ライフサイエンスコーパス: citrate

1 different sizes (3.5 or 31 nm) and coating (citrate).

2 2'-deoxymugineic acid (DMA), esculetin, and citrate).

3 ng incubation with abscisic acid, malate, or citrate.

4 t predicted strong complexation of Tb(3+) by citrate.

5 organic chelators, such as nicotianamine and citrate.

6 r the sideorphores compared to esculetin and citrate.

7 Tartary buckwheat material were phytate and citrate.

8 ffinity substrate activity in the absence of citrate.

9 venously infused with 100 mug (58)Fe as iron citrate.

10 tal binding sites, an unprecedented role for citrate.

11 r anaplerosis and reductive carboxylation to citrate.

12 us adverse events were similar in the ferric citrate (12.0%) and placebo groups (11.2%).

13 nd the combinations of ketamine and fentanyl citrate (3.2%; OR, 6.5; 95% CI, 2.5-15.2) and ketamine a

14 rbonate (4.0g.L(-1)), chloride (5.0g.L(-1)), citrate (6.5g.L(-1)), hydroxide (4.0g.L(-1)), hypochlori

15 at each time-point compared to patients with citrate accumulation (-9.8%, -20.5%, and 2.3%, respectiv

16 ve and significantly higher in patients with citrate accumulation compared to those without (+0.2 vs

17 We studied the prediction of citrate accumulation during continuous veno-venous hemod

18 Risk of citrate accumulation during regional citrate anticoagula

19 The frequency of citrate accumulation during the first 48 hours of therap

20 Citrate accumulation is a major complication of regional

21 spergillus niger, the molecular mechanism of citrate accumulation is only partially understood.

22 rlactatemia (>/= 4 mmol/L), the frequency of citrate accumulation was 0.77%, 2.70%, and 6.33%, respec

23 ing characteristics-area under the curve for citrate accumulation was observed for 12-hour values of

24 ve study and screened for metabolic signs of citrate accumulation.

25 oncentration was 0.789 for the prediction of citrate accumulation.

26 gain a genome-wide view of the mechanism of citrate accumulation.

27 hould be considered in assessing the risk of citrate accumulation.

28 ensional structure and coordination modes of citrate, acetate, succinate and glutarate to AuNPs is ob

29 ificantly more patients randomized to ferric citrate achieved the primary end point (61 [52.1%] versu

30 carrier family 13 member 5, which transports citrate across cell membranes, halts liver cancer cell g

31 These data suggest that citrate acts on the IGF-1R-AKT-PTEN-eIF2a pathway.

32 We found that citrate administration inhibited A549 lung cancer growth

33 Critically, we show experimentally that citrate also inhibits the exoribonuclease activity of ba

34 sculitis were trimethylamine N-oxide (TMAO), citrate and 2-oxoglutarate.

35 casein) was found at 4.9mM phosphate, 4.0mM citrate and 26.1mM calcium.

36 gcasein) was found at 9.7mM phosphate, 5.5mM citrate and 30.0mM calcium, while optimal loading of vit

37 ere stabilized with a 0.8 nm layer of sodium citrate and a 0.05 nm (one wash) or 0.025 nm (two wash)

38 t system than maize but greater exudation of citrate and acid phosphatase, suggesting a greater capac

39 have found that therapy including tamoxifen citrate and aromatase inhibitors (AIs) reduces CBC risk.

40 eraction between alpha-hydroxycarboxylate of citrate and boronic acids of BDBA.

41 lability from two types of enriched (calcium citrate and calcium carbonate) milks homogenized to a na

42 calcium carbonate, calcium chloride, calcium citrate and calcium sulphate to 100g of raw homogenates

43 We reveal channelling of citrate and fumarate in isolated potato mitochondria by

44 or suppressor gene use glutamine to generate citrate and lipids through reductive carboxylation (RC)

45 nd of inhibitors of crystallization, such as citrate and magnesium.

46 nsporters AtALMT and AtMATE, responsible for citrate and malate secretion, respectively, were elevate

47 uces root secretion of organic acids such as citrate and malate.

48 and 15 (12.9%) patients treated with ferric citrate and placebo, respectively.

49 Citrate and tartarate based food preservatives can be us

50 ated that soluble ferric iron (Fe(3+), as Fe-citrate) and nanoparticulate forms of Fe(3+) and Mn(4+)

51 ion of phosphoenolpyruvate (P-enolpyruvate), citrate, and aconitate, which was consistent with allost

52 nanoparticle capping agents-such as tannate, citrate, and borate-which does not seem to have been don

53 Mutant LCN2 strips iron from transferrin and citrate, and delivers it into the urine.

54 ding domain of MCP2901 (MCP2901LBD) bound to citrate, and weakly to gentisate and 4-hydroxybenzoate.

55 oton and/or sodium-driven transport of (14C)-citrate anion, as well as the organic monovalent cation,

56 sine at C-terminus and causes aggregation of citrate anion-stabilized silver nanoparticles (AgNPs) in

57 nuous veno-venous hemodialysis with regional citrate anticoagulation by initial lactate concentration

58 mulation is a major complication of regional citrate anticoagulation during continuous renal replacem

59 Risk of citrate accumulation during regional citrate anticoagulation in a well-selected cohort of pat

60 fety and efficiency of heparin-free regional citrate anticoagulation of the dialysis circuit using a

61 cute kidney injury and treated with regional citrate anticoagulation-continuous veno-venous hemodialy

62 layer facing draw solution) using trisodium citrate as draw solute, most likely due to the unique sw

63 an open conformation with both carbonate and citrate as synergistic anions at the metal binding sites

64 the majority of studies only concentrate on citrate as the capping agent.

65 our alternative plasticizers (acetyltributyl citrate (ATBC), bis(2-propylheptyl) phthalate (DPHP), bi

66 he assay is based on inducing aggregation of citrate AuNPs decorated with a specific nucleic acid pro

67 genitor cell homing and angiogenesis, from a citrate-based antioxidant thermoresponsive polymer would

68 y to characterize Fe plaque using dithionite-citrate-bicarbonate (DCB) extraction and elemental analy

69 cate that residues located near the putative citrate binding site, G228, V231, V232, and G409, affect

70 re, residues located outside of the putative citrate binding site, Q77 and T86, may also play a role

71 We show that upon citrate binding, the PAS domain contracts, resulting in

72 ming that TM helix motions are linked to the citrate-binding event.

73 membrane-embedded CitA construct slows down citrate-binding kinetics by at least a factor of 60, con

74 urthermore, bioinformatics data, showing key citrate-binding motifs conserved across a broad range of

75 r, and surfactant (Tween 80) into 5mM sodium citrate buffer (pH 3.5).

76 r 110-nm AgNP (C20 or C110, respectively) or citrate buffer alone for 6 hr.

77 g/kg of either 20-nm citrate-coated AgNPs or citrate buffer using oropharyngeal aspiration.

78 reptozotocin, and control animals were given citrate buffer.

79 First, sample extraction was done with MeCN:citrate buffer:NaHCO3 followed by phase separation with

80 prague-Dawley rats were exposed nose-only to citrate-buffered 20- or 110-nm AgNP (C20 or C110, respec

81 ile acidified with acetic acid (1%, v/v) and citrate-buffered salts followed by dispersive solid phas

82 Itch induced by acidic citrate, but not alpha-methyl-5-hydroxytryptamine, chlor

83 ther the addition of a citric acid/trisodium citrate (CA/TSC) mixture before extrusion increases iron

84 We also show that citrate can bind to both TmNadA K219R and its Y21F varia

85 Our data suggests that citrate can inhibit tumor growth in diverse tumor types

86 y, a colorimetric sensor array consisting of citrate-capped 13 nm gold nanoparticles (AuNPs) has been

87 sible reaction pathway for the conversion of citrate-capped Ag nanospheres to AgAu nanocages; importa

88 o uptake and intracellular transformation of citrate-capped AgNPs by microglia, as well as their effe

89 ed, while the apparent size distributions of citrate-capped AgNPs changed rapidly.

90 a five-fold greater salt concentration than citrate-capped AuNPs and the d-AuNPs were stabilized by

91 The BDBA-induced aggregation of citrate-capped AuNPs can be paired with the glucose oxid

92 was effective in driving the aggregation of citrate-capped AuNPs through an interaction between alph

93 s incapable of triggering the aggregation of citrate-capped AuNPs.

94 H2O2 prohibited BDBA-induced aggregation of citrate-capped AuNPs.

95 Retention of citrate-capped nAu on 300-700 degrees C pecan shell bioc

96 We report citrate-capped platinum nanoparticles (Pt NPs) as oxidas

97 To confirm oxidase-like activity of citrate-capped Pt NPs, their activity toward oxygen redu

98 through direct adsorption on the surface of citrate-capped Pt NPs.

99 solid-supported adsorption steps including a citrate chelation method developed to remove >99.9% of t

100 ADC and two metabolite ratios (citrate [Cit], spermine [Spm], and creatine [Cr] to chol

101 in size distributions have been observed for citrate- (cit) and polyvinylpyrrolidone- (PVP) capped si

102 Poly (polyethylene glycol citrate-co-N-isopropylacrylamide) (PPCN) was synthesized

103 e of Ag from polyvinylpyrrolidone (PVP)- and citrate-coated 80 nm nAg in aerobic WW effluent and mixe

104 Here we demonstrate that citrate-coated Ag NPs of size 20 nm, when applied at a s

105 act with test vessels and algal cells, while citrate-coated AgNPs have a tendency to dissolve.

106 received doses of 0.25 mg/kg of either 20-nm citrate-coated AgNPs or citrate buffer using oropharynge

107 h component, namely, 20, 40, and 60 nm sized citrate-coated and 40 and 60 nm sized PVP-coated NPs, co

108 0 mg.kg(-1) of dissolved Ce2(SO4)3, bare and citrate-coated CeO2 nanoparticles.

109 ion of the particle number and size of 60 nm citrate-coated gold nanoparticles suspended in high-puri

110 40 nm sized polyvinylpirrolidone (PVP)- and citrate-coated NPs, 40 nm sized polyethylene glycol (PEG

111 , 40 nm sized polyethylene glycol (PEG)- and citrate-coated NPs, and 60 nm sized PVP- and citrate-coa

112 citrate-coated NPs, and 60 nm sized PVP- and citrate-coated NPs.

113 the soil poor in organic matter, the organic citrate coating significantly enhanced the phytoavailabi

114 positive correlation with the metal-ligand (citrate) complex formation constant (Kf).

115 Fe/CA molar ratios </=0.5, kaolinite-Fe(III)-citrate complexation preferentially occurred, but less C

116 infusions as Ni(2+) and Ni-gluconate and Ni-citrate complexes.

117 compounds is highly dependent on the ambient citrate concentration and our detailed mechanism of acti

118 ach) were drawn and analyzed for glucose and citrate concentrations on each of 2 consecutive days.Par

119 an +/- SEM pre- and postfilter venous plasma citrate concentrations were 1 +/- 0.1 and 3.1 +/- 0.2 mm

120 Tb(3+) could be effectively recovered using citrate, consistent with thermodynamic speciation calcul

121 Dialysis anticoagulation with calcium-free citrate-containing dialysate and calcium reinjection acc

122 of the dialysis circuit using a calcium-free citrate-containing dialysate, with calcium reinjected ac

123 dominantly in the zero oxidation state after citrate coordination, although trace amounts of Au(delta

124 caffeine released from hydrogel decreased by citrate cross-linking and was higher at neutral pH than

125 transfer, detoxification of anion radicals, citrate cycle, and tetrapyrrole biogenesis.

126 All subjects received 1000 mg calcium citrate/d, with vitamin D administered weekly at an equi

127 s also revealed that with the help of sodium citrate degradation, the printed HCECs showed a higher p

128 optimizes the analytical performance of the citrate-derived sensor materials for the detection of ch

129 gnostic solutions, we recently established a citrate-derived synthesis platform for the development o

130 fy the systemic caloric contribution of acid-citrate-dextrose regional anticoagulation and dextrose-c

131 Trisodium citrate did not nonetheless influence the gel hardness e

132 sults point to a primary role of MtMATE67 in citrate efflux from nodule cells in response to an Fe si

133 Adding trisodium citrate either alone or as part of a mixed chelating sal

134 bound VcINDY in complexes with succinate and citrate, elucidating the binding sites for substrate and

135 ) adsorption capacity was observed following citrate elution, enabling consecutive adsorption/desorpt

136 ntly (P<0.05) better than nano-sized calcium citrate-enriched-milk.

137 ensing channels/receptors involved in acidic citrate-evoked itch.

138 Best-fit rates for Citrate-Fe(II) mediated O2 to O2(-) and H2O2 to OH were

139 systems for elemental iron (efeUOB), ferric citrate (fecCDEF), and petrobactin (fpbNOPQ) are induced

140 suspensions were crosslinked with trisodium citrate for either 0 or 17h, gelled and then freeze-drie

141 s evaluating Vitamin B12 (VB12) with Ti(III)-citrate for potential use in in situ remediation of perf

142 in spheroids, whereas reductive formation of citrate from glutamine was enhanced.

143 celerated biosynthesis and transportation of citrate from mitochondria to the cytosol, leading to cyt

144 e transporter, plays a key role in importing citrate from the circulation into liver cells.

145 entate (1kappaO(1)) mode is favoured at high citrate:gold ratios.

146 ached statistical significance in the ferric citrate group, including the mean relative change in hem

147 uced by complex formation between Pb(2+) and citrate groups localized on the AgNPs, reducing surface

148 Metabolites such as succinate and citrate have a direct impact on the functioning of macro

149 0.89, 3.0/1000 CVC days) in the taurolidine-citrate-heparin and heparin arm, respectively, tending t

150 In the taurolidine-citrate-heparin arm, no CRBSIs occurred, whereas 7 CRBSI

151 o are life dependent on HPS, the taurolidine-citrate-heparin catheter lock demonstrates a clinically

152 sts.Twenty patients received the taurolidine-citrate-heparin lock and 21 received the heparin lock, w

153 icrobial catheter lock solution, taurolidine-citrate-heparin, compared with heparin 100 IE/mL on CRBS

154 rated and formaldehyde-, hydrogen peroxide-, citrate-, hydroxide- and starch-adulterated samples was

155 o be modulated by the Krebs cycle metabolite citrate in Escherichia coli.

156 PF-06649298) which inhibits the transport of citrate in in vitro and in vivo settings via a specific

157 ved pyruvate is oxidized via PDH to generate citrate in the mitochondria.

158 linking over time by the generated trisodium citrate increased the K value.

159 Further studies indicated that citrate induced tumor cell differentiation.

160 r ASIC3 nor TRPA1, is involved in the acidic citrate-induced scratching response.

161 lated mIndy expression, enhanced cytoplasmic citrate influx, and augmented hepatic lipogenesis in viv

162 Moreover, we found that citrate inhibited IGF-1R phosphorylation.

163 lux of the anionic form of the organic acid, citrate, into the soil rhizosphere, chelating Al(3+) ion

164 ow, we found that measurement of the glucose/citrate ion signal ratio accurately predicted cancer whe

165 In the liver, citrate is a key metabolic intermediate involved in the

166 Citrate is an important signaling molecule that regulate

167 r showing that glucose levels are high while citrate is low, we found that measurement of the glucose

168 Citrate is used for the synthesis of the antimicrobial m

169 even tricarboxylic acid cycle intermediates (citrate, isocitrate, 2-oxoglutarate, succinate, fumarate

170 likely formed strong hydrogen bonds with the citrate layer of nAu.

171 Uniform organic (primarily citrate ligands) layer on nAu was observable by TEM, and

172 e-electrode voltammetric cell with a bismuth citrate-loaded graphite working electrode.

173 s been previously shown to modulate both ATP-citrate lyase (ACL) and AMP-activated protein kinase (AM

174 olic acetyl CoA (Ac-CoA), is produced by ATP-citrate lyase (ACLY) from mitochondria-derived citrate o

175 In this study, we report that nuclear ATP-citrate lyase (ACLY) is phosphorylated at S455 downstrea

176 ATP-citrate lyase (ACLY), a key enzyme for lipid synthesis,

177 g proteins in breast cancer, identifying ATP-citrate lyase (ACLY), an enzyme in the de novo lipogenes

178 se (FASN), acetyl-CoA carboxylase (ACC), ATP citrate lyase (ACLY)].

179 elongation in tumour cells by targeting ATP citrate lyase and fatty acid elongase 6, as well as impa

180 lly deubiquitinates and thus upregulates ATP citrate lyase and oxoglutarate dehydrogenase, two key en

181 io of ATP/ADP, phospholipid content, and ATP citrate lyase expression.

182 Both forms of RuBisCO, together with ATP citrate lyase genes in the rTCA cycle, increase with dis

183 oteins such as PCSK9, HMG-CoA reductase, ATP citrate lyase, and NPC1L1.

184 the CRM hydroxycitrate, an inhibitor of ATP citrate lyase, induced the depletion of regulatory T cel

185 e show that acetyl-CoA synthase, rather than citrate lyase, is essential for acetyl-CoA synthesis in

186 fat diet (HFD) results in suppression of ATP citrate-lyase levels in tissues such as adipose and live

187 ATP citrate-lyase produces acetyl-CoA in the nucleus and cyt

188 Two cytosol ATP-citrate lyases, which take part in the cycle of citrate

189 Citrate, made either from (13)C proline or from (13)C gl

190 ces were studied: calcium carbonate, calcium citrate malate, calcium phosphate and calcium bisglycina

191 Particularly, the citrate-malate shuttle supplies cytosolic acetyl-CoA and

192 Dietary supplementation with citrate may be beneficial as a cancer therapy.

193 Aerogel hardness was increased by the citrate-mediated crosslinking, whereas its adhesiveness

194 re, we provide evidence for the existence of citrate-mediated inhibition of ribonucleases in all thre

195 ndependence requires a fundamental change in citrate metabolism, initiated by IDH1-dependent reductiv

196 :1 and urea) and third-trimester (hexose and citrate) metabolite screening predicted tPE with an area

197 ect to an in situ generation of soluble FePP citrate moieties during extrusion and/or cooking because

198 mpare the safety and efficacy of oral ferric citrate (n=117) and placebo (n=115).

199 sting of phenylalanine, glutamine, tyrosine, citrate, N-acetyl-glycoproteins and TMAO was selected, w

200 ouped by endocrine therapy status (tamoxifen citrate only, AI only, both, or neither).

201 trate lyase (ACLY) from mitochondria-derived citrate or by acetyl-CoA synthetase short-chain family m

202 nanoparticles (AuNPs) stabilized with either citrate or by low-generation dendrimers rapidly grow dur

203 Caffeine citrate or placebo until drug therapy for apnea of prema

204 ds) and nanoparticle surface chemistry (PVP, citrate, or humic acid) on alpha, and found a strong dep

205 In oocytes, MtMATE67 transported citrate out of cells in an Fe-activated manner.

206 eased demand for these metabolites decreases citrate oxidation through the tricarboxylic acid cycle,

207 Tween 80; pH7.4 PBS containing 1.0% triethyl citrate (PBStc); and pH7.4 HEPES buffered-saline contain

208 influenced strongly vitamin C degradation in citrate-phosphate buffer but not in the apple puree seru

209 liter) and Marshall's Solution (hyperosmolar citrate, pound10 per liter).

210 t accumulated six times the concentration of citrate present in wild-type bacteria.

211 acing revealed that in spheroids, isocitrate/citrate produced reductively in the cytosol could enter

212 ative genomics and transcriptome analysis of citrate-producing strains-namely, A. niger H915-1 (citra

213 metabolism at the pyruvate node to moderate citrate production and indeed, the DeltadacA mutant accu

214 Despite a long and successful history of citrate production in Aspergillus niger, the molecular m

215 r influence on pH decrease nor difference in citrate production were observed.

216 active disease, with the urine myo-inositol:citrate ratio being tightly correlated with active renal

217 After brief tissue preparation, the glucose/citrate ratio can be recorded on a tissue sample in 1 mi

218 Interestingly, citrate regressed Ras-driven lung tumors.

219 f is transported into cells and that sTf and citrate regulate the metal's blood speciation and attenu

220 Iron citrate rescued the lymphocyte defects, and expression o

221 leukocyte scintigraphy (LS), and Gallium-67 citrate scintigraphy for the diagnosis of CIED infection

222 No studies for (67)Ga citrate scintigraphy met the inclusion criteria.

223 ural rearrangements in the extracytoplasmic, citrate-sensing Per-Arnt-Sim (PAS) domain of HK CitA are

224 Indeed, supplying exogenous citrate significantly enhanced Ga tolerance.

225 thesis and reduced expression of the hepatic citrate SLC13A5 transporter has been shown to improve me

226 By altering the mole ratio of sodium citrate/sodium alginate, the degradation time of the bio

227 ELT scavenges iron citrate species faster than deferasirox, but rapidly don

228 herical multilayer NPs, was applied to model citrate stabilized Au/Ag-core/shell nanoparticles (NPs).

229 ilized gold nanoparticles, (2) directly onto citrate stabilized gold nanoparticles and (3) directly o

230 Asparagine stabilized gold nanoparticles and citrate stabilized gold nanoparticles via different immo

231 5 antibody - (1) after EDC-NHS activation of citrate stabilized gold nanoparticles, (2) directly onto

232 he effect of aggregation on the oxidation of citrate-stabilized Au nanoparticles (NPs) attached elect

233 ependent electrophoretic deposition (EPD) of citrate-stabilized Au nanoparticles (NPs) onto indium-ti

234 Two sizes of citrate-stabilized AuNPs (5 and 12 nm) were functionaliz

235 For example, citrate-stabilized AuNPs and AuNPs encapsulated within s

236 Citrate-stabilized particles degraded during analysis an

237 on the stochastic amperometric detection of citrate-stabilized silver nanoparticles in aqueous solut

238 which liberates protons and neutralizes the citrate stabilizer, leading to precipitation of the Au N

239 eriments, including foliar iron application, citrate supplementation and iron deficiency treatment, i

240 roximately 25%) and the mitochondrial enzyme citrate synthase ( approximately 20%).

241 se reaction and anaplerotic pathways) and Re-citrate synthase (Ccar_06155) was a key enzyme in its tr

242 ein in mitochondrial extracts, identified as citrate synthase (CS).

243 dative function was impaired, with decreased citrate synthase activity and spare respiratory capacity

244 d glucose tolerance, liver NAD(+) levels and citrate synthase activity in offspring.

245 Citrate synthase activity was lower (P < 0.0001) and cyt

246 s exercise training improved cardiac output, citrate synthase activity, and peak tissue diffusing cap

247 Measurements of renal cardiolipin levels, citrate synthase activity, rotenone-sensitive NADH oxida

248 s, and mitochondrial densities, assessed via citrate synthase activity, were consistent between group

249 ntrast, PGC-1a expression did not change and citrate synthase decreased by approximately 30% in SKM-D

250 in assessing rates of hepatic mitochondrial citrate synthase flux (V CS) and pyruvate carboxylase fl

251 ition, there were striking increases in both citrate synthase gene expression and enzymatic activity

252 anced low-temperature activity for A. pernix citrate synthase that is synthesized during leucine to m

253 Inactivation of citrate synthase, but not down-stream enzymes suppressed

254 Corroborated by data referring to citrate synthase, these results confirm the transitory (

255 drial markers transcription factor A (TFAM), citrate synthase, voltage-dependent anion channel (VDAC)

256 between the cell growth stage (6 h) and the citrate synthesis stage (12 h, 24 h, 36 h, and 48 h).

257 rate lyases, which take part in the cycle of citrate synthesis, were up-regulated, and may coordinate

258 and an aconitase family protein involved in citrate synthesis.

259 a substantial net uptake of both glucose and citrate that delivered exogenous energy and provided app

260 actosidase activity (S-Gal + ferric ammonium citrate) that produces both optical and MR contrast.

261 d with a decrease in intracellular levels of citrate, the ratio of ATP/ADP, phospholipid content, and

262 n of competing metals; and for esculetin and citrate, the synergistic effect was temporary (less than

263 Caffeine citrate therapy for apnea of prematurity reduces the rat

264 In this study we have tested the efficacy of citrate therapy in various cancer models.

265 e-producing strains-namely, A. niger H915-1 (citrate titer: 157 g L(-1)), A1 (117 g L(-1)), and L2 (7

266 patients with NDD-CKD, we found oral ferric citrate to be a safe and efficacious treatment for iron

267 hree modes are simultaneously present at low citrate to gold ratios, while a monocarboxylate monodent

268 e, we report the whole-cell bioconversion of citrate to itaconate with enhanced aconitase and cis-aco

269 el incubated with a medium containing sodium citrate to obtain degradation-controllable cell-laden ti

270 r results provide the first glimpse into the citrate-transferrin synergism in the regulation of Ti(IV

271 ite, G228, V231, V232, and G409, affect both citrate transport and inhibition of citrate uptake by co

272 Likewise, MtMATE67-mediated citrate transport into the symbiosome space would increa

273 Inhibition of the sodium-coupled citrate transporter (NaCT or SLC13A5) has been proposed

274 5) encoding for a plasma membrane-associated citrate transporter expressed highly in the liver, prote

275 We have characterized a nodule-specific citrate transporter of the multidrug and toxic compound

276 d size, as did deletion of the mitochondrial citrate transporter protein.

277 The Na(+)/citrate transporter, NaCT (SLC13A5), is a therapeutic ta

278 mily 13 member 5 (SLC13A5), a sodium-coupled citrate transporter, plays a key role in importing citra

279 inate and citrate, which predict how a human citrate-transporting DASS may interact with its bound su

280 Additionally, citrate treated tumor samples showed significantly highe

281 In vitro studies suggested that citrate treatment inhibited AKT phosphorylation, activat

282 ns of disodium tartarate (DST) and trisodium citrate (TSC) in the temperature range (288.15-318.15)K

283 e (TMAO), glutamine, N-acetyl-glycoproteins, citrate, tyrosine, phenylalanine, isoleucine, valine and

284 prevented the stimulating effect of IL-6 on citrate uptake and reduced hepatic lipogenesis.

285 ect both citrate transport and inhibition of citrate uptake by compounds 2: and 4: V231 appears to di

286 Net citrate uptake from the CVVH circuit was 60 +/- 2 mg/min

287 e-dependent inhibition of radioactive [(14)C]citrate uptake in liver and kidney in vivo, resulting in

288 Although inhibition of hepatic extracellular citrate uptake through SLC13A5 has been suggested as a p

289 nd PF-06761281, using a combination of (14)C-citrate uptake, a membrane potential assay and electroph

290 1; P = .01) independent of age and tamoxifen citrate use.

291 ugh the Krebs cycle, proline is used to make citrate via reductive carboxylation.

292 between this surface and a bound molecule of citrate was observed in a crystal structure.

293 Phosphocreatine/creatine and citrate were identified at higher concentrations after c

294 g alpha-KG, succinate, fumarate, malate, and citrate were observed in TGF-beta1-differentiated myofib

295 lement thorium and counterions phosphate and citrate were separated effectively from the REEs in the

296 nthesized by reduction of AgNO3 by trisodium citrate were used as SERS-active substrate to quantify t

297 se involved inhibition of pyruvate kinase by citrate, which accumulated and thereby curtailed glycoly

298 nt of VcINDY in complexes with succinate and citrate, which predict how a human citrate-transporting

299 ilico molecular docking studies predict that citrate will bind not only to bacterial PNPases from E.

300 319.8 mM of itaconate (41.6 g/L) from 500 mM citrate without any buffer system or additional cofactor