ライフサイエンスコーパス: chromosome number

1 close relatives changing in genome size and chromosome number.

2 species by hybridization without a change in chromosome number.

3 inkage groups, which agrees with the haploid chromosome number.

4 hromosomal rearrangements and alterations in chromosome number.

5 esting aberrant cell division, and increased chromosome number.

6 displayed significantly fewer alterations of chromosome number.

7 he tumour cell and was not simply related to chromosome number.

8 s of the two mitochondrial rRNA genes and in chromosome number.

9 idizations that could account for their high chromosome number.

10 resulting in gametes containing the correct chromosome number.

11 ic accumulation of cells with a hypotriploid chromosome number.

12 erile, producing aneuploid eggs with altered chromosome number.

13 age-stage human embryos carrying an abnormal chromosome number.

14 s, allowing evolution of chromosome size and chromosome number.

15 ouse strain(s), class of polymorphism(s) and chromosome number.

16 ctivated and exhibit a broad distribution of chromosome numbers.

17 id, in that they harbour cells with abnormal chromosome numbers.

18 ing that these neoplasms have instability of chromosome numbers.

19 latter two taxa have significantly different chromosome numbers.

20 ated through subsequent generations with new chromosome numbers.

21 process generates cells that carry abnormal chromosome numbers.

22 in microtubule-kinetochore interactions and chromosome numbers.

23 ra-CTP compared with cell lines with diploid chromosome numbers (66.5 v 13.6 pmol/mg protein and 137.

24 An abnormal chromosome number, a condition known as aneuploidy, is a

25 Genome size was correlated with chromosome number across all ferns despite some substant

26 omes 1, 2, 3, (6), 11, (13), 16, 20, and 21 (chromosome number alterations are indicated in parenthes

27 No polymorphism in DNA sequence or chromosome number among individuals collected within a l

28 generations, despite the fact that the mean chromosome number among lines was approximately 38.

29 an 70% of the tumor cells containing altered chromosome number and a mean chromosome number of 56.

30 ints are essential for preserving the normal chromosome number and act synergistically with homologou

31 hat contain multiples of the typical diploid chromosome number and are found in many different organi

32 planation for the prevalence of hyperdiploid chromosome number and centrosome amplification observed

33 Incorrect chromosome number and chromosomal instability are hallma

34 asps exhibited chromosomal clines, involving chromosome number and decreasing of GC content, latitudi

35 ould result in aneuploidy (state of abnormal chromosome number and DNA content) at the next mitosis s

36 Reduction in chromosome number and genetic recombination during meios

37 s mitotic spindle orientation and integrity, chromosome number and genomic stability.

38 m healthy human liver samples and determined chromosome number and identity using traditional karyoty

39 Karyotype analysis showed that increased chromosome number and multiple Robertsonian translocatio

40 ese divisions typically result in defects in chromosome number and stability.

41 N) results in an increased rate of change of chromosome number and structure and generates intratumou

42 Changes in chromosome number and structure are important contributo

43 are the events that initiate the changes in chromosome number and structure between species, and lik

44 isms actively maintain the stability of both chromosome number and structure.

45 yos displayed a higher incidence of aberrant chromosome numbers and mitotic dysfunction compared to w

46 Chromosome numbers and molecular markers (AFLPs) documen

47 infer ancestral character reconstructions of chromosome numbers and nuclear DNA contents.

48 ions in the tetrapod lineage may account for chromosome numbers and provides histories for several hu

49 Although unstable chromosome numbers and recurrent aneuploidies drive a la

50 , genic incompatibilities and differences in chromosome numbers and structure within hybrid genomes a

51 ere already characterized by possessing high chromosome numbers and that the earliest divergences in

52 10; n, gametic chromosome number; x, haploid chromosome number) and Cardaminopsis arenosa (2n = 4x =

53 led directly with cell size (and so with the chromosome number), and bands often contained clusters o

54 events that fundamentally alter DNA content, chromosome number, and gene dosage.

55 genized, undergo grafts, tolerate changes in chromosome number, and provide fertile offspring after w

56 icial genes that are activated by changes in chromosome number, and that this elaborate mechanism reg

57 utant p53 demonstrated the same stability of chromosome number, and the same stability of chromosome

58 gin of modern ferns from ancestors with high chromosome numbers, and the occurrence of several whole-

59 is characterized by widespread imbalances in chromosome number (aneuploidy) and loss of heterozygosit

60 In other tumours, an abnormal chromosome number (aneuploidy) has suggested an instabil

61 mal instability (CIN) leading to an abnormal chromosome number (aneuploidy) is observed.

62 BRCA2-deficient cells exhibit alterations in chromosome number (aneuploidy), as well as structurally

63 Segregation errors lead to an abnormal chromosome number (aneuploidy), which typically results

64 ture, as manifested by tolerance to changing chromosome numbers (aneuploidy and polyploidy), genome s

65 of chromosome evolution and step changes in chromosome number applicable to a wide range of organism

66 rsity in genome size, replicon geometry, and chromosome number are discussed at inter- and intraspeci

67 Abnormalities of chromosome number are the most common genetic aberration

68 Unreduced gametes (gametes with the somatic chromosome number) are known to facilitate polyploid for

69 Strain GR131 has wild-type morphology and chromosome number, as assessed by flow cytometry.

70 Dosage balance requirements maintained chromosome numbers at or near the tetraploid level, and

71 t aneuploidy can perpetually destabilize the chromosome number because it unbalances the elements of

72 ation (XCI) compensates for differences in X-chromosome number between male and female mammals.

73 angements that may underlie the variation in chromosome number between these species.

74 rant karyotypes with alterations not only of chromosome number but also of chromosome structure inclu

75 suggest that STAG2 has a role in controlling chromosome number but not the proliferation of bladder c

76 nts, polyploidy and subsequent reductions in chromosome number by fusion are major sources of chromos

77 ms that reproduce sexually must reduce their chromosome number by half during meiosis to generate hap

78 lled X signal elements (XSEs) communicates X chromosome number by repressing the activity of the mast

79 ecially monophyletic taxa with multiple base chromosome numbers, can result from clade-specific genom

80 n are the most common engines of the runaway chromosome number change observed.

81 the main evolutionary mechanisms generating chromosome number change.

82 We found that the chromosome-number changes persisted, and TERT-positive A

83 f transformed colonies were heterogeneous in chromosome number, consistent with the hypothesis that a

84 rom DMP1-null animals revealed pseudodiploid chromosome numbers, consistent with the retention of wil

85 d breaks are elevated 3- to 12-fold, but the chromosome number distribution remains unchanged.

86 utterflies that rapidly evolved the greatest chromosome number diversity known in animal kingdom with

87 This indicates that chromosome numbers evolve via random walk along branches

88 Plasticity in chromosome number following targeting has been proposed

89 The diploid chromosome number for 52 male C. punctulatus sampled fro

90 The reduction of the basic chromosome number from 12 to 10 in chloridoids and panic

91 The reduction of the basic chromosome number from 12 to 7 in the Triticeae has take

92 Controversies concerning the reduction of chromosome number from 48 to 46 in humans by putative fu

93 oid numbers of chromosomes, and they vary in chromosome number from cell to cell within a single tumo

94 We report BMD cardiomyocytes with a normal chromosome number, fusion of BMD cells with host cardiom

95 nd separated (S-type) 5S and 35S rDNA units, chromosome number, genome size and ploidy level.

96 High hyperdiploidy (a modal chromosome number >50) and an age of 1 to 5 years were a

97 Aneuploidy, an aberrant chromosome number, has been recognized as a common chara

98 Aneuploidy, an abnormal chromosome number, has been recognized as a hallmark of

99 Changes in chromosome number have a critical role in the evolution

100 ated duplication/triplication(s), angiosperm chromosome numbers have usually been restored to a narro

101 Because of their high chromosome numbers, homosporous vascular plants were con

102 Changes in chromosome number impair fitness by disrupting the balan

103 mosome structure among percomorphs show that chromosome number in a pipefish ancestor became reduced

104 -chromosome instability leading to incorrect chromosome number in dividing cells-can arise from defec

105 We find that length correlates with chromosome number in the mother cell.

106 sults reveal Mps1 as a critical regulator of chromosome number in zebrafish, and demonstrate how slig

107 this study, we analyse genome size data and chromosome numbers in a phylogenetic framework to explor

108 general mechanism of restoring small linear chromosome numbers in higher eukaryotes.

109 in Trp53(515C/515C) mice retained a diploid chromosome number, in sharp contrast to aneuploidy obser

110 particular produce offspring with different chromosome numbers, including diploid and tetraploid pro

111 major sources of chromosomal evolution, but chromosome number increase by fission has been relativel

112 y was largely lacking until mouse models for chromosome number instability were used.

113 Patients were stratified by modal chromosome number into 4 groups: 24 to 29 (N = 46); 33 t

114 rlier hypothesis that changes in C. albicans chromosome number is a common means to control a resourc

115 mes remains highly conserved in evolution as chromosome number is constant and comparative chromosome

116 The resulting reduction in chromosome number is essential to prevent the generation

117 X chromosome number is relayed by X signal elements (XSEs)

118 Aneuploidy, an incorrect chromosome number, is a hallmark of cancer.

119 rom aneuploidy, which is a state of abnormal chromosome number, is crucial to understanding their res

120 ich is hybrid speciation without a change in chromosome number, is facilitated by adaptation to a nov

121 e name(s), functional description, organism, chromosome number, location, Entrez Gene ID, GO terms, I

122 la has a short life cycle and relatively low chromosome number, making it a potential model plant for

123 y distinct cells that differ with respect to chromosome number manifested as aneuploidy; however, the

124 senting cellular doubling time, DNA content, chromosome number, metacentric chromosome frequency, tel

125 Rev3L null cells had increased chromosome numbers, most commonly near pentaploid, and d

126 exhibiting aneuploidy still had the expected chromosome number, mostly through reciprocal monosomy-tr

127 ber of linkage groups and the actual haploid chromosome number (N = 31).

128 However, the reduced genome size and chromosome number (n = 5) of Arabidopsis complicates com

129 This reduction in chromosome number, not observed in p53-null cells with M

130 sage compensation states are determined by X chromosome number, not phenotypic sex.

131 This reduction in chromosome number occurs through two highly asymmetric c

132 hoblastic leukemia (ALL), defined by a modal chromosome number of 51 to 65, we assessed the growth po

133 ch cells exhibited 40% aneuploidy and a mean chromosome number of 54.

134 taining altered chromosome number and a mean chromosome number of 56.

135 A chromosome number of four was confirmed by cytological k

136 Karpechenko [15] first reported the accurate chromosome number of oilseed rape (Brassica napus L., 2n

137 e or more markers, agreeing with the haploid chromosome number of tea.

138 Meiosis divides the chromosome number of the cell in half by having two roun

139 amilies Solanaceae and Rubiaceae had a basic chromosome number of x=11 or 12.2) No whole-genome dupli

140 thologous markers in one genome and only the chromosome number on which each marker resides in the ot

141 the database using a specified gene symbol, chromosome number or tumor model to identify both CIS ge

142 ccepted mechanism for generating an aberrant chromosome number, or aneuploidy, is through nondisjunct

143 Most errors in chromosome number originate from the egg, and maternal a

144 Here we tested if multiple base chromosome numbers originated due to genome diploidizati

145 ons, which reduced initiation efficiency and chromosome number per cell, and the degree of suppressio

146 We found that chromosome numbers possess a strong phylogenetic signal.

147 mic features as broad ploidy variation, high chromosome numbers, presence of numerous microchromosome

148 nome-another phaseoloid legume with the same chromosome number-provide provisional genetic locations

149 In the eastern samples, the diploid chromosome number ranged from 37 to 45, whereas in Orego

150 al angiosperms affected by WGD, we show that chromosome number reduction (CNR) is best explained by i

151 ed by considerable karyotype reshuffling and chromosome number reduction and a neopolyploidy event du

152 chromosomal rearrangements that led to maize chromosome number reduction from 20 to 10 were uncovered

153 ppears to be the dominant mechanism of basic chromosome number reduction in grasses.

154 to be important mechanisms underlying grass chromosome number reduction.

155 Homosporous ferns have extremely high chromosome numbers relative to flowering plants, but the

156 The chromosome numbering schemes of the genetic linkage and

157 ring plants, but the species with the lowest chromosome numbers show gene expression patterns typical

158 Quantification of chromosome numbers showed that Klf4(-/-) MEFs were aneup

159 and that dosage balance mechanisms enforced chromosome number stability.

160 chromosomal repatterning, including altered chromosome numbers, structure and distribution of repeat

161 Aneuploidy, an abnormal chromosome number that deviates from a multiple of the h

162 Most solid tumors are aneuploid, having a chromosome number that is not a multiple of the haploid

163 A change in chromosome number that is not the exact multiple of the

164 t in sexual reproduction is the reduction in chromosome number that occurs at the meiosis I division.

165 While changes in chromosome number that result in aneuploidy are associat

166 ing cell-cycle entry and controlling ploidy (chromosome number), the effector molecules at the interf

167 potheses: the correlation of genome size and chromosome number, the origin of modern ferns from ances

168 llopolyploids resulting from the increase of chromosome number through hybridization and subsequent c

169 Cytogenetically, a reduction in diploid chromosome numbers through centric fusion in derived kar

170 lear hormone receptor helps to communicate X-chromosome number to determine nematode sex.

171 The DNA sequence and chromosome number variation data, together with prelimin

172 c data for Brassicaceae indicate that extant chromosome number variation in many plant groups, and es

173 some fusions/fissions led to the present-day chromosome number variation within the Brassiceae.

174 uncommon phenotypes among offspring owing to chromosome number variation.

175 We found evidence of sibling line-specific chromosome number variations and rapidly diverging pheno

176 ing at only a few sites in southern England, chromosome number varied from 14 to 23 in T. troglodytes

177 ntegrated lac operator arrays, we found that chromosome number varies substantially among nuclei shar

178 or normal diploid (n = 66) karyotypes; modal chromosome number was not a significant prognostic facto

179 d using flow cytometry in 79 species and new chromosome numbers were obtained.

180 d using flow cytometry in 79 species and new chromosome numbers were obtained.

181 e others fused independently and randomly as chromosome numbers were reduced in lineages leading to A

182 nes had both centrosome defects and abnormal chromosome numbers, whereas neither was observed in nont

183 ould be mainly due to the great reduction in chromosome number, which could lead to a large reduction

184 nstable genomes and increased centrosome and chromosome numbers, which are an important part of malig

185 om the C terminus, developed abnormally high chromosome numbers, which implies that Top2-Mus101 inter

186 ow that two sex-determination signals, the X chromosome number within the germ cells and a female som

187 abidopsis thaliana (2n = 2x = 10; n, gametic chromosome number; x, haploid chromosome number) and Car