on chromosome 6.

4 lity locus was mapped by linkage analysis to chromosome 6.

5 this kallikrein-gene-rich region to porcine chromosome 6.

6 A significant genetic effect was located on chromosome 6.

7 or mouse lung cancer susceptibility locus on chromosome 6.

8 ry region of the mouse Nmp4 gene, located on chromosome 6.

9 antigen, was previously mapped to a locus on chromosome 6.

10 nd maintenance of cells with extra copies of chromosome 6.

11 evidence of a major susceptibility locus on chromosome 6.

12 ated with HLA-B*27:05 and with other SNPs on chromosome 6.

13 major histocompatibility class III region of chromosome 6.

14 f the 'extended MHC class I region' on human chromosome 6.

15 with WM harbour deletions in the long arm of chromosome 6.

16 ains mapping to the q24 band region of human chromosome 6.

17 es, and SM190.2 had an additional segment in chromosome 6.

18 ntly increased the probability of linkage on chromosome 6.

19 these genes, designated APOBEC2, is found on chromosome 6.

20 iasis Susceptibility 1), on the short arm of chromosome 6.

21 r histocompatibility complex (MHC) region on chromosome 6.

22 d and mapped to the syntenic region of mouse chromosome 6.

23 site on the 5G1-ter segment translocated to chromosome 6.

24 has inserted in one or two copies into mouse chromosome 6.

25 of 539 and 553 amino acids and maps to mouse chromosome 6.

26 are located within the HLA class I region of chromosome 6.

27 lacZ reporter locus linked at the same mouse chromosome 6.

28 and one (at -1202 RAGE/+2234 PBX2) to be on chromosome 6.

29 ned odorant receptor gene that maps to mouse chromosome 6.

30 expressed in human tissues and is located on chromosome 6.

31 nt with JME and genotyped markers throughout chromosome 6.

32 from subclones of YACs previously mapped to chromosome 6.

33 cal to that of patients with paternal UPD of chromosome 6.

34 e mouse Lmcd1 locus to the central region of chromosome 6.

35 okine cluster on chromosome 5 and the MHC on chromosome 6.

36 constituted the most common deletions within chromosome 6.

37 evealed maternal uniparental disomy (UPD) of chromosome 6.

38 e detected in other retinal disease genes on chromosome 6.

39 tive trait locus (logarithm of odds = 31) on chromosome 6.

40 ersion of which delayed replication of human chromosome 6.

41 wed frequent loss of heterozygosity (LOH) on chromosome 6.

42 th other mono-allelically expressed genes on chromosome 6.

43 e mutation within an 0.4-Mbp region on mouse chromosome 6.

44 e subtelomeric in location except for one on chromosome 6.

45 hromosome 1 (near the S locus), and ui6.1 on chromosome 6.

46 an extended region covering the MHC locus on chromosome 6.

47 the largest maize Al tolerance QTL found on chromosome 6.

48 d major histocompatibility complex region on chromosome 6.

49 V cannabis dependence, a modest LOD score on chromosome 6 (1.42) near cannabinoid receptor 1 (CNR1) w

50 ence of at least four susceptibility loci on chromosomes 6, 10, 16 and 18, by use of several differen

51 roup 1 had paternal uniparental isodisomy of chromosome 6 (11 cases, including 1 set of identical twi

52 t evidence for linkage in FUSION 1, four (on chromosomes 6, 11, 14, and X) also showed evidence for l

53 We identified multiple suggestive loci on chromosomes 6, 11, and 13 in family DUK6524 and identifi

54 with the human CpG island sequence found on chromosomes 6, 14, and 17.

55 chromosome 12 and three potential regions on chromosomes 6, 15, and 19 that are associated with CAC.

56 NP) map covering almost the entire length of chromosomes 6, 21, and 22.

57 Murine Ian4 maps to chromosome 6, 25 cM from the centromere.

58 p barley genes to the long and short arms of chromosome 6(6H).

59 Allelic deletions on the short arm of chromosome 6 (6p) are one of the common, possibly early,

60 ge cluster of histone genes, HIST1, on human chromosome 6 (6p21-p22) contains 55 histone genes, and H

61 gene for HHC, was mapped on the short arm of chromosome 6 (6p21.3).

62 Group 4 had no identifiable rearrangement of chromosome 6 (7 sporadic cases).

63 Five regions, SLT1 to SLT5, were mapped on chromosomes 6, 7, 8, 19, and X, respectively.

64 or cell lines analyzed), chromosome 2 (53%), chromosome 6 (73%), chromosome 7 (80%), chromosome 12 (4

65 recurrent regions of copy-number decrease on chromosomes 6, 8 and 14 (syntenic with human chromosomes

66 sis mapped loci with lod scores of 5 to 7 on chromosomes 6, 8, and 10 that influence the susceptibili

67 lines, six imprinted pQTL were discovered on chromosomes 6, 9, 10, 11, and 18.

68 with and without aura has been identified on chromosome 6, a locus for migraine without aura to chrom

69 on was explained by a subtelomeric region on chromosome 6; a genome-wide association study showed the

70 ICA69 is encoded by the Ica1 gene on mouse chromosome 6 A1-A2.

71 The sizes of GSD Ia adenomas with chromosome 6 aberrations were larger than the sizes of a

72 On chromosome 6, allele frequency differences localized nea

73 These results strongly suggest that chromosome 6 alterations could be an early event in the

74 e frequencies of BTNL2, a candidate gene for chromosome 6 amplification, in patients with UM.

75 nt genetic alterations, including trisomy of chromosome 6, amplification of N-Myc, modest increases i

76 data suggest that the regions identified on chromosome 6 and 15 contain variants that are possibly a

77 ignificance (MYC/MYCN amplification, CNAs of chromosome 6 and 17), we evaluated clinical, pathologic,

78 The gene spans 236 kilobase pairs on chromosome 6 and consists of 28 exons plus one alternati

79 is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse

80 is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse

81 is located within the 6p21.3 region of human chromosome 6 and contains more than 220 genes of diverse

82 onsiderable interest, we observed trisomy of chromosome 6 and duplication of the mutant met allele in

83 Nap1l5 is located on proximal chromosome 6 and encodes a protein with homology with nu

84 ith a few obvious exceptions such as loss of chromosome 6 and gain of chromosomes 15 and 12p in the f

85 d a single 22.4-Mb region of homozygosity on chromosome 6 and had a homozygous nonsense mutation (c.6

86 o the chemokine receptor CCR6, CCRL1 maps to chromosome 6 and has one intron in the 5' untranslated r

87 The reported association between a locus on chromosome 6 and hip OA could not be confirmed in this p

88 5 patients who showed homozygous regions at chromosome 6 and in 173 unrelated individuals with LCA o

89 ind HLA-B to be the most polymorphic gene on chromosome 6 and in the human genome.

90 Sgce is located at the proximal end of mouse chromosome 6 and is a candidate gene for embryonic letha

91 on, and SNPs near two novel genes: HDGFL1 on chromosome 6 and MAF on chromosome 16.

92 r of highly polymorphic genes found on human chromosome 6 and mouse chromosome 17.

93 th both paternal uniparental disomy (UPD) of chromosome 6 and paternal duplications of the critical r

94 on chromosome 4 and a late-flowering QTL on chromosome 6 and provided evidence for additional sub-QT

95 :pseudogene differences between RAGE/PBX2 on chromosome 6 and PsiPBX2 on chromosome 3, which include

96 The human HMGN3 gene is located on chromosome 6 and spans 32 kilobase pairs, which is nearl

97 ified in control hybrids constructed between chromosome 6 and the BICR6 SCC cell line that is heteroz

98 We mapped the mouse Lbx2 gene to 35 cM on chromosome 6 and the human LBX2 gene to a homologous reg

99 n an intronic SNP in the MMP gene located on chromosome 6 and the regulation of bolting tendency in s

100 BICR6 SCC cell line that is heterozygous for chromosome 6 and which showed no reduction in colony for

101 In addition, evidence for AAO linkage on chromosomes 6 and 10 was identified independently in bot

102 e existence of disease-predisposing genes on chromosomes 6 and 10.

103 The LOD scores for chromosomes 6 and 12 are difficult to interpret, because

104 Chromosomes 6 and 12 have not only main effects but also

105 and a balanced-translocation event involving chromosomes 6 and 13.

106 s by array CGH pointed to regions of loss on chromosomes 6 and 14, where the Rb pathway inhibitor p27

107 1, were identified, whereas multiple SNPs on chromosomes 6 and 16, in addition to SNPs near SFTPD, ha

108 chromosomes 4 and 17, glomerulonephritis to chromosomes 6 and 17, and splenomegaly to chromosomes 1,

109 es 1, 4, and 15 and identified novel loci on chromosomes 6 and 17.

110 In particular, loci on chromosomes 6 and 18 have shown strong and replicable ef

111 ferent approximately 400-kb regions on human chromosomes 6 and 22 and then examined light microscope

112 stantial evidence for susceptibility loci on chromosomes 6 and 7 that appear to influence the factors

113 this study, significant association peaks on chromosomes 6 and 7 were identified through a genomewide

114 single boar family of 72 piglets over swine chromosomes 6 and 8 (SSC6 and SSC8).

115 e BAC/PAC and genetic markers that mapped on chromosomes 6 and 8 of rice.

116 on chromosomes 2 and 5 and heterozygotes on chromosomes 6 and 9, suggested linkage to a small number

117 ing multiple copies of enJSRV are present on chromosomes 6 and 9.

118 nce for additional loci was also observed on chromosomes 6 and X.

119 istone H4 gene on human chromosome 12 (mouse chromosome 6) and the previously described H2a.X gene lo

120 the Iowa isolate, sequencing and analysis of chromosome 6, and approximately 0.9 Mbp of sequence samp

121 n a tight cluster on rat chromosome 4, mouse chromosome 6, and human chromosome 7, is poorly characte

122 (ALP) levels (ALPL on chromosome 1, GPLD1 on chromosome 6, and JMJD1C-REEP3 on chromosome 10).

123 ing on mid-chromosome 2 near 60 cM, proximal chromosome 6, and mid-chromosome 10 were distinct from B

124 contributions (Nba4 on chromosome 5, Lbw4 on chromosome 6, and Nba5 on chromosome 7) and 2 recessive

125 Here we provide evidence that loci on murine chromosome 6, and possibly chromosome 1, are involved in

126 e patient showed homozygosity of SNPs across chromosome 6, and segregation analysis was performed usi

127 ers on chromosome 3, two adjacent markers on chromosome 6, and seven contiguous markers on chromosome

128 Deletions of chromosome 6 are a common abnormality in diverse human m

129 c analysis indicated that, although gains of chromosome 6 are consistently seen in tumors arising on

130 10(-7); and rs13209281 P = 8.3 x 10(-7)) on chromosome 6, around 500 kb upstream of the locus HTR1E

131 s of chromosome 13, which frequently involve chromosome 6 as a partner.

132 r histocompatibility complex (MHC) region of chromosome 6 as an important source of untyped genetic v

133 LD reaches almost twice as far in chromosome 6 as in chromosomes 21 or 22, in agreement wi

134 synchronous replication and autosomal RNA on chromosome 6, ASAR6.

135 .63), chromosome 5 at 139.3 cM (LOD = 0.84), chromosome 6 at 178.9 cM (LOD = 1.91), chromosome 12 at

136 an MCH-2R gene was mapped to the long arm of chromosome 6 at band 6q16.2-16.3, a region reported to b

137 s (LOD) score in the full dataset was 3.3 on chromosome 6 at marker D6S1009; when subjects were limit

138 ocus, as well as a suggestive association on chromosome 6 at the Homo sapiens mediator complex subuni

139 e (STGD3) was further localized to 562 kb on chromosome 6 between D6S460 and a new polymorphic marker

140 nt loci were on chromosome 9 close to ASTN2, chromosome 6 between FILIP1 and SENP6, chromosome 12 clo

141 For one QTL on bovine chromosome 6 (BTA6), previously fine-mapped to a 420-Kb

142 owing the reintroduction of an intact normal chromosome 6 by monochromosome transfer.

143 he TNF p55 receptor (Tnfrsf1a) gene on mouse chromosome 6 (c6), that determines resistance or suscept

144 ne by microarray analysis that is located on chromosome 6 (c6orf32), whose expression is increased du

145 kers on chromosome 15, another to markers on chromosome 6, centromeric to HLA.

146 11756438 = 4.36 x 10(-8)) regions located on chromosomes 6 (CEP85L) and 10 (TAF9BP2).

147 P analysis of known transcribed sequences on chromosome 6 combined with microarray expression analysi

148 d to the 4.5-Mb extended MHC region on human chromosome 6, combining 8 assembled haplotypes, the sequ

149 subcongenic lines from the B6.CAST Ldlr(-/-) chromosome 6 congenic strain (CON6.Ldlr(-/-)) and analyz

150 association with a 200-kb haplotype block on chromosome 6 containing Far2.

151 ng an amplification of the distal portion of chromosome 6 containing ki-ras and loss of heterozygosit

152 ed linkage of idiopathic PD to the region on chromosome 6 containing the Parkin gene (D6S305, logarit

153 active hybridization comparing nonmetastatic chromosome 6-containing (neo6/C8161) versus parental (C8

154 The associated region on chromosome 6 contains the gene for BMP-6, which is expre

155 und to have positive linkage at the q arm of chromosome 6 (D6S441) in 2-point analysis; this was supp

156 We confirmed the high frequency of chromosome 6 deletions in AA and GB, and identified two

157 Sesquiterpene synthase cDNA clones on chromosome 6 do not cross-hybridize on genomic DNA gel b

158 Chromosome 6, either entirely or around the fusion gene

159 Utrophin is a chromosome 6-encoded dystrophin-related protein (DRP), s

160 m randomly chosen clones from four different chromosome 6-enriched plasmid libraries or from subclone

161 These loci reside on chromosome 6 [Estrogen-induced pituitary tumor (Ept)1],

162 r a small distal portion of the short arm of chromosome 6 exhibited a phenotypic syndrome that includ

163 Our study also showed that chromosome 6 exhibited high frequencies of loss of heter

164 study with pigs, a significant segment from chromosome 6 explained 11% of total genetic variance.

165 omosome 6 for Strongyles FEC at 16 weeks and chromosome 6 for body weight at 16 weeks.

166 erent IGEs: a previously identified locus on chromosome 6 for JME (lod score 2.5/4.2), a locus on chr

167 me 14 for Nematodirus average animal effect, chromosome 6 for Strongyles FEC at 16 weeks and chromoso

168 7230, and rs3128965) of HLA-DPB1 and DPB2 on chromosome 6 formed a distinctive peak with log P values

169 e, constructed by placing the Pas1 region of chromosome 6 from A/J mice onto the genetic background o

170 ied a major susceptibility locus (HIVAN4) on chromosome 6 G3-F3, with BALB alleles conferring a twofo

171 In addition, Cyclin D2, a chromosome 6 gene, was amplified in a subset of tumors.

172 The chromosome 6 gene, which we call Artles (for arterial le

173 sion was resected and found to have lost the chromosome 6 haplotype encoding the HLA-C*08:02 class I

174 tify 19 differentially methylated regions on chromosome 6 harboring MHC gene clusters.

175 Chromosome 6 harbours the largest transfer RNA gene clus

176 Loss of genetic material on chromosome 6 has been associated with progression of hum

177 The most promising QTL on mouse chromosome 6 has provided clues for unraveling the molec

178 PCR karyotyping that refined the region on chromosome 6 identified CRSP3/DRIP130, a transcriptional

179 train with TALLYHO/Jng (TH) donor segment on chromosome 6 in a C57BL/6 (B6) background that harbors a

180 ated Rsvs1, was identified on proximal mouse chromosome 6 in both recombinant populations.

181 in both, this region maps to homeologues of chromosome 6 in diploid congeners, but is located at opp

182 ng to chromosome 7q21 in humans and proximal chromosome 6 in mice was redefined.

183 chromosome 12p13 of the human genome, and on chromosome 6 in mouse.

184 Thus, we implicated a specific gene on chromosome 6 in the etiology of melanoma metastasis and

185 (-8)]) achieving genome-wide significance on chromosome 6 in the HLA class II region.

186 r linkage to 5 distinct chromosomal regions: chromosome 6 in the parkin gene (MLOD = 5.07; LOD = 5.47

187 gene contains five exons and is localized to chromosome 6 in the region corresponding to band 6 D1-D2

188 cing pulmonary function on the q-terminus of chromosome 6 in the region of 184 cM (D6S503) to 190 cM

189 MP1/Fc mice by inheritance of AKR alleles on chromosome 6 in the region of Pparg .

190 This gene is positioned on chromosome 6 in the vicinity of the IFNGR1 gene in a hea

191 hasing HLA-A, HLA-B, and HLA-DRB1 alleles on chromosome 6 in unrelated individuals.

192 arcanum accession LA2157 to the short arm of chromosome 6, in a genetic interval as Mi-1 and the Clad

193 ences mapped to an imprinted gene cluster on chromosome 6, including Dlx5 and Dlx6, whose transcripti

194 We showed previously that introducing chromosome 6 into metastatic human melanoma cell lines s

195 sis revealed a recurrent clonal inversion of chromosome 6, inv(6), in thymic lymphomas from multiple

196 Chromosome 6 is a metacentric chromosome that constitute

197 he major histocompatibility complex (MHC) on chromosome 6 is associated with susceptibility to more c

198 son helper integration site-1 (AHI1) gene on chromosome 6 is associated with susceptibility to schizo

199 Though deletion of the long arm of chromosome 6 is one of the most common aberrations in tu

200 The HLA gene complex on human chromosome 6 is one of the most polymorphic regions in t

201 Recent work has suggested that HLA-Cw6 on chromosome 6 is the risk variant in the PSORS1 [MIM 1779

202 adenoma susceptibility 1 (Pas1), located on chromosome 6, is the major locus affecting inherited pre

203 The chromosome 6 linkage region contains 73 genes; several l

204 Genetic mapping revealed that a locus on chromosome 6 linked to IgG subclass levels that affected

205 ed individuals from 3 families affected with chromosome 6-linked NCMD (MCDR1) and 2 individuals affec

206 A chromosome 6 locus (7,370,061-7,606,946) was sequenced i

207 conclude that the relation between the mouse chromosome 6 locus and atherosclerosis is complex and is

208 We identified 23 sequence variants in the chromosome 6 locus associated with IPF.

209 e in leukotriene synthesis and was among the chromosome 6 locus candidate genes that we examined.

210 heterozygotes and CASA/Rk homozygotes at the chromosome 6 locus marker had higher body fat percentage

211 The chromosome 6 locus overlaps one for muscular VSD suscept

212 cularly vitiligo, in this family, and that a chromosome 6 locus, most likely AITD1, may mediate the o

213 now report detailed genetic analysis of the chromosome 6 locus.

214 suggestive linkage for diabetes mellitus on chromosome 6 (lod score 2.96), for hypertension on chrom

215 arithm of odds [LOD] score = 1.9) and PBF on chromosome 6 (LOD score = 2.7).

216 of sharing of maternally derived alleles on chromosome 6 (LOD(MO) = 3.0).

217 An additional region containing a QTL on chromosome 6, LOD = 4.6, showed linkage in female mice o

218 FEV1 was most influenced by the locus on chromosome 6 (logarithm of the odds favoring genetic lin

219 e strongest FUSION 2 linkage results were on chromosomes 6 (maximum logarithm of odds score [MLS] = 2

220 ipts was proposed to destabilize the cognate chromosome 6 Mkrn1 source gene mRNA, with a partial redu

221 M), chromosome 14 (MLS = 2.74 at 58 cM), and chromosome 6 (MLS = 2.66 at 96 cM).

222 Complex CNA were observed involving chromosomes 6 (n=2), 15 (n=2) and 21 (n=11) with multipl

223 separated by three introns and maps to mouse chromosome 6 near D6mit25.

224 ce for linkage of factor 1 to two regions on chromosome 6 near markers D6S403 (logarithm of odds [LOD

225 s with TNDM, in whom neither paternal UPD of chromosome 6 nor duplication of 6q24 have been found, sh

226 We have made a high-resolution HAPPY map of chromosome 6 of Dictyostelium discoideum consisting of 3

227 ial chromosome (BAC) clones on the pachytene chromosome 6 of potato.

228 nic background in which the antigen locus on chromosome 6 of the NOD mouse is replaced by a segment f

229 corresponding to the MDH gene, identified on chromosome 6 of the Plasmodium falciparum genome, was am

230 een identified as an EDS1 homolog present on chromosome 6 of tomato.

231 The pachytene chromosomes 6 of potato and tomato (S. lycopersicum) sha

232 1.37 (95% CI = 1.19-1.58), P = 3 x 10(-13)), chromosome 6 (OR = 1.50 (95% CI = 1.28-1.75), P = 10(-13

233 overall association was found for SNP183 on chromosome 6 (p-value = 1.246 10(-13)).

234 loci as potential linkage regions for IOP on chromosomes 6 (P = 0.008) and 13 (P = 0.0007).

235 cting replication-dependent histone genes on chromosome 6, potentially representing the chromatin arc

236 Comparative mapping of the chromosome 6 QTLs identified Chrm2 (cholinergic receptor

237 n, designated CON6, containing the resistant chromosome 6 region derived from the CAST/Ei strain (CAS

238 Chromosome 6, region p25, gains correlated with good sur

239 At the HLA locus on chromosome 6, results suggest the existence of multiple,

240 t sequencing of all retinal disease genes on chromosome 6 revealed a novel pathogenic TULP1 mutation

241 g of several potato BACs on tomato pachytene chromosome 6 revealed an overall colinearity between the

242 women and report an association in LIN28B on chromosome 6 (rs314276, minor allele frequency (MAF) = 0

243 fied a novel fIIP locus in the HLA region of chromosome 6 (rs7887 P meta = 3.7 x 10(-09)).

244 10(-8)): a novel locus near SGK1/SLC2A12 on chromosome 6 (rs9321453, P= 1.0 x 10(-9)), and two loci

245 constructing a congenic strain in which the chromosome 6 segment from CAST/Ei was transferred to a C

246 The chromosome 6 segment was also transferred onto the backg

247 hromosome) that cover 98.3% of the published chromosome 6 sequences.

248 iensis implied that the nontelomeric copy on chromosome 6 served as a template for subsequent amplifi

249 didate genes in an 11.9-Mb linkage region on chromosome 6 shared by 2 multiplex families identified 2

250 somatic mosaicism for uniparental disomy of chromosome 6 should also be considered in patients with

251 Replication of the chromosome 6 SNP, rs4272729, in an additional 745 person

252 We show here that human chromosome 6 specifically reduces the proliferation or v

253 n the Wingless (WNT) pathway and deletion of chromosome 6 (subgroup B) and mutations in the Sonic Hed

254 eported here prompt us to speculate that the chromosome 6 susceptibility may be coded for by cis-acti

255 nits, and Atp6v1b1 maps to a region of mouse chromosome 6 syntenic to human 2p13, the location of ATP

256 A physical map of nearly 1 Mb containing the chromosome 6 telomere was constructed, and polymorphic m

257 The chromosome 6 telomeric region provided significant evide

258 an interaction between Mcs8 and a region on chromosome 6 termed Mcsm1 (modifier of Mcs), which had n

259 HLA) complex is a series of genes located on chromosome 6 that are important in normal immune functio

260 orted the identification of a locus on mouse chromosome 6 that confers almost total resistance to ath

261 m in an intronic region of the BTBD9 gene on chromosome 6 that confers substantial risk for RLS.

262 a locus for aortic lesion formation on mouse chromosome 6 that exhibits a highly significant lod scor

263 eous quantitative trait loci (QTLs) on mouse chromosome 6 that have unexpectedly large phenotypic eff

264 We also identified a modifier locus on chromosome 6 that interacts with the loci on chromosome

265 We identify a deletion on chromosome 6 that removes approximately 150 kb in the cd

266 or (TNF) loci (termed haplotype LTA-TNF2) on chromosome 6 that shows differential association with rh

267 rain carried a large deletion in one copy of chromosome 6 (the shortest homologue, or Chr6b).

268 Separated by approximately 10 kb on chromosome 6, the coding sequences of RNases A-1 and A-2

269 s at rs17301249, mapping to the EYA4 gene on chromosome 6: the minor allele conferred improved respon

270 n chromosome 2 were 2.79, 0.20, and 3.26; on chromosome 6, they were 3.39, 0.00, and 0.92; and on chr

271 Interestingly, p220 foci associate with chromosome 6 throughout the cell cycle and with chromoso

272 The data show that the chromosome 6 tile path array is useful in mapping copy n

273 entify candidate TSGs, we have constructed a chromosome 6 tile path microarray.

274 human cancers including prostate cancer, and chromosome 6 transferred into cancer cells induces senes

275 Maternal UPD of chromosome 6 unmasked a mutation in the TULP1 gene as a

276 Cf-2 and Mi-1 homologs were mapped on chromosome 6 using a subset of the F2.

277 The frequency of losing a region of chromosome 6 varied according to the age when tumorigene

278 allele was a universal event, and trisomy of chromosome 6 was again frequent.

279 A significant QTL on chromosome 6 was associated with severe kidney infection

280 Aneuploidy of chromosome 6 was independent of activating mutations in

281 ge when tumorigenesis was initiated; loss of chromosome 6 was significantly higher when oncogene expr

282 a dense cluster of genes on the short arm of chromosome 6, was first noted over 30 years ago.

283 an leukocyte antigen (HLA) class II genes on chromosome 6, we postulated that a linkage disequilibriu

284 Using the manual annotation of human chromosome 6, we show that both these methods result in

285 All genes on chromosome 6 were then tested in the gene-level linkage

286 rkers RM19291 and RM8072 on the short arm of chromosome 6, where a gene for resistance to BPH was map

287 A minor QTL (QTL_6_1) was also detected on chromosome 6, where no gene for soybean aphid resistance

288 haplotype for multiple sclerosis (at HLA on chromosome 6), which explains only a fraction of the inc

289 he major histocompatibility complex locus on chromosome 6, which contains a multitude of overlapping

290 a E6 requires copy number increases of mouse chromosome 6, which is partially orthologous to human ch

291 e gene HLA-DQA1 located in the MHC region on chromosome 6, which was reported in previous studies usi

292 We previously mapped a locus on chromosome 6 with a large effect (LOD > 6) on aortic les

293 nd 2.4x10(-10), respectively; NTAN1), and on chromosome 6 with adrenic acid after adjustment for arac

294 Here, we compare manual annotation of human chromosome 6 with annotation performed by EAnnot in orde

295 2.2; chromosome 2, with a LOD score of 2.1; chromosome 6, with a LOD score of 4.2; and chromosome 12

296 analysis of these families revealed a common chromosome 6, with a novel 40 bp exon 3 deletion that co

297 Evidence of linkage was obtained on chromosome 6, with a peak 2-point logarithm of the odds

298 K as a long sought-after oncogene mapping at chromosome 6, with novel functions in melanoma prolifera

299 nificantly associated with the HLA region on chromosome 6, with odds ratios (ORs) of 3.24 (95% CI 2.3

300 (SNPs) mapping to the class II MHC region on chromosome 6, with rs9277378 (located in HLA-DPB1) havin