ライフサイエンスコーパス: chromosome congression

1 nment of chromosomes at the metaphase plate (chromosome congression).

2 etochore Mad2 became undetectable soon after chromosome congression.

3 mosome oscillation, but is not essential for chromosome congression.

4 romosomes towards the metaphase plate during chromosome congression.

5 P-E farnesylation are required for efficient chromosome congression.

6 mitotic spindle equator, a process known as chromosome congression.

7 aration in early mitosis promoting efficient chromosome congression.

8 nesins that may be important for its role in chromosome congression.

9 with pharmacological agents and for mitotic chromosome congression.

10 uding kinetochore-microtubule attachment and chromosome congression.

11 ed defects in spindle assembly and metaphase chromosome congression.

12 eparation in prophase facilitates subsequent chromosome congression.

13 taneously promoting checkpoint signaling and chromosome congression.

14 d assembly is spatially regulated to achieve chromosome congression.

15 otor EG5 for proper spindle architecture and chromosome congression.

16 ple and stable self-organizing mechanism for chromosome congression.

17 e separation, spindle pole organization, and chromosome congression.

18 tension-responsive signal transduction, and chromosome congression.

19 ulator of Plk1 at the kinetochore to promote chromosome congression.

20 localization at the kinetochore and rescued chromosome congression.

21 protein E may contribute to Xorbit's role in chromosome congression.

22 ntial for checkpoint control and for correct chromosome congression.

23 ession in the cell, and correlates with slow chromosome congression.

24 robust bipolar spindle capable of efficient chromosome congression.

25 K led to reduced centromere stretch, delayed chromosome congression, alignment defects, and severe mi

26 he mitotic spindle is required for efficient chromosome congression and accurate chromosome segregati

27 This was accompanied by defects in chromosome congression and alignment of the maternal and

28 ein (HURP) as a protein that is required for chromosome congression and alignment.

29 r of the kinesin-10 family) are required for chromosome congression and alignment; Kif4A and Kif4B (m

30 erotelic attachment, resulting in failure of chromosome congression and an increased propensity for l

31 thout functional centrosomes have a delay in chromosome congression and anaphase onset, which can be

32 xchange factors implicating small GTPases in chromosome congression and cytokinesis.

33 e function of two sister kinetochores during chromosome congression and imply that vertebrate kinetoc

34 assembly of the bipolar spindle and promotes chromosome congression and interkinetochore tension duri

35 hrough mitosis during metaphase, even though chromosome congression and metaphase alignment do not ap

36 the first zygotic division, PLK-1-dependent chromosome congression and metaphase plate alignment are

37 as a crucial component that monitors proper chromosome congression and mitotic timing during cell di

38 ith abnormally condensed chromosomes, failed chromosome congression and multiple centrosomes.

39 Subtle losses in Plk1 activity impaired chromosome congression and produced severe anaphase dysf

40 ent motor activity of CENP-E serves to power chromosome congression and provides a flexible, motile t

41 Genome stability relies upon efficacious chromosome congression and regulation by the spindle ass

42 In the absence of Nup358, chromosome congression and segregation are severely pert

43 Chromosome congression and segregation have been widely

44 newly developed system for observing meiotic chromosome congression and segregation in living maize c

45 amplification and is required for efficient chromosome congression and segregation in mammalian cell

46 rnover of the spindle is a driving force for chromosome congression and segregation in mitosis.

47 Coordination of cytokinesis with chromosome congression and segregation is critical for p

48 Chromosome congression and segregation require the prope

49 dynamic spindle microtubules and drives both chromosome congression and segregation.

50 her effectors to coordinate cytokinesis with chromosome congression and segregation.

51 ins CENP-E and CENP-F, which are involved in chromosome congression and spindle assembly checkpoint s

52 -1 down-regulation significantly compromises chromosome congression and the deposition of HJURP-CENP-

53 g regulation of microtubule dynamics, proper chromosome congression, and correction of improper kinet

54 abnormal chromosome arm orientation, delayed chromosome congression, and sensitized cells to nocodazo

55 has conserved roles in kinetochore assembly, chromosome congression, and spindle checkpoint signaling

56 the conserved NDC80 complex are required for chromosome congression, and their disruption results in

57 t early prometaphase, started to fade during chromosome congression, and then disappeared at midanaph

58 g microtubule dynamics, spindle assembly and chromosome congression, and thus cell cycle progression

59 nstrating that spindle length regulation and chromosome congression are intrinsic to the spindle and

60 is a kinesin-like motor protein required for chromosome congression at prometaphase.

61 s at kinetochores and resulted in defects in chromosome congression at the metaphase plate.

62 After stable attachment, throughout chromosome congression, at metaphase, and throughout ana

63 e interactions with microtubules, and direct chromosome congression, biorientation, error correction,

64 the spindle assembly checkpoint (SAC) and in chromosome congression, but the role of its catalytic ac

65 Kinetochores mediate chromosome congression by either sliding along the latti

66 Perturbing chromosome congression by other means also resulted in f

67 ccharomyces cerevisiae) was shown to mediate chromosome congression by promoting catastrophe of long

68 ing motor proteins, Cin8p and Kip1p, mediate chromosome congression by suppressing kMT plus-end assem

69 ochore associations, however, this effect on chromosome congression could be phenocopied.

70 p-T78-dependent Plk1 localization induced a chromosome congression defect and compromised the spindl

71 gical defects, disoriented mitotic spindles, chromosome congression defects and delayed mitotic progr

72 T-based Aurora B kinase activity, and lethal chromosome congression defects in cancer cells.

73 er KT components, impaired KT-MT attachment, chromosome congression defects, and whole-chromosome ins

74 vents binding of Class I proteins and causes chromosome congression defects, but does not perturb spi

75 Loss of Shot also leads to chromosome congression defects, cell cycle progression d

76 RH leads to loss of CENP-E and consequently, chromosome congression defects.

77 th multiple disorganized spindles and severe chromosome congression defects.

78 Net1 is required for chromosome congression during metaphase and generation o

79 -related protein that has been implicated in chromosome congression during mitosis, and we found that

80 provide the polar ejection force needed for chromosome congression during mitosis.

81 rotubule motor protein that is essential for chromosome congression during mitosis.

82 creased centrosome separation but also their chromosome congression errors and mitotic delay.

83 y through prometaphase and display increased chromosome congression errors.

84 Strong mitotic arrest and chromosome congression failure occurred after Pp1-87B do

85 results in perturbing spindle formation and chromosome congression following maturation.

86 -E motor activity as an essential feature of chromosome congression from poles and localized PP1 deli

87 functions required to establish and maintain chromosome congression have distinguishable requirements

88 Chromosome congression in cells also requires positive c

89 has evolved to facilitate Bub3 activity and chromosome congression in higher eukaryotes.

90 dly growing cell lines and were required for chromosome congression in mitotic HeLa cells, the gradie

91 stem also affects spindle pole formation and chromosome congression in vivo.

92 the DYNLT3 light chain, may be important for chromosome congression, in addition to having a role in

93 tor to anaphase A but is not responsible for chromosome congression, interkinetochore tension, or the

94 sion on the kinetochore, and in its absence, chromosome congression is defective.

95 Thus, CENP-E-driven chromosome congression is guided by microtubule detyrosi

96 nally, KLP61F activity contributes to normal chromosome congression, kinetochore spacing, and anaphas

97 chromosome passenger complex (CPC) controls chromosome congression, kinetochore-microtubule attachme

98 emature exit from mitosis without detectable chromosome congression or anaphase movements.

99 in spindle pole organization and separation, chromosome congression or segregation, and anaphase spin

100 I was recently revised by the discovery that chromosome congression precedes metaphase I arrest.

101 mprove our understanding of how prometaphase chromosome congression relates to anaphase chromosome se

102 Chromosome congression requires the stable attachment of

103 the kinetochore is critical for facilitating chromosome congression, segregation, and checkpoint sign

104 ), with a concomitant increase in defects in chromosome congression, separation, and segregation.

105 O-specific isopeptidases, causes a defect in chromosome congression that depends on its precise kinet

106 zed between homologous chromosomes, promotes chromosome congression through the action of the chromok

107 ation of the centrosome/nucleus complex, for chromosome congression to a well ordered metaphase plate

108 fission yeast kinesin-8 contributes both to chromosome congression to the metaphase plate and to the

109 4 into mammalian cells at prophase inhibited chromosome congression to the metaphase plate with many

110 kinetochore capture at prometaphase, timely chromosome congression to the metaphase plate, and prope

111 ryonic fibroblasts (MEFs) display defects in chromosome congression to the metaphase plate, severe ch

112 Dynein/dynactin inhibition did not block chromosome congression to the spindle equator in prometa

113 attachments in Nnf1R-depleted cells prevent chromosome congression, whereas those in Mcm21R-depleted