ライフサイエンスコーパス: ciprofibrate

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1 rene, pregnenolone-16alpha-carbonitrile, and ciprofibrate.

2 eline, which was significantly attenuated by ciprofibrate (0.3+/-0.6 versus 1.5+/-1.1 U, P<0.05).

3 th full-length PPAR alpha in the presence of ciprofibrate, a synthetic ligand, and leukotriene B(4),

4 aximum induction of luciferase expression by ciprofibrate and/or 9-cis-retinoic acid is dependent upo

5 The PPAR alpha agonists, gemfibrozil, ciprofibrate, and fenofibrate, have an excellent track h

6 Treatment of LDLR-deficient mice with ciprofibrate caused a marked decrease in plasma apoB-48-

7 that synthetic PPARalpha ligands Wy-14,643, ciprofibrate, clofibrate, and others induce the nuclear

8 After 150 days of treatment with ciprofibrate, consistent with the increased plasma accum

9 t ML457 cells with monoethylhexyl phthalate, ciprofibrate ethyl ester, and clofibrate also resulted i

10 he PPs Wy-14, 643, monoethylhexyl phthalate, ciprofibrate ethyl ester, and clofibrate suggested that

11 4643, mono-ethylhexyl phthalate, clofibrate, ciprofibrate ethyl ester, and eicosatetraynoic acid each

12 , mono-ethylhexyl phthalate, clofibrate, and ciprofibrate ethyl-ester were found to be potent inducer

13 After ciprofibrate, fasting and postprandial FMD values were s

14 receptor (PPAR) alpha ligands Wy-14,643 and ciprofibrate increase the Cidea mRNA level in a PPARalph

15 patterns in HCCs from Acox1(-/-) mice and in ciprofibrate-induced HCCs were least similar to those ob

16 inant adenoviral gene transfer abolishes the ciprofibrate-induced over accumulation of apoB-48-carryi

17 Both Wy-14,643 and ciprofibrate occupied the ligand binding pocket of CAR a

18 Treatment of apoE-deficient mice with ciprofibrate or other peroxisome proliferator-activated

19 challenged with a PPARalpha ligand, such as ciprofibrate or Wy-14,643, the SRC-1(-/-) mice displayed

20 In contrast, treatment of fibroblasts with ciprofibrate or WY14643, PPAR-alpha activators, led to p

21 ited by SRC-1(+/+) wild-type mice fed either ciprofibrate- or Wy-14, 643-containing diets.

22 We examined the effect of ciprofibrate therapy on these parameters in type 2 diabe

23 rt that remnants isolated from the plasma of ciprofibrate-treated apoE-deficient mice bind to murine

24 Restoration of SR-BI expression in ciprofibrate-treated apoE-deficient mice by recombinant

25 In the present investigation we report that ciprofibrate treatment causes the down-regulation of hep

26 These findings demonstrate that ciprofibrate treatment decreases hepatic apoB mRNA editi

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