ライフサイエンスコーパス: clearance rate

1 at is partially attributable to increased LH clearance rate.

2 abolically stable and displayed a low plasma clearance rate.

3 erefore not represent a direct indication of clearance rate.

4 and insulin levels and an increased glucose clearance rate.

5 ucose tolerance tests showed a rapid glucose clearance rate.

6 p levels than Cs, indicating reduced insulin clearance rate.

7 ty were established to improve relaxivity or clearance rate.

8 is at diagnosis showed a significantly lower clearance rate.

9 atinine excretion then yields the creatinine clearance rate.

10 min after agent administration by examining clearance rates.

11 the tumor extracellular matrix, and systemic clearance rates.

12 moval is associated with up to >90% calculus clearance rates.

13 me lower over STIs, there were no changes in clearance rates.

14 CTL count and either viral rebound rates or clearance rates.

15 ine data on troponin T levels and creatinine clearance rates.

16 without mutation in the region showed normal clearance rates.

17 ility in plasma free dobutamine and dopamine clearance rates.

18 elop a relationship between bivalve size and clearance rates.

19 human immunity is the primary determinant of clearance rates.

20 come measures were clinical and histological clearance rates.

21 e chemically stable, and have normal in vivo clearance rates.

22 neutral or anionic liposomes have more rapid clearance rates.

23 lence with age is attributable to increasing clearance rates.

24 he design of synthetic heparins with desired clearance rates.

25 A small difference in ethanol clearance rate (0.1 mg/ml/h) likely had little impact on

26 245 minutes (T 1/2 b; SD 76.min.); metabolic clearance rate = 0.65%/minute.

27 The spontaneous viral clearance rate (18%) in this contemporary study was simi

28 resulting in a significantly higher glucose clearance rate (+21 +/- 2%).

29 uorouracil group also had higher complete AK clearance rates (38% vs 17% at 6 months) and fewer spot

30 asma concentration, 1.20 +/- 0.62 microg/mL; clearance rate, 6.33 +/- 6.41 L/h; elimination half-life

31 The cytoplasmic Ca(2+) clearance rate affects neuronal excitability, plasticity

32 The spontaneous viral clearance rate after 6 months of infection was 18% (95%

33 , which were associated with a slow parasite clearance rate after treatment with artemisinin derivati

34 Changes in transalveolar DTPA clearance rates after balloon occlusion of pulmonary art

35 The model estimated HDTX clearance rate agreed with in vitro literature values, s

36 Significant normalization of local DTPA clearance rates also occurred in the presence of a throm

37 There were no differences in clearance rates among the intravenous group, IVIG group,

38 the Thiele modulus are ratios of the plasma clearance rate and antibody catabolism, respectively, to

39 highly significant correlation between VLDL clearance rate and mean atherosclerotic plaque size.

40 radioimmunotherapy by manipulating the blood clearance rate and the catabolism of the radiolabel.

41 ry the drug in living organisms with reduced clearance rate and toxicity.

42 The clearance rate and tumor-to-organ ratios were influenced

43 Literature-reported or predicted values for clearance rates and absorbed doses were used in the PK/P

44 essive regimen (n = 12), we calculated viral clearance rates and generation times and estimated the l

45 t transporter phosphorylation, enhanced 5-HT clearance rates and hyperserotonemia.

46 Estimates of clearance rates and liver and lesion uptake were made fo

47 interest such as biomarker intravasation and clearance rates and protein half-lives in the bloodstrea

48 depending on the patient-specific whole-body clearance rates and the times between fractions.

49 dimensional images of radionuclide kinetics (clearance rate) and cumulated activity.

50 ation was estimated as the reciprocal of the clearance rate, and acquisition rates were estimated on

51 Phase 1/2 declines, free virus clearance rate, and infected hepatocyte death rate were

52 response to PfEMP1, differences in parasite clearance rates, and heterogeneity in the rate at which

53 per minute) approached the rapid mucociliary clearance rates (approximately 2.0% per minute) reported

54 eatment with amiloride increased mucociliary clearance rates (approximately twofold) after inhalation

55 irways airway surface liquid (ASL) depth and clearance rates are both increased by fluid secretion.

56 Our estimates of progression and clearance rates are consistent with the findings of surv

57 ripsy success rates vary from 50 to 90%, but clearance rates are often delayed.

58 ent glycans in the Fc region showed the same clearance rate as demonstrated previously.

59 These slow clearance rates associate with enhanced survival rates o

60 Creatinine clearance rate at 6 months and 3 years and chronic allog

61 Human papillomavirus 16/18 clearance rates at 12 months were 48.8% (86/177) in the

62 ar metabolic enzyme activities and metabolic clearance rates between red- and white-blooded Antarctic

63 wever, dynamic PET did not show differential clearance rates between treatment and control groups.

64 ng demonstrated a marked difference in brain clearance rates between wild-type and mrp1 knockout mice

65 arasite genetics is associated with parasite clearance rate but does not account for all variation.

66 ice) displayed comparable vaginal chlamydial clearance rates but significantly reduced oviduct pathol

67 ce effects at the physiological level (algal clearance rate), but induced DNA damage, as determined b

68 We measured heritability of clearance rate by evaluating patients infected with iden

69 Notably, clearance rates by 24 months were 41% and 94% in the hig

70 where F is the RBF, k is the tissue-to-blood clearance rate, C is the PET concentration, and C(a) is

71 r the accelerated radioaerosol transalveolar clearance rates caused by acute balloon occlusion of the

72 ion was rapid, with a half-life and systemic clearance rate (Cl(S/F)) averaging 1.8 hours and 115 mL/

73 The absolute oral bioavailability (F), clearance rate (CL), average blood concentration (C[av])

74 Mean particle clearance rate (Clr in %/min) through 50 min for placebo

75 nd 28 days after injection and delayed blood clearance rates compared with native AAV.

76 1), which was very similar to the mean viral clearance rate constant after drug resumption of 0.35 (0

77 The k'2 (clearance rate constant from the reference region) requi

78 decline with a minimum estimate of the viral clearance rate constant of 2.8 per day, corresponding to

79 Virion clearance rate constants were 0.0063/min (9.1/day) to 0.

80 (11)C-acetate clearance rates correlated moderately with quantitative

81 sinin resistance results in reduced parasite clearance rates (CRs) after treatment.

82 Accurate measurement of malaria parasite clearance rates (CRs) following artemisinin (ART) treatm

83 A faster pulmonary clearance rate did not simply reflect the presence of ch

84 The clearance rate, dissolved uptake rate (for Cd and Zn), a

85 Mean baseline peripheral clearance rates during the first 40 min of clearance mea

86 in sensitivity index Stumvoll, and metabolic clearance rate estimation without demographic parameters

87 However, this clearance rate excludes the highly variable lag phase, w

88 duced TG levels by increasing the fractional clearance rate (FCR) of VLDL TGs from the circulation, w

89 received their own LDL), the LDL fractional clearance rate (FCR) was reduced in fish oil-supplemente

90 At the end of each period, fractional clearance rates (FCRs) and production rates (PRs) of apo

91 vels of ManR and ASGR expression control the clearance rate for glycoproteins bearing recognized glyc

92 administration increased the basal metabolic clearance rate for leucine (approximately 28%, P < 0.05)

93 In this study, we measured in vitro hepatic clearance rates for 50 IOCs using a pooled batch of live

94 Clearance rates for both Abeta42 and Abeta40 were impair

95 Clearance rates for C12-IOCs were higher than those for

96 We have shown that clearance rates for glycoproteins such as luteinizing ho

97 Clearance rates for HPV-16/18 infections at 6 months wer

98 the literature by estimating progression and clearance rates for non-16 and non-18 high-risk types.

99 the charged terminal group, with the highest clearance rates for tertiary amines and sulfates and no

100 The clearance rate from the circulation was increased with t

101 lky dibenzocyclooctyne group in AP decreased clearance rates from circulation.

102 and (131)I-labeled fragments revealed blood clearance rates from slowest to fastest as follows: wild

103 , endogenous glucose production, and glucose clearance rate (GCR).

104 % CI, 1.002-1.017; P = .01) and a creatinine clearance rate >/=53 mL/min (OR, 1.024; 95% CI, 1.006-1.

105 Only baseline creatinine clearance rate >/=53 mL/min predicted 6-week survival (P

106 es of TG mice exhibited normal basal glucose clearance rates; however, under insulin-stimulated condi

107 slightly better than 3/3 VLDL, but the VLDL clearance rate in 4/4 mice was half that in 3/3 mice.

108 onsistent with this idea, we found that 5-HT clearance rate in hippocampus was dramatically reduced i

109 sensitivity mediated by an increased glucose clearance rate in insulin-responsive tissues under insul

110 The slow clearance rate in men (based on 6 months' follow-up) was

111 ed that MG(min)-LDL had a similar fractional clearance rate in plasma to unmodified LDL but increased

112 with the data examined here for the in vivo clearance rate in the rat.

113 me scale of minutes, we determine the plasma clearance rate in the wild-type mouse, using time-resolv

114 estern Cambodia, detected as a slow parasite clearance rate in vivo.

115 motif showed remarkably reduced circulatory clearance rates in an animal model.

116 try (chronoamperometry) to examine serotonin clearance rates in brain liposomes (synaptosomes) prepar

117 gnificance is expected to be increased mucus clearance rates in cholinergically stimulated airways.

118 Lower viral clearance rates in circulating blood may explain the phe

119 ; however, it does not account for prolonged clearance rates in patients without detectable viremia.

120 vWF clearance rates in rat plasma were determined by quantit

121 measured Abeta42 and Abeta40 production and clearance rates in the CNS of participants with Alzheime

122 Absence of SLC10A4 led to slower dopamine clearance rates in vivo, which resulted in accumulation

123 haride structures in the Fv region and their clearance rates in vivo.

124 e were no differences in plasma TG turnover (clearance rate) in response to either treatment, consist

125 The blood glucose clearance rate increased significantly at day 20 (P < 0.

126 Clearance rates increased with CeO2 concentration but de

127 Clearance rates increased with year of age, adjusted for

128 parasite survival rates and in vivo parasite clearance rates indicate that K13-propeller mutations ar

129 dition, basal and insulin-stimulated glucose clearance rates into insulin-sensitive peripheral tissue

130 ial proportion (56%-58%) of the variation in clearance rate is explained by parasite genetics.

131 e DMPC gel-to-liquid crystal transition, the clearance rate is independent of the protein helical con

132 Our estimated clearance rate is slower than previously assumed.

133 Both (11)C-acetate clearance rates, K(mono) (R(2) = 0.41, P = 0.006) and k2

134 Chlamydial clearance rates, local Th1 cytokine production, and host

135 ility is high, the genes underlying parasite clearance rate may be identified by genome-wide associat

136 idation, glucose carbon recycling, metabolic clearance rate (MCR) and non-oxidative disposal of gluco

137 Similarly, the metabolic clearance rate (MCR) in the control group increased 72%

138 -time (min) based on an exponential fit, and clearance rate (%/min) based on a linear fit.

139 The primary endpoints were duct-clearance rates, morbidity, operating time, and hospital

140 ing of lymphatic drainage patterns, particle clearance rates, nodal metastases, and differential tumo

141 receiving any sertraline dose averaged a CSF clearance rate of -0.37 colony forming units per mL per

142 DX-8951f had a half-life of 7.15 hours and a clearance rate of 1.65 L/h.m(2).

143 and 89% oral bioavailability and an in vivo clearance rate of 19.5 mL/min/kg in the rat.

144 wer at rest in contractile reserve-negative (clearance rate of [11C]acetate, 0.043+/-0.012 min(-1)) t

145 total-body radiation dose (TBD) based on the clearance rate of a preceding dosimetric dose.

146 wever, recent data also indicate a decreased clearance rate of Abeta in AD brains.

147 outcome was 2-week cerebrospinal fluid (CSF) clearance rate of cryptococcus, termed early fungicidal

148 The clearance rate of dense vesiculated RBC was biphasic and

149 quantitative time-series data showed a mean clearance rate of Ebola virus RNA from seminal fluid of

150 The permeability of PMEM was assessed by the clearance rate of Evans blue-labeled albumin, the activa

151 elta, loss rate of virus-producing cells; c, clearance rate of free virions; tau, delay until viral d

152 The rapid clearance rate of HCV(VLDF) indicates that association w

153 The clearance rate of hGH in rats was inversely proportional

154 he lungs of WT mice markedly accelerated the clearance rate of P. aeruginosa, demonstrating that lung

155 ificant association was detected between the clearance rate of productively infected cells and freque

156 gues at early times after injection, but the clearance rate of radioactivity from brain tissue varied

157 The fractional clearance rate of radiolabeled LDL was reduced to simila

158 sed swallowing frequency, thus improving the clearance rate of reflux within the esophagus.

159 The clearance rate of small HDL3 particles (density>1.13 g/m

160 Clearance rate of the remaining 62 patients was 100%.

161 cell-surface expression; but given the high clearance rate of thrombin, the high concentration of da

162 At the MTD, the median clearance rate of ultrafiltrable platinum was 9.7 L/h/m2

163 An endotoxin clearance rate of up to 1.3 x 10(8) was attained.

164 ting satellite species, although the overall clearance rate of vWF antigen was similar to wild type v

165 glomerular size selectivity by measuring the clearance rates of 3000- and 70,000-Da fluorescence-neut

166 easurements of the fractional production and clearance rates of Abeta in vivo in the human CNS to be

167 lic control (BUNs = 60 mg/dl), required urea clearance rates of approximately 900 ml/h and 1900 ml/h

168 a remarkable ability to predict in vivo drug clearance rates of both rapid and slow clearing drugs wi

169 ce are influenced by both the production and clearance rates of CEA.

170 The clearance rates of cellular reservoirs could not be dist

171 ased hepatic fatty acid synthesis, increased clearance rates of dietary triglycerides and increased h

172 estion of tolbutamide changed the calculated clearance rates of endogenously secreted insulin.

173 We compared the plasma concentrations and clearance rates of four solutes normally cleared by tubu

174 in genital mucosa, the in vivo expansion and clearance rates of HSV-2 are extremely rapid.

175 r, control and Pompe iPSC-CMs had comparable clearance rates of LC3-II-detected autophagosomes.

176 slower second component consistent with the clearance rates of normal control populations.

177 Clearance rates of NT-proET-1, ELDP and CT-proET-1 were

178 We sought to compare clearance rates of plasma human immunodeficiency virus t

179 s the effects of drugs on the production and clearance rates of proteins targeted as potential diseas

180 ibe a method to determine the production and clearance rates of proteins within the human central ner

181 climatic conditions on both acquisition and clearance rates of the bacterium, finding significantly

182 significantly reduced both the amplitude and clearance rates of the MPP(+)-evoked dopamine signal in

183 The biodistribution and clearance rates of the substrates are therefore directly

184 riability in mAb clearance is due to varying clearance rates of these different circulating CEA subsp

185 Rigorous estimates for clearance rates of untreated chlamydia infections are im

186 secretion with the plasma concentrations and clearance rates of urea and creatinine in patients recei

187 and apo B production rates were normal, but clearance rates of VLDL triglycerides and postlipolysis

188 linical cure, bacteriological cure, pathogen clearance rate or bacterial load.

189 .9 mmol/l), women with GDM had lower glucose clearance rates (P = 0.0001) but higher glucose producti

190 roduction rates (P = 0.01) but lower glucose clearance rates (P = 0.001) compared with normal pregnan

191 s, we also quantified the average creatinine clearance rate per glomerulus.

192 Despite comparable reductions in LDL clearance rates, plasma LDL levels are substantially low

193 herapy values, platelet count and creatinine clearance rate, predict IA outcome and stratify patients

194 nce (r = 0.51, P < 0.01), and the free water clearance rate (r = -0.90, P < 0.002).

195 duction of E. coli over 24 h, and calculated clearance rates ranged from 1.2 to 7.4 L hr(-1) bivalve(

196 ctly to the testis and has a rapid metabolic clearance rate, reducing the length of exposure in the l

197 n and carbachol, which produced near-maximal clearance rates regardless of prior treatment with CFTR

198 The dialytic clearance rates (relative to normal subjects) of unbound

199 compared to controls (55.6, 22.2, and 33.3% clearance rates, respectively).

200 odest but continual enhancement of reservoir clearance rates result in faster cure than abrupt, one-t

201 ding assays demonstrate an identical vesicle clearance rate shared by both the mutant and the wild-ty

202 the transgenic mice had glucose turnover and clearance rates similar to the controls, but showed a lo

203 G6 dendrimers also showed decreased renal clearance rate, slightly increased liver and spleen upta

204 the dynamics are primarily determined by the clearance rates, steady-state concentrations and respons

205 and, in the individual cases, unpredictable clearance rates suggest the necessity of dosimetry-based

206 mice, we failed to detect any differences in clearance rates, suggesting that differences in plasma a

207 cin (Alzal Corp, Palo Alto, CA) has a slower clearance rate than free doxorubicin, resulting in susta

208 lacking galactosylation had slightly faster clearance rates than other structures in the Fv domain.

209 ad lower free plasma dobutamine and dopamine clearance rates than those patients with serum creatinin

210 sinusoidal endothelial cells and a gammaDPGA clearance rate that was more rapid than the clearance re

211 that contained only structural proteins had clearance rates that were significantly higher than vacc

212 tomized or propranolol-treated rats revealed clearance rates that were the same or less than normal,

213 TPase alpha2) mice, which have reduced Na(+) clearance rates that would favor NCX1 reverse-mode opera

214 For different reinfection incidence and clearance rates, the model evaluated the accuracy of epi

215 te similar or lower viral titers and similar clearance rates, the variants caused more extensive dise

216 ngorged lysosomes and a slower autophagosome clearance rate upon autophagy induction by starvation.

217 The clearance rate was 0.032 episodes/day (95% confidence in

218 Mucus clearance rate was 11.3 +/- 9.9 mm/min in the Trendelenb

219 (5.2) mL/min and the mean plasma creatinine clearance rate was 20.7 (4.8) mL/min.

220 The mean plasma urea clearance rate was 22.7 (5.2) mL/min and the mean plasma

221 Maximal cAMP-dependent alveolar fluid clearance rate was 32.9 +/- 10.9 %/hr (p <.05).

222 The 3-year histological clearance rate was 81.8% (9/11) for lesions >10 mm, and

223 The histological clearance rate was 89.5% and 84.2%, respectively, at 3 a

224 When the creatinine clearance rate was considered as a continuous variable a

225 this effect of repeated swim to reduce 5-HT clearance rate was corticosterone dependent, as evidence

226 The spontaneous HCV clearance rate was found to be 33.1%.

227 In Pak2(-/-) mice, platelet clearance rate was increased, as was production of newly

228 Mucus clearance rate was measured through fluoroscopic trackin

229 Significant differences in the spontaneous clearance rate were estimated between age categories and

230 (-/-) mice, tear production, osmolarity, and clearance rate were evaluated before and after experimen

231 0.3 min) and slow (T1/2 = 10.9 +/- 1.4 min) clearance rates were accelerated (p < 0.0001) in Group 5

232 Free dobutamine and dopamine clearance rates were calculated.

233 Clearance rates were conveniently monitored by quantitat

234 Clearance rates were especially high in patients with co

235 Serotype-specific clearance rates were estimated by exponential regression

236 Subsequently, mucociliary clearance rates were measured by gamma scintigraphy of i

237 excretion rates and GFR determined by inulin clearance rates were measured during each of three treat

238 FDG clearance rates were measured in both normal and phloriz

239 Alveolar fluid clearance rates were measured in ex vivo perfused human

240 Tear clearance rates were measured with a fluorophotometer.

241 VLDL1, VLDL2, and CM TAG clearance rates were not different between groups.

242 To explain why parasite clearance rates were not faster with split dose regimens

243 Body weight, BP, and creatinine clearance rates were not significantly different among t

244 Interpatient variations in serum clearance rates were observed and were secondary to diff

245 Interpatient variations in serum clearance rates were observed and were secondary to diff

246 liver, although slightly different vascular clearance rates were observed.

247 These clearance rates were significantly higher at each time-p

248 ta confirmed that the plasma drug levels and clearance rates were similar for patients in both groups

249 gnments than those scenarios using predicted clearance rates, when comparing to bin placement using l

250 viral load and elevated antiretroviral drug clearance rates, which pose significant therapeutic chal

251 n the structure of these molecules and their clearance rate will further our ability to produce immun

252 duals could potentially exhibit altered SAHA clearance rates with differences in overall response.