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1 DNA adducts are mutagenic and clastogenic.
2 uding its ability to form free radicals, its clastogenic activity, and its estrogenic activity, contr
3 ated histone H2AX (-H2AX) as compared with a clastogenic agent, camptothecin, indicating that the qua
7 ive activity of topoisomerases can result in clastogenic and/or lethal DNA damage in which the topois
10 FANCG disruption also resulted in increased clastogenic damage on irradiation, but only FANCG disrup
11 FANCC and FANCG disruption caused increased clastogenic damage, G2/M arrest, and decreased prolifera
14 e degree of cellular hypersensitivity to the clastogenic effect of diepoxybutane and severity of clin
15 ators and radiotherapy patients can induce a clastogenic effect on naive cells, showing indirect indu
16 show that Aag protects against the toxic and clastogenic effects of 1,3-bis(2-chloroethyl)-1-nitrosou
19 ficantly to protection against the toxic and clastogenic effects of several chemotherapeutic nitrogen
20 atopoietic progenitor cells to the toxic and clastogenic effects of the antitumor agents 1,3-bis(2-ch
22 cells (death-inducing and bystander effects, clastogenic factors) and perpetuate genomic instability
23 nd while some studies suggest that it may be clastogenic, its carcinogenicity has not been demonstrat
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