ライフサイエンスコーパス: cinnamate

1 f ammonia from l-phenylalanine to give trans-cinnamate.

2 gnal response without an exogenous source of cinnamate.

3 rhizobia grown in the presence or absence of cinnamate.

4 nzyl group and 4-methoxy substitution in the cinnamate.

5 e transport inhibitor, alpha-cyano-4-hydroxy cinnamate.

6 ntents of ethyl esters of branched acids and cinnamates.

7 alpha- to (R)-beta-phenylalanine, making (E)-cinnamate (~10%) as a byproduct at steady state.

8 By contrast, when the cinnamate 4-hydroxylase (C4H) promoter was used to drive

9 erefore may be rapidly channeled through the cinnamate 4-hydroxylase (C4H) reaction to 4-coumaric aci

10 ree CYP450s involved in lignin biosynthesis: CINNAMATE 4-HYDROXYLASE (C4H), p-COUMARATE 3-HYDROXYLASE

11 with the next enzyme, the endomembrane-bound cinnamate 4-hydroxylase (C4H), to facilitate channeling,

12 Two different full-length cDNAs for cinnamate 4-hydroxylase (C4H1 and C4H2) were isolated fr

13 (phenylalanine ammonia-lyase1 [PAL1], PAL2, cinnamate 4-hydroxylase [C4H], 4-coumarate:CoA ligase1 [

14 by Phe supply and differential modulation of cinnamate 4-hydroxylase and p-coumarate 3-hydroxylase ac

15 By contrast, transcript levels for both cinnamate 4-hydroxylase and p-coumarate 3-hydroxylase we

16 Furthermore, a trans-cinnamate 4-hydroxylase mutant, which is impaired in the

17 n differed in plants downregulated in either cinnamate 4-hydroxylase or phenylalanine ammonia-lyase.

18 cs in which F5H expression was driven by the cinnamate 4-hydroxylase promoter was almost entirely syr

19 C4H1 is most homologous to a cinnamate 4-hydroxylase sequence from French bean (Phase

20 further characterized as a new inhibitor of CINNAMATE 4-HYDROXYLASE, a key enzyme of the phenylpropa

21 ript levels for phenylalanine ammonia lyase, cinnamate 4-hydroxylase, p-coumarate 3-hydroxylase, 4-co

22 an enhanced expression of the gene encoding cinnamate 4-hydroxylase, which appears to be the princip

23 ministering 100 microM alpha-cyano-4-hydroxy-cinnamate (4-CIN), a dose that blocks the neuronal monoc

24 Cinnamate-4-hydroxylase (C4H) is the first Cyt P450-depe

25 into piperonylic acid (PA), an inhibitor of CINNAMATE-4-HYDROXYLASE (C4H), the enzyme directly upstr

26 id pathway by upregulating the expression of cinnamate-4-hydroxylase (C4H), which catalyzes the secon

27 idopsis under the control of the Arabidopsis cinnamate-4-hydroxylase promoter boosted the p-coumaroyl

28 the control of the lignification-associated cinnamate-4-hydroxylase promoter, but not the commonly e

29 contrast, it shares much less homology with cinnamate-4-hydroxylase, a P450 that catalyzes the hydro

30 ilar to that obtained using alpha-cyano-4-OH-cinnamate, a well established MCT inhibitor.

31 Non-pigmented cinnamates acted as oxidase substrates and induced co-ox

32 a-damascenone, 1-octen-3-ol, acetates, ethyl cinnamate and 4-vinylguaiacol than SGW.

33 For the cinnamate and acrylate substrates studied, the catalysts

34 atalyzes the deamination of phenylalanine to cinnamate and ammonia.

35 gene completely inhibited the production of cinnamate and enterocin, whereas complementation of the

36 reas less activated substrates such as ethyl cinnamate and methyl crotonate required heating (>150 de

37 rresponding recombinant proteins showed that cinnamate and p-coumarate are their best substrates for

38 th three substrates: benzyl chloride, methyl cinnamate, and anthracene.

39 ls-Alder cycloaddition of cyclopentadiene to cinnamates arises from stacking interactions that favor

40 el use of ethyl-3-phenylprop-2-enoate (ethyl cinnamate) as a nontoxic solvent-based clearing reagent

41 pon irradiation with 366 nm light, the trans-cinnamate attached to the active-site serine isomerizes

42 Using ethyl cinnamate-cleared kidneys, we also quantified the averag

43 nzyme A (CoA) ligase motifs, a cDNA encoding cinnamate:CoA ligase (CNL) was isolated.

44 ents a bona fide 4CL, whereas the other is a cinnamate:CoA ligase (Ph-CNL).

45 In solution, these cinnamate compounds undergo light-induced (374 nm) E-Z i

46 phine oxide, a range of substrates including cinnamates, crotonates, coumarins, sulfones, and chalcon

47 sidue samples were dominated by benzoate and cinnamate derivatives and triterpenes consistent with a

48 Here we show that macrocyclic cinnamate dimers combine these productive stress-respons

49 cycloadditions between 3-hydroxyflavones and cinnamate dipolarophiles to access (-)-rocaglamide and r

50 , preclinical and clinical trials of topical cinnamate esters as proteasome inhibitors are warranted

51 bitory activity against proteasomes, whereas cinnamate esters displayed the activity.

52 alpha,beta-Unsaturated cinnamate esters irreversibly inhibited the 3CP and disp

53 act was fractionated and found to have novel cinnamate esters that inhibit proteasome activity.

54 imethylchromene and 88-98% ee for a range of cinnamate esters.

55 introduction of p-(meso-triphenylporphyrin)-cinnamate group (TPPcinnamate) on sterically hindered 10

56 Here, we show that the substitution of a cinnamate group for a pair of complementary bases provid

57 when the organic ligands did not contain the cinnamate group.

58 adiation at visible wavelengths at which the cinnamate has no absorption.

59 Thus, a cinnamate inhibitor with a biotin moiety, 1d, was synthe

60 demonstrating that the NH(2)-MIO adduct and cinnamate intermediate are sufficiently retained to cata

61 ipally rebinds to the carbon skeleton of the cinnamate intermediate to complete the alpha-beta isomer

62 which is impaired in the conversion of trans-cinnamate into para-coumarate, displayed similar defects

63 y replace native ligands with functionalized cinnamate ligands, allowing for well-defined, highly tun

64 Cinnamic acid (CA) and methyl cinnamate (MC) have attracted interest of researchers be

65 thylation, thus designating these enzymes as cinnamate/p-coumarate carboxyl methyltransferases (CCMTs

66 It involves cinnamate radical anions on the CdSe surface, formed upo

67 ted with l-[1-(3)H]arabinose or (E)-[U-(14)C]cinnamate (radiolabelling the pentosyl and feruloyl grou

68 Ethyl cinnamate rapidly cleared all tested organs, including c

69 on aerobic photolysis at 374 nm, the surface cinnamates released coumarin accompanied by rapid nanocr

70 se derivatives, 5c, has photo-cross-linkable cinnamate residues, and we have demonstrated the fabrica

71 vity and selectivity against 2-C-substituted cinnamate salts, whereas rhodium complexes of (S,S)-Ph-Q

72 vity and selectivity against 2-C-substituted cinnamate salts.

73 ts of flow on the dimerization of a range of cinnamate substrates.

74 A number of thiols carrying a substituted cinnamate tail was synthesized.

75 The cinnamate-thiols were successfully exchanged onto the Cd

76 from the excited nanocrystal to the surface cinnamate, undergoing E-Z isomerization.

77 tion of nitrones with different styrenes and cinnamates using a catalytic amount of gamma-cyclodextri

78 l 2-phenylacetate, cinnamaldehyde and methyl cinnamate were produced during the cultivation period of

79 Reactions of benzyl bromide or benzyl cinnamate with N-(benzotriazol-1-ylmethyl)arylimidoyl ch

80 mination of 3-aryl 2,3-dibromopropanoates to cinnamates with good yield.