ライフサイエンスコーパス: cleft lip and palate

1 splicing regulatory protein (Esrp1) develop cleft lip and palate.

2 ome (VWS), the most common syndromic form of cleft lip and palate.

3 nomalies and facial dysmorphology, including cleft lip and palate.

4 he FGF family has also been shown to lead to cleft lip and palate.

5 on the current knowledge of the etiology of cleft lip and palate.

6 eal pterygium syndrome, 2 syndromic forms of cleft lip and palate.

7 variation in IRF6 confers risk for isolated cleft lip and palate.

8 d to improve nasal symmetry in patients with cleft lip and palate.

9 th prolonged treatment trajectories, such as cleft lip and palate.

10 rimary cilium, and these patients often have cleft lip and palate.

11 amilies with autosomal dominant nonsyndromic cleft lip and palate and 3 families with autosomal domin

12 We studied a patient with isolated cleft lip and palate and a balanced chromosomal transloc

13 syndrome (VWS) is a common form of syndromic cleft lip and palate and accounts for approximately 2% o

14 tudies showed that mutations in IRF6 lead to cleft lip and palate and mandibular abnormalities.

15 ed from MMF to SRL during late pregnancy had cleft lip and palate and microtia) and three SA.

16 ere craniofacial defects including bilateral cleft lip and palate and tongue agenesis, following the

17 tations in several candidate genes may cause cleft lip and palate, but definitive evidence regarding

18 been shown to be an important contributor to cleft lip and palate, but the functional variant leading

19 ate and accounts for approximately 2% of all cleft lip and palate cases.

20 s are candidate genes for genetic disorders (cleft lip and palate, certain forms of cancer) or solute

21 Cleft lip and palate (CL/P) is a common disfiguring birt

22 also observed wider de novo deletions among cleft lip and palate (CLP) cases than seen among cleft p

23 d MAFB and isolated cleft lip only (CLO) and cleft lip and palate (CLP).

24 ed with syndromic and non-syndromic forms of cleft lip and palate, consistent with a role for Irf6 in

25 a positive dose response among infants with cleft lip and palate+ (for light smokers, odds ratio (OR

26 Seventeen percent of those with cleft lip and palate had another defect compared with 9%

27 y drain saliva, and patients with the common cleft lip and palate have a higher prevalence of dental

28 ions (p = 0.001), and with SNP rs3923086 and cleft lip and palate in Asian populations (p = 0.004).

29 signaling pathway have been associated with cleft lip and palate in humans and mice, the mechanisms

30 Cleft lip and palate is a common human birth defect, and

31 The proband presented with bilateral cleft lip and palate, malformed auricles, and bilateral

32 isolated defects--cleft lip alone (n = 334), cleft lip and palate (n = 494), or cleft palate alone (n

33 ditional malformations: cleft lip+ (n = 58), cleft lip and palate+ (n = 140), or cleft palate+ (n = 2

34 Nonsyndromic cleft lip and palate (NS CLP) is a complex birth defect

35 most recent advances in the understanding of cleft lip and palate occurrence.

36 shortened fifth fingers (one), microtia with cleft lip and palate (one), microtia alone (one), and ne

37 15 cleft lip and palate organisations totalled 26% of both

38 es a constellation of abnormalities, such as cleft lip and palate, pigmentary retinopathy, and multip

39 petitive urinary tract infections, bilateral cleft lip and palate, retinopathy, and gut malrotation.

40 Recently, we identified a family in which cleft lip and palate segregated in two of three generati

41 surgery such as ophthalmology (88, 28%) and cleft lip and palate surgery (70, 22%) were also frequen

42 s are directed at ophthalmology, followed by cleft lip and palate surgery.

43 Cleft lip and palate syndromes are among the most common

44 Cleft lip and palate syndromes in humans are associated

45 For boys, the risk was greater for cleft lip and palate than for cleft lip only (odds ratio

46 involvement in an autosomal dominant form of cleft lip and palate, Van der Woude's syndrome.

47 The risk of cleft lip only, but not of cleft lip and palate, was increased for twins (odds rati

48 ily of three affected siblings with isolated cleft lip and palate, we discovered that they share a no

49 20 patients with complete unilateral cleft lip and palate were prospectively recruited.

50 he disorder is an autosomal dominant form of cleft lip and palate with lip pits, and is the most comm