ライフサイエンスコーパス: cleavage site

1 anase levels (TnaA mRNA has 16 putative YafQ cleavage sites).

2 t overlap or are immediately upstream of the cleavage site.

3 d inhibitory peptides derived from a cohesin cleavage site.

4 e site, thereby having minimal impact on the cleavage site.

5 ine teschovirus 1 (PTV-1) 2A autoproteolytic cleavage site.

6 d PAR1 signaling independent of the protease cleavage site.

7 catalysis and allow hydrolases to access the cleavage site.

8 ase in readout of information content at the cleavage site.

9 s including a preference for cytosine at the cleavage site.

10 U at a position seven nucleotides 3' to the cleavage site.

11 at the previously identified canonical Furin cleavage site.

12 se amino acids included a likely cathepsin L cleavage site.

13 e G40 and adenosine A32 close to the G53-U54 cleavage site.

14 tic and glutamic acids, are present near the cleavage site.

15 m-line mutation in the Aalpha chain thrombin cleavage site.

16 A)) introduces a functional signal peptidase cleavage site.

17 nal region of JP2 as the predominant calpain cleavage site.

18 resulting in RhoA activation at the nascent cleavage site.

19 rus by human SKI-1/S1P and defines the exact cleavage site.

20 ion of FcgammaRIIIA/CD16A and identified its cleavage site.

21 leavage peptide and blue light to uncage the cleavage site.

22 nt of the guide or target strands and at the cleavage site.

23 r a modified amide bond at the main protease cleavage site.

24 es, revealing the hydrophobic nature of Tiki cleavage sites.

25 genes, and binds RNA motifs downstream from cleavage sites.

26 cilitating access of the protease to the Gag cleavage sites.

27 d PAR1 signaling independent of the protease cleavage sites.

28 h the protease, 32 of which were outside Gag cleavage sites.

29 en RNase L-dependent and RNase L-independent cleavage sites.

30 s in predicting both Cas9 binding as well as cleavage sites.

31 more accurate prediction of Cas9 binding or cleavage sites.

32 JP2 with three N-terminal and one C-terminal cleavage sites.

33 d by mass spectrometry for identification of cleavage sites.

34 0 000 nucleotides with overlapping V1 and S1 cleavage sites.

35 luenza virus HA proteins that lack polybasic cleavage sites.

36 electing peptide cross-linkers with suitable cleavage sites.

37 degradation products revealed those initial cleavage sites.

38 and occurs over a greater number of backbone cleavage sites.

39 w Cas9-RNA interrogates DNA to find specific cleavage sites.

40 cleavage is regulated by acetylation of the cleavage sites.

41 dictions of other, distinct target substrate-cleavage sites.

42 tion by trypsin/chymotrypsin by exposing new cleavage sites.

43 We identify the metalloprotease cleavage site 3 aa upstream of the predicted GPI anchor

44 d S97 residues in proximity of the caspase-7 cleavage site, 30-DETD-33, inhibits caspase-7 digestion

45 long the translocation coordinate toward the cleavage site, a 4-nucleotide RNA experiences a free ene

46 te-directed (Arg-to-Ala) mutagenesis of this cleavage site abolished matriptase-mediated APP processi

47 The C62-A63 step at the cleavage site adopts a splayed-apart orientation, with f

48 o investigate whether this potential trypsin cleavage site affects sensitivity to trypsin, a primary

49 The determination of important cleavage sites allowed the development of selectively mo

50 the junction of the signal peptidase (Spase) cleavage site along with a well conserved lipobox motif.

51 The smaller conformer of melittin has fewer cleavage sites along the peptide backbone than the large

52 at the simple CAC motif that defines the RSS cleavage site and are largely confined within convergent

53 tracellular site different from the thrombin-cleavage site and thus initiates biased receptor signali

54 specifically bind to the GPIbalpha shedding cleavage site and to inhibit its shedding.

55 Human IL-37 has a caspase-1 cleavage site and translocates to the nucleus upon LPS s

56 orly understood; MMPs have limited access to cleavage sites and are inhibited by tension on the fibri

57 We defined the cleavage sites and boundaries between the processed prot

58 e genomes, enriched with eukaryotic protease cleavage sites and combined with additional domains to f

59 modifications were specific to the Cas9-gRNA cleavage sites and consisted of small deletions or inser

60 ytical methods are required to identify main cleavage sites and degradation products of GalNAc conjug

61 e to a database of experimentally determined cleavage sites and experimentally validated for four epi

62 d peptide substrates on the basis of protein cleavage sites and found similar catalytic efficiencies

63 of computational analysis to predict calpain cleavage sites and in vitro calpain proteolysis reaction

64 aling from PARs is influenced by alternative cleavage sites and the physical interactions within the

65 tified the protease responsible, located the cleavage site, and demonstrated that cleavage likely occ

66 peptides, frequency of peptides with missed cleavage sites, and the reproducibility of FASP.

67 ogen atoms N1 and N3 of the adenine-6 at the cleavage site are indispensable for cleavage.

68 only nine amino acids flanking the putative cleavage site are necessary and sufficient to accurately

69 Intramembrane cleavage sites are accessible and not part of the struct

70 However, missed cleavage sites are frequently observed when acidic amino

71 s no apparent sequence requirements, and the cleavage sites are measured from the 5' end of the DNA s

72 The identified cleavage sites are not at a fixed distance position rela

73 The molecular paints, which block trypsin cleavage sites, are excluded from the binding interface.

74 cleavage sites Leu-81 and Leu-148, autolytic cleavage site Arg-122, and restoration of the missing di

75 HPV16 L2 contains two consensus cleavage sites, Arg5 (2RHKR5) and Arg12 (9RTKR12).

76 n, which inserts the segment upstream of the cleavage site as an extra beta-strand in a central beta-

77 Serial truncation mapping identified the cleavage site as Leu(90)/Val(91) in the 95-amino acid AD

78 g a different insertion at the hemagglutinin cleavage site, as well as nine nucleotide differences at

79 ndeed, computational prediction of substrate-cleavage sites associated with MMPs is a challenging pro

80 ediated degradation was due to an additional cleavage site at Leu-148 in the autolysis loop and the l

81 The identification of the 3Cpro cleavage site at the C terminus of N supported previous

82 d at the P1' position of the NS2B/3 protease cleavage site at the carboxy terminus of the C protein.

83 haFXIIa (FXII-R353A), or lacking the 3 known cleavage sites at Arg334, Arg343, and Arg353 (FXII-T, fo

84 oughput sequencing technology to define TOP2 cleavage sites at single-base precision, and use the tec

85 582-nucleotide insertion, flanked by 3C(pro) cleavage sites at the 5' and 3' ends, was found in the 2

86 ed to contain conserved thrombin-susceptible cleavage sites based on sequence analysis, and heavy cha

87 rate prior to T1 closure such that the U5-A6 cleavage site becomes embraced to achieve its cleavage c

88 A, whereas A4020G causes S1108G in a 3C(pro) cleavage site between 2B and 2C.

89 In this position the cleavage site between CA and p10 appears to be inaccessi

90 Here we show that replacement of the cleavage site between gp120 and gp41 in a lead soluble g

91 Specifically, we replaced the furin cleavage site between gp120 and gp41 with Gly-Ser linker

92 Next, we replace the cleavage site between gp120 and gp41 with various linker

93 amino acid residues 534 (P4 position of the cleavage site between nsP1 and nsP2) and 1052 (S4 subsit

94 terized by increased processing speed of the cleavage site between nsP1 and nsP2.

95 ogical inhibition profile and the identified cleavage site between two juxtaposed cysteine residues a

96 d substitution T860N in the protease 2A(pro) cleavage site between VP1 and 2A, whereas A4020G causes

97 centrin deficiency or mutation of a separase cleavage site blocked DNA damage-induced PCM expansion.

98 Mutation of the cleavage site blocks cleavage and inhibits autophagy in

99 altered the cleavage efficiency of specific cleavage sites both within and between genogroups.

100 hat cells clear trailing chromatids from the cleavage site by undergoing two phases of cell elongatio

101 ncluding processing of 8 of the 13 substrate cleavage sites by dengue virus NS2B/NS3 protease.

102 Reversing this RAG-driven depletion of cleavage sites by insertion of strong recombination sign

103 strate cleavages so that conservation of the cleavage site can be assessed.

104 ures with Pb(2+) and the modification at the cleavage site captured the pre-catalytic state of the RN

105 The conserved cleavage site, close to the L2 N terminus, confounds obs

106 n HIV-1 subtype-B, specific mutations in Gag cleavage sites (CS) are associated with treatment failur

107 that Rio1-mediated dissociation of Pno1 from cleavage site D is the trigger for final 18S rRNA matura

108 for assessment of the processing of putative cleavage sites derived from the GPCs of newly discovered

109 We find that the distance between two Top1 cleavage sites determines the deletion size and that thi

110 ble in the serum of mice, mutating the furin cleavage site did not alter the stimulation of hepcidin

111 protease activity both in vitro and at H3NT cleavage sites during osteoclastogenesis.

112 Two mutations, one in the fusion (F) protein cleavage site, F117S (F117S), and another in hemagglutin

113 hlight the importance of a single maturation cleavage site for both infectious particle production an

114 In PAM-1/OSX, a cleavage site for furin-like convertases was exposed, ge

115 These thermosensors contain a cleavage site for RNase E, an enzyme native to Escherich

116 re polar C-terminal region that contains the cleavage site for the signal peptidase.

117 pr construct, in which 2xCL denotes a tandem cleavage site for the viral protease.

118 referenced information about recognition and cleavage sites for both restriction enzymes and methyltr

119 ss-linking with peptides containing specific cleavage sites for MMP-9.

120 age site within PBS1 can be substituted with cleavage sites for other pathogen proteases, which then

121 QGAP1 amino acid sequence revealed potential cleavage sites for proteases of the proprotein convertas

122 ght peptides encompassing predicted protease cleavage sites for Serp-1 and NSP were synthesized and t

123 We also verified the cleavage sites for six targets using RNA ligase-mediated

124 ide and residues downstream of the canonical cleavage site form an extended alpha-helix in the ER mem

125 a virus HA proteins that contain a polybasic cleavage site from pH-induced conformational changes dur

126 overed that A673V mutation shifted the BACE1 cleavage site from the Glu(11) to the Asp(1) site, resul

127 ) the presence or absence of endonucleolytic cleavage sites, (g) control of intracellular ribonucleas

128 e frequently applied to analyze and validate cleavage sites guided by microRNAs (miRNAs).

129 an "immature" Chikungunya virus in which the cleavage site has been mutated to inhibit proteolysis.

130 preferred sequence motif spanning most SMG6 cleavage sites has been discovered and validated by muta

131 acid residues in close proximity to trypsin cleavage sites has unpredictable consequences for the di

132 Sequences closer to the cleavage site have critical but redundant roles in both

133 Three classes of cleavage sites have been identified and characterized: (

134 domain identification, location of protease cleavage sites, identification of signal peptides, prote

135 The primary cleavage site identified by mass spectrometry was betwee

136 Site-directed mutagenesis of putative cleavage sites identified Gly374 and Gly552 as the sites

137 The F117S mutation in the F protein cleavage site improved F protein cleavage efficiency whi

138 ase domain adjacent to the target DNA strand cleavage site in a conformation essential for concerted

139 hat cells clear trailing chromatids from the cleavage site in a two-step cell elongation and demonstr

140 edominantly occurring before exposure of the cleavage site in A2, an observation that is supported by

141 n collagen cross-linking sites and the MMP-1 cleavage site in collagens I and II.

142 dition, we identified a pH-sensitive dispase cleavage site in hexon HVR1, which depends on the same s

143 owers blood glucose in vivo, defined the OXM cleavage site in serum, and this information was used to

144 o 21-bp direct repeats and a major terminase cleavage site in the phage genome.

145 soschizomer I-BmoI which targets a different cleavage site in the thymidylate synthase gene, recapitu

146 ed accessibility of the enzymes to potential cleavage sites in folded proteins.

147 nus regulates accessibility of extracellular cleavage sites in gamma-ENaC.

148 We have identified caspase-3 cleavage sites in GIRK1 ((387)ECLD(390)) and GIRK2 ((349

149 In this manner, the SMG6 cleavage sites in hundreds of endogenous NMD targets in

150 Site-directed mutagenesis of the phytaspase cleavage sites in prosystemin abrogated not only the phy

151 ftware that predicts the presence of the MMP cleavage sites in the peptide sequences.

152 positional preferences were consistent with cleavage sites in the protein GFPssrA by ClpXP1P2.

153 Here I examine the known cleavage sites in the two ITS regions and their position

154 Our analysis of cleavage sites indicates that cleavage requires multiple

155 ivate NF-kappaB signaling; thus, mutation of cleavage sites inhibited the induction of apoptosis by t

156 proteases upon cleavage of various norovirus cleavage sites inserted into a linker region separating

157 at it is processed proteolytically at a WGSS cleavage site into a heterodimer.

158 In contrast, introduction of a polybasic cleavage site into Israel810 HA leads to pseudoviruses t

159 (E168K) that introduces a potential trypsin cleavage site into the CPB protein of strain JGS1076.

160 The cleavage site is 11/9 nucleotides downstream of the A re

161 ither the mRNA polyadenylation signal and/or cleavage site is an efficient strategy to down-regulate

162 icate that proteolysis at the D266 caspase-7 cleavage site is an important mediator of ataxin-7 neuro

163 ologically relevant on the basis that such a cleavage site is likely to be conserved.

164 For each VWF monomer, the ADAMTS13 cleavage site is located deeply buried inside the VWF A2

165 The -cleavage site is only one amino acid N-terminal to a Val

166 This should help establish whether or not a cleavage site is physiologically relevant on the basis t

167 In addition, we reveal that an elastase 2 cleavage site is present between FNIII EDA and FNIII 12.

168 de chain of the Thr-192 residue at +1 of the cleavage site is required for an attack on the preceding

169 At low temperatures, the cleavage site is sequestered in a stem-loop, and gene ex

170 n amino acid motif similar to the phytaspase cleavage site is shared by the human gastrointestinal pe

171 the domain immediately downstream of the S2' cleavage site is the FP (amino acids 798-818 SFIEDLLFNKV

172 Because the cleavage site is well preserved and the hydrolysis of pe

173 suggest that host DSB repair at CRISPR/Cas9 cleavage sites is a novel and important pathway that may

174 ctarepeat domain and N-terminal to the alpha-cleavage site, is thought to arise from the action of re

175 eolytic cleavage at the prostasin/kallikrein cleavage site (K181-V182 and mAbprostasin) to examine hu

176 , thermolysin/neutral protease share similar cleavage sites, L( downward arrow)G and P( downward arro

177 ed "opening" resulting in exposure of the S2-cleavage site leading to activated Notch1 signaling.

178 s achieved by simultaneous mutations of CTRC cleavage sites Leu-81 and Leu-148, autolytic cleavage si

179 trimental APP mutation at the beta-secretase cleavage site linked to early-onset AD found in a Swedis

180 followed by site-directed mutagenesis of the cleavage sites links receptor activation to specific ami

181 ibonuclease H (RH) domain contains an occult cleavage site located near its center, cleavage must occ

182 ism whereby protease recognizes distinct Gag cleavage sites, located in the intrinsically disordered

183 e PICS (proteomic identification of protease cleavage sites) method are similar for both KLK2 variant

184 duction in pericentrin-deficient or separase cleavage site mutant-expressing cells, and an increase i

185 pro-TGF-beta1 with the proprotein convertase cleavage site mutated to mimic the structure of the TGF-

186 ral pocket in proximity to the MMP-9 zymogen cleavage site near Arg-106, which is distinct from the c

187 We mapped a charge-dependent putative cleavage site near the membrane-proximal domain necessar

188 mains including the lack/excess of enzymatic cleavage sites, nonunique peptide sequences, impaired pe

189 Mutagenesis of the cleavage site nullified the processing event, resulting

190 that the Q193-G194 pair within GSDMD is the cleavage site of 3C.

191 APP mutation, shifted the preferential beta-cleavage site of BACE1 in APP from the Glu(11) site to t

192 nto short CRISPR RNA guides that specify the cleavage site of Cas nucleases in the genome of the inva

193 we identified haplotypes with hemagglutinin cleavage site of different lengths.

194 2 (PPPY) as well as the late domain/protease cleavage site of matrix (LYPAL), by mass spectrometry an

195 lycine-to-alanine mutation in the N-terminal cleavage site of protein VI that profoundly impacts prot

196 asic amino acids (KGKRTAR/G) at the protease cleavage site of the HA protein, which were previously f

197 posure, and relaxation studies show that the cleavage site of the lipid-signaling protein intermediat

198 Finally, by protecting the cleavage site of the Na(+)-specific DNAzyme with a photo

199 ctural features of the 20S pre-rRNA near the cleavage site of the nuclease, Nob1.

200 Most peptides were released at the cleavage sites of cathepsins B and D, which thus play an

201 r outside the active site of protease or the cleavage sites of Gag (located within intrinsically diso

202 g molecule Jagged 1 (Jag1).Wealso mapped the cleavage sites of Jag1 by ADAM10 and ADAM17.

203 e synthetic peptides mimicking the predicted cleavage sites of neurotoxin precursors.

204 y bound ligands did not mask any proteolytic cleavage sites of pepsin, trypsin or chymotrypsin.

205 Structural motifs at the cleavage sites of starch, beta-glucan and arabinoxylan f

206 e, were found to be abundant in the specific cleavage sites of the cocoa enzyme.

207 that the mutant VWF gives access to multiple cleavage sites of the VWF multimer at the same time.

208 nce surrounding critical residues within the cleavage site on protease specificity.

209 n of MMP-2, -3, -7, -8, -9 and -12 substrate-cleavage sites on independent tests.

210 downward arrowSAGGSVA, downward arrow shows cleavage site), on phage or coated it onto silver nanopa

211 Mapping of cleavage sites onto three-dimensional structures of HEPE

212 Substrates with cleavage sites outside the membrane can be cleaved but l

213 These potential cleavage sites overlap with known motifs for lysine acet

214 e activity for the preferred residues at the cleavage site (P1, P1') and nearest-neighbor positions (

215 We synthesized a peptide beginning at the cleavage site (p1158/59, amino acids 1159 to 1173) to in

216 Three protease:cleavage site pairs from Potyvirus are shown to be ortho

217 ularly at the hemagglutinin (HA) proteolytic cleavage site (PCS) that can affect virus activation and

218 y threefold in human coding sequences to one cleavage site per approximately 11 bp.

219 otein sequences for the presence of protease cleavage sites, Pfam domains, glycosylation sites, signa

220 termed Proteomic Identification of protease Cleavage Sites (PICS).

221 This cleavage site preceded the N-terminal domain of decorin

222 hat performs improved off-target binding and cleavage site predictions.

223 ch differs from the poliovirus 3C proteinase cleavage site previously identified.

224 nce 5-A/CCGGT-3 and cuts it ('/' denotes the cleavage site) producing staggered DNA ends.

225 ture of PDGF-B predicted that the matriptase cleavage site R(340)R(341)GR(343)A is within loop III of

226 structural homogeneity at the signal peptide cleavage site regardless of the native secretory route.

227 There are up to eight pepsin-cleavage sites remaining within the double chain peptide

228 tion requires unmasking of a metalloprotease cleavage site remote from the site of ligand binding, ra

229 pared human FXII variants lacking the Arg353 cleavage site required for conversion to alphaFXIIa (FXI

230 Lastly, we demonstrate that dentilisin cleavage sites reside within critical functional domains

231 t 4 out of 4 and 7 out of 9 of the predicted cleavage sites, respectively.

232 Amino acid substitution at the cleavage site resulted in no renal excretion of AIM.

233 type DNAJC14 affected the NS3/4A and NS4A/2K cleavage sites, resulting in altered NS3-to-NS3-4A ratio

234 lectrophoresis and LC-MS/MS to determine the cleavage site(s) and Asn(347) glycosylation as a functio

235 P673 regulates APP processing, and the BACE1 cleavage site selection is critical for amyloidogenesis

236 PP673 regulates APP processing and the BACE1 cleavage site selection is critical for amyloidogenesis

237 Q mutation overlaps with the predicted MMP-9 cleavage site sequence.

238 The conjugate containing the enzymatic cleavage site showed high extracellular stability and fa

239 nfolding of this domain, thereby leaving the cleavage site solvent-exposed and ready for cleavage.

240 zed that other proteins possessing potential cleavage sites stabilized in a similar conformation migh

241 dering MMPs with few experimentally verified cleavage sites, such as for MMP-2, -3, -7, and -8.

242 nds are at or near preferred gamma-secretase cleavage sites, suggesting that the sequence of APP and

243 r proteinase substrates and their respective cleavage sites suggests novel mechanisms of the effect o

244 ts 3'-end processing of pre-miRNAs on Drosha cleavage site that correlates with miRNA-offset RNAs (mo

245 nd to exhibit superior PAR1 proteolysis at a cleavage site that selectively mediates cytoprotective s

246 s of full-length decorin but also harbored a cleavage site that was not found in atrial appendages fr

247 As by juxtaposing poly(A) signals (PASs) and cleavage sites that are otherwise too far apart.

248 However, S proteins have two distinct cleavage sites that can be activated by a much wider ran

249 o acid precursor protein containing multiple cleavage sites that, when cleaved, releases multiple bio

250 alpha2delta constructs containing artificial cleavage sites, that this processing is an essential ste

251 by an increased availability of the ADAMTS13 cleavage site through A2-domain-fold thermodynamic desta

252 /P1') motif within the GFD is the matriptase cleavage site through which matriptase can deactivate PD

253 a-helix in the ER membrane, which covers the cleavage site, thus preventing cleavage.

254 usly described canonical site is a secondary cleavage site to a prerequisite cleavage in a newly char

255 via the insertion of a Factor Xa proteolytic cleavage site to acquire the optimal glutamate residue a

256 has a modification at the fusion protein (F) cleavage site to reduce the efficiency of F protein clea

257 ng domain (CBD), a fluorescent protein and a cleavage site to release it from the plasma membrane.

258 distribute CTCF/cohesin occupancy rewire DNA cleavage sites to novel loop anchors.

259 that the T210M exchange affects proteasomal cleavage site usage within the mutgp100201-230 polypepti

260 ng upon total degradation rate and substrate cleavage-site usage.

261 rin from accessing L2 by occluding the furin cleavage site via direct binding to the viral capsid.

262 pecifically, an out membrane protease (OmpT) cleavage site was engineered into the switch loop of RF1

263 stalk with flexible linkers, and a Factor Xa cleavage site was inserted immediately in front of Ex-4

264 The cleavage site was mapped between Asp(342) and Asn(343).

265 Deletion of the strand after the cleavage site was observed in zonula occluden-1 and some

266 s residue is just before the gamma-secretase cleavage site, we then investigated whether the p75(alph

267 Indels localized to the CRISPR/Cas9 cleavage site were major contributors to CRISPR gRNA res

268 Hydrolysis rates at tryptic cleavage sites were also shown to be affected by differe

269 nd the kinetic constants for selected missed cleavage sites were calculated.

270 RNase L-dependent cleavage sites were evident at discrete locations in IAV

271 Signal peptidase I (SpI) cleavage sites were found in 463 of these putative secre

272 by western blot analysis, and five putative cleavage sites were functionally characterized.

273 Within its protein core, 18 different cleavage sites were identified.

274 For IgG2, two pepsin cleavage sites were identified; anti-hinge reactivity wa

275 th HB101(pPic1) culture supernatants, and C3 cleavage sites were mapped by fluorescence resonance ene

276 mRNA was visualized by northern analyses and cleavage sites were mapped.

277 Amino acids surrounding identified cleavage sites were mutated in an attempt to increase re

278 eavage at more than one site, and all of the cleavage sites were within, or in close proximity to, an

279 showed that AtCEP2 accepts proline near the cleavage site, which is a rare feature specific for KDEL

280 ate and determined the primary and secondary cleavage sites, which suggests a strong preference for L

281 ssing-alternative splice sites, introns, and cleavage sites-which are often rare and lowly expressed

282 wo canonical sites adjacent to the necessary cleavage site, while CsrD acts by overcoming CsrA-mediat

283 Replacing the natural furin cleavage site with a HRV 3C protease site, we show how t

284 ctural basis of coevolution at the Gag p1-p6 cleavage site with the nelfinavir (NFV) resistance D30N/

285 onstrate that replacement of MNV polyprotein cleavage sites with the GI or GII equivalents, with the

286 id position 5 upstream of the signal peptide cleavage site, with cleavage-inducing glycine (G) result

287 onal analysis, we identified the FCV-induced cleavage site within G3BP1, which differs from the polio

288 We show that the AvrPphB cleavage site within PBS1 can be substituted with cleava

289 gin at or after the canonical beta-secretase cleavage site within the amyloid beta-protein precursor.

290 Previous studies identified a caspase-3 cleavage site within the amyloid-beta precursor protein,

291 leases and small RNA guides, which specify a cleavage site within the genome of the invader.

292 cleaved the aggrecan core protein at a novel cleavage site within the interglobular domain.

293 all cases the existence of a unique trypsin cleavage site within the membrane domain (out of 16 pote

294 deep-sequencing methods to identify RNase L cleavage sites within host and viral RNAs from IAV PR8De

295 reveal the frequency and location of RNase L cleavage sites within host and viral RNAs.

296 actions, we identified four putative calpain cleavage sites within JP2 with three N-terminal and one

297 and were predicted by algorithms to contain cleavage sites within proteins by cysteine-dependent asp

298 i) RNase L-dependent and RNase L-independent cleavage sites within ribosomal RNAs (rRNAs) and (iii) 2

299 Flap closure traps the Gag cleavage sites within the catalytic cleft of protease.

300 the conservation of secondary structures and cleavage sites within the ITS regions will improve evolu